Clinical trials: Pain, Medication
Infant, Newborn, Diseases
Reduced Infant Response to a Routine Care Procedure After Glucose 25% Analgesia in Comparison to Materna RTF Stage 1
Glucose has analgesic and calming effects in newborns. To date, it is not known whether the beneficial effects extend to care giving procedures that are performed after painful procedures.
- Trial name
- glucose (NCT01514253)
- Testing
- Glucose 25%, Materna RTF Stage 1, Water for Injection
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Acute Pain
Study to Examine Pain Relief With Supplemental Intrathecal Morphine in TKA Patients
This is a prospective, randomized, double-blinded, placebo-controlled study designed to examine pain relief following intrathecal morphine sulfate (0.2mg) in patients undergoing total knee arthroplasty (TKA) under spinal…
- Trial name
- NCT02620631
- Testing
- Morphine
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Stony Brook University
Pain, Postoperative, Postoperative Nausea and Vomiting
Dexamethasone for Post-cesarean Delivery Pain
The purpose of this study is to compare post-cesarean section consumption of pain medication between two groups of patients undergoing scheduled cesarean section at term gestation who receive a single-dose of intraoperative…
- Trial name
- NCT01812057
- Testing
- Dexamethasone
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- Duke University
Fractured Neck of Femur, Postoperative Pain
Postoperative Analgesia for Fractured Neck of Femur With Periarticular Infiltration of Local Anaesthetic
The purpose of this study is to determine that periarticular levobupivacaine infiltration after surgical fixation of fractured neck of femur will improve the early postoperative pain sensation.
- Trial name
- NCT02057601
- Testing
- Levobupivacaine infiltration group
- Where
- Ireland
- Volunteers
- 37 people
- Sponsor
- Cork University Hospital
Pain
Observational Study on the Patients With Pain Medications
The purpose of this study is to describe the use of pain treatments in Taiwan, the demographics, clinical characteristics of patients requiring pain treatments, current treatments, outcomes of treatments and the reasons for…
- Trial name
- NCT00771212
- Testing
- Observational pain control study
- Volunteers
- 2,636 people
- Sponsor
- Johnson & Johnson Taiwan Ltd
Opioid Use Disorder
Mobile Peer Support for OUD Recovery
The COVID-19 pandemic puts individuals recovering from opioid use disorders (OUDs), an already vulnerable population, at increased risk of overdose due to decreased access to treatment, decreased social support, and increased…
- Trial name
- MPS (NCT05405712)
- Testing
- Mobile Phone App
- Where
- 2 sites in United States
- Volunteers
- 1,300 people
- Sponsor
- Brown University
Cystic Fibrosis, Back Pain
Osteopathic Treatment in Adult Patients With Cystic Fibrosis
To study the contribution of osteopathy on the reduction of pain in adult patients with cystic fibrosis
- Conditions
- Cystic Fibrosis, Back Pain, Neck Pain, Chest Pain
- Trial name
- MUCOSTEO (NCT01293019)
- Testing
- Osteopathic treatment, Usual care
- Where
- France
- Volunteers
- 32 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pain, Acute, Knee Osteoarthritis
Comparison of the Analgesic Effect of Subsartorial Saphenous Block and Popliteal Sciatic vs Subsartorial Saphenous Block and IPACK in Total Knee Replacement Surgery.
Total knee replacement surgery is associated with significant pain in the immediate postoperative period, especially in movement. In turn, this is associated with more subsequent chronic pain.
- Conditions
- Pain, Acute, Knee Osteoarthritis, Anesthesia
- Trial name
- NCT06514365
- Testing
- IPACK block with Bupivacaine 0.25% with adrenaline
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- Germans Trias i Pujol Hospital
Inguinal Lymph Nodes Enlarged
The Analgesic Efficacy of Ultrasound Guided Transversalis Fascia Plane Block in Inguinal Lymph Node Dissection
Pain accompanying Inguinal lymph node dissection triggers a complex stress response leading to impairment of pulmonary, immunological and metabolic function.
- Trial name
- NCT07331129
- Testing
- transversalis fascia plane block and surgical sit local anesthetic infiltration
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Post Operative Pain, Acute
Comparison Between the Analgesic Effect of Fascia Transversalis Block vs Caudal Block
Despite the growing interest in interfascial blocks and their successful use in pediatric surgeries, no previous randomized clinical trials have directly compared the analgesic efficacy, opioid-sparing effect, and safety profile…
- Trial name
- NCT07235475
- Testing
- Caudal Block Anesthesia, Fascia Transversalis Block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Opioid Use, Unspecified
Effect of Opioid Shortage on Drug Selection
This study will look at the effects of fentanyl shortage in laparoscopic cholecystectomy cases. The opioid shortage, specifically hydromorphone and fentanyl, caused a decrease in administration of opioid analgesia for…
- Trial name
- NCT04099030
- Where
- United States
- Volunteers
- 1,668 people
- Sponsor
- Wake Forest University Health Sciences
Pain Control After Elective Hepatectomy
Epidural Versus Paravertebral Block Analgesia After Hepatectomy
The best mode of analgesia delivery after hepatectomy is currently unknown. Many institutions routinely use continuous epidural analgesia (CEA) for pain control in this patient population.
- Trial name
- NCT02909322
- Testing
- Bupivacaine and Hydromorphone, Ropivacaine and Hydromorphone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Dr. Anthony Ho
Postoperative Pain, Acute, Anaesthetic
Analgesic Effect of Intraoperative Intravenous S-Ketamine During Total Knee Arthroplasty Surgery
Severe acute pain after total knee arthroplasty surgery has multiple implications for hospitals and patients, monopolising resources and affecting the quality of life.
- Trial name
- NCT05289050
- Testing
- sodium chloride (NaCl; 0.9%), S-ketamine
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Ling Dong
Breast Cancer, Postoperative Pain
Preoperative Sleep Quality and Postoperative Outcomes in Breast Surgery
Brief Summary: This prospective, single-center observational study examined the association between preoperative sleep quality and postoperative outcomes in women undergoing elective breast cancer surgery.
- Conditions
- Breast Cancer, Postoperative Pain, Inflammation
- Trial name
- NCT07547774
- Testing
- Preoperative Sleep Quality Assessment (PSQI)
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
General Anesthetic Drug Adverse Reaction
Effect of Tegileridine Versus Sufentanil as Analgesic Components on Opioid-Induced Cough During Anesthesia Induction
In patients undergoing general anesthesia with planned tracheal intubation , a prospective, randomized, controlled study was conducted to record the occurrence of cough 2 minutes after injection of Sufentanil or Tegilerdine.
- Trial name
- NCT07323043
- Testing
- Tegilerdine, Sufentanil
- Where
- China
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- The First People's Hospital of Lianyungang
Effect of Drug
Efficacy of Trypsin-Chymotrypsin On Post-operative Pain After Single Visit Root Canal Treatment
Achieving effective pain control after endodontic treatment is still a disruptive event to all the clinicians. There is a knowledge gap regarding the effect of protease on postoperative pain following root canal treatment…
- Trial name
- NCT05479747
- Testing
- post operative analgesics
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Anesthesia
Comparison of Analgesic Effect of Volatile Anesthetics
The purpose of this clinical trial is to compare analgesic effect of sevoflurane and desflurane at equal minimum alveolar concentrations using surgical pleth index.
- Trial name
- NCT02830243
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangbuk Samsung Hospital
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Pain, Intractable
Efficacy and Safety of Ultra-low Dose Methadone as Adjuvant Analgesic in Cancer Patients With Pain
The research hypothesis of this study is: In patients with moderate to severe cancer related pain, the addition of low dose methadone to an existing opioid significantly reduces pain severity compared to low doses morphine.
- Trial name
- UDOME (NCT02687347)
- Testing
- oral methadone, oral morphine
- Where
- Canada
- Volunteers
- 204 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pain, Postoperative, Shoulder Joint Disorder
Intravenous Dexmedetomidine, Dexamethasone and Interscalene Block Duration After Arthroscopic Shoulder Surgery
In this single-centre, double-blinded, randomized controlled superiority trial, 189 participants having outpatient, arthroscopic shoulder surgery will be randomized into 3 equal sized groups.
- Conditions
- Pain, Postoperative, Shoulder Joint Disorder, Ambulatory Surgical Procedures, Brachial Plexus Block
- Trial name
- NCT03270033
- Testing
- Dexamethasone, Dexmedetomidine
- Where
- Canada
- Volunteers
- 198 people
- Sponsor
- University of Manitoba
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.