Clinical trials: Pain, Chronic Disease
Chronic Pain, Neuralgia
Acupuncture Versus Conventional Treatment for Chronic Pain in Patients With Chronic Kidney Disease
This study evaluated acupuncture plus optimized conventional pharmacological treatment compared with optimized conventional pharmacological treatment alone for chronic pain in adults with chronic kidney disease receiving…
- Conditions
- Chronic Pain, Neuralgia, Renal Insufficiency,Chronic
- Trial name
- NCT07891819
- Testing
- Acupuncture, Optimized conventional pharmacological treatment
- Where
- Brazil
- Volunteers
- 110 people
- Sponsor
- Federal University of São Paulo
Chronic Total Occlusion of Coronary Artery, Angina Pectoris
Observational Registry on Clinical Outcome After Diagnosis of Chronic Total Occlusions
This registry aims at enrolling all consecutive patients presenting with at least one chronic total occlusion at coronary angiogram as diagnosed during angiography in our catheterization laboratory during 1 year.
- Trial name
- PETS-CTO (NCT04145167)
- Where
- Belgium
- Volunteers
- 400 people
- Sponsor
- Ziekenhuis Netwerk Antwerpen (ZNA)
Stable Chronic Angina, Ischemic Heart Disease
Effect of Remote Intervention in Patients With SCAD
The study was a multicenter, two-arm, parallel, open-label, prospective clinical trial that evaluated a remote intervention with 1 year of follow-up.
- Conditions
- Stable Chronic Angina, Ischemic Heart Disease, Coronary Artery Disease, Heart Diseases
- Trial name
- NCT04795492
- Testing
- remote intervention, Routine outpatient follow-up
- Where
- China
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Abdominal Pain
Chronic Abdominal Pain After Gastric Bypass
The study aims to explore patients perception of chronic abdominal pain after Roux en Y gastric bypass surgery for morbid obesity. The investigators aim to describe characteristics of symptoms of pain.
- Trial name
- NCT03455998
- Testing
- questionnaires
- Where
- Norway
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Chronic Coronary Syndrome, Hypertension
Benidipine in Hypertensive and/or Chronic Coronary Syndrome Patients
Evaluation of the clinical outcomes of Benidipine initiated by physician's preference in patients with hypertension and/or angina pectoris (chronic coronary syndrome) presenting to cardiology outpatient clinics in Türkiye.
- Conditions
- Chronic Coronary Syndrome, Hypertension, Angina Pectoris
- Trial name
- BenidipineTR (NCT06808321)
- Testing
- Benidipine Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 1,659 people
- Sponsor
- The Society of Prevention and Awareness of Cardiovascular Diseases
Chronic Pancreatitis, Recurrent Pancreatitis
VR Pilot for Pancreatitis
The purpose of the research is to test the feasibility and preliminary impact of a home-based, standardized, gut-directed, virtual reality cognitive behavioral therapy (VR CBT) on clinical and functional outcomes of patients with…
- Trial name
- NCT06362187
- Testing
- Gut Directed VR
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cedars-Sinai Medical Center
Parkinson Disease
Foot Reflexology on Chronic Pain in Parkinsonian Patients
Pain is one of the non-motor symptoms of Parkinson's disease still poorly known and misdiagnosed and its management is complex. This encourage to explore new non-drug therapeutic paths, such as foot reflexology (FR).
- Trial name
- DOREPAR (NCT04705207)
- Testing
- reflexology massage
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Hyperlipidemia, Hypercholesterolemia
Patient and Provider Assessment of Lipid Management Registry
The purpose of the Patient and Provider Assessment of Lipid Management Registry (PALM) is to gain a better understanding of physicians' cholesterol medication prescribing practices, patient and physician attitudes and beliefs…
- Conditions
- Hyperlipidemia, Hypercholesterolemia, Cardiovascular Disease, Diabetes
- Trial name
- PALM (NCT02341664)
- Where
- 14 sites in United States
- Volunteers
- 7,658 people
- Sponsor
- Duke University
Analgesia, Post Operative Pain
Morphine vs Sufentanil PCA: Same Same or Different?
Patient-controlled intravenous analgesia (PCA) has already proven its quality. However, with new strategies starting to emerge and the current concept of opioid sparing, it is a goal to find the optimal PCA strategy capable of…
- Conditions
- Analgesia, Post Operative Pain, Patient Satisfaction, Chronic Pain
- Trial name
- NCT05259098
- Testing
- Sufentanil Sublingual Tablet System, Intravenous Patient-Controlled Analgesia with morfine
- Where
- Portugal
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hospital Central do Funchal
Hyperalgesia, Pain
Local Anesthetic Infusion and Sternotomy
Cardiac surgery often induces acute postoperative pain and moreover chronic dysesthesia frequently occur long-term after sternotomy.
- Trial name
- CARDIODOLAL (NCT00802048)
- Testing
- Local anesthetic (Ropivacaine), Saline
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Chronic Illness, Hematologic Malignancy
Distracting Through Procedural Pain and Distress
Children with acute and chronic illness undergo frequent, painful, and distressing procedures. This randomized control trial was used to evaluate the effectiveness of guided imagery (GI) vs virtual reality (VR) on the procedural…
- Conditions
- Chronic Illness, Hematologic Malignancy, Bone Marrow Transplant Infection, Oncology
- Trial name
- NCT04892160
- Testing
- Guided Imagery, Virtual Reality
- Where
- 2 sites in United States
- Volunteers
- 67 people
- Sponsor
- Medical College of Wisconsin
Chronic Pain, Marfan Syndrome
Single-Session "Empowered Relief" Class for Marfan Syndrome and Related Conditions
Empowered Relief (ER) is a 1-session pain relief skills intervention that is delivered in-person or online by certified clinicians to groups of patients with acute or chronic pain.
- Conditions
- Chronic Pain, Marfan Syndrome, Vascular Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome
- Trial name
- NCT05980104
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Stanford University
Mitochondrial Diseases, Developmental Delay Disorder
Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders
Background: Small-Fiber-Neuropathy describes the degeneration of mildly or unmyelinated nerve fibers and causes neuropathic pain and autonomic dysfunction.
- Conditions
- Mitochondrial Diseases, Developmental Delay Disorder, Small Fiber Neuropathy, Cerebral Palsy
- Trial name
- SFN_children (NCT05645874)
- Testing
- Skin biopsy
- Where
- Germany
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Heinrich-Heine University, Duesseldorf
Low Back Pain
Effects of Core Exercise in Low Back Pain
Non-specific low back pain in one of the main causes of disability for health care worldwide. The effectiveness of therapeutic exercise, of kinesio tape and of manual therapy in the treatment of low back pain is evaluated, but…
- Trial name
- NCT05544890
- Testing
- Exercise, Manual Therapy, Kinesiotape
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Universitat Jaume I
Cirrhosis, Hepatic Fibrosis
Prevalence of Pain in Hospitalized Cirrhotic Patients
According to the WHO, pain is an "unpleasant sensory and emotional experience, linked to existing or potential tissue damage, or described in terms suggestive of such damage".
- Conditions
- Cirrhosis, Hepatic Fibrosis, Pain, Acute, Pain, Chronic
- Trial name
- LIVERPAIN (NCT06062108)
- Testing
- Pain evaluation
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer
Persian Gulf Syndrome, Chronic Fatigue Syndrome
Acupressure for Pain Management and Fatigue Relief in Gulf War Veterans
This study will provide symptomatic veterans with acupressure treatment and determine its effectiveness in fatigue relief and pain management for Gulf War Illness (GWI).
- Trial name
- NCT02075489
- Testing
- Acupressure treatment., Reiki
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- The Cleveland Clinic
Chronic Pain Patients, Medical Cannabis Users
Medical Cannabis and Behavior
This study will assess cognition, neural function, and drug exposure in chronic pain patients who have been prescribed medical cannabis and will differentiate outcomes based on use of specific CBD-dominant versus THC-dominant…
- Trial name
- NCT06808048
- Testing
- Cognitive testing, Task-based fMRI measure of face-name and verbal learning
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Minnesota
Single-visit, Periapical Periodontitis
Postoperative Pain and Success of Single-Visit Root Canal Treatment Using Different Root Canal Sealers in Asymptomatic Teeth
This study evaluates the postoperative pain and long-term clinical and radiographic success of single-visit primary root canal treatment in asymptomatic teeth with periapical lesions.
- Trial name
- NCT07868315
- Testing
- One-Fill, TotalFill, AH Plus + Single Cone
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul Medipol University Hospital
Neck Pain, Low Back Pain
Study to Demonstrate That Muscle Pattern Recognition (MPR) is an Effective Evaluation Tool for Musculoskeletal Neck or Back Pain
The investigators hypothesize that non able-bodied participants with reported acute, sub-acute, or chronic symptoms of neck or back pain of a musculoskeletal origin will have magnetic resonance imaging (MRI), X-ray and blood…
- Trial name
- NCT00134225
- Testing
- Muscle Pattern Recognition (MPR)
- Where
- 4 sites in United States, Canada
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- iTech Medical, Inc.
Chronic Pain, Sexual Dysfunction
Study Comparing Total Extraperitoneal Patch "TEP" Versus Lichtenstein According Chronic Pain
The purpose of this study is to se if there is a difference regarding chronic pain and sexual dysfunction one and tree years after laparoscopic un fixated preperitoneal mesh versus gold standard open fixated on lay mesh in…
- Trial name
- TEP-LICH (NCT00803985)
- Testing
- Total Extraperitoneal repair (TEP), Lichtenstein
- Where
- Sweden
- Volunteers
- 416 people
- Sponsor
- Skane University Hospital
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