Clinical trials: Pain, Chronic Post-Surgical
Pain After Surgery, PSP
Intraoperative Bupivacaine Injection to Reduce Acute and Chronic Pain After TVT/TVT-O Surgery. Randomized Double-Blind Trial
This randomized, double-blind controlled trial will evaluate whether intraoperative injection of bupivacaine at the sling insertion site reduces postoperative pelvic and thigh pain in women undergoing TVT or TVT-O surgery for…
- Conditions
- Pain After Surgery, PSP, Chronic Pain Syndrome, Local Anesthesia Infiltration
- Trial name
- PAIN-TVT (NCT07429019)
- Testing
- Bupivacain (Postoperative)
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Postoperative Pain, Postoperative Pain, Acute
Incidence of Chronic Pain After Thoracic Surgery
Thoracotomy and video-assisted thoracic surgery procedures are frequently performed in thoracic surgery. It is widely accepted that thoracotomy causes severe acute pain.
- Conditions
- Postoperative Pain, Postoperative Pain, Acute, Postoperative Pain, Chronic, Video-Assisted Thoracoscopic Surgery
- Trial name
- NCT05145153
- Testing
- Thoracic surgery application
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Chronic Postsurgical Pain, Chronic Post-surgical Pain
Prevention of Postsurgical Chronic Pain in Children and Adolescents (PREVENDOL)
Chronic postsurgical pain is a health problem with a great societal impact: approximately 20% of all children and adolescents undergoing surgery will develop chronic pain.
- Conditions
- Chronic Postsurgical Pain, Chronic Post-surgical Pain, Chronic Postoperative Pain, Chronic Post-operative Pain
- Trial name
- NCT06638437
- Testing
- Cognitive-behavioral therapy
- Where
- 3 sites in Spain
- Volunteers
- 125 people
- Sponsor
- University Rovira i Virgili
Coronary Artery Bypass Grafting, Postoperative Pain
Preoperative Pain Neuroscience Education in Patients Undergoing CABG
This randomized controlled trial evaluated the effects of a single preoperative pain neuroscience education (PNE) session on postoperative pain-related outcomes in patients undergoing elective coronary artery bypass grafting…
- Trial name
- PNE-CABG (NCT07783750)
- Testing
- Pain Neuroscience Education
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- İsmail Palalı
Postoperative Analgesia, Hand Strength
Long-term Outcomes of Breast Cancer Patients After Wound Infiltration Analgesia
In the study that was conducted from 05.01.2009 - 31.12.2012. 120 patients were examined. By drawing random numbers, the patients were randomized into 3 groups for postoperative analgesia: 1. Diclofenac 2 mg/kg/day - control, 2.
- Conditions
- Postoperative Analgesia, Hand Strength, Health Related Quality of Life, Chronic Shoulder Pain
- Trial name
- NCT05829707
- Testing
- Diclofenac Sodium, Levobupivacaine bolus analgesia, Levobupivacaine PCA group
- Volunteers
- 120 people
- Sponsor
- Osijek University Hospital
Knee Pain Chronic
Chronic Pain and Functional Prognosis After Total Knee Replacement: Continuous Locoregional Analgesia by Catheter to the Femoral Triangle Versus Tissue Infiltration as Part of an Improved Rehabilitation After Surgery Approach
The prevalence of Chronic Post-Surgical Pain (CPSP) after knee replacement, defined as pain greater than or equal to 4/10 on the visual analogue scale after the third postoperative month, is recognised as high, with an average of…
- Trial name
- TKAFTER (NCT03998813)
- Testing
- Ropivacaine
- Where
- 5 sites in France
- Volunteers
- 287 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Cardiac Surgery, Sternotomy
Pecto-Intercostal Fascial Plane Block Catheter Trial for Reduction of Sternal Pain
One of the most painful aspects of open heart surgery is the incision made through the skin and the sternum to access the heart (a "sternotomy").
- Conditions
- Cardiac Surgery, Sternotomy, Acute Pain
- Trial name
- NCT05054179
- Testing
- Ropivacaine 0.2% Injectable Solution Bolus, Normal Saline Infusion, Ropivacaine 0.2% Injectable Solution Infusion
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- University of British Columbia
Pelvic Pain
Long-term Management of Patients Surgically Treated for Chronic Pelvic Pain by Minimally Invasive Surgery
It is a retrospective observational study based on the analysis of the medical records of patients treated for chronic pelvic pain and benign gynecological pathologies at the Gynecology Unit of the University Hospital of Modena…
- Trial name
- NCT04652011
- Testing
- Minimally Invasive Gynecologic Surgery, osteopathic manipulative treatment, Pain killer
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Neuropathic Pain, Complex Regional Pain Syndromes (CRPS)
Sub-threshold DRG Stimulation vs Sham in Established Responders
The goal of this clinical trial is to learn if sub-threshold dorsal root ganglion (DRG) stimulation provides pain relief beyond placebo in adults with chronic neuropathic pain who already have an implanted DRG stimulator.
- Conditions
- Neuropathic Pain, Complex Regional Pain Syndromes (CRPS), Causalgia, Chronic Pain
- Trial name
- DRG-SHAM (NCT07170722)
- Testing
- Subtreshhold DRG-S
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Umeå University
Low Back Pain, Chronic Pain
Non-pharmacological Treatment for Pain After Spine Surgery
This study will compare the effectiveness of two pain management pathways (standard vs. enriched) for patients undergoing lumbar spine surgery in the Military Health System (MHS).
- Conditions
- Low Back Pain, Chronic Pain, Surgery, Back Pain, Low
- Trial name
- NCT04770480
- Testing
- Standard Care (SC), Enriched Pain Management Pathway (EPM)
- Where
- 3 sites in United States
- Volunteers
- 267 people
- Sponsor
- Dan Rhon
Pneumothorax
Chronic Pain After Video-assisted Thoracoscopic Surgery (VATS) Surgery for Pneumothorax
The study will investigate characteristics of chronic pain after VATS surgery with two different sizes of videoscopic equipment.
- Trial name
- NCT00969423
- Testing
- 5mm videoscope, 10mm videoscope
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Carcinologic Ear, Nose, and Throat (ENT) Surgery
Intravenous Lidocaine in Carcinologic ENT Surgery: A Trial for Evaluation of Opioid Saving Strategy and Chronic Post-surgical Pain (ELICO)
Lidocaine, local anesthetic used for more than five decades, is being intravenously administered aiming at managing pain in different types of surgeries with promising results.
- Trial name
- ELICO (NCT02894710)
- Testing
- Lidocaine 20mg/ml
- Where
- 2 sites in France
- Volunteers
- 143 people
- Sponsor
- Hospices Civils de Lyon
Thoracic
Effects of Thoracic Erector Spinae Plane Blockade on Acute and Chronic Pain After Video Assisted Thoracoscopic Surgery (VATS)
This is a prospective randomized study intended to assess the efficacy of erector spinae plane analgesia on acute and chronic postoperative pain for VATS procedures.
- Trial name
- NCT04208542
- Testing
- ESP block
- Where
- South Korea
- Volunteers
- 72 people
- Sponsor
- Yonsei University
Pain, Postoperative
Thoracic Paravertebral Blockade in Video Assisted Thoracoscopic Surgery (VATS)
Video-assisted thoracoscopic surgeries (VATS) include severe postoperative acute pain which is also a predictor of chronic pain.
- Trial name
- VATS (NCT02302586)
- Testing
- Thoracic paravertebral block (TPVB), Patient Controlled Analgesia (IV PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Chronic Post Surgical Pain, Functional Recovery
Incidence of Chronic Pain in Patients Undergoing Knee Arthroplasty Within a Fast-Track Protocol
The goal of this study is to learn about pain after knee replacement surgery. The surgery uses a fast-recovery program called Enhanced Recovery After Surgery (ERAS).
- Conditions
- Chronic Post Surgical Pain, Functional Recovery, ERAS, Chronic Opioid Use
- Trial name
- NCT07673276
- Where
- Belgium
- Volunteers
- 153 people
- Sponsor
- University Hospital, Ghent
Back Pain, Spinal Stenosis
Perioperative ACT for Preventing CPSP
The present study aims to adapt and modify a brief perioperative Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Back Pain, Spinal Stenosis, Spondylosis, Spondylolisthesis
- Trial name
- PREPS (NCT06750874)
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Samantha Meints
Pain
Chronic Neuropathic Pain After Lung Surgery: Prevalence and Predictive Factors
Chronic post-thoracotomy pain is the most common long-term complication that occurs after a thoracotomy with a reported incidence of up to 80%.
- Trial name
- DOLORPOUMON (NCT02928003)
- Testing
- Lung surgery
- Where
- 2 sites in France
- Volunteers
- 166 people
- Sponsor
- Hopital Foch
Chronic Postoperative Pain, Chest Pain
The Effectiveness of Thoracal Epidural Steroid and Local Anesthetic Injection
The primary objective was to evaluate the effectiveness of thoracic interlaminar epidural injections in alleviating pain and enhancing function in patients suffering from chronic mid and/or upper back pain.
- Conditions
- Chronic Postoperative Pain, Chest Pain, Back Pain
- Trial name
- NCT06507995
- Testing
- thoracic interlaminar epidural injection
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara University
Chronic Postoperative Pain, Cesarean Section Complications
Monocentric Observational Study: Postoperative Pain After Cesarean Section: Incidence and Risk Factors.
The purpose of this prospective study was to assess chronic pain 3, and 12 months after cesarean delivery in a cohort of women in University hospital La Paz.
- Trial name
- NCT04280432
- Testing
- CESAREAN
- Where
- Spain
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Breast Neoplasms, Pain, Postoperative
Serratus Anterior Plane Block to Prevent Chronic Postoperative Pain in Breast Cancer
Chronic postoperative pain (CPP) remains a disturbing and obscure clinical problem. The hypothesis of this trial is that a peripheral block of the serratus anterior plane block type preoperatively after a modified radical…
- Conditions
- Breast Neoplasms, Pain, Postoperative, Pain, Chronic, Post-Mastectomy Chronic Pain Syndrome
- Trial name
- USB22 (NCT05494281)
- Testing
- Serratus Anterior Plane Block with local anesthetic, Serratus Anterior Plane Block with saline solution
- Where
- Morocco
- Volunteers
- 94 people
- Sponsor
- Moroccan Society of Surgery