Clinical trials: Pain, Orofacial, open to volunteers
Myalgia, Muscle Pain
Concentration of Receptors With Affinity for Cannabidiol and Cannabinol and the Effect on Chronic Orofacial Pain of Muscle Origin
The main aim of the presented project will be to examine the concentration of selected receptors (CB1, CB2, TRPV-1) showing affinity for binding to cannabidol (CBD) and cannabinol (CBN) in blood samples collected from people with…
- Conditions
- Myalgia, Muscle Pain, Orofacial Pain, Headache, Tension
- Trial name
- NCT06405646
- Testing
- Blood CB1, CB2, TRPV-1 concentration measurement
- Where
- Poland
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Orofacial Pain, Bruxism
Effectiveness of Chlorzoxazone Versus Orphenadrine Citrate in Alleviating Bruxism Pain
To evaluate the clinical effectiveness of chlorzoxazone in comparison to orphenadrine Citrate in relieving the orofacial pain in bruxers.
- Trial name
- NCT07109882
- Testing
- Chlorzoxazone, Orphenadrine Citrate
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Orthodontic Discomfort, Pain, Orofacial
Comparison of Patient-reported Pain After Initial Archwire Placement
Three different types of 'archwires' can be used in Orthodontic treatment, wire choice is decided by treating Orthodontist based on professional preference since research shows that all types are equally effective.
- Trial name
- Archwires (NCT03906422)
- Testing
- 3M Unitek 0.016 orthodontic archwire, Device: 0.016" Ormco 27oC NiTi orthodontic archwire, Device: 0.016" Ormco 35oC NiTi orthodontic archwire
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Masticatory Myofascial Pain
Effect Of Orofacial Pain Therapy On Bruxism
Bruxism and clenching at night and during the day are considered the most common parafunctions that can influence temporomandibular disorders, including chronic myofascial pain of the masticatory muscles.
- Trial name
- NCT07875738
- Where
- Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Catholic University of the Sacred Heart
Pain, Orofacial
Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain Management
The purpose of this study is to compare the effectiveness of a combined ibuprofen and acetaminophen regimen in controlling discomfort for 4 days after initial orthodontic appliance placement as compared to ibuprofen alone or a…
- Trial name
- NCT04059172
- Testing
- Ibuprofen 200 mg and acetaminphen 650 mg, Ibuprofen 200 mg
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Persistent Idiopathic Facial Pain (PIFP)
Deciphering Persistent Orofacial Pain - PIFP
Persistent non-dental orofacial pain is common yet poorly characterised, and its pathophysiology remains largely unknown. Two clinically similar entities are distinguished: post-traumatic trigeminal neuropathic pain (PTNP), in…
- Trial name
- NCT07791004
- Where
- Germany
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Temporomandibular Disorders (TMD)
Aerobic Physical Activity and Orofacial Myofascial Pain
Orofacial myofascial pain, most commonly represented by Temporomandibular Disorders (TMD) a significant public health, affecting approximately 12% to 14% of the general population.
- Trial name
- AERODOF (NCT07526688)
- Testing
- Temporal Summation of Pain and Questionnaire
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Bruxism, Pelvic Floor Disorder
Bruxism and Pelvic Floor Dysfunction in Young Women
Bruxism and Pelvic Floor Dysfunction in Young Women
- Conditions
- Bruxism, Pelvic Floor Disorder, Young Adult Females, Myofascial Pain Dysfunction Syndrome
- Trial name
- NCT07437924
- Testing
- Questionnaire and Physical Exam
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Orofacial Pain, Sleep Bruxism
Orofacial Pain and Oral Health-Related Quality of Life in Musicians in German Amateur Orchestras
This cross-sectional online survey investigates the prevalence of orofacial pain, sleep-related problems, and oral health-related quality of life (OHRQoL) among adult musicians who play in German amateur orchestras.
- Conditions
- Orofacial Pain, Sleep Bruxism, Oral Health Related Quality of Life (OHRQoL)
- Trial name
- OSQ-MUS (NCT07714837)
- Testing
- Questionaire
- Where
- Germany
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Chronic Masticatory Myofascial Pain
Masticatory Muscle Activity Using a 24-Hour Wearable Device
Patients with chronic masticatory myofascial pain (MFP) often report that stress and parafunctional oral habits aggravate their pain, consistent with the widespread belief that stress and parafunctional habits lead to…
- Trial name
- NCT07861906
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Midwestern University
Mastication Disorder, Fatigue
Validation and Evaluation of the Mastication Function in Adults: The Functional Six-minute Mastication Test (F-6MMT).
Temporomandibular Disorders (TMD) encompass various conditions that affect the temporomandibular joint and associated tissues, often causing or being associated with other symptoms such as jaw pain, myofascial pain, neck pain…
- Conditions
- Mastication Disorder, Fatigue, Temporomandibular Disorder, Orofacial Pain
- Trial name
- F-6MMT (NCT06298786)
- Testing
- Functional 6-minute mastication test
- Where
- 3 sites in Spain
- Volunteers
- 514 people, healthy volunteers welcome
- Sponsor
- Fundació Universitària del Bages
Temporomandibular Disorders (TMDs)
Diagnostic Study Accuracy of Jaw Motion Analyzer(JMA) Versus Research Diagnostic Criteria(RDC/TMD) and Magnetic Resonance Imaging(MRI) for Temporomandibular Disorders Among Patients With Chronic Orofacial Pain.
The goal of this diagnostic accuracy study is to determine the diagnostic accuracy of jaw motion analyzer(JMA) in terms of sensitivity and specificity with target cut of points used by valid reference standards which will be the…
- Trial name
- NCT07486609
- Testing
- The Jaw Motion Analyzer (JMA, Zebris, Germany) as the index test, Research Diagnostic Criteria for Temporomandibular Disoders, Magnetic Resonance Imaging
- Where
- Egypt
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Pain
Emotional Intelligence and Chronic Orofacial Pain
Chronic pain, lasting more than three months, is a widespread health issue that negatively impacts daily life, leading to significant emotional distress and functional impairment.
- Trial name
- IEDOF (NCT07280338)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Myofascial Pain Syndromes, Facial Pain
Comparative Analysis of Dry Needling Techniques for Orofacial Myofascial Pain
This study aims to compare the clinical effectiveness and individual comfort of three distinct dry needling techniques (dynamic, static, and hybrid) for managing orofacial myofascial pain.
- Conditions
- Myofascial Pain Syndromes, Facial Pain, Trigger Points
- Trial name
- NCT07706153
- Testing
- Dry needling
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Flávio Magno Gonçalves