Clinical trials: Pain, Medication
Chronic Low Back Pain
PF-06372865 In Subjects With Chronic Low Back Pain
PF-06372865 In Subjects With Chronic Low Back Pain
- Trial name
- NCT02262754
- Testing
- PF-06372865, Naproxen
- Where
- 46 sites in United States
- Volunteers
- 302 people
- Sponsor
- Pfizer
Acute Radicular Back Pain, Cannabis
Effect of Cannabis Extract on Acute Radicular Pain and on Analgesic Requirement
Clinical evidence about the effects of cannabis in the management of acute pain is rather scarce, mostly consisting of case report-based opinions on adverse events during or after general anesthesia after smoking cannabis…
- Trial name
- NCT04816994
- Testing
- Single-dose of cannabis oil, Control
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Cancer, Pain
Pro-self Pain Management in Norway
The main aim of this study is to evaluate whether a patient education programme on cancer pain management compared to standard care decreases pain and increases patients quality of life.
- Trial name
- Pro-self (NCT00760305)
- Testing
- Pro self pain control programme
- Where
- Norway
- Volunteers
- 167 people
- Sponsor
- Oslo University Hospital
Postoperative Pain
Dexmedetomidine in Erector Spinae Block in Postoperative Analgesia
60 female patients scheduled for breast cancer surgeries, allocated in 3 groups for erector spinae block with bupivacaine and erector spinae block with dexmedetomidine added to bupivacaine and control group.
- Trial name
- NCT04920669
- Testing
- erector spinae block with bupivacaine, erector spinae block with bupivacaine + dexmedetomidine
- Where
- Egypt
- Volunteers
- 58 people
- Sponsor
- Mohamed Elsayed Hassan
Irreversible Pulpitis
Analgesic Effect of Anahil and Ibuprofen on Pain After Root Canal Therapy in Patients With Pulpitis of the Molars in Qazvin(a City in Iran)
Hypothesis: 0: The analgesic effect of Ibuprofen and Anahil would be the same in reducing the pain after root canal therapy. 1: Ibuprofen shows higher potency to reduce the pain after root canal therapy.
- Trial name
- NCT05349929
- Testing
- Gelofen (generic name of Ibuprofen in Iran), Anahil ( generic name of Bromelain in Iran), Root Canal Therapy
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Qazvin University Of Medical Sciences
Pain
Evaluation of the Analgesic Effect of Music Therapy in Critically Ill Patients During Potentially Painful Nursing Procedures: a Pilot Study
Pain is a common problem encountered in about 60 % of critically ill patients who can communicate. Its occurrence can be related to several causes, mainly dominated by invasive procedures.
- Trial name
- Painkiller (NCT02883959)
- Testing
- music therapy
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Versailles Hospital
Fentanyl Analgesia
Analgesic Effect and Plasma Concentration of Epidural Versus Intravenous Fentanyl
CONTEXT AND OBJECTIVE: Controversies exist regarding the site of action of Fentanyl after epidural injection. The objective of this investigation was to compare the analgesic effect of epidural and intravenous Fentanyl for lower…
- Trial name
- FTN (NCT00635986)
- Testing
- Fentanyl
- Volunteers
- 30 people
- Sponsor
- Federal University of São Paulo
Radius Fracture Distal, Pain, Postoperative
Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation
This randomized controlled trial will test the hypothesis that patients receiving an intraoperative auricular acupuncture protocol will require less postoperative opioid analgesic use compared to those who do not receive…
- Trial name
- NCT05974254
- Testing
- Acupuncture
- Where
- United States
- Sponsor
- Baylor College of Medicine
Postoperative Pain, Shoulder Pain
Comparative Efficacy of Buprenorphine Transdermal Patch Versus Tramadol in Postoperative Analgesia for Shoulder Arthroscopy
This study compares the efficacy, safety, and patient satisfaction of the Buprenorphine 10 mg transdermal patch versus Tramadol for postoperative analgesia in shoulder arthroscopic surgery.
- Conditions
- Postoperative Pain, Shoulder Pain, Opioid Analgesia, Tramadol
- Trial name
- NCT06742554
- Testing
- Buprenorphine transdermal patch, Tramadol
- Where
- Saudi Arabia
- Volunteers
- 70 people
- Sponsor
- medina medical center
Pain, Fracture of Neck of Femur
TRAUMEEL for Pain After Fracture of Neck of Femur
We hypothesize that Traumeel S is more effective than placebo in reducing 48-hour mean cumulative morphine consumption in patients scheduled for surgical correction of fracture of neck of hip.
- Trial name
- NCT00307905
- Testing
- Traumeel S
- Where
- Israel
- Volunteers
- 224 people
- Sponsor
- Shaare Zedek Medical Center
Stable Angina, Unstable Angina
Drug Coated Balloon Compared to Bare Metal Stent for de Novo Coronary Artery Lesions
This randomized trial will assess the efficacy of Drug Coated Balloon (DCB) compared to Bare Metal Stent (BMS) using Fractional Flow Reserve (FFR) guidance for de novo coronary artery lesions in patients unable to tolerate dual…
- Trial name
- NCT02456402
- Testing
- Drug Coated Balloon, Bare Metal Stent
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Ulsan University Hospital
Post Operative Pain, Bradycardia
Postoperative Analgesic Effectiveness of Bupivacaine With and Without Dexmedetomidine in Patients With Abdominal Surgery
Abdominal surgeries are major surgical procedures that are performed at any teaching hospital. Pain control is major concern in the intra-operative as well as post-operative period in these patients.
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Nausea
- Trial name
- NCT06531603
- Testing
- bupivacaine wound infilteration, Bupivacaine plus dexmedetomidine wound infilteration
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Sahiwal medical college sahiwal
Pain
Effect of Topical and Oral Diclofenac on Pain Related to Intravitreal Injections
The analgestic efffect of Diclofenac Sodium 0.1% Eye Drops and a combination of Diclofenac Sodium 0.1% Eye Drops and oral Diclofenac Sodium sustained-release 75mg tablets on pain related to intravitreal injections will be…
- Trial name
- NCT02837770
- Testing
- Diclofenac Eye Drops, Pacebo pill, Oral Diclofenac
- Where
- Greece
- Volunteers
- 76 people
- Sponsor
- University Hospital of Patras
Inguinal Hernia Unilateral, Pain Management
Comparing Opioids Vs NSAIDs for Postoperative Pain Management in Unilateral Primary Open Inguinal Hernia Repair
To control post-operative pain, multiple drugs are available, and in the western countries opioids are preferred. However, they have their own side effects, and so to reduce their dependence, multiple adjuncts are used.
- Trial name
- NCT06608056
- Testing
- Pain management after surgery
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Pakistan Air Force (PAF) Hospital Islamabad
Stable Angina
Comparison of Vascular Remodeling Between Different Antianginal Medication Evaluated by Noninvasive ECG-gated Fundus Photographic Evaluation
Treatments for stable angina includes drug therapy such as calcium-channel blocker, beta blocker, and ACEI/ARB. To obtain good prognosis in patients with coronary artery disease,preventing or correcting the progression of…
- Trial name
- NCT01162902
- Testing
- Diltiazem treated group, Bisoprolol treated group, Candesartan treated group
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Seoul National University Hospital
Pain, Abuse, Drug
Age-dependent Effects of Smoked and Oral Delta-9-THC
This study will assess the age-dependent effects of smoked and oral THC on abuse liability, intoxication, analgesia and impairment as a function of age.
- Conditions
- Pain, Abuse, Drug, Intoxication; Cannabinoids
- Trial name
- SAGE (NCT05865470)
- Testing
- Cannabis, Dronabinol
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Erector Spinae Block Analgesia
Aalgesic Efficacy of Erector -Spinae Technique With Levobupvicaine in Patients Undergoing Upper Abdominal Cancer Surgery
To study analgesic efficacy \&safety of bilateral erector spinae block for upper abdominal cancer surgery as apart of multimodal analgesia.
- Trial name
- NCT04315454
- Testing
- Levobupivacaine
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- South Egypt Cancer Institute
Post Operative Pain, Opioid Analgesic Adverse Reaction
Postoperative Analgesia Intervention With Non-opioid Alternatives (PAIN-Alt) Trial - Breast Surgery
North America is experiencing a crisis of opioid use and abuse, partially caused by excessive prescribing by doctors. People often receive their first opioid prescription for pain treatment after outpatient breast surgery (i.e.…
- Conditions
- Post Operative Pain, Opioid Analgesic Adverse Reaction, Surgery, Postoperative Pain
- Trial name
- PAIN-Alt (NCT06507345)
- Testing
- Opioid Analgesia (OA) [Multimodal analgesia including opioid drugs], Opioid-Free Analgesia (OFA) [Multimodal analgesia not including opioid drugs]
- Where
- Canada
- Volunteers
- 540 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Chronic Non-Cancer Pain, Opioid Use Disorder
Long-Term Opioid Therapy in Chronic Non-Cancer Pain: Risks and Benefits
The study investigates long-term opioid treatment in patients with chronic non-cancer pain (CNCP). The study aims to prospectively identify predictive factors for work ability and for developing opioid use disorder (according to…
- Trial name
- NCT06063902
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Uppsala University
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