Clinical trials: Pain, Medication
Fibromyalgia
Complementary and Alternative Medicine (CAM) for Fibromyalgia
This study is an acceptability and feasibility study of two adjunctive interventions: group education with stretching; and group acupuncture.
- Trial name
- NCT02053090
- Testing
- Group Education and Stretching, Group Acupuncture
- Where
- United States
- Volunteers
- 431 people
- Sponsor
- Oregon Health and Science University
Chronic Severe Pain
A Non-interventional, Observational Study for Quality of Life (Overall Health Assessment) in Patients With Chronic Severe Pain During Targinact® Treatment
This non-interventional, observational study evaluates the efficacy of Targinact with regard to quality of life in daily clinical practice in Belgium compared to the previous analgesic treatment.
- Trial name
- NCT01710917
- Testing
- Targinact® (oxycodon/naloxon)
- Where
- Belgium
- Volunteers
- 1,800 people
- Sponsor
- Mundipharma CVA
Rib Fracture Multiple, Pain, Chest
RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe)
Traumatic rib fractures (RF) are a relatively common occurrence in patients of all ages, with a 10% incidence in all trauma patients and are associated with significant morbidity and mortality.
- Conditions
- Rib Fracture Multiple, Pain, Chest, Pain, Acute, Respiratory Failure
- Trial name
- RIB PAIN (NCT03770208)
- Testing
- Intervention: Lidocaine
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Western University, Canada
Pregnancy Related
Clitoris Potential Analgesic Function Research by Pregnant Women : Feasibility Study
Assessment of the acceptability by pregnant women on the research of the potential analgesic function of the clitoris.
- Trial name
- FAC (NCT04257318)
- Testing
- Vibrating Relaxation Tool
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Chemotherapy-induced Peripheral Neuropathy
Neural and Immune Correlates of CIPN and Possible Analgesic Effect of Non-invasive Motor Cortex Stimulation
Over half of cancer patients receiving common chemotherapy treatments experience painful nerve damage called chemotherapy-induced peripheral neuropathy (CIPN).
- Trial name
- NIBS4CIPN (NCT06522685)
- Testing
- transcranial direct current stimulation Soterix REMOTE 1x1 miniCT
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Morgan State University
Postoperative Pain
Quadratus Lumborum Block vs Intrathecal Morphine for Post-Cesarean Analgesia
İn this study, planned to compare the post-operative analgesic efficacy of Intrathecal Morphine Administration and anterior Quadratus lumborum Block in elective cesarean section operations.
- Trial name
- NCT06612424
- Testing
- ANTERİOR QUADRATUS LUMBORUM BLOCK, İNTRATECHAL MORPHİNE GROUP
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Nerve Block
Opioid-Free Pain Management After NUSS Surgery in Adolescents
The investigators applied ultrasound-guided bilateral transverse thoracic fascia block combined with intercostal nerve block-a previously unreported analgesic approach for post-thoracic surgery-to NUSS patients.
- Trial name
- NCT07288424
- Testing
- Nerve block
- Where
- China
- Volunteers
- 17 people
- Sponsor
- Qin Zhang
Renal Calculus
Comparison Between Tramadol Hcl and Other Analgesics in the Treatment of Renal Colic
The purpose of this study is to determine whether Tramadol Hcl is as effective as Voltaren a non-steroidal antiinflammatory drug, and Dipyrone in amelioration of the pain caused by acute renal colic.
- Trial name
- NCT00310908
- Testing
- Tramadol Hcl
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hadassah Medical Organization
More Effective Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination, More Prolonged Duration of Postoperative Analgesia After Modified Radical Mastectomy With Better Drug Combination
Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pec 11 Modified Block on Postoperative Pain Control in Patients Undergoing Breast Surgery
in our study we are trying to reach to the preferred adjuvant from either ketamine or dexmedetomidine to be added to bupivacaine local anesthetic during pec 11 modified block as regard its efficacy and duration of postoperative…
- Trial name
- NCT04380168
- Testing
- Modified pec11 trunk block
- Where
- Egypt
- Volunteers
- 5 people
- Sponsor
- Ain Shams University
Stable Angina, Ischemic Heart Disease
Drug Coated Balloon for Side Branch Treatment vs. Conventional Approach in True Bifurcation Coronary Disease: PRO-DAVID
Bifurcation lesions (BL) on coronary arteries account for 15-20 % of all performed percutaneous coronary interventions (PCI). Preferred approach for treatment of most bifurcation lesions is the stepwise provisional stent strategy…
- Conditions
- Stable Angina, Ischemic Heart Disease, Coronary Artery Disease, Unstable Angina
- Trial name
- PRO-DAVID (NCT04403048)
- Testing
- Provisional DCB approach PCI procedure, Standard provisional approach PCI procedure
- Volunteers
- 800 people
- Sponsor
- Clinical Hospital Center Rijeka
Postoperative Pain
Sacral Erector Spinae Plane Block Effect on Post-Hemorrhoidectomy Pain
Hemorrhoids are commonly observed surgical conditions affecting the anorectal area, characterized by symptoms such as pain, bleeding, and the presence of a protruding mass from the anal opening.
- Trial name
- NCT05965674
- Testing
- Sacral Erector Spinae Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Konya City Hospital
Labor Pain
VPIA Remifentanil for Labour Pain to Reduce Maternal Desaturation and Improve Analgesic Titration
This study is a prospective cohort study aiming to evaluate an improved VPIA remifentanil algorithm which would benefit labouring mothers who are unable or unwilling to receive epidural analgesia
- Trial name
- NCT02733835
- Testing
- Remifentanil
- Where
- Singapore
- Volunteers
- 25 people
- Sponsor
- KK Women's and Children's Hospital
Osteoarthritis, Knee, Osteoarthritis, Hip
Study Of "Continuous Use" Of Celecoxib Vs. "Usual or Intermittent Use"
To determine whether "continuous use" of celecoxib over a 6-month period is more efficacious than "usual or intermittent use" in preventing spontaneous osteoarthritis flares of the knee and hip.
- Trial name
- NCT00139776
- Testing
- Celecoxib
- Where
- 124 sites in United States, Belgium and 6 more
- Volunteers
- 875 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Dexmedetomidine, Fascia Iliaca Block
Effect of Different Administration Routes of Dexmedetomidine Combined with Ultrasound-Guided Fascia Iliaca Block on Emergence Agitation After Hip Replacement Surgery
To examine the impact of various administration routes of dexmedetomidine in conjunction with ultrasound-guided fascia iliaca block (FIB) on emergence agitation (EA) during the postoperative recovery period after hip replacement…
- Trial name
- NCT06614010
- Testing
- Dexmedetomidine Injection, Ropivacaine and Dexmedetomidine, Sodium Chloride Injection
- Where
- China
- Volunteers
- 207 people
- Sponsor
- Qianfoshan Hospital
Children, Inguinal Hernia
Tamadol Wound Infiltration in Children Under Inguinal Hernioplasty
Tramadol is a centrally acting analgesic, is primarily Indicated for the treatment of acute pain, moderate to severe. The hernioplasty in children is an outpatient procedure, and the possibility of postoperative analgesia with…
- Trial name
- NCT01943760
- Testing
- tramadol, 0.9% saline
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of São Paulo
Cancers, Pain, Lower Back Pain
Open-Label Extension to Evaluate the Long-Term Safety, Tolerability and Analgesic Efficacy
The purpose of this study is to evaluate the long-term safety and tolerability of oxymorphone ER as an analgesic in cancer and lower back pain subjects having chronic moderate to severe pain.
- Trial name
- NCT00904280
- Testing
- Oxymorphone ER
- Where
- United States
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Chronic Coronary Syndrome, Stable Angina
Effectiveness and Tolerability of Trimetazidine 80mg Once Daily in Patients With Chronic Coronary Syndrome: The V-GOOD Study
The objective of this non-interventional multicentric study (NIS) is to investigate the efficacy and tolerability of treatment with Vastarel Caps LP® in symptomatic patients with angina over 3 months under conditions of daily…
- Trial name
- V-GOOD (NCT06464276)
- Testing
- No intervention
- Where
- Brazil
- Volunteers
- 800 people
- Sponsor
- Ministry of Health, Brazil
Taxane, Drug-related Side Effects and Adverse Reactions
Exploratory Study on the Use of Pregabalin for the Treatment of Taxol Related Arthralgia-Myalgia
Paclitaxel is chemotherapeutic agent used in many of the most common anti-cancer regimens. Its use is frequently associated with moderate to severe muscle and joint pain that may persist for several days after the treatment.
- Conditions
- Taxane, Drug-related Side Effects and Adverse Reactions, Pain, Breast Cancer
- Trial name
- NCT02024568
- Testing
- Pregabalin
- Where
- Israel
- Volunteers
- 38 people
- Sponsor
- Assaf-Harofeh Medical Center
Arthroscopic Shoulder Surgery
Comparison of the Analgesic Effects of Catheter-Based Versus Single-Shot Serratus Posterior Superior Intercostal Plane Block in Arthroscopic Shoulder Surgery
Patients undergoing arthroscopic shoulder surgery often experience moderate to severe postoperative pain. Various medical treatments are employed to provide analgesia for these patients.
- Trial name
- NCT06826846
- Testing
- Serratus posterior superior intercostal plane block (single-shot), Serratus posterior superior intercostal plane block (catheter-based intermittent bolus)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Pacemaker Implantation, Pain
Effect of Local Anesthetic EMLA (Lidocaine 2.5% and Prilocaine 2.5%) Cream and Reduction in Dose, Pain and Intravenous Analgesic During Permanent Pacemaker Implantation
The investigators believe that the local anesthetic EMLA (Lidocaine 2.5% and Prilocaine 2.5%) cream will lessen pain and reduce the need for anesthesia and analgesia, when implanting a permanent pacemaker.
- Trial name
- NCT02016976
- Testing
- EMLA Analgesic Cream, Dormicum 2.5 mg and Pethidine 25 mg
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Hillel Yaffe Medical Center
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