Clinical trials: Pain, Medication
Bladder Carcinoma
Gabapentin in Reducing the Need for Pain Medication in Patients With Bladder Cancer Undergoing Radical Cystectomy
This randomized phase II/III trial studies gabapentin in reducing the need for pain medication in patients with bladder cancer undergoing surgery to remove the bladder and nearby tissue and organs.
- Trial name
- NCT02355886
- Testing
- Gabapentin, Questionnaire Administration
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Washington
Analgesic Effect
Interpectoral-pectoserratus Plane Block for Minimally Invasive Aortic Valve Replacement Via Right Anterior Minithoracotomy
The goal of this clinical trial is to evaluate the analgesic effect of locoregional anaesthesia, specifically the interpectoral pectoserratus plane (IPP-PSP) block, in comparison to a placebo (sham block) after Aortic Valve…
- Trial name
- PAINCARE (NCT06369870)
- Testing
- Levobupivacaine Hydrochloride 0.25 % Injectable Solution, Sodium chloride 0.9%
- Where
- Belgium
- Volunteers
- 144 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Pain, Postoperative, Arthroplasty, Replacement, Knee
Reducing Postoperative Side Effect of Pregabalin
The purpose of this study was to determine 1) if pregabalin, when given 37.5 mg twice on the day before surgery, would be effective in reducing the early postoperative side effects including dizziness, nausea, vomiting and…
- Conditions
- Pain, Postoperative, Arthroplasty, Replacement, Knee, Arthroplasty, Replacement, Hip
- Trial name
- NCT04599894
- Testing
- 37.5mg Pregabalin + 75mg Pregabalin, 75mg Pregabalin
- Where
- China
- Volunteers
- 58 people
- Sponsor
- The First Hospital of Jilin University
Anxiety Disorders and Symptoms, Fibromyalgia
The Benefits of Natural Medicine, Vitamin IV Therapy and Supplements: Maintaining Good Health Through Nature
Herbal Medicine is known as the medicinal use of herbal substances as a means of treating different conditions in the human body to ensure that the body remains in optimal health and wellness.
- Conditions
- Anxiety Disorders and Symptoms, Fibromyalgia, Arthritis, Chronic Pain
- Trial name
- NCT05067998
- Testing
- IV Vitamin Infused Therapy Treatment, Herbal medicine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Faith A. Richardson
Focus of Study Pain Knowledge
Contemporary Pain Science Education and Physician Assistant Students
The goal of this clinical trial was to learn whether a pain science education session could improve physician assistant students' understanding of pain and their beliefs about people with persistent pain.
- Trial name
- NCT07735663
- Testing
- Pain education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Belmont University
Cancer Pain, Analgesic Drugs
Adequacy of Pain Treatment in Radiotherapy
Aim of the study is to evaluate adequacy of pain treatment in oncologic patients, accessing to Radiotherapy Unit
- Trial name
- NCT03550599
- Testing
- Patients accessing to Radiotherapy Unit
- Where
- Italy
- Volunteers
- 2,000 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs
Non-steroidal Anti-inflammatory in Cardiac Surgery
Non-steroidal anti-inflammatory drugs (NSAID) are part the multimodal strategy in pain management after surgery. However, major concerns are raised in cardiac surgery given the potential side effects of NSAID with more bleeding…
- Conditions
- Acute Postoperative Pain, Non-steroidal Anti-inflammatory Drugs, Cardiac Surgery, Pain Intensity
- Trial name
- KETOPAIN (NCT06381063)
- Testing
- pain management, ketoprofen
- Where
- France
- Volunteers
- 238 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Chronic Stable Angina
Danhong Injection in the Treatment of Chronic Stable Angina
The purpose of this study is to evaluate the effect of Danhong Injection on the relief of angina with the use of the Seattle Angina Questionnaire among patients with stable angina patients
- Trial name
- NCT01681316
- Testing
- Danhong injection, Standard medical care
- Where
- 31 sites in China
- Volunteers
- 920 people
- Sponsor
- China Academy of Chinese Medical Sciences
Pain, Postoperative
Comparison of Local Anesthetic Dose in PENG Block Performed in Total Hip Replacement Operations
The investigators research was designed as a single-center, prospective, randomized double-blind study. The patients undergoing total hip replacement surgery in Istanbul University Istanbul Medicine Faculty Department of…
- Trial name
- NCT04900116
- Testing
- Bupivacaine HCl 0.5 % in 20 ML Injection, Bupivacaine HCl 0.25 % in 20 ML Injection, Bupivacaine HCl 0.125 % in 20 ML Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Pain, Postoperative, Nerve Block
The Comparison of the Analgesic Efficacy and Hemodynamic Effects of Paravertebral Block Compared With Paravertebral and Intercostal Nerve Block for Thoracotomy in Adults.
Thoracotomy is a surgical procedure associated with severe post operative pain during the first day of surgery and is responsible for prolonged hospital stay, patient dissatisfaction and delayed return to normal activities along…
- Conditions
- Pain, Postoperative, Nerve Block, Thoracotomy
- Trial name
- NCT04715880
- Testing
- Paravertebral block/Intercostal Block (PVB/ICB) group, Paravertebral Block (PVB) group
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aga Khan University Hospital, Pakistan
Inguinal Hernia, Abdominal Wall Muscles
Transversus Abdominis Plane Block and Inguinal Hernia Repair
This prospective, randomized, double blinded, placebo-controlled study is designed to evaluate the postoperative analgesic efficacy of the ultrasound-guided transversus abdominis plane block with ropivacaine 0,75 %, in patients…
- Conditions
- Inguinal Hernia, Abdominal Wall Muscles, Regional Anesthesia, Postoperative Pain
- Trial name
- NCT02030223
- Testing
- Transversus abdominis plane block
- Where
- Greece
- Volunteers
- 59 people
- Sponsor
- Papacharalampous Panagiota
Pain Syndrome, Propofol Infusion Syndrome
Warm Patch Decrease Propofol Injection Pain
Propofol causes injection pain is still a common clinical unsolved problem. Mixing a small amount of lidocaine with propofol or injecting lidocaine in advance can reduce the pain caused by propofol injection.
- Conditions
- Pain Syndrome, Propofol Infusion Syndrome, Injection Site Irritation
- Trial name
- NCT04555980
- Testing
- Warming patch, Cotton patch
- Where
- China
- Volunteers
- 120 people
- Sponsor
- First People's Hospital of Chenzhou
Pain
Comparison of Pain Sensation During Single Use of Two Topical Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Different case reports are showing that depending on the drug used for eye drops, it might provoke a painful sensation. Actually two leading NSAIDs are used in ophthalmology.
- Trial name
- NCT00869219
- Testing
- Nevanac, Acular LS
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Santa Casa de Misericordia de Santos
Pain, Acute, Hip Arthropathy
Safety of Ibuprofen After Major Orthopaedic Surgeries
Safety of an eight-day treatment with ibuprofen after primary hip and knee arthroplasties.
- Conditions
- Pain, Acute, Hip Arthropathy, Knee Arthropathy, Safety Issues
- Trial name
- PERISAFE (NCT05575700)
- Testing
- Ibuprofen
- Where
- 11 sites in Denmark
- Volunteers
- 2,904 people
- Sponsor
- Naestved Hospital
Chronic Migraine, Headache
Efficacy of GONB in Patients of Migraine
The study was carried to determine the analgesic efficacy of greater occipital nerve block in patients of migraine. It was a randomised controlled which took place from april 2022 - october 2022.
- Trial name
- NCT05679765
- Testing
- Greater Occipital Nerve Block with dexamethasone and lidocaine, Greater Occipital Nerve Block with 0.9% saline
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Pain Medicine Department
Neuralgia, Postherpetic
RN624 For Pain Of Post-Herpetic Neuralgia
This study will test the efficacy and safety of two doses levels of RN624 versus placebo for the relief of pain caused by post-herpetic neuralgia (PHN).
- Trial name
- NCT00568321
- Testing
- RN624
- Where
- 31 sites in United States
- Volunteers
- 99 people
- Sponsor
- Pfizer
Spondylolisthesis, Analgesia, Postoperative
Ultrasound-Guided Erector Spinae Plane Block for Postoperative Pain Control in Lumbar Spondylolisthesis Surgery
This clinical trial aims to evaluate the effectiveness of ultrasound-guided erector spinae plane (ESP) block as an adjunct to general anesthesia for managing postoperative pain in patients undergoing lumbar spondylolisthesis…
- Conditions
- Spondylolisthesis, Analgesia, Postoperative, ESPB
- Trial name
- NCT07514806
- Testing
- Control Group: General Anesthesia Without Erector Spinae Plane Block, Intervention Group: General Anesthesia With Ultrasound-Guided Erector Spinae Plane Block
- Where
- Bangladesh
- Volunteers
- 50 people
- Sponsor
- Bangladesh Medical University
Shoulder Pain, Knee Pain
Cryoneurolysis for Knee and Shoulder Pain in an Inpatient Setting
The purpose of the study is to measure the outcomes of a standard care, an ultrasound guided mini-invasive percutaneous procedure, performed on recent stroke patients on reduces pain, increases function \& quality of life The…
- Conditions
- Shoulder Pain, Knee Pain, Spasticity, Pain
- Trial name
- NCT05674604
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Opiate Dependent, Previous Illicit Drug Use
Pupillometry and Pain Thresholds Patients Substituted by Methadone and Buprenorphine
The purpose is to study the relation between pupillary diameter measured under scotopic conditions, and the pain thresholds measured at the time of peak and residual effect of methadone/buprenorphine in opiate-dependent patients…
- Trial name
- PUPIDOL (NCT01560442)
- Testing
- Buprenorphine and Methadone Hydrochloride
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Pain
Effect Study of on Intervention on Pain, Function, Health and Behaviour for Older Adults Living With Chronic Pain
The aim for the study is to examined the effect of an individually tailored integrated behavioral medicine in physiotherapy intervention including functional exercise, for older adults, having chronic musculoskeletal pain, living…
- Trial name
- NCT02953470
- Testing
- Individual tailored functional exercise, Standard care
- Where
- Norway
- Volunteers
- 105 people
- Sponsor
- Oslo Metropolitan University