Clinical trials: Pain, Chronic Disease
Chronic Pain, Pain
Effectiveness of a Pain Science Education Programme in Adolescent Students.
The aim of this study is to analyze the effectiveness of a Pain Science Education program to improve the conceptualization of pain in adolescents between 11 and 13 years old, schooled in the first year of Compulsory Secondary…
- Conditions
- Chronic Pain, Pain, Pediatric ALL
- Trial name
- EDEA (NCT06060431)
- Testing
- Pain Science Education
- Where
- Spain
- Volunteers
- 293 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
PTSD, Chronic Pain
Preventing the Development of Chronic Pain: Treating PTSD at Acute Pain Onset
Although most people recover from acute pain (such as pain caused by injury, surgery, repetitive motion, or unknown causes), many people do not fully recover and will experience chronic pain.
- Trial name
- NCT05700279
- Testing
- Stellate Ganglion Block, Cognitive Processing Therapy
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- Rush University Medical Center
Surface and Deep Dyspareunia
Physiotherapeutic Approach to Superficial and Deep Dyspareunia in Women With Chronic Pelvic Pain: Comparison Between In-person and Telehealth Care.
Adequate sexual function is considered an important factor in satisfaction and overall quality of life for both men and women. It is estimated 16% to 40% of women suffer from some form of sexual dysfunction, which is currently…
- Trial name
- NCT07658703
- Testing
- Face-to-face treatment, Telecare
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Sao Paulo
Chronic Low Back Pain (CLBP)
Art Therapy for Adults With Chronic Low Back Pain
This project aims to assess the feasibility and preliminary efficacy of a supervised group-based art intervention for adults with chronic low back pain (CLBP).
- Trial name
- NCT07141069
- Testing
- Art therapy combined with Exercise, Exercise
- Where
- 2 sites in Hong Kong
- Volunteers
- 30 people
- Sponsor
- The Hong Kong Polytechnic University
Overweight or Obesity, Chronic Low-back Pain
Lifestyle Intervention in Overweight/Obese Chronic Low Back Pain (CLBP) Patients: an International Multi-center RCT
Chronic low back pain (CLBP) is the most expensive cause of workrelated disability: it causes the highest number of years lived with disability.
- Trial name
- BO2WL (NCT05811624)
- Testing
- Physiotherapy intervention, including behavioral weight reduction program combined with pain neuroscience education and cognition-targeted exercise therapy., Physiotherapy intervention, including pain neuroscience education and cognition-targeted exercise therapy alone.
- Where
- 2 sites in Belgium, Switzerland
- Volunteers
- 252 people
- Sponsor
- Vrije Universiteit Brussel
Spondylosis Lumbar
Battlefield Acupuncture as an Adjunct to Electroacupuncture for Chronic Low Back Pain Due to Lumbar Spine Osteoarthritis
Chronic low back pain due to lumbar spine osteoarthritis is a common and disabling condition. Many patients do not get enough relief from standard treatments.
- Trial name
- NCT06874959
- Testing
- Battlefield Acupuncture (BFA), Electroacupuncture, Paracetamol 500 mg (as-needed)
- Where
- 2 sites in Vietnam
- Volunteers
- 60 people
- Sponsor
- Bui Pham Minh Man
Chronic Pelvic Pain
The Effect of Jincaopian Tablets on Chronic Pelvic Pain After Pelvic Inflammatory Disease
This phase II trial attempts to evaluate the efficacy and safety of Jincaopian Tablets in the treatment of subjects with chronic pelvic pain after pelvic inflammatory disease.
- Trial name
- NCT05460546
- Testing
- Jincaopian Tablets high dose, Jincaopian Tablets low dose
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Beijing Konruns Pharmaceutical Co., Ltd.
Chronic Venous Insufficiency, CVI
Respiratory Functions, Aerobic Capacity and Quality of Life in Chronic Venous Insufficiency
This study aims to retrospectively examine the dataset obtained from a previously conducted study titled 'Inspiratory muscle training in individuals with chronic venous insufficiency: randomized controlled trial'.
- Trial name
- NCT06785805
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Izmir Democracy University
Sickle Cell Disease
Imatinib for Pain in Sickle Cell Anemia
In this protocol, the investigators propose to evaluate the biochemical effects of imatinib on sickle red blood cells (RBCs). Patients will be administered imatinib mesylate orally following the guidelines previously established…
- Trial name
- IMPACT (NCT03997903)
- Testing
- Imatinib Mesylate
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Indiana University
Urology, Urological Diseases
RUTISS-Diary and RUTISS-65 Study
Existing patient-reported outcome measures assess acute urinary tract infection but do not support daily symptom tracking in recurrent UTI (rUTI) or meet the needs of older adults.
- Conditions
- Urology, Urological Diseases, Patient Satisfaction, Pain, Chronic
- Trial name
- NCT07698041
- Testing
- Non-interventional Patient Reported Outcome Measure Development (RUTISS-Diary), Non-interventional Patient Reported Outcome Measure Development (RUTISS-65)
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Katherine Finlay
Substance Abuse, Chronic Pain
Physician Coaching to Reduce Opioid-related Harms
This project pilot tests an innovative clinical guideline translation and physician coaching model to promote adherence to evidence-based guidelines for the prescribing of opioid pain medications in primary care settings.
- Trial name
- NCT02433496
- Testing
- Physician coaching
- Where
- United States
- Volunteers
- 53,132 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Opioid-induced Constipation
A Study of Naldemedine (S-297995) for the Treatment of Opioid-Induced Constipation in Adults With Non-Malignant Chronic Pain Receiving Opioid Therapy
The purpose of this study is to determine efficacy and safety of naldemedine for the treatment of opioid-induced constipation in adults with non-malignant chronic pain receiving opioid therapy for ≥ 3 months.
- Trial name
- NCT01443403
- Testing
- Naldemedine
- Where
- 49 sites in United States
- Volunteers
- 244 people
- Sponsor
- Shionogi
Chronic Headache
Project CHEER (Comprehensive Headache Evaluation, Education, Relief)
PROJECT CHEER is a randomized controlled trial designed to test the effectiveness of a comprehensive focused approach to headache care.
- Trial name
- NCT00417742
- Testing
- Service delivery through a Headache Management Program
- Where
- 3 sites in United States
- Volunteers
- 828 people
- Sponsor
- Duke University
Fibromyalgia
Fecal Microbiome Transplantation From Healthy Donors to Individuals With Fibromyalgia
This study aims to investigate if a fecal microbiome transplantation (FMT) from healthy donors can reduce symptoms of fibromyalgia, a condition causing chronic pain that is difficult to treat and diagnose.
- Trial name
- FM-FMT-RCT (NCT06424041)
- Testing
- Fecal Microbiome Transplantation
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rambam Health Care Campus
Chronic Pain, Depression
Resilience and Well-Being Pilot Study
It is common for Veterans with injuries, illnesses, or physical disabilities to experience depression, post-traumatic stress disorder (PTSD), chronic pain, and other concerns.
- Conditions
- Chronic Pain, Depression, PTSD, Injuries
- Trial name
- NCT03563820
- Testing
- Resilience and Well-Being Program
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- VA Puget Sound Health Care System
Knee Osteoarthritis, Chronic Pain
Neurophysiological Mechanisms Involved in Knee Osteoarthritis
Introduction: Total knee arthroplasty (TKA) is an effective intervention to relieve people with osteoarthritis (OA). Nevertheless, 15 to 30% of patients continue to experience severe pain following surgery.
- Trial name
- NCT03556423
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Université de Sherbrooke
Low Back Pain
Device-Based vs Manual Sensory Training in Low Back Pain
Chronic low back pain (CLBP) is a leading cause of disability worldwide and affects a large proportion of working-age individuals.
- Trial name
- NCT07277803
- Testing
- Technology-Based Sensory Acuity Training Group (T-SATG), Control Group (CG), Manual Sensory Acuity Training Group (M-SATG)
- Volunteers
- 66 people
- Sponsor
- Medipol University
Low Back Pain
Efficacy and Safety of Lymphdiaral Basistropfen (HDC) in the Treatment of Chronic Low-back Pain
To evaluate superiority of HDC in comparison to placebo in the treatment of chronic low-back pain in relation to pain, functional impairment, quality of life, and state of health during a 15-week treatment period.
- Trial name
- 144 (NCT01049373)
- Testing
- HDC
- Where
- Germany
- Volunteers
- 221 people
- Sponsor
- Pascoe Pharmazeutische Praeparate GmbH
Chronic Refractory Plantar Fasciopathy
Multimodal Conservative Intervention Versus Surgery for Chronic Refractory Plantar Fasciopathy
Chronic refractory plantar fasciopathy is a common musculoskeletal condition that can cause persistent heel pain and functional limitations despite conservative treatment.
- Trial name
- NCT07654660
- Testing
- Multimodal Conservative Intervention, Endoscopic Plantar Fascial Release
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universidad Europea de Valencia
Chronic Pain
ElderTree Smart System for Older Adults
Multiple chronic conditions (MCCs) are costly and pervasive among older adults. MCCs account for 90% of Medicare spending, and 65% of Medicare beneficiaries have 3 or more chronic conditions; 23% have 5 or more.
- Trial name
- NCT04798196
- Testing
- ElderTree on laptop (ET- LT), ElderTree on smart system (ET- SS), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 268 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
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