Clinical trials: Pain, Labor
Patent Ductus Arteriosus, Prematurity
Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure
The primary objective is to evaluate the Patent Ductus Arteriosus (PDA) closure rate of early vs. late use of Ibuprofen (Ibu). The investigators believe that early use of Ibu will have a higher PDA closure rate than later use of…
- Trial name
- NCT00833365
- Testing
- Ibuprofen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Analgesia, Obstetrical, Coagulation Defect; Postpartum
IV Ketorolac on Platelet Function Post-Cesarean Delivery
Cesarean delivery has become the most common surgical procedure in the US. Non-steroidal anti-inflammatory drugs (NSAIDs) have been shown to improve the quality of post-cesarean analgesia and markedly reduce opioid consumption.
- Conditions
- Analgesia, Obstetrical, Coagulation Defect; Postpartum, Nonsteroidals (NSAIDs)Toxicity, Postpartum Hemorrhage
- Trial name
- KetoPltAgg (NCT03805607)
- Testing
- Ketorolac Tromethamine 30 MG/ML
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Depression, Postpartum, Labor Pain
CSE v. Epidural for Postpartum Depression
The purpose of this pilot prospective randomized control trial is to compare the initiation of labor epidural analgesia by combined spinal epidural vs. epidural for the influence on risk for postpartum depression symptoms.
- Trial name
- COPE (NCT03022526)
- Testing
- CSE, Epidural, Bupivacaine / fentaNYL
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Grace Lim, MD, MS
Other Obstetric Trauma - Delivered
Safe Delivery Using a Belt on the Belly of Pregnant Woman
Safety of natural, vaginal labor for parturient, fetus and newborn is one of most important goal among obstetricians, midwifes, scientific society all over the world.
- Trial name
- SDB (NCT01566331)
- Testing
- Baby-guardTM
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Padova
Preterm Birth, Pain
Effects of Music Based Intervention (MBI) on Pain Response and Neurodevelopment in Preterm Infants
Pilot prospective randomized, double blinded, controlled study to test effect of music based intervention (MBI) on pain response and neurodevelopment in preterm infants.
- Trial name
- NCT04286269
- Testing
- Music Based Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Labour Pain, Satisfaction
Remifentanil as Intravenous Patient-controlled Analgesia (IVPCA) During Labour
Remifentanil is a ultra short-acting synthetic opioid. It is rapidly metabolized by non-specific blood and tissue esterases. We wanted to investigate the efficacy and safety of remifentanil used as analgesia during labour.
- Conditions
- Labour Pain, Satisfaction, Adverse Effects
- Trial name
- NCT00202722
- Testing
- Remifentanil
- Where
- Norway
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Labour Pain
Non-pharmacological Resources in Assisting Labor
The proposed project will be conducted to evaluate the influence of application resources associated with non-pharmacological during labor for pain relief and accelerated phase of expansion.
- Trial name
- NCT01389128
- Testing
- Non-pharmacological resources, Routine care
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Labor Pain
Programmed Intermittent Epidural Bolus Time Interval and Injection Volume
Studies suggest that administration of maintenance epidural solutions as programmed or automated intermittent boluses, rather than continuous infusions, result in lower bupivacaine consumption, decreased need for manual boluses…
- Trial name
- NCT00417027
- Testing
- Programmed Intermittent Epidural Bolus (PIEB)
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Infant, Newborn, Infant, Premature
Effect of a Vibratory Stimulus on Mitigating Nociception-specific Responses to Skin Puncture in Neonates
The assessment and treatment of pain in neonates remains a challenge. In an effort to improve the quality of care while limiting opioid-related adverse effects, this study aims to determine the efficacy of a non-pharmacological…
- Conditions
- Infant, Newborn, Infant, Premature, Pain Perception, Pain Measurement
- Trial name
- NCT04050384
- Testing
- Baby GentleStick
- Where
- United States
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Lance M Relland, MD, PhD
Post-surgical Ocular Inflammation, Post-surgical Ocular Pain
Study to See How Well an Eye Drop, SURF-201, Works and What Side Effects There Are in Cataract Surgery Subjects
SURF-201 is being studied for the treatment of eye inflammation and pain in people who are undergoing cataract surgery. SURF-201 is an investigational drug (which means the study drug is currently being tested) in the form of a…
- Trial name
- NCT04324359
- Testing
- SURF-201
- Where
- 10 sites in United States
- Volunteers
- 91 people
- Sponsor
- Surface Ophthalmics, Inc.
Anxiety, Pain
Presence of a Companion During Performance of Neuraxial Labor Analgesia
The purpose of the study is to evaluate if maternal anxiety is improved when a parturient gets her choice with regard to the presence of a companion during epidural catheter placement for labor analgesia.
- Conditions
- Anxiety, Pain, Health Knowledge, Attitudes, Practice
- Trial name
- Companion (NCT02982213)
- Testing
- Companion Present
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Northwestern University