Clinical trials: Pain, Musculoskeletal
Frozen Shoulder
The Combined Effect of Mulligan Mobilization, Pain Neuroscience-Based Training, and Core Stabilization Exercises in Frozen Shoulder Patients
The purpose of this randomized controlled study is to investigate the effects of a combined rehabilitation program consisting of Mulligan Mobilization with Movement (MWM), Pain Neuroscience Education (PNE), and core stabilization…
- Trial name
- NCT07667556
- Testing
- Pain Neuroscience Education (PNE), Mulligan Mobilization With Movement (MWM), Core Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Yeditepe University
Periodontal Disease, Chronic Neck Pain
Association Between Periodontal Disease and Chronic Neck Pain
This study investigates whether there is an association between periodontal disease (gum disease) and chronic neck pain and related functional disability.
- Trial name
- NCT07711431
- Where
- Turkey (Türkiye)
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Chronic Pain, Functional Limitations
Pain Evaluation and Treatment in Clinical Settings
This new research projet in pain is enrolled into an international official collaboration between researchers and clinicians from Irmandade da Santa Casa de Londrina (ISCAL) and those from two Quebec universities: University of…
- Conditions
- Chronic Pain, Functional Limitations, Musculoskeletal Disorders
- Trial name
- NCT05197777
- Testing
- tDCS associated to functional activities, Conservative physiotherapy
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Rubens da Silva
Chronic Pain, Juvenile Idiopathic Arthritis
Turkish Validity and Reliability of Pain Catastrophizing Scale-Child (PCS-C)
Perception of chronic pain and related disability; occurs through the interaction of physiological and psychological processes. Pain catastrophizing is a cognitive attribution style characterized by a negative mindset and…
- Trial name
- NCT05436301
- Testing
- Pain Catastrophizing Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Lumbar Disc Herniation
Impact of Transforaminal Epidural Steroid Injection in Lumbar Disc Prolpse on Micro RNA-155 Serum Level
Chronic pain could be considered a brain disease as it can affect multiple aspects of brain function, chemistry, neural networks and structure. Pain is associated with impaired cognitive function (1).
- Trial name
- NCT05626283
- Testing
- transforaminal epidural injection., micro RNA-155 serum level
- Where
- Egypt
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Fibromyalgia, Insomnia
Sleep and Pain Interventions in Women With Fibromyalgia
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia.
- Conditions
- Fibromyalgia, Insomnia, Chronic Widespread Pain
- Trial name
- SPIN-II (NCT03744156)
- Testing
- Cognitive Behavioral Treatment-Insomnia, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Missouri-Columbia
Medial Tibial Stress Syndrome
Effect of Shortwave Diathermy and Therapeutic Ultrasound on Medial Tibial Stress Syndrome Among Military Cadets
Medial tibial stress syndrome (MTSS) also known as shin splints or tibial periostitis is a common injury in athletes and soldiers/cadets with incidences ranging between 4% and 35% in these populations .
- Trial name
- NCT04292795
- Testing
- Therapeutic Ultrasound, Short wave diathermy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Shifa Clinical Research Center
Patellofemoral Pain Syndrome
Validity and Reliability of Autocad Software Assessment of JPS in PFPS
The overall aim of the study is to assess the reliability and validity of Autocad software to measure JPS in PFPS, especially: 1.
- Trial name
- NCT03685812
- Testing
- Autocad software
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Cairo University
Low Back Pain
Comparative Effectiveness Study for Surgery vs. Non-Surgery in Patients With Low Back Pain
Purpose: Comparative effectiveness research (CER) between surgical and non-surgical treatment for patients with low back pain Hypothesis: There will be significant differences in surgical and non-surgical treatment effect in…
- Trial name
- CES_SNS_LBP (NCT02883569)
- Testing
- open or endoscopic discectomy, epidural block, exercise
- Where
- South Korea
- Volunteers
- 1,102 people
- Sponsor
- Seoul National University Hospital
Healthy Volunteers, Muscle Fatigue
Effects of Recoverben® on Recovery After Exhaustive Exercise
The aim of the study is to investigate a pre and post workout supplementation (15 days) with Recoverben® , a Aloysia citriodora extract on recovery after exhaustive exercise.
- Conditions
- Healthy Volunteers, Muscle Fatigue, Muscle Soreness
- Trial name
- NCT02923102
- Testing
- Aloysia citriodora extract, Maltodextrin
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Vital Solutions GmbH
Osteoarthritis
A Study of Orthotic Shoe Inserts for Controlling Osteoarthritic Knee Pain
Osteoarthritis is a degenerative joint disease and is the most common form of arthritis. This study will evaluate the effectiveness of customized shoe inserts in controlling and relieving the pain of knee osteoarthritis.
- Trial name
- NCT00076453
- Testing
- Lateral wedge orthotic shoe inserts, Standard orthotic shoe inserts
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Ankle and Hindfoot Arthrodesis
Long-term Safety and Effectiveness of AUGMENT® Injectable Bone Graft Compared to Autologous Bone Graft
The objective of this long-term study is to evaluate the long-term effectiveness and safety of AUGMENT® Injectable Bone Graft vs. autologous bone graft.
- Trial name
- NCT03998137
- Testing
- AUGMENT® Injectable Bone Graft, Standard of Care
- Volunteers
- 94 people
- Sponsor
- BioMimetic Therapeutics
Pain, Persistent Pain
Is Low-load Resistance Training With Blood Flow Restriction More Effective Than Traditional Rehabilitation of Military Personnel With Lower Limb Injuries
Pain can be one of the primary limiting factors to progress following musculoskeletal injury and may be caused by trauma or degenerative changes.
- Conditions
- Pain, Persistent Pain, Musculoskeletal Pain
- Trial name
- LIMITLESS (NCT06621953)
- Testing
- BFR, control group
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- Defence Medical Rehabilitation Centre, UK
Arthritis, Osteoarthritis
Tanezumab in Osteoarthritis of the Knee
Test the efficacy and safety of 3 doses in Osteoarthritis of the knee in patients.
- Trial name
- NCT00733902
- Testing
- tanezumab
- Where
- 82 sites in United States
- Volunteers
- 697 people
- Sponsor
- Pfizer
Myofascial Pain Dysfunction Syndrome, Myofascial Pelvic Pain Syndrome
Precise AI-Controlled Radiofrequency Versus Biofeedback-Electrical Stimulation in Women With Myofascial Pelvic Pain Syndrome: A Comparative Study
Study Summary: Comparison of Two Treatments for Female Myofascial Pelvic Pain Syndrome The goal of this study is to compare two treatment methods-precise AI-controlled radiofrequency therapy versus biofeedback combined with…
- Trial name
- NCT07791277
- Testing
- Intervention 1：Precision AI Temperature-Controlled Radiofrequency, Intervention 2:Biofeedback Combined with Electrical Stimulation
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Jiangxi Women and Children's Medical Center
Musculoskeletal Pain
Efficacy and Safety of the Combination of Ketoprofen and Cyclobenzaprine and Caffeine in Osteomuscular Treatment
The purpose of this study is to evaluate the safety and efficacy of an association with one anti-inflammatory and one muscle relaxant plus caffeine compared to one anti-inflammatory plus caffeine in the treatment of osteomuscular…
- Trial name
- NCT02862977
- Testing
- ketoprofen and cyclobenzaprine association with caffeine, Cyclobenzaprine with caffeine
- Where
- 6 sites in Brazil
- Volunteers
- 414 people
- Sponsor
- EMS
Shoulder Pain
Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene Block
The standard hospital procedure calls for the patient to undergo Interscalene block under ultrasound with or without nerve stimulation guidance prior to going to operating room (OR).
- Trial name
- TIVA (NCT02469961)
- Testing
- Dexmedetomidine, Propofol, Interscalene block
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Maimonides Medical Center
Musculoskeletal Pain
Can a Digital Tooll Facilitate Shared Decision-making and Increase Self-efficacy in Vocational Rehabilitation?
The study investigates both the effects and the experienced value of the mobile application, MIRA, which is a combination of an electronic diary, a dialogue tool and a decision support tool.
- Trial name
- NCT04695002
- Testing
- MIRA, Control
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Region MidtJylland Denmark
Fibromyalgia (FM)
Cannabis Extract in Fibromyalgia Syndrome - the SUNRISE Study
The aim of this observational study is to evaluate the effects of cannabis extract Avextra 10/10 solution on pain, fatigue, sleep, and quality of life among patients affected by fibromyalgia (FM) syndrome.
- Trial name
- SUNRISE (NCT06747039)
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Hamstring Tightness, Myofascial Pain
The Effects of Soft Tissue Therapy and Exercise on Hamstring Tightness
The purpose of this study is to investigate the effects of myofascial decompression (cupping) and neurodynamic sliding technique for the hamstring on Division I Track and Field athletes who complain of hamstring tightness.
- Conditions
- Hamstring Tightness, Myofascial Pain, Musculoskeletal Pain
- Trial name
- NCT03651141
- Testing
- Neurodynamic Sliding, Myofascial Decompression, Diathermy
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Oklahoma State University
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