Clinical trials: Pain, Chronic Disease
Pain, Breast Cancer
Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy
Prevalence of chronic pain after mastectomy is beyond 50% 3 months after surgery. This pain is related to a sensitization of the central nervous system through N-methyl-D-asparate (NMDA) receptors.
- Trial name
- NCT00129597
- Testing
- ketalar
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Musculoskeletal Pain, Fibromyalgia, Primary
Effectiveness of Virtual Reality (VR) in Non-oncologic Chronic Musculoskeletal Pain
Treatment options for chronic non-oncologic musculoskeletal pain are varied and include both pharmacological and non-pharmacological interventions, such as physical activity and psychotherapy.
- Trial name
- NCT06100926
- Testing
- software
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Azienda Sanitaria-Universitaria Integrata di Udine
Chronic Pain, Complex Regional Pain Syndromes
The Success of Lumbar Sympathetic Ganglion Block Using Lower Extremity Perfusion Index
The patient, who is experiencing chronic pain in the lower extremities persisting for more than three months, is scheduled to undergo lumbar sympathetic ganglion block.
- Conditions
- Chronic Pain, Complex Regional Pain Syndromes, Peripheral Neuropathy, Post Herpetic Neuralgia
- Trial name
- NCT06241820
- Testing
- Lumbar Sympathetic Ganglion Block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jeongsoo Kim
Chronic Neuropathic Pain
Effects of Amitriptyline for the Treatment of Pain on Driving Performance and Cognition.
The acute and subchronic effects of amitriptyline were compared to placebo in a double-blind crossover randomized study on driving ability and driving-related skills in chronic neuropathic pain patients.It was hypothesized that…
- Trial name
- NCT00189059
- Testing
- amitriptyline
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- UMC Utrecht
Persistent Pain, Pain Management
Self-monitoring and Remote Monitoring of Chronic Pain in Primary Care - Using a Digital Tool to Improve Quality of Life
Chronic pain impacts individuals, their families, and society significantly, yet specialist care resources are limited, with most patients managed in primary care.
- Conditions
- Persistent Pain, Pain Management, Remote Monitoring
- Trial name
- NCT07141108
- Testing
- Paindrainer Care system
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University
Fibromyalgia
Remote Gamified Sensory Perceptual Training for Patients With Fibromyalgia: a Feasibility Trial
The purpose of this study is to determine the feasibility of gamified sensory perceptual training in people with fibromyalgia. The primary aim is to determine the feasibility of at-home somatosensorial training for people with…
- Trial name
- NCT04919525
- Testing
- TrainPain
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Multiple Sclerosis
Dry Needling in Multiple Sclerosis
This study is being conducted at the Human Functional Performance Laboratory in the School of Physical Therapy and Rehabilitation Sciences (MDT Building) at the University of South Florida.
- Trial name
- NCT07615725
- Testing
- Dry Needling
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of South Florida
Low Back Pain, Obesity
The Effect of Traction Forces in People With Obesity Suffering From Chronic Low Back Pain
The purpose of the research study is to assess the impact of traction forces on changes in systemic markers concentrations of spinal structure damage in people with obesity.
- Trial name
- NCT04507074
- Testing
- lumbar traction therapy
- Where
- Poland
- Volunteers
- 49 people
- Sponsor
- Poznan University of Physical Education
Long COVID
Exercise for Health in Patients With Post-acute Sequelae of COVID-19
Background: Many patients with COVID-19 present the so-called post-acute sequelae of COVID-19 such as fatigue, post-stress discomfort, dyspnea, headache, pain mental impairment, incapacity to perform daily physical tasks ant…
- Trial name
- EJerSA-COVID (NCT05848518)
- Testing
- Rehabilitation program
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Campus docent Sant Joan de Déu-Universitat de Barcelona
Pancreatitis, Chronic
Prospective Study on Endoscopic Ultrasound (EUS) Celiac Bloc Efficacy in Chronic Pancreatitis
The purpose of this study is to determine if celiac bloc (with injection of steroid and local anesthetic) is superior to a sham procedure for pain control and quality of life improvement in patient with chronic pancreatitis and…
- Trial name
- NCT01318590
- Testing
- EUS procedure with drug injection, EUS procedure
- Where
- 2 sites in Belgium, Canada
- Volunteers
- 2 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Heart Diseases, Heart Failure
Mindfulness & Stress Management Study for Cardiac Patients
The guideline-recommended standard of care for patients who have experienced a heart attack, heart failure, or other coronary event or procedure is exercise-based cardiac rehabilitation (CR).
- Conditions
- Heart Diseases, Heart Failure, Myocardial Infarction, Chronic Stable Angina
- Trial name
- NCT02722213
- Testing
- Mindfulness-Based Stress Reduction (MBSR).
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Minnesota
Chronic Pain
Personalized Treatment by rTMS in Chronic Pain - Study2
Previous research has shown the effectiveness of magnetic stimulation of the brain as a supplemental treatment for various conditions, such as depression and chronic pain.
- Trial name
- PersoNINpain (NCT07247552)
- Testing
- rTMS to M1
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Aalborg University
Radius Fractures, Hand Injuries
Thumb and Wrist Proprioception Exercises.
Distal radius fracture is the most common upper extremity fracture with peak incidence among older women after the fifth decade of life. Proprioception is one constituent of a complex Sensory motor control process.
- Conditions
- Radius Fractures, Hand Injuries, Pain, Chronic, Proprioceptive Disorders
- Trial name
- NCT04930718
- Testing
- Thumb active Exercises
- Where
- Spain
- Volunteers
- 47 people
- Sponsor
- University of Malaga
Severe Mobility Impairment, Spinal Cord Injuries (SCI)
Effects of Virtual Walking on Chronic Pain and Psychological Distress for Individuals With Severe Mobility Impairment
This randomized controlled trial aims to: (1) examine the effects of virtual walking intervention on chronic pain (primary outcome), and on depression, stress, anxiety, and quality of life (secondary outcomes) compared with the…
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (SCI), Poliomyelitis
- Trial name
- NCT07820618
- Testing
- Virtaul walking, Passive observing video
- Where
- Hong Kong
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Chronic Pain, Endometriosis
Return to Work in Patients With Chronic Pain
This study aims to evaluate whether a vocational behaviour change ability programme has any additional effect on return to work compared with return to work coordination only in persons with chronic pain.
- Trial name
- UWORKin (NCT03827174)
- Testing
- Return To Work Coordination, Behaviour Change Ability Program
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Uppsala University
Osteoarthritis, Knee
A Clinical Study to Investigate the Effect on Pain Relief of a Single Dose of JNJ-39439335 in Patients With Chronic Osteoarthritis Pain of the Knee
The purpose of this single-center study is to evaluate the potential analgesic effects of a single oral dose (50 mg) of JNJ-39439335, an investigational drug being developed for the treatment of pain in patients with chronic…
- Trial name
- NCT00933582
- Volunteers
- 33 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Musculoskeletal Manipulations
Effects of Myofascial Release and TENS Over Pain, Hand Prehensile Strength and Functionality of Superior Extremity in Women With Lateral Epicondylalgia
This study evaluated the additive effect of myofascial release therapy on the brachial biceps on conventional management (TENS) in pain intensity, hand prehensile strength and upper limb functionality of individuals with lateral…
- Trial name
- NCT04023279
- Testing
- TENS, Myofascial therapy
- Where
- Chile
- Volunteers
- 32 people
- Sponsor
- Fernanda Merino Alvarez
Chronic Pain, Osteoarthritis
Effects of tDCS and tUS on Pain Perception in OA of the Knee
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) in conjunction with transcranial ultrasound (TUS) on pain perception and functional limitations in people with…
- Trial name
- NCT02330315
- Testing
- transcranial direct current stimulation (tDCS), transcranial ultrasound (TUS)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Spaulding Rehabilitation Hospital
Osteoarthritis, Rheumatoid Arthritis
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
The purpose of this study is to evaluate the safety of long-term treatment with HZT-501, a fixed-dose combination oral tablet of 800 mg ibuprofen and 26.6 mg famotidine for patients that require long-term NSAID treatment.
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Chronic Low Back Pain, Chronic Regional Pain Syndrome
- Trial name
- NCT00984815
- Testing
- HZT-501
- Where
- 4 sites in United States
- Volunteers
- 86 people
- Sponsor
- Amgen
Breast Cancer, Chronic Pain
Effect of Perioperative CBT on Chronic Persistent Postsurgical Pain Among Breast Cancer Patients
Chronic persistent post-surgical pain (CPSP) is defined as pain at or near the site of surgery persisting for 3 months or more after the date of surgery.
- Conditions
- Breast Cancer, Chronic Pain, Chronic Postsurgical Pain, Quality of Life
- Trial name
- NCT04924010
- Testing
- Cognitive Behavioural Therapy (CBT), Education and Mindfulness
- Where
- Ireland
- Volunteers
- 48 people
- Sponsor
- Mater Misericordiae University Hospital
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