Clinical trials: Pain, Chronic Disease
Cervical Pain, Posterior, Swallowing Difficulties
Tongue Pressure in Middle-Aged and Elderly Individuals With Chronic Cervical Pain
The goal of the cross-sectional study is to explore the impact of neck pain on tongue pressure in the middle-aged and elderly population and analyze the effects of different cranio-cervical positioning on tongue pressure…
- Conditions
- Cervical Pain, Posterior, Swallowing Difficulties, Swallowing Disorders
- Trial name
- NCT07021586
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Knee Osteoarthritis
Effectiveness of Ultrasound Guided Adductor Canal Block on Chronic Pain in Knee Osteoarthritis
Adductor canal block has become popular as effective mean for pain relief following knee surgery.This block has not been checked in chronic pain patients.The purpose of this study is to assess the efficacy and safety of adductor…
- Trial name
- NCT02695654
- Testing
- Levobupivacaine, Clonidine
- Where
- Slovenia
- Volunteers
- 77 people
- Sponsor
- Mensur Salihovic
Critical Limb Ischemia
UT-15C SR in the Treatment of Critical Limb Ischemia
This study will evaluate UT-15C sustained release tablets in subjects experiencing ischemic lower limb rest pain related to advanced peripheral arterial disease.
- Trial name
- NCT00445159
- Testing
- UT-15C SR (treprostinil diethanolamine) 1mg oral tablets
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Southern Arizona Vascular Institute
Ketamine, Chronic Post Thoracotomy Pain
KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain
We assessed the effects of the N Methyl aspartate receptor antagonist Ketamine on long-term post thoracotomy pain. We hypothesized that ketamine could prevent supersensitization of the central nervous system involved in this…
- Conditions
- Ketamine, Chronic Post Thoracotomy Pain, Thoracotomy, Pain
- Trial name
- NCT00224588
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Essential Hypertension, Chronic Stable Angina
Observational Study to Evaluate the Safety of DILATREND SR Cap. in Korean Patients With Essential Hypertension, Chronic Stable Angina and Congestive Heart Failure
The purpose of this study is to Evaluate the Safety of DILATREND SR Cap. in Korean Patients with Essential hypertension, Chronic stable angina and Congestive heart failure for 52 weeks.
- Conditions
- Essential Hypertension, Chronic Stable Angina, Congestive Heart Failure
- Trial name
- DELIGHT (NCT03063697)
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Chong Kun Dang Pharmaceutical
Osteoarthritis, Arthritis, Rheumatoid
Low Dose Naltrexone for Chronic Pain in Osteoarthritis and Inflammatory Arthritis
Over 100 million Americans report chronic pain. One of the most common causes of chronic pain is osteoarthritis (OA). OA is attributable to "wear and tear," but reasons for pain are complex.
- Conditions
- Osteoarthritis, Arthritis, Rheumatoid, Arthritis, Psoriatic
- Trial name
- NCT04115020
- Testing
- Naltrexone
- Where
- United States
- Sponsor
- Brigham and Women's Hospital
Leg Ulcer
Topical Sevoflurane for Treatment of Chronic Leg Ulcers
Patients with painful non-healing leg ulcer will be enrolled in the clinical single-blinded randomized study. The active treatment group will have sevoflurane applied at approximately 1 ml/cm2 at the start of wound treatment, the…
- Trial name
- NCT05303805
- Testing
- Sevoflurane, Cyteal
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- Charles University, Czech Republic
Patellofemoral Pain Syndrome
Effectiveness Trial for Evaluating IAHA for PFPS
The purpose of this study is to determine the safety and effectiveness of intra-articular hyaluronan (IAHA) injections for the treatment of symptomatic patellofemoral pain syndrome (PFPS) and determine if this treatment can…
- Trial name
- PFPS (NCT01811654)
- Testing
- Intra-Articular Hyaluronic Acid-Euflexxa
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- NYU Langone Health
Benign Prostatic Hyperplasia, Chronic Prostatitis
JALYN for Benign Prostatic Hyperplasia (BPH) and Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)
Benign Prostatic Hyperplasia (BPH) describes a common medical condition in men over 45 associated with voiding (obstructive) and storage (irritative) lower urinary tract symptoms and is in part related to prostate enlargement and…
- Trial name
- NCT01830829
- Testing
- Jalyn
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- Dr. J. Curtis Nickel
Sickle Cell Disease
Imatinib for Pain in Sickle Cell Anemia
In this protocol, the investigators propose to evaluate the biochemical effects of imatinib on sickle red blood cells (RBCs). Patients will be administered imatinib mesylate orally following the guidelines previously established…
- Trial name
- IMPACT (NCT03997903)
- Testing
- Imatinib Mesylate
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Pain
The Effectiveness of Continuous Ketamine Infusion (KONTINUE)
There are different treatment for chronic pain. One possible treatment is intravenous infusions of ketamine.
- Trial name
- KONTINUE (NCT06131970)
- Where
- Monaco
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Princesse Grace
Lumbar Radiculopathy
PNF With and Without Electrical Stimulation in Patients With Chronic Lumbar Radiculopathy
Numerous researches have shown how PNF is been used to treat non specific low back pain, subacromial impingement, cervical radiculopathy and many others.
- Trial name
- NCT06707779
- Testing
- PNF with electrical stimulation, PNF without electrical stimulation
- Where
- Pakistan
- Volunteers
- 48 people
- Sponsor
- Riphah International University
Neuralgia
Towards Individualized Deep Brain Stimulation Treatment of Chronic Neuropathic Pain
Chronic neuropathic pain affects millions of individuals worldwide. It causes marked reduction of health, utility and quality of life and represents a considerable economic burden to society due to loss of work capacity and large…
- Trial name
- DBSforPain (NCT01899170)
- Testing
- Deep brain stimulation, Cervel Neurotech, Multi-coil TMS, 11C-Carfentanil
- Where
- Denmark
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders
Methadone, Morphine, or Oxycodone in Treating Pain in Patients With Cancer
RATIONALE: Methadone, morphine, or oxycodone may help relieve pain caused by cancer. It is not yet known whether methadone is more effective than morphine or oxycodone in treating pain in patients with cancer.
- Conditions
- Brain and Central Nervous System Tumors, Chronic Myeloproliferative Disorders, Leukemia, Lymphoma
- Trial name
- NCT00726830
- Testing
- methadone hydrochloride, morphine sulfate, oxycodone hydrochloride
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Low Back Pain
Validation of a Virtual Reality Timed Up and Go Test in Adults With Chronic Non-Specific Low Back Pain
This study evaluates whether an immersive virtual reality (VR) version of the Timed Up and Go (TUG) test can accurately measure functional mobility in adults with chronic non-specific low back pain.
- Trial name
- VRTUG-CLBP (NCT07402499)
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Selcuk University
Chronic Myeloproliferative Disorders, Leukemia
Treatment for Chronic Pain in Patients With Advanced Cancer
RATIONALE: Different drug formulations and combinations of drugs may help patients with chronic pain live more comfortably. It is not yet known which regimen is most effective for chronic pain.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003687
- Testing
- dextromethorphan hydrobromide, morphine sulfate
- Where
- 4 sites in Canada
- Volunteers
- 87 people
- Sponsor
- NCIC Clinical Trials Group
Hypertension, Coronary Disease
Analyzing How Genetics May Affect Response to High Blood Pressure Medications
High blood pressure is one of the most common health problems in the United States. There are many medications to treat high blood pressure, but there is a large variance in how people respond to these medications.
- Conditions
- Hypertension, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00563901
- Where
- 2 sites in United States
- Volunteers
- 37,939 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
STEMI, NSTEMI
Prediction of Adverse Events From Non-PCI Coronary Plaques Using Machine Learning
The aim of our project is to predict, with the help of artificial intelligence (AI) and machine learning techniques, the natural history of non-flow-limiting coronary stenoses and to develop and validate a machine learning risk…
- Conditions
- STEMI, NSTEMI, Chronic Coranary Sindrome, Unstable Angina (UA)
- Trial name
- Predict AI (NCT07866144)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Knee Osteoarthritis
Investigating Racial Differences in Diet Benefits for Knee Osteoarthritis
Knee osteoarthritis (OA) is the most prevalent form of arthritis and race is a risk factor for poor outcomes. African-Americans (AAs) report greater OA-related disability and pain severity compared to their Non-Hispanic White…
- Trial name
- NCT04343716
- Testing
- Low-carbohydrate diet
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Alabama at Birmingham
Chronic Migraine, Headache, Fibromyalgia Syndrome
Fibromyalgia Syndrome on Patients With Chronic Migraine
The aim of this study to evaluate the effects of fibromyalgia syndrome accompanying women with chronic migraine on pain, quality of life, sleep, anxiety and depression, central sensitization and functionality.
- Conditions
- Chronic Migraine, Headache, Fibromyalgia Syndrome, Chronic Pain Syndrome, Central Sensitisation
- Trial name
- NCT05381012
- Testing
- Allodynia, quality of life, sleep, anxiety and depression, disability, and central sensitization, Fibromyalgia syndrome
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul University - Cerrahpasa
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.