Clinical trials: Pain, Chronic Disease
Traumatic Brain Injury, Pain
Characterization & Treatment of Chronic Pain After Moderate to Severe TBI
This is a five year multi-site, cross sectional, observational study designed to examine chronic pain and pain treatment after moderate to severe TBI.
- Trial name
- NCT03739307
- Where
- 13 sites in United States
- Volunteers
- 3,805 people
- Sponsor
- Craig Hospital
Endometriosis
Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in Women With Chronic Pelvic Pain
In our study, by evaluating the serum and vaginal-peritoneal fluid levels of Relaxin, Matrix Metalloproteinase-2 and Interleukin-6 in women over 35 years of age with chronic pelvic pain, the investigators aimed to reveal their…
- Trial name
- NCT06628479
- Testing
- interleukin, enzyme, hormone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Neck Pain, Low Back Pain
Wearable Technological Device Applied to Patients with Chronic Pain
Within the scope of this research, a single session of Wearable Technological Device (Exopulse Molli-Suit) will be applied to patients with chronic back and neck pain.
- Conditions
- Neck Pain, Low Back Pain, Chronic Pain, Musculoskeletal Pain
- Trial name
- NCT06345430
- Testing
- Exopulse Molli-Suit (Wearable Technological Device)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Chronic Pain, Musculoskeletal Pain
National Survey of Chronic Occupational Pain in Thai Anesthesia Providers
The purpose of this nationwide cross-sectional survey is to determine the prevalence, multidimensional impacts, and associated factors of chronic occupational pain among anesthesiologists and nurse anesthetists in Thailand.
- Conditions
- Chronic Pain, Musculoskeletal Pain, Occupational Pain, Occupational Diseases
- Trial name
- NCT07778381
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Fibromyalgia, Neck Pain
Kinesiophobia in Patients With Fibromyalgia Syndrome and Chronic Neck Pain
Kinesiophobia which is described as fear of movement reduces physical activity levels and increases the risk of chronic pain. The investigators consider that kinesiophobia levels are higher in patients with fibromyalgia syndrome…
- Conditions
- Fibromyalgia, Neck Pain, Healthy
- Trial name
- NCT03778801
- Testing
- kinesiophobia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Novel MRI Technique
Functional Evaluation of Brain Pain Centers in Endometriosis-Associated Chronic Pelvic Pain Exploring the Impact of Central Sensitization Using a Novel MRI Technique
Endometriosis is a chronic inflammatory disease characterized by the presence of endometrial tissue outside the uterus, affecting about 10% of reproductive-age women.
- Trial name
- NCT06720181
- Testing
- MRI
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University - Cerrahpasa
Epicondylitis of the Elbow, Servical Segmental Mobilization
Results of Cervical Segmental Mobilization in Patients With Chronic Lateral Epicondylitis
The aim of our study was to investigate the effect of cervical segmental mobilization on pain, functionality, grip strength and quality of life in patients with chronic lateral epicondylitis.
- Trial name
- NCT06440928
- Testing
- mobilization, standard treatment, deep friction
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Halic University
Stable Chronic Angina, Ischemic Heart Disease
Effect of Remote Intervention in Patients With SCAD
The study was a multicenter, two-arm, parallel, open-label, prospective clinical trial that evaluated a remote intervention with 1 year of follow-up.
- Conditions
- Stable Chronic Angina, Ischemic Heart Disease, Coronary Artery Disease, Heart Diseases
- Trial name
- NCT04795492
- Testing
- remote intervention, Routine outpatient follow-up
- Where
- China
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Chronic Pelvic Pain, Myofascial Trigger Point Pain
Effects of Myofascial Release and Electrical Stimulation in Chronic Pelvic Pain
Myofascial pelvic pain (MFPP) caused by myofascial trigger points (MTrPs) is a major contributor to chronic pelvic pain in women.In females,pelvic pain is the single most common indication for referral to women's health…
- Trial name
- NCT05851742
- Testing
- TENS, Myofascial trigger point release
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Complex Regional Pain Syndromes, Chronic Pain
Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up
Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features.
- Trial name
- TORNADO (NCT04597866)
- Testing
- Multimodal rehabilitation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Uppsala University
Chronic Low-back Pain (cLBP), Urinary Incontinence (UI)
Effects of PEMM in Chronic Low Back Pain Women With Urinary Incontinence
Urinary incontinence (UI), Chronic low back pain (CLBP) in women are prevalent and often coexist. Multiple conditions when coexist, it leads to reduced Quality of life in turn causing physical and mental impairment.
- Conditions
- Chronic Low-back Pain (cLBP), Urinary Incontinence (UI), Pelvic External Myofascial Mobilisation, Myofascial Techniques
- Trial name
- NCT07351851
- Testing
- PEMM with Theragun, Active Comparator: Control
- Where
- Qatar
- Volunteers
- 200 people
- Sponsor
- Hamad Medical Corporation
Temporomandibular Disorder
K23- Physical Self Regulation vs Placebo
This study will use a between-person design. Participants will be treatment-seeking patients with chronic masticatory muscle pain.
- Trial name
- NCT06357702
- Testing
- Physical Self Regulation Telehealth, Psycho-education Telehealth
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Ian Boggero, PhD
Leiomyoma, Pelvic Organ Prolapse
The Influence of TAP Block in the Control of Postoperative Pain After Laparotomy for Gynecological Procedures
This study evaluates the influence of the transversus abdominis plane block on the intensity of postoperative pain and the concentration of proinflammatory and pain factors after hysterectomy by laparotomy.
- Conditions
- Leiomyoma, Pelvic Organ Prolapse, Abnormal Uterine Bleeding, Chronic Pain
- Trial name
- TAP (NCT04172272)
- Testing
- Systemic multimodal analgesia administered intravenously, Transversus abdominis plane block (TAP block), Combined transversus abdominis plane block (TAP block) with systemic multimodal analgesia administered intravenously
- Where
- 2 sites in Croatia
- Volunteers
- 75 people
- Sponsor
- General Hospital Pula
Pain, Chronic, Opioid Use Disorder
Pain and Opioid Management in Older Adults
The extent and depth of the ongoing opioid crisis are well known and many interventions are under way in the United States and other countries to alleviate its devastating impact on individuals and the society.
- Trial name
- RISE-OK (NCT05037682)
- Testing
- Dissemination and Implementation Research
- Where
- United States
- Volunteers
- 1,035 people
- Sponsor
- University of Oklahoma
Suprascapular Nerve, Shoulder Impingement Syndrome
The Clinical Efficacy of Different Durations of Suprascapular Nerve Pulsed Radiofrequency
Chronic shoulder pain due to impingement syndrome and supraspinatus tendinosis is a debilitating condition. Suprascapular nerve innervates most part of shoulder joint.
- Conditions
- Suprascapular Nerve, Shoulder Impingement Syndrome, Pulsed Radiofrequency, Chronic Pain
- Trial name
- NCT06713005
- Testing
- suprascapular nerve block and 4 mins Pulsed radiofreuency application to suprascapular nerve, suprascapular nerve block and 9 mins Pulsed radiofreuency application to suprascapular nerve
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara University
Neuropathic Pain, Chronic Pain
Observational Study of the Use of 8% Capsaicin Patch in Children 0 to 18 Years Old
Patients aged less than 18-y with validated 8% capsaicin patch treatment in routine healthcare will be offered to participate the study. If they accept it as well as their parents, they will be included in the study .
- Trial name
- CAPSULE (NCT05299294)
- Testing
- Data collection
- Where
- 20 sites in France
- Volunteers
- 160 people
- Sponsor
- University Hospital, Brest
Facet Joint Pain, Pain Syndrome
Pulsed Radiofrequency Treatment in Lumbar Facet-Related Pain
Facet joint-related pain is one of the leading causes of low back pain. Facet joint-related disorders can have a negative impact on quality of life and daily living activities, in addition to the pain.Conservative treatment…
- Conditions
- Facet Joint Pain, Pain Syndrome, Pain, Chronic
- Trial name
- NCT06157294
- Testing
- Intra-articular pulsed radiofrequency, Median branch pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Knee Pain, Chronic Osteoarthritis
ROSA Total Knee Investigational Testing Authorization Study
This is a prospective, single-center clinical study designed to facilitate the collection and evaluation of workflow efficiency, patient pain and function, and adverse event data.
- Conditions
- Knee Pain, Chronic Osteoarthritis, Avascular Necrosis of Femoral Condyle, Moderate Varus, Valgus or Flexion Deformities
- Trial name
- NCT03970629
- Testing
- PERSONA Total Knee
- Where
- Canada
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Chronic Pain, Opioid Use
Developing and Pilot Testing an Opioid Tapering Protocol
This study proposes to pilot test an intervention to facilitate opioid pain reliever (OPR) tapering in primary care. The intervention will incorporate a clinician embedded within primary care to follow tapering dose schedules to…
- Conditions
- Chronic Pain, Opioid Use, Analgesia
- Trial name
- TapPro (NCT04257695)
- Testing
- TapPro
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Albert Einstein College of Medicine
Inflammatory Bowel Disease, Ulcerative Colitis
Efficacy of Energy Therapy in the Management of Chronic Pain Medical Condition in Children and Adolescents.
Paediatric and adolescent patients with chronic pain associated with their medical condition will be invited to participate in this study.
- Conditions
- Inflammatory Bowel Disease, Ulcerative Colitis, Crohn Disease, Chronic Pancreatitis
- Trial name
- ET&CP (NCT05394272)
- Testing
- Energy Therapy - Pranic Healing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College Hospital NHS Trust
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