Clinical trials: Pain, Musculoskeletal
Diabetes Mellitus Type 2, Breast Neoplasms
AI-Based Phenome Data Analysis for Predicting the Onset of Major Diseases
This study aims to develop and validate an artificial intelligence (AI)-based predictive model to estimate the risk of incident onset of five major diseases or conditions: cardiovascular disease, type 2 diabetes mellitus, breast…
- Conditions
- Diabetes Mellitus Type 2, Breast Neoplasms, Low Back Pain, Osteoarthritis
- Trial name
- NCT07595718
- Where
- South Korea
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Jae Yong Jeon, MD
Adhesive Capsulitis
Education-based Physical Therapy Approach for Adhesive Capsulitis
This study aims, by means of a randomized control trial, to investigate which treatment method (corticoid injection + physiotherapy with a focus on manual therapy and home-exercises versus corticosteroid injection + physiotherapy…
- Trial name
- NCT03245476
- Testing
- Physical therapy focus on manual therapy and home-exercises, Physical therapy focus on education and supported home exercises
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Hasselt University
Osteoarthritis of the Knee
A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee Marching On for Veterans With Osteoarthritis of the Knee
Knee osteoarthritis (KOA) is one of the most common and disabling conditions among Veterans. Management of KOA is challenging as there are few effective treatments other than joint replacement.
- Trial name
- MOVE-OK (NCT05035810)
- Testing
- Social Incentives and Gamification to Promote Exercise, Corticosteroid Injection given in A-B order, No Social Incentive applied
- Where
- 4 sites in United States
- Volunteers
- 221 people
- Sponsor
- VA Office of Research and Development
Chronic Pelvic Pain, Interstitial Cystitis
Effect of Repetitive Transcranial Direct Current Stimulation (tDCS) on Chronic Pelvic Pain
We will rigorously test whether modulation of the motor cortex by transcranial direct current stimulation (tDCS) is an effective treatment for patients with chronic pelvic pain through the following specific aims: A) The primary…
- Conditions
- Chronic Pelvic Pain, Interstitial Cystitis, Post Traumatic Stress Disorder, Fibromyalgia
- Trial name
- NCT00554320
- Testing
- tDCS
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Summa Health System
Degenerative Joint Disease of Shoulder
Cryoneurolysis of the Suprascapular Nerve for Perioperative Pain Control After Receiving a Reverse Total Shoulder Arthroplasty (RTSA)
The main purpose of this research is to find out if a treatment called cryoneurolysis can reduce pain after reverse total shoulder replacement surgery. This treatment uses cold to temporarily block a nerve in the shoulder.
- Trial name
- NCT07125833
- Testing
- Cryoneurolysis, No cryoneurolysis
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- North Texas Medical Research Institute, PLLC
Fibromyalgia, Irritable Bowel Syndrome
Fecal Calprotectin Levels in Patients With Fibromyalgia
This study was designed to evaluate fecal calprotectin levels in patients with fibromyalgia syndrome. Fecal calprotectin levels from fibromyalgia patients with and without gastrointestinal symptoms as well as healthy controls…
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Abdominal Pain
- Trial name
- NCT05404893
- Testing
- Fecal calprotectin measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ege University
Chronic Pain, Musculoskeletal Diseases
Pain and Health Beliefs in Rehabilitation Outpatients
This cross-sectional study was conducted to investigate the relationships between patients' pain beliefs, health beliefs about complementary and alternative medicine, and levels of spiritual well-being in a Physical Medicine and…
- Trial name
- NCT07199647
- Testing
- Questionnaire Administration
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Gulseren Demir Karakilic
Back Pain
Tapentadol IR vs Oxycodone IR vs Placebo in Acute Pain From Vertebral Compression Fracture Associated With Osteoporosis
The purpose of this study is to determine the effectiveness and safety of tapentadol immediate release (IR) as compared with placebo and oxycodone IR in patients with acute pain caused by vertebral compression fractures (VCF)…
- Trial name
- NCT00771758
- Testing
- oxycodone IR, tapentadol IR
- Where
- 37 sites in United States
- Volunteers
- 108 people
- Sponsor
- Ortho-McNeil Janssen Scientific Affairs, LLC
Developmental Dysplasia of the Hip
Caudal Dexmedetomidine vs Ketamine for Postoperative Analgesia in Pediatric DDH Surgery
This study compares two medicines, Dexmedetomidine and Ketamine, added to caudal Bupivacaine to control pain after hip surgery in children.
- Trial name
- CDK-DDH (NCT07385352)
- Testing
- Dexmedetomidine, Ketamine, Bupivacaine
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- Assiut University
Pain, Trigger Point Pain, Myofascial
Subthreshold Stimulation Versus Suprathreshold Stimulation in People With Chronic Low Neck Pain
this trial will involve three groups. Group 1 will receive subthreshold stimulation. Group 2 will receive suprathreshold stimulation. Group 3 will receive shame treatment.
- Trial name
- NCT06559358
- Testing
- electrical stimulation
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS)
This Study Aimed to Evaluate the Effect of Dynamic Neuromuscular Stabilization (DNS) on Pain Intensity and Functional Disability in Women With PLBP as Common Problem Affect t he Women After Birth Which Often Impacting Their Quality of Life and Ability to Perform Daily Activities
The aim of this study was to determine the effect of DNS on women with post-partum LBP. Post-partum low back pain (PLBP) represents a prevalent and clinically significant condition that adversely impacts mobility, pelvic floor…
- Conditions
- Post -Partum Low Back Pain, Dynamic Neuromuscular Stabilization (DNS), Women's Health / Physiotherapy, Musculoskeletal Rehabilitation
- Trial name
- NCT07099755
- Testing
- Intervention Group: Name: Dynamic Neuromuscular Stabilization (DNS) Exercises, Control Group:Name: Conventional Physiotherapy (Ultrasound and Infrared Therapy)
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gehad Alaa
Arthritis, Rheumatoid
Study in Patients With Moderated to Severe Rheumatoid Arthritis Who Have Failed to Combination Therapy of Conventional Disease-modifying Antirheumatic Drugs (cDMARDs) to cDMARD Plus ANti-TNF Versus cDMARDs in Real World
This study will be conducted to observe the disease activity change of Conventional Disease Modifying Anti-Rheumatic Drugs (cDMARD) plus anti-tumour necrosis factor (anti-TNF) from baseline to 6 months compared with cDMARDs, as…
- Trial name
- HUMAN (NCT03264703)
- Where
- 15 sites in South Korea
- Volunteers
- 212 people
- Sponsor
- Eisai Korea Inc.
Temporomandibular Joint Disorders, Myofascial Pain Syndromes
Post-Isometric Relaxation in Temporomandibular Disorders
This planned randomized, single-blind clinical trial will investigate the effects of adding the Post-Isometric Relaxation (PIR) technique to a standard postural exercise program in individuals with moderate to severe…
- Conditions
- Temporomandibular Joint Disorders, Myofascial Pain Syndromes, Mandibular Dysfunction
- Trial name
- PIR-TMD (NCT07130279)
- Testing
- Postural Exercises + Post-Isometric Relaxation (PIR) Technique, Postural Exercises
- Volunteers
- 40 people
- Sponsor
- Sanem ŞENER
Post-Meniscectomy Pain Syndrome, Osteoarthritis, Knee
The SUN Clinical Trial (Safety Utilizing NUsurface Meniscus Implant)
The NUsurface® Meniscus Implant SUN Clinical Trial is a multi-center, single-arm, prospective, open label, non-randomized, observational clinical trial to gather safety and probable clinical benefit data on the NUsurface®…
- Trial name
- SUN (NCT02483988)
- Testing
- NUsurface® Meniscus Implant
- Where
- 13 sites in United States
- Volunteers
- 115 people
- Sponsor
- Phoenix Kinetics
Revision Spine Surgery, Fusion of Spine
Pre-Operative Ketamine Infusion for Post Operative Pain Control After Revision Spinal Surgery
To determine if a pre-operative ketamine infusion would provide a similar decrease in post-operative analgesic and opioid consumption as intra-operative ketamine, but expand the monitoring period through the post-operative phase…
- Conditions
- Revision Spine Surgery, Fusion of Spine, Cervical Fusion, Lumbar Fusion
- Trial name
- KIPSs (NCT06066879)
- Testing
- Ketamine Hydrochloride
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- AXIS Spine Center- a division of Northwest Specialty Hospital
Osteoarthritis
The Impact of Dietary Restriction of Animal Protein and Fat on Osteoarthritis
Patients will be randomized into the control or intervention group. Based on patient preference, the intervention group will be trained for one hour in either individual or group format on vegan diet.
- Trial name
- NCT01939262
- Testing
- Limitation of Animal Fat and Protein in the Diet, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Sports Physical Therapy
Comparative Effects of Rebound Training and Theraband Resistance Exercise in Badminton Players
Comparative Effects of Rebound Training and Theraband Resistance Exercise in Badminton Players With Patellofemoral Pain Syndrome
- Trial name
- NCT06658288
- Testing
- Rebound Training, Theraband resistance exercise
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
LIPIN1 Deficiency
Acute Rhabdomyolysis and Muscle Pain Associated With Mutations in the LPIN1 Gene - A Retrospective Study Describing the Safety and Efficacy of Hydroxychloroquine Sulfate Given on a Compassionate Basis to Patients Suffering From Lipin-1 Deficiency
Lipin-1 deficiencies are responsible for severe rhabdomyolysis and muscle pain in childhood. A specific treatment does not exist.
- Trial name
- LIPIN-1-METAB (NCT04007562)
- Testing
- Hydroxychloroquine Sulfate
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Pain, Fibromyalgia
Chronic Pain, Couples, & Physical Activity
Chronic pain affects more than 50 million adults in the United States and is estimated to cost the nation more than $560 billion dollars each year.
- Conditions
- Chronic Pain, Fibromyalgia, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04077164
- Testing
- No intervention, observational only.
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Illinois Institute of Technology
Osteoarthritis
Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip
This is a prospective open-label clinical study of 50 patients to determine safety and treatment potential of autologous cell therapy for pain and inflammation associated with Osteoarthritis of the hip.
- Trial name
- NCT02844764
- Testing
- [StroMed + platelet rich plasma (PRP)]
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- VivaTech International, Inc.
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