Clinical trials: Pain, Chronic Disease
Fibromyalgia, Chronic Pain
Efficacy of Psychological Therapy in Chronic Pain and Fibromyalgia
Today, one of the most important challenges of the health system is the attitude towards chronic disorders. That implies changing from a health structure established for the treatment of acute diseases to a continued care system.
- Trial name
- DOLORTRATPSI (NCT03992612)
- Testing
- control group: usual medical care, MBPM- Mindfulness-Based Pain Management
- Where
- Spain
- Volunteers
- 112 people
- Sponsor
- University of the Basque Country (UPV/EHU)
Headache
Acceptance and Commitment Therapy vs Medical Treatment as Usual Wait-list Control for Primary Headache Sufferers
Research to date suggests that individuals with headache use avoidance as a way to manage their pain. Despite the wide use of avoidance as a coping mechanism of headache triggers, very little empirical evidence exist to support…
- Trial name
- ALGEA (NCT02734992)
- Testing
- ACT+ MTAU, Waitlist Control +MTAU
- Where
- Cyprus
- Volunteers
- 100 people
- Sponsor
- University of Cyprus
Chronic Low-back Pain
Interferential Current Treatment Reduces Low Back Pain and Improves Functionality in Patients With Chronic Low Back Pain.
. 24 individuals were evaluated, with low back pain for more than 12 weeks and aged between 12 and 65 years. The current used in the lumbar region of the participants was of the tetrapolar interferential type and the stimulation…
- Trial name
- NCT05843136
- Testing
- physiotherapy treatment
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Universidade Federal do Oeste do Para
Chronic Pain, Tobacco Use
Opioids, Low Nicotine Cigarettes, and Chronic Pain
The purpose of this study is to evaluate the effects of switching to very low nicotine content (VLNC) cigarettes versus normal nicotine content (NNC) cigarettes on craving, withdrawal, and pain among individuals with chronic pain…
- Conditions
- Chronic Pain, Tobacco Use, Opioid Substitution Treatment
- Trial name
- NCT06747871
- Testing
- Very Low Nicotine Cigarettes (VLNC), Normal Nicotine Cigarettes (NNC)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Duke University
Pain, Chronic, Urge Incontinence
Using Oral Valacyclovir to Treat Patients With Refractory IC/BPS
Interstitial cystitis/bladder pain syndrome (IC/BPS) is a collective term referring to disorders which is characterized by lower urinary tract symptoms, including bladder pain/discomfort, frequent urination without evidence of…
- Conditions
- Pain, Chronic, Urge Incontinence, Overactive Bladder Syndrome, Quality of Life
- Trial name
- VARIC (NCT05094414)
- Testing
- Valacyclovir
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Pelvic Pain, Abdominal Pain
Female Chronic Pelvic Pain
The purpose of this study is to investigate the frequency and severity of chronic pelvic pain (CPP) in adult women living in Copenhagen Country and Zealand Country (total population 2,4 million), Denmark, in relation to selected…
- Conditions
- Pelvic Pain, Abdominal Pain, Painful Bladder Syndrome, Interstitial Cystitis
- Trial name
- Female CPP (NCT01255345)
- Testing
- Chronic pelvic pain
- Where
- Denmark
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital at Herlev
Breast Cancer, Pain
Psychological and Social Factors and Risk Chronic Pain After Surgery in Women With Breast Cancer
Certain psychological and social factors may increase the risk of developing chronic pain after surgery. Evaluating these factors over time in patients who have undergone surgery for breast cancer may help doctors plan treatment…
- Conditions
- Breast Cancer, Pain, Psychosocial Effects of Cancer and Its Treatment
- Trial name
- SDPM (NCT00466830)
- Testing
- questionnaire administration, management of therapy complications, psychosocial assessment and care
- Sponsor
- Institut Bergonié
Episodic Cluster Headache, Chronic Cluster Headache
A Study of LY2951742 (Galcanezumab) in Participants With Cluster Headache
The main purpose of this study is to assess the long-term safety and tolerability of galcanezumab administered up to once monthly in participants with episodic or chronic cluster headache who have completed study I5Q-MC-CGAL…
- Trial name
- NCT02797951
- Testing
- Galcanezumab
- Where
- 40 sites in United States, Belgium and 10 more
- Volunteers
- 165 people
- Sponsor
- Eli Lilly and Company
Cerebral Palsy, Chronic Post Surgical Pain
Chronic Postsurgical Pain
The study purpose is to document the typical trajectory of perioperative pain experience in Cerebral Palsy (CP) and to identify important predictive factors for the development of chronic postsurgical pain.
- Trial name
- CPSP (NCT05764681)
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- Chantel Burkitt
Pain, Constipation
A Study to Demonstrate Improvement in Symptoms of Constipation in Subjects That Require Around-the-clock Opioid Pain Killer Therapy
The primary research objective is to demonstrate that subjects taking OXN PR have improvement in symptoms of constipation as measured by the Bowel Function Index (BFI) compared to subjects taking OxyPR tablets alone with cancer…
- Trial name
- NCT01438567
- Testing
- oxycodone/naloxone prolonged release (OXN PR) tablets, oxycodone prolonged release (OxyPR) tablets
- Where
- United Kingdom
- Volunteers
- 270 people
- Sponsor
- Mundipharma Research GmbH & Co KG
Chronic Migraine, Headache, Temporomandibular Joint Dysfunction
The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine
The aim of this clinical study to evaluate the effect of temporomandibular joint dysfunction accompanying patients with chronic migraine on pain, quality of life, sleep and functionality.
- Conditions
- Chronic Migraine, Headache, Temporomandibular Joint Dysfunction, Chronic Pain, Quality of Life
- Trial name
- NCT05381129
- Testing
- Detection of Pain, Quality of Life, Sleep and Functioning, Temporomandibular joint dysfunction
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul University - Cerrahpasa
Rheumatoid Arthritis
Cognitive-Behavioral Therapy and Tai Chi Chih for Patients With Rheumatoid Arthritis
Rheumatoid arthritis (RA) is a chronic illness. Patients with RA often experience significant pain and depression. This study will evaluate two programs designed to improve the symptoms of RA: cognitive-behavioral therapy (CBT)…
- Trial name
- NCT00072657
- Testing
- Cognitive Behavioral Therapy, Tai Chi Chih, Health Education Seminar
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of California, Los Angeles
Hemophilia, Chronic Pain
Multimodal Telerehabilitation Versus Face-to-Face Care for Adults With Hemophilia and Chronic Pain
Hemophilia is an inherited bleeding disorder that is commonly associated with chronic joint pain, reduced physical function, and decreased quality of life.
- Trial name
- HEMO-TELE (NCT07682519)
- Testing
- other, Exercise
- Where
- Chile
- Volunteers
- 24 people
- Sponsor
- University of Chile
Angina (Stable), Coronary Occlusion
Drug-Coated Balloon Only Strategy After Recanalization of Chronic Total Coronary Occlusions
Chronic total occlusions (CTO) of the coronary arteries are usually treated with drug-eluting stents (DES) after successful recanalization.
- Conditions
- Angina (Stable), Coronary Occlusion, Coronary Artery Disease, Chronic Total Occlusion
- Trial name
- NoTrace-CTO (NCT07817719)
- Testing
- Paclitaxel-coated balloon (AGENT Paclitaxel-Coated PTCA Balloon Catheter), Serial intravascular ultrasound and protocol-mandated nine-month angiographic reassessment
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Fibromyalgia
Microcurrent for Fibromyalgia
Explore the use of microcurrent therapy for fibromyalgia patients and evaluate its effect on generalized pain and quality of life.
- Trial name
- NCT04949100
- Testing
- Microcurrent Transcutaneous Electrical Nerve Stimulator (TENS) for pain relief
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Paul Crawford
Osteoarthritis, Knee Osteoarthritis
Pain Management In Knee Osteoarthritis
In this study, it was aimed to investigate the effect of pain management education in individuals with knee osteoarthritis with chronic pain.
- Conditions
- Osteoarthritis, Knee Osteoarthritis, Pain, Chronic
- Trial name
- NCT05844319
- Testing
- tele-education
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Istanbul University
Chronic Pain, Neuralgia
Acupuncture Versus Conventional Treatment for Chronic Pain in Patients With Chronic Kidney Disease
This study evaluated acupuncture plus optimized conventional pharmacological treatment compared with optimized conventional pharmacological treatment alone for chronic pain in adults with chronic kidney disease receiving…
- Conditions
- Chronic Pain, Neuralgia, Renal Insufficiency,Chronic
- Trial name
- NCT07891819
- Testing
- Acupuncture, Optimized conventional pharmacological treatment
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of São Paulo
Pain, Chronic, Whiplash Injury
Efficacy of Pain Neurophysiology Education in Combination With Psychologic Inoculation in Chronic Whiplash
With the present study the investigators wish to examine if reconceptualisation of pain, by educating chronic whiplash-associated disorders (CWAD) patients on the neurophysiology of pain, in combination with psychologic…
- Trial name
- NCT01544075
- Testing
- Pain neurophysiology education (PNE) and psychologic inoculation (PI), Neck school (NS)
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Vrije Universiteit Brussel
Chronic Pain, Chronic Lower Back Pain
Project Relief: Developing Brain Stimulation as a Treatment for Chronic Pain
Effective control of chronic pain is a top priority in the United States, as approximately 10% of adults have severe chronic pain most of which is chronic lower back pain (CLBP).
- Conditions
- Chronic Pain, Chronic Lower Back Pain, Back Pain, Opioid Use
- Trial name
- NCT04156802
- Testing
- Real TBS to the mPFC, Real TBS to the MC
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Wake Forest University Health Sciences
Postoperative Delirium, Postoperative Cognitive Dysfunction
The Impact of Repetitive Transcranial Magnetic Stimulation on the Prognosis of Elderly Surgical Patients
Exploring the effects of repeated transcranial magnetic stimulation (rTMS) during the perioperative period on the incidence of postoperative delirium, postoperative cognitive dysfunction, and chronic postoperative pain in elderly…
- Conditions
- Postoperative Delirium, Postoperative Cognitive Dysfunction, Chronic Post-surgical Pain
- Trial name
- NCT06392919
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 352 people
- Sponsor
- Affiliated Hospital of Nantong University
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