Clinical trials: Pain, Musculoskeletal
Fibromyalgia
Virtual Reality for Fibromyalgia
Fibromyalgia is a frequent chronic pain syndrome almost often affecting women and associating diffuse chronic musculoskeletal pain (for more than 3 months), fatigue and sleep disturbances.
- Trial name
- VR_Fibro (NCT05567861)
- Where
- Monaco
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Princesse Grace
Low Back Pain, Herniation, Disc
Non-surgical Spinal Decompression Therapy and Outcomes
This project will determine the clinical utility of non-surgical spine decompression for chronic low back pain (LBP). LBP is one of the highest incidence medical conditions that contributes to disability, decreased activities of…
- Conditions
- Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal
- Trial name
- RESTORE (NCT06525896)
- Testing
- NSSD
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of South Florida
Seasonal Influenza, Cough
Safety Study of IV Peramivir in Hospitalized Subjects With Confirmed or Suspected Influenza
This is a Phase 3, open-label, randomized study of the antiviral activity, safety, and tolerability of intravenous Peramivir in hospitalized subjects with confirmed or suspected influenza infection.
- Conditions
- Seasonal Influenza, Cough, Sore Throat, Nasal Congestion
- Trial name
- NCT00957996
- Testing
- Peramivir
- Where
- 110 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- BioCryst Pharmaceuticals
Osteoarthritis of the Shoulder, Osteoarthritis of the Hip
Study to Compare Exposure of TA Following Administration of FX006 or TAcs in Patients With OA of the Shoulder or Hip
This is an open-label study to compare systemic exposure to triamcinolone acetonide following a dose of extended-release FX006 or immediate-release TAcs (triamcinolone acetonide suspension) in patients with osteoarthritis of the…
- Trial name
- NCT03382262
- Testing
- FX006 32 mg, TAcs 40 mg
- Where
- 6 sites in United States
- Volunteers
- 55 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Osteoarthritis
The Impact of Dietary Restriction of Animal Protein and Fat on Osteoarthritis
Patients will be randomized into the control or intervention group. Based on patient preference, the intervention group will be trained for one hour in either individual or group format on vegan diet.
- Trial name
- NCT01939262
- Testing
- Limitation of Animal Fat and Protein in the Diet, Control
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Essentia Health
Patellofemoral Pain Syndrome
The Effects and Predictors of Patella Taping in the Treatment of Patellafemoral Pain Syndrome
Background: Taping has been used for more than 20 years for patellofemoral pain syndrome (PFPS) but the effectiveness is still controversial.
- Trial name
- NCT01727596
- Testing
- taping
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Knee Osteoarthritis
Efficacy of Radial Shockwave Therapy for Treatment of Pain in Knee Osteoarthritis
The objective of this study is to compare the results of 2000 impulses of radius shockwaves per week with 2000 placebo shockwaves on the treatment of pain and functional incapacity of patients with severe primary knee…
- Trial name
- NCT02197962
- Testing
- Extracorporeal Radial shockwaves
- Where
- 2 sites in Brazil
- Volunteers
- 105 people
- Sponsor
- Marta Imamura
Osteopathic Manipulative Treatment
By Potentially Adding a Century Old Therapeutic Measure to Pain Treatment Regimens Called Osteopathic Manipulative Treatment, Can Help Decrease Muscle and Bone Pain and the Usage of Opioid Pain Medication.
Osteopathic Manipulative Treatment (OMT) has been used to successfully treat patients for over a hundred years. Even though there have been many subjective clinical results, there is still little research measuring the actual…
- Trial name
- NCT06930196
- Testing
- Counterstrain, Muscle Energy, High Velocity Low Amplitude
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Skagit Regional Health
Osteoarthritis, Knee
Radiofrequency Ablation on Pain Relief of Knee Osteoarthritis
Introduction Osteoarthritis (OA) is a chronic, progressive disease with high disability and teratogenicity in the joints. Deterioration of the articular cartilage is the main problem associated with osteoarthritis, which…
- Trial name
- NCT05050396
- Testing
- Cooled versus thermocoagulant Radiofrequency Ablation in pain relief of knee osteoarthritis
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Fibromyalgia
Pain Management Techniques for Fibromyalgia
Pain management techniques may influence how the brain processes pain and may help patients with fibromyalgia (FM), a chronic pain condition. This study will train patients with FM to use pain management techniques.
- Trial name
- NCT00086060
- Testing
- Exercise regimen, Relaxation training, Standard Care
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Osteoarthritis, Knee
Effects of Different Collagen Formulations on Knee Osteoarthritis
The purpose of this study is to evaluate and compare the effects of two different collagen supplement formulations on pain, physical function, and overall quality of life in adults with knee osteoarthritis.
- Trial name
- NCT07800780
- Testing
- 10g Hydrolyzed Collagen, 5g Bioactive Collagen Peptide
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Cihangir Türemiş
Osteoarthritis, Knee, Total Knee Arthroplasty
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
This is a prospective randomized controlled trial that will assess preoperative, perioperative, and long-term oxidative stress (OS); pain; and functional outcomes over a 12 month period and test the hypothesis that a potent…
- Conditions
- Osteoarthritis, Knee, Total Knee Arthroplasty, Chronic Postsurgical Pain
- Trial name
- NCT06083480
- Testing
- GlyNAC (combination of glycine and n-acetylcysteine)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Vanderbilt University Medical Center
Knee Osteoarthritis, Knee Pain Chronic
The Effect of PEMF for Patients With Knee OA
Health care costs are increasing alarmingly, which will impose an overwhelming economic burden to an aging society like that of Hong Kong.
- Trial name
- NCT05548712
- Testing
- Pulse Electromagnetic Field
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Enthesitis Related Arthritis (ERA)
A Study of the Efficacy and Safety of Adalimumab in Pediatric Subjects With Enthesitis Related Arthritis
The purpose of this study is to evaluate the efficacy and safety of adalimumab given subcutaneously every other week (eow) as compared to placebo in pediatric subjects with Enthesitis Related Arthritis (ERA).
- Trial name
- NCT01166282
- Testing
- adalimumab
- Volunteers
- 46 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Osteoarthritis
26 Week Open Label Study Evaluating Single IA Injection of DUROLANE SJ for Treatment of Osteoarthritis Pain of the Ankle
26 week open label study of treatment with Durolane for OA pain of the ankle
- Trial name
- NCT02627859
- Testing
- Durolane SJ
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Bioventus LLC
Lumbar Degenerative Disc Disease
Percutaneous Dynamic Stabilization (PDS) System Versus Fusion for Treating Degenerative Disc Disease
The objective of this study is to evaluate the safety and effectiveness of the PDS System compared to the surgical control of posterolateral fusion with autograft and pedicle screw fixation for the treatment of one or two levels…
- Trial name
- NCT00878579
- Testing
- PDS System, Fusion
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Interventional Spine, Inc.
Distal Radius Fracture, Colles Fracture
Wrist Injury Strengthening Exercise (WISE) Versus Usual Care Advice for Improving Pain and Function
The goal of this clinical trial is to find out whether a therapist-guided exercise program helps people aged 50 and older recover better, in terms of pain and function, after a wrist fracture, compared to the usual care advice…
- Conditions
- Distal Radius Fracture, Colles Fracture, Wrist Fracture, Wrist Fractures
- Trial name
- WISE-DK (NCT07538323)
- Testing
- Supervised Exercise, Usual Care
- Where
- Denmark
- Volunteers
- 588 people
- Sponsor
- University of Aarhus
Gut -Microbiota, Inflammation Biomarkers
Dietary Wild Blueberries and Joint Health
The goal of this proposed study is to examine the effects of dietary wild blueberries on gut microbiome, serum markers of inflammation, and joint function in adults.
- Conditions
- Gut -Microbiota, Inflammation Biomarkers, Pain Assessment, Joint Pain
- Trial name
- NCT06828159
- Testing
- Wild blueberry
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nevada, Las Vegas
Musculoskeletal Pain, Low Back Pain
Biotensegrity: Thoracolumbar Fascial Integrity in Chronic Low Back Pain
This is a prospective study on chronic low back pain patients aimed at investigating how findings on a physical examination and musculoskeletal ultrasound may correlate with myofascial damage in the lower back.
- Conditions
- Musculoskeletal Pain, Low Back Pain, Myofascial Pain
- Trial name
- NCT03940313
- Testing
- Prolotherapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- ProloAustin
Temporomandibular Joint Disorders, Temporomandibular Joint Pain
Intra-articular I-PRF Injections in Patients With Temporomandibular Joint Dysfunction
The aim of the study will be to analyze the results of injection treatment in patients diagnosed with temporomandibular joint dysfunction manifested by pain and/or limited jaw mobility.
- Trial name
- NCT05883982
- Testing
- I-PRF injection
- Where
- Poland
- Volunteers
- 51 people
- Sponsor
- Hospital of the Ministry of Interior, Kielce, Poland
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