Clinical trials: Pain, Musculoskeletal
Degenerative Joint Disease of Knee, Rheumatoid Arthritis
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Degenerative knee joint diseases are characterized by chronic pain, inflammation, and functional impairment. In these conditions, mast cell density in the synovial membrane is increased, resulting in an excessive release of…
- Trial name
- NCT07680101
- Testing
- Adelmidrol 2% / Hyaluronic Acid 1%, micronized Palmitoylethanolamide (mPEA) 300mg + ultramicronized Palmitoylethanolamide (umPEA) 600mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
Low Back Pain, Low Back Pain, Recurrent
Structural White and Gray Matter Correlates of Impaired Muscle Control and Deficient Pain Processing
Although the cause of persistent non-specific low back pain (LBP) remains unknown, structural and functional alterations of the brain, alterations in the lumbar muscles and dysfunction of the central nervous system have been…
- Conditions
- Low Back Pain, Low Back Pain, Recurrent, Low Back Pain, Chronic, Healthy Volunteers
- Trial name
- B~Maps (NCT06143319)
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Ghent
Shoulder Pain
Impact of Anthropometrics Data and of Physical Activity Level in Closed kineTic Chain Upper Extremity Stability Test
The purpose of this study is to evaluate impact of anthropometric criteria to CKCUEST score.
- Trial name
- EPOLTEST (NCT04090632)
- Testing
- Closed Kinetic Chain Upper Extremity Stability Test
- Where
- France
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Osteoarthritis, Knee, Osteo Arthritis Knee
Safety and Pharmacodynamics of GNSC-001 Intra-articular Injection for Knee Osteoarthritis
The goal of this clinical study is to determine if a single injection of 1 or more dose levels of adeno-associated virus (AAV) gene therapy (GNSC-001) is safe and tolerated compared to placebo in participants with painful…
- Conditions
- Osteoarthritis, Knee, Osteo Arthritis Knee, Knee Osteoarthritis
- Trial name
- DONATELLO (NCT05835895)
- Testing
- GNSC-001, transient immune-modulation
- Where
- 9 sites in United States
- Volunteers
- 67 people
- Sponsor
- Genascence Corporation
Osteoarthritis, Knee
Detecting Auricular Points in KOA by a Novel APD
This is a pilot diagnostic accuracy study conducted to assess the diagnostic ability of a novel APD for auricular point detection among patients with knee osteoarthritis (KOA), as compared with an already commercialized device.
- Trial name
- APD-KOA (NCT03702699)
- Testing
- Auricular point detector
- Where
- Hong Kong
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Patellofemoral Pain
Effects of Hip and Ankle Mobility Rehabilitation in Male Collegiate Athletes With Patellofemoral Pain
This study evaluates whether a 6-week hip- and ankle-mobility-based rehabilitation program can improve pain, knee-related function, neuromuscular coordination, and physical performance in male soccer players with patellofemoral…
- Trial name
- NCT07542236
- Testing
- Hip- and Ankle-Mobility-Based Rehabilitation Program
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Beijing Sport University
Rotator Cuff Syndrome, Rotator Cuff Injury
Effect Of Sleeping Posture Guidance On Sleep Quality In Patients With Rotator Cuff Syndrome
This study investigates sleep quality in patients with Rotator Cuff Syndrome (RCS) undergoing physical therapy treatment. Existing literature presents a gap regarding longitudinal studies evaluating the impact of physical therapy…
- Conditions
- Rotator Cuff Syndrome, Rotator Cuff Injury, Sleep Disorder (Disorder)
- Trial name
- NCT07376811
- Testing
- Physical Therapy, Physical Therapy + Sleep Guidance
- Where
- Brazil
- Volunteers
- 64 people
- Sponsor
- Federal University of São Paulo
Lumbar Disc Herniation
QLB vs mTLIP for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle with the goal of anesthetizing the thoracolumbar nerves.
- Trial name
- NCT05217121
- Testing
- Quadratus Lumborum Block, Modified-thoracolumbar interfascial plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Fibromyalgia, PRESSURE PAIN THRESHOLD
The Effect of Connective Tissue Massage on Pressure Pain Threshold in Fibromyalgia
The aim of this randomized controlled study is to investigate the immediate effect of connective tissue massage (CTM) on the pressure pain threshold (PPT) in women with fibromyalgia.
- Trial name
- NCT07791134
- Testing
- Connective Tissue Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Ankara Yildirim Beyazıt University
Muscle Spasm; Back Pain
Evaluation of Eperisone HCl in the Treatment of Acute Musculoskeletal Spasm Associated With Low Back Pain - A Double Blind, Randomised, Placebo Controlled Clinical Trial
The purpose of this study is to evaluate the efficacy of Eperisone HCl in the treatment of Acute Musculoskeletal spasm associated with Low-Back Pain.
- Trial name
- NCT00327730
- Testing
- Eperisone
- Where
- 4 sites in India
- Volunteers
- 240 people
- Sponsor
- Eisai Inc.
Knee Osteoarthritis
The Effect of Postoperative "Peanut Ball" Rehabilitation After Total Knee Replacement.
The purpose of this randomized controlled study is to evaluate the effect of postoperative exercise with a "peanut ball" after total knee replacement, on pain, intake of pain killers, knee function, and health-related quality of…
- Trial name
- NCT05137834
- Testing
- Exercise
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Region Skane
Plantar Fasciitis, Heel Spur Syndrome
Effects of Myofascial Trigger Point Dry Cupping on Plantar Heel Pain
The main aim of this study is to investigate the effects of dry cupping on calf muscle trigger points in patients with plantar heel pain.
- Conditions
- Plantar Fasciitis, Heel Spur Syndrome, Chronic Plantar Fasciitis
- Trial name
- NCT02895698
- Testing
- Dry cupping, Stretching exercises
- Volunteers
- 70 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Musculoskeletal Pain
Signal Relief Patch in Musculoskeletal Pain
assess the efficacy of the Signal Relief patch for the management of general musculoskeletal pain
- Trial name
- NCT05288114
- Testing
- Signal Relief Patch
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Signal Relief
Musculoskeletal Pain, Neuropathic Pain
Virtual Reality (VR) Self-Hypnosis Software
This single-site study of self-hypnosis software using an off-the-shelf virtual reality (VR) device (OculusGo™) to determine the software's safety, usability, and preliminary efficacy in pain relief for HIV-associated chronic…
- Conditions
- Musculoskeletal Pain, Neuropathic Pain, Neuralgia
- Trial name
- NCT06398847
- Testing
- Virtual Reality headset
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Pre-eclampsia or Eclampsia With Pre-existing Hypertension
Evaluation of a Physical Therapy Protocol on Quality of Life Musculoskeletal Pain and Anxiety in Women With Preeclampsia
The purpose of this study is to verify that the implementation of a protocol physiotherapy musculoskeletal pain and reduces anxiety and improves quality of life in patients hospitalized at the clinic of high-risk pregnancies at…
- Trial name
- NCT01925508
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo
Breast Carcinoma, Cancer Survivor
Survivorship Care in Reducing Symptoms in Young Adult Cancer Survivors
This randomized clinical trial studies survivorship care in reducing symptoms in young adult cancer survivors. Survivorship care programs that identify the needs of young adult cancer survivors and ways to support them through…
- Conditions
- Breast Carcinoma, Cancer Survivor, Depression, Fatigue
- Trial name
- NCT02192333
- Testing
- Management of Therapy Complications, Quality-of-Life Assessment, Questionnaire Administration
- Where
- 6 sites in United States
- Volunteers
- 390 people
- Sponsor
- Fred Hutchinson Cancer Center
Osteoarthritis, Pain
From Perception to Performance: A Comprehensive Evaluation in Knee Osteoarthritis.
Knee Osteoarthritis (KOA) is commonly characterized by joint pain, swelling, stiffness, and a reduction in range of motion. These symptoms significantly affect daily activities and overall quality of life.
- Conditions
- Osteoarthritis, Pain, Function, Knee Joint Arthritis
- Trial name
- NCT07417033
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Lokman Hekim University
Radius Fracture Distal, Surgery
Volar Locking Plate Versus External Fixation for Distal Radius Fracture - a Longterm Follow up
A 10-year follow up of a fusion of two earlier published randomized controlled trials. 203 patients with displaced distal radius fractures were randomized to surgery with a volar locking plate or external fixation.
- Conditions
- Radius Fracture Distal, Surgery, Surgery--Complications, Treatment Complication
- Trial name
- EXTEND (NCT05371938)
- Testing
- Volar locking plate, external fixation
- Where
- Sweden
- Volunteers
- 203 people
- Sponsor
- Olof Skoldenberg
Fibromyalgia
The Clinical Effect of Low-Intensity Electromagnetic Field Neurostimulation in Fibromyalgia Syndrome Patients
The purpose of this study is to determine whether persons treated with a low-intensity, noninvasive form of cortical electrical stimulation experience a reduction in symptoms of fibromyalgia different than persons receiving a…
- Trial name
- NCT01180244
- Testing
- Noninvasive cortical electrical stimulation
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- McLaren Regional Medical Center
Cervical Pain, Posterior, Musculoskeletal Disorder of the Neck
Investigation of the Immediate Effect of IASTM on Some Parameters in E-Sports Players
Due to the nature of competitive sports, frequent and regular training by e-sports players to increase their performance provides e-athletes with success in the field, but it also increases the time spent in front of the screen.
- Conditions
- Cervical Pain, Posterior, Musculoskeletal Disorder of the Neck, Neck Pain, Posture
- Trial name
- IASTM (NCT07006363)
- Testing
- IASTM
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
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