Clinical trials: Pain, Chronic Disease
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Chronic Pain, Opioid Misuse
French Version of POMI Scale
French translation and validation of the Prescription Opioid Misuse Index scale (POMI), a brief questionnaire to assess opioid prescription misuse.
- Trial name
- POMI (NCT04979364)
- Volunteers
- 154 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Pain, Opioid-use Disorder
Validation of the ASI-SR Form in a Population of Chronic Non-cancer Pain Patients
The Swedish version of ASI-SR has shown good feasibility in assessment of addiction patients functioning compare to long and time-consuming ASI, which is upp to date golden standard in Sweden.
- Conditions
- Chronic Pain, Opioid-use Disorder, Quality of Life, Risk Reduction
- Trial name
- ASI-SR (NCT04998734)
- Testing
- ASI-SR
- Where
- Sweden
- Volunteers
- 1 people
- Sponsor
- Uppsala University
Chronic Pain
Acupuncture and Chiropractic Care for Chronic Pain in an Integrated Health Plan
Recent research examines many types of complementary and alternative (CAM) therapies. However, "real-world" use of CAM has been largely overlooked.
- Trial name
- Relief (NCT01345409)
- Where
- United States
- Volunteers
- 1,242 people
- Sponsor
- Kaiser Permanente
Postoperative Pain, Postoperative Nausea and Vomiting
High-Dose Steroid for Knee Arthroplasty Patients Expected to Have Postoperative Pain
The purpose of the Study is to test a higher dose of steroids(Dexamethasone) given just prior to surgery in the setting of Fast-Track Knee surgery with Arthroplasty in a group of expected High Pain Responders and the effect on…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Knee Osteoarthritis, Perioperative/Postoperative Complications
- Trial name
- NCT03763734
- Testing
- Dexamethasone
- Where
- 2 sites in Denmark
- Volunteers
- 88 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Migraine, Migraine in Adolescence
Mindfulness-Based Intervention for Adolescents With Chronic Migraine
The goal of this study is to assess feasibility and acceptability of a mindfulness-based intervention adapted for adolescents with migraine to inform a future randomized trial assessing effects of the intervention on…
- Trial name
- NCT06414109
- Testing
- BREATHE-Migraine
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Colorado, Denver
Alzheimer&Amp;#39;s Disease, Other Dementias
Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients
This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and online chair yoga (OCY) to manage…
- Trial name
- NCT07303998
- Testing
- Active tDCS paired with active online chair yoga
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Arizona
Angina Pectoris
Testosterone Therapy on Angina Threshold and Atheroma in Patients With Chronic Stable Angina
This study aims to address the following questions on the effects of testosterone therapy in men with coronary ischaemia: Does the anti-anginal effect persist long term? Many of the published studies are acute single dose trials…
- Trial name
- NCT00131183
- Testing
- Nebido
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Vulvodynia, Vulvar Vestibulitis
Pregabalin for the Treatment of Vulvodynia
The purpose of this study is to determine whether pregabalin is effective in the treatment of vulvodynia.
- Trial name
- NCT00853229
- Testing
- pregabalin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Tinnitus, Pain
Modulating Mechanisms in Patients With Chronic Subjective Tinnitus and/or Chronic Pain
This is a cross-sectional investigation into modulating mechanisms in patients with chronic subjective tinnitus, which will compare 4 patient groups namely chronic tinnitus with chronic pain, chronic tinnitus without chronic…
- Trial name
- NCT05186259
- Testing
- Self-reported signs of central sensitization, Objective signs of central sensitization, Audiological outcome measures (audiometry, tinnitus analysis, uncomfortable loudness) in tinnitus patients with and without pain
- Where
- Belgium
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- University Ghent
Chronic Kidney Diseases, Pain, Procedural
Effect of 4-7-8 Breathing on AV Fistula Needle Pain in Dialysis Patients
For many hemodialysis patients, needle insertion into the vascular access site (fistula) is a significant source of pain and anxiety.
- Conditions
- Chronic Kidney Diseases, Pain, Procedural, Arteriovenous Fistula
- Trial name
- NCT07700680
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
Knee Osteoarthritis, Arthropathy of Knee Joint
Outcome After Total Knee Arthroplasty Under General or Spinal Anesthesia
Previous retrospective database studies suggest that total knee arthroplasty (TKA) surgery under spinal anesthesia has less complications than when performed under general anesthesia.
- Conditions
- Knee Osteoarthritis, Arthropathy of Knee Joint, Knee Pain Chronic, Rheumatoid Arthritis
- Trial name
- NCT03364088
- Testing
- Spinal anesthesia with tourniquet, Spinal anesthesia without tourniquet, General anesthesia with tourniquet
- Where
- Finland
- Volunteers
- 402 people
- Sponsor
- Riku Antero Palanne
Interstitial Cystitis, Painful Bladder Syndrome
Physical Therapy Trial for Pelvic Pain
The purpose of this study is to determine if a randomized trial of physical therapy for pelvic pain is feasible.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Chronic Prostatitis, Chronic Pelvic Pain Syndrome
- Trial name
- UPPCRN-RCT#1 (NCT00434343)
- Testing
- Global Therapeutic Massage (GTM), Myofascial physical therapy (MPT)
- Where
- 5 sites in United States
- Volunteers
- 47 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Musculoskeletal Pain
Piloting a Novel Peer Support Pain Self-Management Intervention (Project CONNECT)
The proposed study will test the feasibility and acceptability of an 8-week home-based reciprocal peer support pain self-management intervention (CONNECT) for women Veterans with chronic musculoskeletal pain.
- Trial name
- CONNECT (NCT04229134)
- Testing
- Project CONNECT
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Chronic Pain, Musculoskeletal Pain
Feasibility of At-Home Telehealth Yoga for Treating Chronic Pain
This feasibility study will evaluate yoga as a treatment for chronic musculoskeletal pain. The experimental treatment is yoga delivered via a tablet computer to participants at home ("teleyoga").
- Trial name
- NCT04074109
- Testing
- Teleyoga, In-person yoga
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Palo Alto Veterans Institute for Research
Spondylitis, Ankylosing
16-week Efficacy and 3-year Safety, Tolerability and Efficacy of Secukinumab in Active Ankylosing Spondylitis Patients
The purpose of this study was to generate 16-week efficacy data, as well as up to 3-year efficacy, safety and tolerability data in subjects with active AS despite current or previous NSAID, DMARD and/or anti-TNF therapy.
- Trial name
- MEASURE 3 (NCT02008916)
- Testing
- Secukinumab
- Where
- 57 sites in United States, Belgium and 8 more
- Volunteers
- 226 people
- Sponsor
- Novartis Pharmaceuticals
Restless Legs Syndrome, Chronic Pain
Effects of Transcutaneous Vagus Nerve Stimulation in Chronic Pain Patients and Healthy Controls
The tVNS-PP trial investigates the effects of transcutaneous vagus nerve stimulation (tVNS) on autonomic functions, immune responses, and disease severity in chronic pain and restless legs syndrome (RLS) patients as compared to…
- Trial name
- tVNS-PP (NCT05007743)
- Testing
- Transcutaneous vagus nerve stimulation
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Osteoarthritis, Knee Pain Chronic
Effectiveness of Curcumin-based Food Supplement in Reducing Pain and Inflammatory Component in Osteoarthritis
INTRODUCTION The treatment of OA is mostly symptomatic and includes the use of analgesics, NSAIDs, exercise and even surgery. However, the use of long-term NSAIDs is associated with potentially serious side effects.
- Trial name
- FENOXI-1900 (NCT04207021)
- Testing
- Experimental: Curcumin derivate
- Volunteers
- 134 people
- Sponsor
- KOS Care SRL - Istituto di Riabilitazione Santo Stefano
Quality of Life, Infection, Bacterial
Retrospective Chart Review of Treataprost Added to Antibiotic Treatment in Patients With Chronic Prostatitis
Multicenter, Retrospectivecohort study in patients with Chronic Prostatitis, Chronic Bacterial Prostatitis (Category II) and Chronic Pelvic Pain Syndrome (Category IIIA, IIIB) and 140 patients without other significant…
- Conditions
- Quality of Life, Infection, Bacterial, PSA, Prostatitis
- Trial name
- Treataprost (NCT05306314)
- Testing
- TREATAPROST
- Where
- 4 sites in Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- GMG Grand Medical
Chronic Pain, Musculoskeletal Pain
Topical Cannabis for Chronic Musculoskeletal Pain
Our proposal objective is to evaluate if state-regulated topical CBD-based products relieve chronic musculoskeletal pain and/or absorb into the bloodstream.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Joint Pain
- Trial name
- NCT05908552
- Volunteers
- 77 people
- Sponsor
- University of Colorado, Denver