Clinical trials: Pain, Chronic Disease
Chronic Shoulder Pain, Shoulder Impingement Syndrome
Ultrasound-Guided Suprascapular Nerve RFA vs Steroid-Local Anesthetic Injection in Chronic Shoulder Pain
This study aims to compare the clinical effectiveness of two interventional treatments for chronic shoulder pain related to suprascapular nerve pathology: ultrasound-guided suprascapular nerve block and suprascapular nerve…
- Conditions
- Chronic Shoulder Pain, Shoulder Impingement Syndrome, Rotator Cuff-Related Shoulder Pain, Suprascapular Nerve-Related Shoulder Pain
- Trial name
- NCT07302490
- Testing
- Pulsed Radiofrequency (PRF) of the Suprascapular Nerve, Suprascapular Nerve Block with Local Anesthetic and Corticosteroid
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Nida Koçer Nazlıgül
Pain, Sleep
Effects of Tactile Touch on Chronic Pain in Parkinson´s Disease
The Parkitouch study compared the effects on pain, sleep quality and HealthRelated Quality of Life (HRQoL) among 44 participants with Parkinson´s Disease for at least two years and chronic pain.The two groups were randomized to…
- Trial name
- NCT01734876
- Testing
- Tactile Touch, Rest To Music
- Where
- Sweden
- Volunteers
- 45 people
- Sponsor
- Region Jönköping County
Peripheral Nerve Injuries
Chronic Neuropathic Pain After Nerve Repair Hand Surgery
This study intends to compare the patients with pain with those who underwent same procedure without developing pain. The patients with pain and without pain will be further analyzed in respect to clinical differences, biomarkers…
- Trial name
- NCT03174665
- Testing
- No intervention
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Non-specific Chronic Low Back Pain, Healthy Volunteer
Behavioral Indicators of Pain Representation
The goal of this observational study is to compare the postural response to the mental simulation of everyday situations identified as painful in participants with non-specific low back pain and healthy volunteers.
- Trial name
- ICOR (NCT06669767)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universite de Picardie Jules Verne
Low Back Pain
Effects of Pain Neuroscience Education With Sensory Discrimination Training Among Patients With Chronic Low Back Pain
The current study is a double-blind, parallel-group randomized controlled trial involving 80 participants with chronic low back pain.
- Trial name
- NCT07284407
- Testing
- Pain Neuroscience Education with Sensory Discrimination Training and Core Stability Exercises, Pain Neuroscience Education and Core stability Exercises
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Coronary Artery Diseases
BIOFLOW-III VIP Russia Registry Orsiro Stent System
Clinical evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES). Along with it, an explanatory (hypothesis-finding) problem will be investigated, whether the patient's body…
- Trial name
- NCT02247492
- Where
- 7 sites in Russia
- Volunteers
- 200 people
- Sponsor
- Biotronik Russia
Chronic Pain
Development of an Online Program to Help Manage Chronic Pain in Children and Teenagers
This research seeks to develop an internet-based program to help teenagers manage pain at home using a variety of techniques from physiotherapy, medicine, psychology and nursing.
- Trial name
- NCT03992976
- Testing
- Online Chronic Pain Management Intervention for Teenagers
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Southampton
Chronic Pain, Fibromyalgia
Consensus-Based vs. Standardized Physiotherapy for Fibromyalgia
This study compares a new, consensus-based physiotherapy program to standard physiotherapy for people with fibromyalgia. The new program uses recommendations from experts, including education about pain, personalized exercise…
- Trial name
- NCT06913868
- Testing
- Consensus-Based Physiotherapy Program, Standardized Physiotherapy Care
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Al Hayah University In Cairo
Pain, Neuralgia, Postherpetic
A Study to Evaluate the Efficacy, Safety, and Tolerability of JNJ-42160443 in Patients With Neuropathic Pain (Postherpetic Neuralgia and Post-traumatic Neuralgia)
The purpose of this study is to evaluate the safety and effectiveness of JNJ-42160443 in the treatment of moderate to severe neuropathic pain in patients with a diagnosis of postherpetic neuralgia and post-traumatic neuralgia.
- Conditions
- Pain, Neuralgia, Postherpetic, Neuralgia, Mononeuropathies
- Trial name
- NCT00964990
- Testing
- JNJ-42160443
- Where
- 48 sites in United States, Belgium and 2 more
- Volunteers
- 112 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Addiction
Safety and Tolerability of Cannabidiol Among Persons With Opioid Use Disorder Receiving Methadone or Buprenorphine
The overarching goal of this study is to evaluate the potential of Cannabidiol (CBD) as an adjunctive treatment for comorbid opioid use disorder (OUD) and chronic pain.
- Trial name
- NCT05076370
- Testing
- CBD Day 1, CBD Day 2, CBD Day 3
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Yale University
Lumbar Radiculopathy
Effect of Transfer of Energy Capacitive and Resistive on Chronic Discogenic Sciatica
The goal of this clinical trial is to evaluate the effect of Transfer of Energy Capacitive and Resistive (TECAR) on pain, functional disability and electrophysiological parameters in adults with chronic discogenic sciatica .
- Trial name
- NCT07841405
- Testing
- Transfer of Energy Capacitive and Resistive (TECAR) therapy, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Endometriosis, Post Operative Pain
The Using Postoperative Ketamine and Exploring the Effect on Endometriosis Pain (UPKEEEP) Study
This is a randomized, single blinded, placebo-controlled trial to study the effectiveness of a subanesthetic dose (0.6 mg/kg) of ketamine versus placebo (saline) on postoperative pain and pain on adult female chronic pelvic pain…
- Trial name
- NCT05229653
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- NYU Langone Health
Neuropathic Pain, Radiculopathy
Comparison of Two Modes of Transcutaneous Electrical Nerve Stimulation (TENS) in Chronic Neuropathic Radiculalgia
This study will compare 2 types of Transcutaneous Electrical Nerve Stimulation (TENS) to treat chronic neuropathic pain. TENS involves the application of electrical stimulation to the skin via surface electrodes to stimulate…
- Trial name
- CROSS-TENS (NCT04169477)
- Testing
- CEFAR Primo Pro (TENS device)
- Where
- 4 sites in France
- Volunteers
- 74 people
- Sponsor
- Lille Catholic University
Pain, Pain, Acute
Assessing Opioid Care Practices Using CPV Patient Simulation Modules
This study will test the quality of opioid-related physician care decisions using a patient-simulation based measurement and feedback approach that combines multiple-choice care decisions with real-time, personalized scoring and…
- Conditions
- Pain, Pain, Acute, Pain, Chronic, Pain, Neuropathic
- Trial name
- NCT04080037
- Testing
- Quality IQ Patient Simulations
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Qure Healthcare, LLC
Chronic Pain, Nociplastic Pain
Internet-Delivered Psychological Treatments for Chronic Pain in Adolescents: ACT and Pain Education.
One in four children in Sweden experiences chronic pain. For many, the pain is temporary, but for about 5% it significantly affects daily life, leading to sleep problems, school absence, and reduced physical activity.
- Conditions
- Chronic Pain, Nociplastic Pain, Pain Management, Acceptance and Commitment Therapy
- Trial name
- NCT06981312
- Testing
- Acceptance and Commitment Therapy, Pain Science Education
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Region Stockholm
Multiple Sclerosis
Comparison of the Efficacy and Mechanisms for MBCT and CT for Multiple Sclerosis (MS) Chronic Pain
Chronic pain is a pervasive, serious problem for many individuals with multiple sclerosis (MS) that is typically inadequately treated by medications alone.
- Trial name
- NCT02012439
- Testing
- Mindfulness Based Cognitive Therapy, Cognitive Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Washington
Musculoskeletal Pain, Chronic Pain
The PROACTIVE Study for Black Elders
Chronic musculoskeletal pain (CMP), while a leading cause of physical disablement, is a neglected national health disparity issue in Black communities.
- Conditions
- Musculoskeletal Pain, Chronic Pain, Osteoarthritis, Pain, Chronic
- Trial name
- PROACTIVE (NCT06512727)
- Testing
- PROACTIVE Intervention
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Opioid-induced Constipation
ALK37-003: A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation (OIC)
The purpose of this study is to assess the safety and tolerability of RDC-1036 (ALKS 37) in adults with opioid-induced constipation (OIC) following repeat dose administration
- Trial name
- NCT01100151
- Testing
- RDC-1036 (ALKS 37)
- Where
- 11 sites in United States
- Volunteers
- 60 people
- Sponsor
- Alkermes, Inc.
Coronary Disease, Coronary Artery Disease
COMPLEX Registry - a Prospective COhort Study to Describe the Management and Outcomes of Patients Presenting with CompLEX and Calcified Coronary Artery Disease
The purpose of the COMPLEX Registry is to prospectively and retrospectively collect baseline, clinical and procedural data of patients who have undergone PCI or CABG for complex and/ or calcified chronic CAD, irrespective of…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis, Coronary Arteriosclerosis
- Trial name
- COMPLEX (NCT06075602)
- Testing
- Impact of current PCI techniques/ devices in complex coronary artery lesions
- Where
- Switzerland
- Volunteers
- 5,000 people
- Sponsor
- Luzerner Kantonsspital
Prostatitis
CBD-based Therapy to Attenuate Non-bacterial Prostatitis Symptoms
Efficacy and safety of the medical device rectal CANNEFF® SUP suppositories containing two active ingredients cannabidiol (CBD) and hyaluronic acid (HA) in alleviating non-bacterial prostatitis symptoms and improving quality of…
- Trial name
- Urol-CBD (NCT06968910)
- Testing
- CANNEFF® SUP rectal suppositories
- Where
- Czechia
- Volunteers
- 35 people
- Sponsor
- Palacky University
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