Clinical trials: Pain, Chronic Disease
Spinal Cord Injuries
TENS Trial to Prevent Neuropathic Pain in SCI
The purpose of this research study is to: 1) test whether transcutaneous electrical nerve stimulation (TENS) after spinal cord injury can reduce the onset of post-injury neuropathic pain; and 2) to learn more about this kind of…
- Trial name
- TENS (NCT03267810)
- Testing
- TENS
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Endometriosis
Improving Access to Pelvic Health Physiotherapy for Endometriosis
This is a mixed-methods study aimed to generate new evidence to help optimize access to pelvic health physiotherapy (PHPT) for women living with endometriosis in the province of Quebec (Canada).
- Trial name
- ENDO-RM (NCT07731776)
- Where
- Canada
- Volunteers
- 264 people
- Sponsor
- Université de Sherbrooke
Acute Myocardial Infarction, Stable Angina
Development and Efficacy Evaluation of Integrated Chronic Care and Health Promotion Model for Patients With Coronary Artery Disease in Taiwan
The hypothesis of this project is to examine whether the integrated health care program as the intervention group can reduce the recurrence and mortality of coronary artery-related diseases than the traditional one as the…
- Trial name
- NCT01357096
- Testing
- Integrated health care team, Traditional group
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Neck Pain, Chronic Pain
Trial Outcomes for Massage: Caregiver-Assisted vs. Therapist-Treated
Given the modest effectiveness of current treatments and the burden chronic neck pain places on Veterans, the investigators' research proposal is significant in several regards.
- Conditions
- Neck Pain, Chronic Pain, Pain, Arthritis
- Trial name
- TOMCATT (NCT03100539)
- Testing
- Therapist treated massage, Care ally assisted massage
- Where
- United States
- Volunteers
- 395 people
- Sponsor
- VA Office of Research and Development
Knee Osteoarthritis, Chronic Knee Pain
Selective Nerve Ablation for Chronic Knee Pain: A Retrospective Study
SAVE-KNEE is a single-center retrospective observational cohort study evaluating outcomes of ultrasound-guided cryoneurolysis, radiofrequency ablation and chemical neurolysis for chronic knee pain in routine clinical care.
- Trial name
- SAVE-KNEE (NCT07835672)
- Testing
- Ultrasound-Guided Cryoneurolysis, Ultrasound-Guided Radiofrequency Ablation, Ultrasound-Guided Chemical Neurolysis
- Where
- Poland
- Volunteers
- 746 people
- Sponsor
- Michał Bartoszewicz
Low Back Pain, Chronic Pain
Aging, Mobility and Chronic Low Back Pain
Chronic low back pain (CLBP) is very common in older adults and is one of the most common reasons for disability and poor quality of life.
- Trial name
- "Chronic pain" (NCT05167877)
- Testing
- No intervention will be given to the participants
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- McMaster University
Pain, Chronic, Whiplash Injury
Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash
With the present study the investigators wish to examine if reconceptualisation of pain, by educating chronic whiplash-associated disorders (CWAD) patients on the neurophysiology of pain, in combination with psychologic…
- Trial name
- NCT01544075
- Testing
- Pain neurophysiology education (PNE) and psychologic inoculation (PI), Neck school (NS)
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Vrije Universiteit Brussel
Perinatal Depression, Chronic Pain
CSF/Serum Biomarkers in Predicting PND/Persistent Pain After Cesarean
The aim is to investigate if inflammatory biomarkers in the blood and cerebrospinal fluid (CSF) are associated with the development of perinatal depression and/or persistent pain after cesarean delivery.
- Trial name
- NCT04271072
- Testing
- No intervention
- Where
- United States
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Duke University
Musculoskeletal Pain
Enhanced Biofeedback for Musculoskeletal Pain
The purpose of this study is to assess whether a novel, enhanced form of biofeedback can help individuals regulate their chronic musculoskeletal pain more effectively.
- Trial name
- NCT02920853
- Testing
- Biofeedback Training (BT-CPR), Biofeedback Training
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Tulsa
Pain, Chronic, Osteoarthritis, Knee
Effects of Action Observation Therapy on Pain, Functional Level and Brain Hemodynamic in Patients With Knee Osteoarthritis
In this project, investigators aim to investigate the effects of action observation therapy on pain, fear of movement, functional level and brain hemodynamics in patients with knee osteoarthritis.
- Trial name
- NCT03245073
- Testing
- Action observation therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Acibadem University
Back Pain Lower Back Chronic
Effectiveness of a Psychoeducative Intervention on Patients With Cronic Low Back Pain
One of the treatment modalities currently available in this hospital to treat this type of patients with low back pain who present with chronic pain are the group sessions that are carried out to provide information to the…
- Trial name
- PNE (NCT03964389)
- Testing
- Pain Neuroscience Education" (PNE)
- Where
- Spain
- Volunteers
- 179 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Chronic Neck Pain
Determines of Quality of Life in Patients
Pain, muscle spasm, loss of muscle strength and impaired posture adversely affect the daily life activities and quality of life of neck pain patients.However, the quality of life; It is a multifaceted concept that includes not…
- Trial name
- NCT04201379
- Testing
- quality of life assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Baskent University
Chronic Opioid Use
VA Transitional Pain Service Study
The VA Community Care Program has provided an important resource to improve access to surgical care for Veterans unable to have treatment at VA Medical Centers (VAMC).
- Trial name
- VATPS (NCT06223503)
- Testing
- Transitional Pain Service
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- VA Office of Research and Development
Fibromyalgia
Online Mindfulness Training Versus Health Education for Fibromyalgia
The purpose of this study is to compare an online 12-module intervention designed to improve emotion regulation and social relations via mindfulness training with a 12-module program that provides information about health…
- Trial name
- EGIFT (NCT01748786)
- Testing
- Mindfulness Emotion Regulation, Health Education
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Arizona State University
Chronic Low Back Pain, Degenerative Disc Disease
Intra-discal Injection of Platelet-rich Plasma (PRP) Enriched With Exosomes in Chronic Low Back Pain
Intervertebral disc pathology accounts for 40% or more cases of chronic LBP. Available treatment options do not improve the underlying degenerative condition hence This indicates the need for new therapies.
- Trial name
- NCT04849429
- Testing
- Platelet rich plasma (PRP) with exosomes, Normal Saline
- Where
- 2 sites in India
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Dr. Himanshu Bansal Foundation
Knee Pain Chronic, Osteoarthritis
Persona Total Knee Arthroplasty Outcomes Study
The primary objective of this study is to obtain implant survivorship and clinical outcomes data for commercially available Persona fixed bearing knee implants used in total knee arthroplasty.
- Conditions
- Knee Pain Chronic, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis
- Trial name
- NCT02255383
- Testing
- Zimmer Persona Total Knee System
- Where
- 14 sites in United States
- Volunteers
- 737 people
- Sponsor
- Zimmer Biomet
Hyperalgesia, Pain
Local Anesthetic Infusion and Sternotomy
Cardiac surgery often induces acute postoperative pain and moreover chronic dysesthesia frequently occur long-term after sternotomy.
- Trial name
- CARDIODOLAL (NCT00802048)
- Testing
- Local anesthetic (Ropivacaine), Saline
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Interstitial Cystitis, Chronic Prostatitis
Chronic Pelvic Pain Study of Individuals With Diagnoses or Symptoms of Interstitial Cystitis and/ or Chronic Prostatitis
The Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network has been established to focus on a broader approach to the study of Interstitial Cystitis (IC)/Painful Bladder Syndrome (PBS) in men and…
- Trial name
- MAPP-EP (NCT01098279)
- Where
- 8 sites in United States
- Volunteers
- 424 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Fibromyalgia (FM)
Interdisciplinary Program to Improve Quality of Life in People With Fibromyalgia
Fibromyalgia is a chronic condition characterized by widespread pain, fatigue, sleep disturbances, and psychological symptoms that significantly affect quality of life.
- Trial name
- NCT07661745
- Testing
- FIBROCatCentral Multidisciplinary Intervention Program
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Tendinopathy
ESWT vs Cryo-US Therapy in the Treatment of Chronic Lateral Epicondylitis: One Year Follow up Study
Chronic lateral epicondylitis is usually managed conservatively. The purpose of this single-blinded, randomized, controlled study is to compare the clinical therapeutic effects of extracorporeal shock wave therapy (ESWT) in…
- Trial name
- NCT02371902
- Testing
- MODULITH® SLK, STORZ MEDICAL AG, Switzerland, Cryoultrasound™, Medisport S.r.l., Italy
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- University of Roma La Sapienza
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