Clinical trials: Pain, Chronic Post-Surgical
Chronic Postoperative Pain
Dexmedetomidine for Prevention of Chronic Postoperative Pain
Chronic postoperative pain (CPSP) is common symptom in patients after surgery, seriously affected the quality of life. Accumulating evidences have demonstrated dexmedetomidine can improve chronic pain.
- Trial name
- NCT03275207
- Testing
- saline, dexmedetomidine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhongda Hospital
Postoperative Pain, Opioid Use
SPSIP Block Versus ESP Block for Chronic Pain After Unilateral Breast Surgery
This prospective, randomized, assessor-blinded study will compare serratus posterior superior intercostal plane block and erector spinae plane block in adult female patients undergoing unilateral breast surgery.
- Trial name
- SPES-CPSP (NCT07674836)
- Testing
- Serratus Posterior Superior Intercostal Plane Block, Ultrasound-guided Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Engin Çetin
Breast Cancer
Chronic Post Breast Surgery Pain
The purpose of this study is to learn if paravertebral block (PVB) will reduce chronic pain after surgery. Our hypothesis is that chronic pain from breast surgery as a consequence of central sensitization can be prevented by…
- Trial name
- NCT00847067
- Testing
- Paravertebral block
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Cardiac Surgery, Sternotomy
Affecting Factors for Chronic Pain After Sternotomy
Chronic pain is common complication of surgery procedures. Rates of mortalits is getting lower in cardiac surgery. This situation has brought us to focus morbidity and long term life quality.
- Conditions
- Cardiac Surgery, Sternotomy, Pain, Acute, Pain, Chronic
- Trial name
- NCT06534372
- Testing
- Open cardiac surgery with sternotomy
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Ankara Etlik City Hospital
Chronic Pain, Other Functional Disturbances Following Cardiac Surgery
Functional and Anatomical MRI of the Spinal Cord and Peri-spinal Tissues
The current study is an amendment to a previously approved blinded randomized controlled trial (NCT02697812) which examines the rate at which the sternal retraction maneuver is performed during cardiac surgery (standard over 30…
- Trial name
- NCT02925364
- Testing
- magnetic resonance imaging (MRI)
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Dr. Tarit Saha
Lymphedema, Seroma
Breaststroke Swimming After Breast Cancer Treatment/Surgery as a Means of Treatment for Seroma, Lymphedema, and Chronic Arm and Chest Pain
Following surgery and treatment for breast cancer, many patients experience swelling of lymph nodes (lymphedema) or accumulation of fluid (seroma) that can cause pain, restrict movement, and reduce quality of life.
- Conditions
- Lymphedema, Seroma, Pain, Postoperative, Pain, Chest
- Trial name
- NCT04080934
- Testing
- Swimming
- Where
- Canada
- Volunteers
- 128 people
- Sponsor
- Ottawa Hospital Research Institute
Chronic Pain
"Evaluation of the Efficacy of Intravenous Lidocaine on Chronic Post-operative Pain in Patients Requiring Emergency Abdominal Surgery. A Multicentre, Randomised, Controlled, Double-blind Study."
Chronic pain is a major public health issue. According to the most recent sources, it affects around 11 million people in France, leading to a significant deterioration in patients' quality of life, limitations in their…
- Trial name
- LIDOC-POPEYE (NCT07869173)
- Testing
- Lidocain
- Where
- 6 sites in France
- Volunteers
- 266 people
- Sponsor
- Nantes University Hospital
Pain, Postoperative, Chronic Postoperative Pain
Analgesia in Laparoscopic Cholecystectomy
The investigators hypothesis is that perioperative infusion of 0.75 ropivacaine in patients undergoing laparoscopic cholecystectomy may modify the intensity of postoperative pain or the analgesic consumption during the first 24…
- Trial name
- NCT01388946
- Testing
- Ropivacaine 0.75, Normal saline
- Where
- 2 sites in Greece
- Volunteers
- 110 people
- Sponsor
- University of Athens
Pain, Acute, Pain, Postoperative
The Impact of Esmolol Administration on Postoperative Recovery
The aim of this study will be to investigate the effect of a continuous infusion of low dose esmolol on intraoperative and postoperative opioid consumption, as well as on postoperative recovery and chronic pain
- Conditions
- Pain, Acute, Pain, Postoperative, Pain, Chronic Post-Surgical, Esmolol
- Trial name
- esmolol (NCT05567822)
- Testing
- Esmolol Hydrochloride, normal saline
- Where
- Greece
- Volunteers
- 70 people
- Sponsor
- Aretaieion University Hospital
Chronic Pain, Anaesthesia
Comprehensive Pain Programme to Determine Mechanism of Transition of Acute to Chronic Postsurgical Pain
To determine whether central sensitization is a mechanism of CPSP (chronic postsurgical pain) in women who will develop CPSP compared to women with no CPSP after hysterectomy.
- Conditions
- Chronic Pain, Anaesthesia, Genetics Predisposition
- Trial name
- TAHP (NCT02025153)
- Testing
- pain testing
- Where
- Singapore
- Volunteers
- 216 people
- Sponsor
- KK Women's and Children's Hospital
Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease
Post-Market Registry of AURYON Atherectomy Device in Subjects Affected With Infrainguinal Peripheral Artery Disease
The PATHFINDER Registry is a prospective, non-randomized, single arm, multicenter observational study. This pilot registry is aimed to evaluate the performance (peri-procedural) and clinical outcomes (intermediate and long-term)…
- Conditions
- Infrainguinal Peripheral Artery Disease, Peripheral Arterial Disease, PAD
- Trial name
- PATHFINDER (NCT04229563)
- Testing
- AURYON Atherectomy System
- Where
- 10 sites in United States
- Volunteers
- 102 people
- Sponsor
- Angiodynamics, Inc.
Chronic Postoperative Pain
Placebo Effect In Spinal Cord Electrical Stimulation for Pain
Objective: To evaluate if spinal cord stimulation (SCS) performs better than placebo (no stimulation) in the long term to reduce persistent neuropathic leg pain refractory to medication and other conservative treatments in…
- Trial name
- PISCES (NCT06585033)
- Testing
- Spinal cord stimulation
- Where
- 4 sites in Netherlands, Norway and 1 more
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Postoperative Pain, Cesarean Section Surgery
Analysis of the Incidence and Risk Factors of Chronic Pain After Cesarean Section
Persistent postoperative pain is a globally recognized issue that deserves attention. Cesarean section is one of the surgeries that may cause persistent postoperative pain.
- Trial name
- NCT06704490
- Testing
- Cesarean section
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Huazhong University of Science and Technology
Lung Cancer
Acute and Chronic Pain After Video-assisted Thoracoscopic Surgery for Lung Cancer
The aim of this study is to evaluate whether preoperative CT- guided hookwire localization would influence the incidence and intensity of acute and chronic pain after VATS.
- Trial name
- NCT05478460
- Testing
- Hookwire localization
- Where
- China
- Volunteers
- 161 people
- Sponsor
- Fudan University
Surgery
Prediction of Chronic Pain by the Pain Monitor
The skin conductance algesimeter (Pain Monitor™, Med-Storm Innovation AS, NO-0264 Oslo, Norway)) reflects the sympathetic nervous system by the measurement of the skin conductance of the palm of the hand.
- Trial name
- D3C (NCT01595711)
- Testing
- Pain Monitor
- Where
- 2 sites in France
- Volunteers
- 6 people
- Sponsor
- Hopital Foch
Chronic Sinusitis, Postoperative Pain
Opioid-Free Anesthesia in FESS: A Prospective ERAS Study
1. Information for Patients and Families What is this study about? When patients undergo functional endoscopic sinus surgery (FESS), strong pain relievers called opioids are traditionally used during anesthesia.
- Conditions
- Chronic Sinusitis, Postoperative Pain, Postoperative Nausea and Vomiting (PONV), Surgical Field Visibility
- Trial name
- OFA-FESS (NCT07812389)
- Testing
- Dexmedetomidine, Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people
- Sponsor
- Filiz Kaya
Regional Anesthesia, Thoracic Surgery
Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery
The objective of the study is to compare the efficacy of the Serratus Anterior Plane block (SPB) realised in its deep plane, with a multi-holed catheter in place for twenty four hours, to a standard intravenous analgesia for…
- Conditions
- Regional Anesthesia, Thoracic Surgery, Post-operative Pain, Post-operative Chronic Pain
- Trial name
- Serrathos (NCT03277391)
- Testing
- Serratus anterior plane block, patient-controlled analgesia
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Libre de Bruxelles
Breast Cancer, Breast Cancer Female
Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial
The LOLIPOP Trial is a large (n=4,300 patients) pragmatic, international, multicentre, prospective, randomised, double blind, placebo-controlled, parallel assessment, safety and effectiveness superiority study.
- Conditions
- Breast Cancer, Breast Cancer Female, Breast Conserving Surgery, Mastectomy
- Trial name
- LOLIPOP (NCT05072314)
- Testing
- lidocaine 2% and 10%
- Where
- 49 sites in Australia, Hong Kong and 2 more
- Volunteers
- 4,300 people
- Sponsor
- Monash University
Postoperative Delirium, Chronic Postsurgical Pain
Peripheral Blood Single Cell Sequencing Analysis of POD and CPSP in Elderly Patients After Total Knee Arthroplasty
Single-celled sequencing for evaluating differences in gene expression patterns in different cell types of the dynamics of a means of this research as a starting point, to study the postoperative delirium and chronic pain at the…
- Trial name
- NCT05572307
- Where
- China
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Chronic Pain, Cesarean Section Complications
Reducing Chronic Pain Following Cesarean Delivery
This pilot study will evaluate the feasibility and acceptability of delivering Empowered Relief (ER), a single-session pain relief skills class, to postpartum women with ongoing pain and/or pain interference following cesarean…
- Conditions
- Chronic Pain, Cesarean Section Complications, Postpartum
- Trial name
- NCT07799883
- Testing
- Empowered Relief
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University