Clinical trials: Pain, Experimental
Chronic Pelvic Pain
CPP Among Somali Women in Norway: SCED
Chronic pelvic pain (CPP) in women is a condition associated with negative cognitive, behavioral, sexual and emotional consequences.
- Trial name
- NCT07820176
- Testing
- Multimodal physiotherapy
- Where
- Norway
- Volunteers
- 30 people
- Sponsor
- Kristiania University College
Low Back Pain, Compare Pain Modulation Assessments in Pain-free Cohorts
Pain Modulation - Experimental Assessments Using Different Modalities
The goal of this study is to investigate how different painful stimuli are processed and modulated in the nervous system. In various pain conditions, including low back pain, often no specific source can be identified as the…
- Trial name
- NCT04323293
- Testing
- Cold Water Bath, Neutral Water Bath
- Where
- Switzerland
- Volunteers
- 705 people, healthy volunteers welcome
- Sponsor
- Schweinhardt Petra
Pain, Hyperalgesia
Evaluation of the Antihyperalgesic Effect of Tapentadol in Two Human Experimental Models
MOR-NRI like Tapentadol are expected to reduce signs and symptoms of central sensitisation besides effectively reducing pain intensity in pain.
- Conditions
- Pain, Hyperalgesia, Allodynia
- Trial name
- NCT01615510
- Testing
- Tapentadol immediate release
- Where
- Germany
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Pain
Non-pharmacological Pain Management in Term Neonates
A randomised clinical trial in a single centre. This study was performed to compare the effect of white noise, facilitated tucking, and their concerted application during heel-stick sampling on pain in term babies.
- Trial name
- NCT04144543
- Testing
- White Noise, Facilitated Tucking, White Noise+Facilitated Tucking
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Çankırı Karatekin University
Chronic Neck Pain
Effects of Minimally Invasive Techniques in Healthy and Chronic Cervical Pain Individuals
Brief Summary: This project consists of two sequential experimental phases designed to analyze the immediate and 24-hour effects of three invasive physiotherapy techniques -dry needling (DN), percutaneous neuromodulation (PENS)…
- Trial name
- NCT07345793
- Testing
- Dry needling, Percutaneous nerve stimulation, Percutaneous electrolysis
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad Europea de Madrid
Postoperative Pain, Anxiety
Effects of Foot Reflexology on Postoperative Pain, Anxiety, Nausea, and Vomiting Among Patients After Laparoscopic Cholecystectomy
This study aims to evaluate the effect of foot reflexology on pain, anxiety, nausea, and vomiting among patients after laparoscopic cholecystectomy.
- Conditions
- Postoperative Pain, Anxiety, Nausea, Vomiting
- Trial name
- NCT07770295
- Testing
- Foot reflexology
- Where
- Egypt
- Volunteers
- 108 people
- Sponsor
- Ain Shams University
Coronary Angiography (CAG)
Effects of White Noise and Earplugs on Patients' Physiological Parameters, Pain, Comfort and Procedure Satisfaction
Coronary artery disease (CAD) is the leading cause of mortality and morbidity worldwide. Coronary Angiography (CAG) is an invasive method used in the diagnosis and treatment of CAD.
- Trial name
- NCT06725875
- Testing
- White Noise Group, Earplug group
- Volunteers
- 90 people
- Sponsor
- Di̇lek Soylu
Experimental Pain in Healthy Human Subjects
Tonic Pain and Transauricular Vagal Nerve Stimulation
This study aims to explore the effect of burst-taVNS (electric stimulation of the concha cymba) on tonic (capsaicin-induced skin pain) and acute (pressure pain sensitivity) experimental pain and cardioception.
- Trial name
- NCT07325058
- Testing
- taVNS, Earlobe Stimulation
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain After Photorefractive Keratectomy, VAS Will be Used to Assess Pain Postoperative
Assessment of Safety and Efficacy of Gabapentin After Surface Ablation, a Case Control Experimental Study
The current study aims at assessing the efficacy and safety of oral Gabapentin alone versus Diclofenac Potassium drugs for postoperative analgesia in patients undergoing surface ablation.
- Trial name
- NCT06752486
- Testing
- Giving post photorefractive keratectomy for pain relief
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Research Institute of Ophthalmology, Egypt
Transcutaneous Electrical Nerve Stimulation, Blunt Pressure Pain
The Antalgic Effect of Pulse Frequency and Pad Size of TENS on Blunt Pressure Pain
The purpose of this study is to determine the antalgic of surface electrical stimulation with pulse frequencies and pad sizes on blunting pressure pain on healthy human due to various temporal and spatial summations of the…
- Conditions
- Transcutaneous Electrical Nerve Stimulation, Blunt Pressure Pain, Pad Size, Pulse Frequency
- Trial name
- TENS (NCT01999595)
- Testing
- Control TENS, High frequency TENS with large pads, Low frequency TENS with large pads
- Where
- Taiwan
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Chronic Primary Pain
Network-Based vs. Standardized Cognitive Behavioral Therapy in Chronic Primary Pain
Cognitive-behavioral therapy (CBT) has been shown to be an effective treatment for chronic primary pain (CPP), but overall effect sizes are small to moderate.
- Trial name
- NCT06784141
- Testing
- personalized Cognitive Behavior Therapy including third-wave, standardized Cognitive Behavior Therapy including third-wave
- Where
- Germany
- Volunteers
- 75 people
- Sponsor
- Prof. Dr. Julia Glombiewski
Healthy
Apomorphine Effects on Experimental Pain
The aims of this study were to assess the effects of the dopamine agonist apomorphine on experimental pain models in healthy subjects and to explore the possible association between these effects and a common polymorphism within…
- Trial name
- NCT01744964
- Testing
- Apomorphine
- Where
- Israel
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Pain, Esophageal Sensitivity
Esophageal Hypersensitivity Study in Healthy Volunteers
The purpose of the study is to compare sensitivity and sensitization of visceral pain in the esophagus using different pain stimuli
- Trial name
- NCT00711048
- Testing
- AZD1386
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Postoperative Pain
Feasibility Study for Intrathoracic Nerve Stimulation
The purpose of this study is to conduct an early clinical evaluation of safety and feasibility of peripheral nerve stimulation (PNS) of the intercostal nerves using an electrical lead placed in the thoracic cavity as a safe and…
- Trial name
- NCT04066374
- Testing
- Peripheral Nerve Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Cleveland Clinic
Post-operative Situation
Study of a Prototype Software to Help Surgical Patients Manage Their Pain Medication
The experimental medical device is a prototype software. The device comes in the form of a smartphone with a touch interface. The smartphone used to support the software is a commercial smartphone marked CE.
- Trial name
- MORPHEE 2 (NCT05707247)
- Testing
- software
- Where
- France
- Volunteers
- 37 people
- Sponsor
- University Hospital, Strasbourg, France
Endometrial Biopsy
The Effect of Virtual Reality on Anxiety and Pain During Endometrial Biopsy
The aim of this study was to reduce the anxiety and pain felt during endometrial biopsy procedure.
- Trial name
- NCT06180317
- Testing
- Virtual reality
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Pain
Peripheral KV7 Activation for Pain Relief
The goal of this clinical trial is to learn if the drug Flupirtine can safely lower pain when used in tiny amounts directly in the skin.
- Trial name
- NCT06971250
- Testing
- Capsaicin only (7.6 ng), Capsaicin + Flupirtine 0.5 µg, Capsaicin + Flupirtine 1.2 µg
- Where
- Austria
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Stefan Heber
Anxiety, Pain
Effect of Recreational Play Activities on Anxiety in Children Receiving Chemotherapy and Their Parents
This single-group pretest-posttest study evaluated changes in anxiety levels among children undergoing inpatient chemotherapy and their parents following nurse-led recreational play activities.
- Trial name
- NCT07348900
- Testing
- Nurse-Led Recreational Play Activities
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Akdeniz University
Subacromial Pain Syndrome
Empowered Relief and Exercise Rehabilitation for People With Subacromial Shoulder Pain
The goal of this clinical trial is to learn whether a single 2-hour online pain skills session called Empowered Relief can help adults with subacromial shoulder pain who are taking part in a 12-week exercise program.
- Trial name
- PainBehave (NCT07791784)
- Testing
- Empowered Relief, Exercise-Based Rehabilitation
- Where
- 10 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- University College Copenhagen
Pain, Dentin Sensitivity
Effect of an Experimental Gel Containing Copaiba Oil-resin in the Control of Dentin Hypersensitivity
This randomized, single-blind, placebo-controlled clinical trial aims to clinically evaluate the effect of an experimental gel containing copaiba oleo-resin in the control of dentin hypersensitivity (DH) in non-carious cervical…
- Conditions
- Pain, Dentin Sensitivity, Dentin Desensitizing Agents
- Trial name
- NCT06872749
- Testing
- KF2 (Potassium nitrate gel), experimental Copaiba gel
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para