Clinical trials: Pain, Chronic Disease
Ehlers-Danlos Syndrome, Pain
Mind-Body Therapy for Pain in Ehlers-Danlos Syndrome
This study will assess the effectiveness of mind-body therapy in relieving pain in patients with Ehlers-Danlos syndrome. This syndrome is a hereditary condition caused by a connective tissue defect and is often associated with…
- Trial name
- NCT00001966
- Testing
- Mind-body therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
Chronic Pain, Mental Disorder
Early Detection of Mental Disorders in Adolescents With Chronic Pain: Creation of a Screening Tool for Use by the General Practitioner
This research aims to create a tool for detection of mental health disorders in adolescents with chronic pain. The first part is testing a screening questionnaire and comparing in with existing questionnaires.
- Trial name
- REPERADO (NCT04467229)
- Testing
- Focus group
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pes Planus, Flatfoot
Central Sensitization and Nociplastic Pain in Pes Planus
Background: Pes planus, commonly known as flatfoot, is a condition characterized by the collapse of the medial longitudinal arch of the foot.
- Conditions
- Pes Planus, Flatfoot, Central Sensitization, Nociplastic Pain
- Trial name
- NCT07125781
- Where
- Turkey (Türkiye)
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Bozok University
Chronic Pain, Carpal Tunnel Syndrome
Dexmedetomidine Versus Triamcinolone Treatment of Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is a common mononeuropathy due to entrapment of the median nerve in the carpal tunnel. a lot of modaleties are available for treatment of mild to moderate CTS.
- Trial name
- NCT04961281
- Testing
- Dexmedetomidine, Triamcinolone
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Postoperative Pain, Video-assisted Thoracoscopic Surgery
ESP Block, CNP and QoL After VATS
The Erector Spinae Plane Block (ESPB) is an adequate alternative for pain management after video-assisted thoracoscopy surgery (VATS).
- Trial name
- NCT04737902
- Testing
- Erector spinae plane block
- Where
- Colombia
- Volunteers
- 42 people
- Sponsor
- Hospital Universitario San Ignacio
Chronic, Infection
Pulpectomy of Primary Molars With Rotary Instrumentation Versus Manual Instrumentation
One of the major concerns in pediatric dentistry is premature loss of necrotic primary teeth which may cause a deleterious effect on the growth of the facial skeletal complex.
- Trial name
- NCT03964766
- Testing
- Rotary instrumentation, Hand instrumentation
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pain
Manage My Pain at Chronic Pain Clinics
The overall objective of this Early Adoption project is to gather evidence for how Managing My Pain Program (MMP), a novel digital pain management application can enable better care at home for chronic pain sufferers in the…
- Trial name
- NCT04762329
- Testing
- Manage My Pain (MMP) digital pain app group
- Where
- Canada
- Volunteers
- 246 people
- Sponsor
- University Health Network, Toronto
Chronic Low-back Pain, Hallux Rigidus
Foot Spine Syndrome "RAFFET Syndrome"
case series aimed to describe a new clinical condition for the first time in the medical literature called Foot Spine Syndrome or "RAFFET Syndrome".
- Trial name
- NCT06180408
- Testing
- manual therapy and exercise for the big toe, lumbar stabilization exercise
- Where
- Egypt
- Volunteers
- 11 people
- Sponsor
- Noha Khaled Shoukry
Plantar Fasciitis, Chronic
A Novel Approach to Plantar Fasciitis in the Aging Population
The goal of this study is to determine whether improving foot strength through foot exercises and minimal footwear can provide improved outcomes over the short and long term.
- Trial name
- NAPA (NCT05834491)
- Testing
- minimal shoes and foot strengthening and flexibility exercises, Supportive Footwear, foot orthotic device and foot flexibility exercises
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- University of South Florida
Chronic Pain
Chronic Pain Management After Herniorraphy
Nowadays, chronic pain mainly as a result of iatrogenic nerve damage is generally considered as the most frequent complication after inguinal hernia surgery.
- Trial name
- pregabalin (NCT00772291)
- Testing
- pregabalin
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Erasmus Medical Center
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Multiple Sclerosis, Chronic Pain
Virtual Reality (VR) to Improve Quality of Life in Patients Diagnosed With Neurological Disorders
Participants with neurological disorders will be recruited to complete sessions of virtual reality (VR) immersion. VR has been shown to have therapeutic benefit in certain patient populations and requires further clinical study…
- Conditions
- Multiple Sclerosis, Chronic Pain, Neurological Disorder
- Trial name
- NCT03606668
- Testing
- HTC Vive Virtual Reality (VR) system
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- NYU Langone Health
Osteoarthritis, Knee
A Clinical Study to Test Efficacy and Safety of Repeat Doses of CNTX-4975-05 in Patients With Osteoarthritis Knee Pain
This is a randomized, double-blind, placebo-controlled, 2-injection, 52-week study to evaluate the efficacy and safety of intra-articular injections of CNTX-4975-05 in subjects with chronic, moderate-to-severe osteoarthritis knee…
- Trial name
- NCT03660943
- Testing
- CNTX-4975-05
- Where
- 30 sites in United States
- Volunteers
- 332 people
- Sponsor
- Centrexion Therapeutics
Prostatitis
Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis
The purpose of this study is to determine whether tamsulosin and tolterodine are effective in the treatment of men with lower urinary tract symptoms and chronic prostatitis/chronic pelvic pain syndrome.
- Trial name
- ESTTFCP (NCT00913315)
- Testing
- tolterodine, tamsulosin
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chongqing Medical University
TMD
Pain Neuroscience Education, Motor Imagery and Action Observation in Patients With Chronic Temporomandibular Disorders.
The objective of this study will be to verify the additional effect of Pain Neuroscience Education, Motor Imagery and Action Observation on primary outcomes pain intensity and craniofacial pain and disability in patients with…
- Trial name
- NCT05003349
- Testing
- Occlusal Splint (OS)., Pain Neuroscience Education (PNE)., Motor Imagery (MI).
- Where
- Argentina
- Volunteers
- 50 people
- Sponsor
- University of Gran Rosario
Chronic Pain, Anxiety
Music Intervention in Chronic Pain Patients
The goal of this randomized controlled trial is to evaluate the efficacy of a personalized music intervention program to improve the condition of individuals suffering from chronic pain.
- Conditions
- Chronic Pain, Anxiety, Well-Being, Psychological
- Trial name
- MusicCPP (NCT06436378)
- Testing
- Music intervention in person
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Laval University
Breast Cancer
Investigation of the Efficiency of Pain Neuroscience Education in Patients With Chronic Pain After Breast Cancer Surgery
Breast cancer is the most common type of cancer among women worldwide. Various side effects are seen after the treatments (surgery, chemotherapy, radiotherapy, etc.).
- Trial name
- NCT06052085
- Testing
- Pain Neuroscience Education, Biomedical Pain Education, Standard Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Hacettepe University
Opioid Dependence, Chronic Pain
Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery
The goal of this study is to determine whether comprehensive perioperative administration of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine can increase postoperative pain tolerance and reduce opiate consumption in…
- Trial name
- NCT04220489
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Jacques E. Chelly
Chronic Pain, Rheumatoid Arthritis
Effects of Virtual Reality on Brain Hemodynamic Activity in Chronic Pain
Virtual reality systems have been applied in recent years to reduce pain intensity and fear of movement in individuals with acute and chronic pain.
- Conditions
- Chronic Pain, Rheumatoid Arthritis, Virtual Reality
- Trial name
- NCT06154850
- Testing
- Immersive virtual reality, Non-immersive virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Acibadem University
Chronic Low-back Pain
MIC of Turkish Pain-related Psychological Measures
This study evaluates the responsiveness and minimal important change of the Turkish versions of the Fear-Avoidance Beliefs Questionnaire, Tampa Scale for Kinesiophobia, and Pain Catastrophizing Scale in adults with chronic…
- Trial name
- NCT06271447
- Testing
- Standardized Rehabilitation Program
- Where
- Turkey (Türkiye)
- Volunteers
- 124 people
- Sponsor
- Acibadem University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.