Clinical trials: Pain, Chronic Post-Surgical
Pain, Chronic, Intensive Care, Surgical
Chronic Pain After Surgical Intensive Care Admission: Incidence and Risk Factors: the DOLOCHROREA Study
The acute pain remains unfortunately a major health problem in intensive care patients. Several factors, such as cancer, traumatic injuries, surgery, scars, diagnostic or therapeutic procedure, could contribute to an increase in…
- Trial name
- DOLOCHROREA (NCT02541851)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Postoperative Cognitive Dysfunction, Postoperative Delirium
Effects of Perioperative Transauricular Vagus Nerve Electrical Stimulation on POD, POCD and CPSP
Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) occur in 11-51% of patients after surgery, and its prevalence increases with age.
- Conditions
- Postoperative Cognitive Dysfunction, Postoperative Delirium, Chronic Post Operative Pain
- Trial name
- NCT05439707
- Testing
- transaricular vagus nerve stimulation, fake transaricular vagus nerve stimulation
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Xuzhou Central Hospital
Pain, Back, Spinal Stenosis
PREventing Pain After Surgery
The present study aims to adapt and modify a brief presurgical Acceptance and Commitment Therapy (ACT) intervention aimed at preventing the transition to Chronic Post-Surgical Pain (CPSP) and reducing long-term opioid use.
- Conditions
- Pain, Back, Spinal Stenosis, Disc Herniation, Spondylosis
- Trial name
- PREPS (NCT05306665)
- Testing
- ACT intervention
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Brigham and Women's Hospital
Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain
Determining the Prognostic Value of Continuous Intrathecal Infusion
The purpose of this study will be to determine the efficacy and the prognostic value of a continuous intrathecal prognostic infusion test in an in-hospital setting for selecting patients who would have better long term outcomes…
- Conditions
- Lumbar Post-Laminectomy Syndrome, Chronic Low Back Pain, Vertebral Compression Fracture, Failed Back Surgery Syndrome
- Trial name
- NCT03523000
- Testing
- Continuous intrathecal prognostic infusion test, Bupivacaine, Fentanyl
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University Hospitals Cleveland Medical Center
Postoperative Pain, Chronic Postsurgical Pain
Erector Spinae Plane Block for Chronic Pain After Spinal Surgery
The aim of this study is to evaluate whether the erector spinae plane (ESP) block reduces acute and chronic postoperative pain in patients undergoing spinal surgery.
- Conditions
- Postoperative Pain, Chronic Postsurgical Pain, Spinal Surgery
- Trial name
- NCT07834502
- Testing
- NRS SCORE, Total tramadol consumption, Post Operative Pain Relievers
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Aydin Adnan Menderes University
Post-surgical Pain, Pain, Chronic
Intercostobrachial Nerve Sparing to Reduce Post-Surgical Pain
Sacrifice of the intercostobrachial nerve (ICBN) during surgery is associated with development of persistent post-surgical pain (PPSP), which affects up to 60% of breast cancer surgery patients.
- Conditions
- Post-surgical Pain, Pain, Chronic, Intercostal Pain, Breast Cancer
- Trial name
- INSPIRE (NCT03421522)
- Testing
- ICBN preservation surgery
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McMaster University
Cryotherapy Effect, Chronic Pain
Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection
Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection…
- Conditions
- Cryotherapy Effect, Chronic Pain, Lung Cancer, Surgery
- Trial name
- CRYO-VATS-2 (NCT05884099)
- Testing
- Cryoanalgesia AND single-injection paravertebral block, Single-injection paravertebral block
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Post-operative Analgesia, CSOM - Chronic Suppurative Otitis Media
Preemptive Pregabalin in Myringoplasty
The aim of this study was to investigate the effect of preemptive pregabalin on post-operative pain reduction after myringoplasty.
- Trial name
- NCT03603626
- Testing
- Pregabalin 150mg
- Where
- Nepal
- Sponsor
- Dhulikhel Hospital
Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute
Opioid Free Anaesthesia-Analgesia Strategy on Surgical Stress and Immunomodulation in Elective VATS-Lobectomy for NSCLC
Lobectomy is a major, high-risk surgical procedure that in addition to one-lung ventilation (OLV) exerts a potent surgical stress response.
- Conditions
- Systemic Inflammatory Response Syndrome, Postoperative Pain, Acute, Postoperative Pain, Chronic, Infections Postoperative
- Trial name
- NCT05172739
- Testing
- Opioid-Based Anesthesia-Analgesia Strategy, Opioid-free Anesthesia-Analgesia Strategy
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- University of Crete
Quality of Life, Living-donor Liver Transplantation
The Effect of Individualised Pain Education on Chronic Postoperative Pain Development and Quality of Life in Living Liver Donors
Chronic postoperative pain is defined as pain that is a continuation of acute pain or develops after a pain-free period, is localised to the surgical site, affects quality of life, and persists for at least 3 months after surgery…
- Conditions
- Quality of Life, Living-donor Liver Transplantation, Chronic Post Operative Pain, Pain Management
- Trial name
- NCT06609772
- Testing
- Individualised Pain Education
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Nazlican Bagci
Hernia, Inguinal, Hernia, Femoral
Chronic Pain After Groin Hernia Surgery in Women
The goal of this study was to evaluate chronic pain and reoperation rates due to recurrence after groin hernia surgery in women compared to men and surgical method.
- Trial name
- NCT04228536
- Testing
- Totally ExtraPeritoneal (TEP) repair, TransAbdominal PrePeritoneal (TAPP) repair, Open anterior mesh repair (OAM)
- Volunteers
- 44,915 people
- Sponsor
- Umeå University
Arrythmia, Chronic Pain
Acute and Chronic Pain After One-stage Hybrid Arrhythmia Ablation Surgery
After one-stage hybrid arrhythmia ablation surgery there are possible side effects like acute and chronic pain. There is a lot of research surrounding these pains but not specifically after one-stage hybrid arrhythmia ablation…
- Conditions
- Arrythmia, Chronic Pain, Acute Pain, Post Operative Pain
- Trial name
- NCT05211492
- Testing
- Questionnaire
- Where
- Belgium
- Volunteers
- 43 people
- Sponsor
- Universitair Ziekenhuis Brussel
Pain, Post Operative Pain
Patient Reported Outcomes, Postoperative Pain and Pain Relief After Day Case Surgery (POPPY)
Around 3 out of 4 operations in the UK are performed as day-case, meaning the patient goes home on the same day of their operation.
- Conditions
- Pain, Post Operative Pain, Opioid Use, Chronic Pain
- Trial name
- POPPY (NCT06008496)
- Testing
- Day case surgery
- Where
- United Kingdom
- Volunteers
- 7,839 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Chronic Pain
Effect of Intraoperative Infiltration With Bupivacain on the Development of Chronic Pain After Inguinal Hernia Repair
The effect of intraoperative infiltration of the operation site with bupivacain on the development of chronic pain is the object of our trial.
- Trial name
- NCT00484731
- Testing
- Infiltration with Saline, Infiltration with Bupivacaine
- Where
- Switzerland
- Volunteers
- 404 people
- Sponsor
- Luzerner Kantonsspital
Acute Pain, Chronic Postsurgical Pain
The Influence of Different Anesthesia on Acute and Chronic Postsurgical Pain After Thoracic Surgery
This study would compare acute and chronic postsurgical pain in patients underwent thoracic surgery with different anesthesia and analgesia methods, and explore the influencing factors.
- Trial name
- NCT03847363
- Testing
- epidural anesthesia, nerve block
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai Zhongshan Hospital
Mastectomy, Pain, Chronic
Affecting Factors for Chronic Pain After Mastectomy
Chronic post-mastectomy pain (CPMP) is a significant issue affecting many women after mastectomy. Factors like age, treatment type, and pre-surgery pain can increase the risk of developing this condition.
- Conditions
- Mastectomy, Pain, Chronic, Pain, Acute, Breast Surgery
- Trial name
- CPMP (NCT06592053)
- Testing
- Breast Cancer Surgery Pain
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Ankara Etlik City Hospital
Cerebral Palsy, Post-operative Pain
The Post-Operative Pain in Cerebral Palsy (POPPIES) Trial
Cerebral palsy is common. It affects approximately 3 per 1000 children. Hip displacement due to muscle tightness (spasticity) occurs in up to half of the more severely affected children, and many of these children require major…
- Trial name
- POPPIES (NCT01437644)
- Testing
- botulinum toxin intramuscular injection
- Where
- United Kingdom
- Volunteers
- 54 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Cancer, Pain
PECBLOCK for the Treatment of Pain After Breast Surgery
Pain after breast cancer surgery could be severe and about 1/3 of patients will develop chronic pain. The PECBLOCK is the injection of local anesthetics between the two pectoral muscles to block pectoral nerves and intercostal…
- Trial name
- PECBLOC (NCT01670448)
- Testing
- PECBLOCK under echoguidance
- Where
- 2 sites in Canada, France
- Volunteers
- 128 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Chronic Postoperative Pain
Help With Early Detection of Postoperative Neuropathic Pain Using SMS After Ambulatory Surgery
Chronic post-operative pain is generally defined by persistent pain more than 2 months after surgery. General reviews on chronic post-operative pain describe an overall incidence of 30%, of which 5 to 10% are described as severe.
- Trial name
- SMS DPpostop (NCT04313855)
- Testing
- SMS in the early detection of postoperative neuropathic pain
- Where
- France
- Volunteers
- 306 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Breast Cancer
Paravertebral Block and Reduction in Opioid Consumption After Mastectomy
This prospective randomized study evaluates the efficacy of paravertebral block in reducing opioid consumption during mastectomy and its impact on acute and chronic postoperative pain.
- Trial name
- BPV-MAST (NCT07817797)
- Testing
- Paravertebral Block, Multimodal Analgesia
- Where
- Tunisia
- Volunteers
- 40 people
- Sponsor
- University Tunis El Manar