Clinical trials: Pain, Post Surgical
Dental Pulp Necrosis, Pulpitis
Metagenomic Analysis and Postoperative Pain in Infected Root Canals Using Different Irrigation Protocols
Achieving effective root canal disinfection while minimizing postoperative pain is a critical goal in endodontic therapy. Advanced irrigation protocols, such as ultrasonic activation, laser activation, negative pressure…
- Trial name
- NCT07546773
- Testing
- Ultrasonic Irrigation Activation, Laser-Activated Irrigation, Mechanical Irrigation Activation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Suez Canal University
Post Operative Pain
A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl As Additives to Bupivacaine in Pott's Fracture
The aim of this study is to compare the addition of intrathecal dexmedetomidine or fentanyl as adjuvants to hyperbaric bupivacaine in the onset and duration of sensory and motor block, and postoperative analgesia.
- Trial name
- NCT06502262
- Testing
- Bupivacaine Hydrochloride, Fentanyl, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Total Knee Arthroplasty
The Analgesic Effect of Nitroglycerin Patch for Postoperative Pain After Total Knee Replacement
Patients who undergo general anestheesia for total knee arthroplasty pften have sever postoperative pain which hinders their rehabilitation.
- Trial name
- NCT00375362
- Testing
- Nitroderm patch
- Where
- Israel
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Coronary Artery Disease, Myocardial Infarction
Outcome After Coronary Artery Bypass Grafting
The E-CABG registry is a multicenter, European registry collecting data on the preoperative characteristics, treatment strategies and outcome of patients undergoing isolated coronary artery bypass grafting (CABG).
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Angina Pectoris
- Trial name
- E-CABG (NCT02319083)
- Testing
- Coronary artery bypass surgery
- Where
- Finland
- Volunteers
- 4,000 people
- Sponsor
- University of Oulu
Foot, Sleep
Effect of Footbath on Pain Severity and Sleep Quality
The goal of this clinical trial is to examine the effect of hot water foot bath on the patients' pain severity and sleep quality levels on the night of the lumbar degenerative disc surgery.
- Conditions
- Foot, Sleep, Pain
- Trial name
- NCT05658783
- Testing
- Hot water foot bath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Phantom Limb Pain
Treating Phantom Limb Pain Using Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study
When a limb is traumatically severed, pain perceived in the part of the body that no longer exists often develops. This is called "phantom limb" pain, and is different from "stump" pain, which is pain within the part of the limb…
- Trial name
- DoD-PLP-Tx (NCT01824082)
- Testing
- Perineural infusion [continuous peripheral nerve block(s)]
- Where
- 4 sites in United States
- Volunteers
- 144 people
- Sponsor
- University of California, San Diego
Postoperative Pain, Acute
Transversalis Fascia Plane Block for Iliac Bone Graft in Children
The purpose of this study is to determine which method is more effective in postoperative pain control in children undergoing iliac bone grafting for alveoloplasty under general anesthesia: ultrasound-guided transverse abdominal…
- Trial name
- NCT06403462
- Testing
- transversalis fascial plane block, transversus abdominis plane block
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Abdominal Surgery, Postoperative Pain
External Oblique Intercostal Plane Block for Postoperative Analgesia After Major Upper Abdominal Surgery
Postoperative pain after laparoscopic major upper abdominal surgery (e.g., gastric, hepatic, gallbladder, pancreatic surgery) is often severe, and inadequate analgesia may lead to increased opioid use, opioid dependence, and poor…
- Trial name
- NCT07331441
- Testing
- External Oblique Intercostal Plane Block, Standard multimodal analgesia
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Jun Zhang
Adenotonsillectomy, Preoperative Anxiety
Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And Recovery
This study is a prospective, randomized, controlled clinical trial designed to evaluate the optimal timing of midazolam administration in children undergoing adenotonsillectomy.
- Conditions
- Adenotonsillectomy, Preoperative Anxiety, Surgical Stress Response, Postoperative Pain
- Trial name
- Timing-Midazol (NCT07622641)
- Testing
- Midazolam (Oral), Midazolam (Intravenous)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Erzurum City Hospital
Cervical Spine Disease, Pain, Postoperative
Clinical Study on the Safety and Efficacy of the Minimally Invasive Ennovate® Method for Pedicle Screw Placement
The study's main purpose is the collection of clinical data on the patients benefit and safety of pedicle screw placement through an innovative minimally invasive surgical approach compared to the state of the art open surgical…
- Trial name
- MISPEC (NCT06960018)
- Testing
- Ennovate® Cervical, open surgical technique, Ennovate® Cervical, minimal invasive surgical technique
- Where
- 3 sites in Germany
- Volunteers
- 76 people
- Sponsor
- Aesculap AG
Gynecologic Disease, Laparoscopic Surgery
Low-pressure Pulmonary Recruitment Maneuver to Decrease Post-laparoscopic Shoulder Pain in Gynecologic Surgery
Research objective to compare outcomes (shoulder pain score, wound pain score, post-operative residual pneumoperitoneum, lung complication, GI discomfort, administered additional analgesics, time to hospital staying) of using…
- Trial name
- NCT04642118
- Testing
- Pulmonary recruitment maneuver
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Postoperative Pain
Effect of Pectointercostal+ESP Block on Postoperatif Analgesia in Open Heart Surgery
American Society of Anaesthesiologist physical status II-III, aged between 18-65, 60 patients which underwent open cardiac surgery will recruited to this study.
- Trial name
- NCT05590013
- Testing
- Pectointercostal and ESP block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Postoperative Pain
Bilateral Retromuscular Rectus Sheath Block Catheters Usage for Early Postoperative Analgesia After Laparotomic Gastrectomy.
In early postoperative period, the occurrence of severe pain after open major upper GI surgery is a significant issue. The study is aimed to access the efficiency of rectus sheet block with continuous bupivacaine infusion…
- Trial name
- NCT05592496
- Testing
- Bilateral retromuscular rectus sheath block catheters usage for early postoperative analgesia after laparotomic gastrectomy., Catheter insertion technique by using special tube t, Connection of catheters bilateraly to "easy pump" system,
- Where
- 2 sites in Latvia
- Volunteers
- 100 people
- Sponsor
- Riga East Clinical University Hospital
Pain, Acute, Postoperative Pain
Quadratus Lumborum Block vs Erector Spinal Block for Post Abdomen Surgery Analgesia
Prior to surgery, patients will be stratified into groups according to the type of surgical procedure. The anticipated groups are as follows: Patients with colorectal cancer Patients with prostate cancer Patients with renal…
- Conditions
- Pain, Acute, Postoperative Pain, Anesthetics, Local
- Trial name
- NCT05446727
- Testing
- Ropivacaine injection
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Jagiellonian University
Postoperative Pain, Arthroscopic Shoulder Surgery
Comparative Analgesia and Respiratory Effects of Shoulder Blocks
Interscalene block is widely accepted as the gold-standard regional analgesic technique for pain control after arthroscopic shoulder surgery.
- Trial name
- NCT07429669
- Testing
- Interscalene block, Anterior suprascapular block, Pericapsular nerve group (PENG) block
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Pain, Postoperative
Evaluate Analgesic/Sedative Efficacy of Naproxen Sodium and Diphenhydramine in Patients With Postsurgical Dental Pain
The objective of the study is to evaluate the efficacy and safety of a single oral dose of two dose combinations of naproxen sodium and diphenhydramine (DPH) to demonstrate that naproxen sodium/DPH combination provides added…
- Trial name
- Morpheus II (NCT01280591)
- Testing
- Naproxen sodium 440 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 220 mg / DPH 50 mg (BAY98-7111), Naproxen sodium 440 mg (BAYH6689)
- Where
- 2 sites in United States
- Volunteers
- 712 people
- Sponsor
- Bayer
Pain, Postoperative
The Effect of Gabapentin, Ketamine and Dexamethasone on Pain and Opioid Requirements After Hip Surgery
Patients scheduled for primary hip replacement needs postoperative pain treatment, i.e. morphine. Morphine has side-effects: nausea, vomiting, sedation and dizziness.
- Trial name
- NCT00236223
- Testing
- Gabapentin + dexamethasone + ketamine
- Where
- 2 sites in Denmark
- Volunteers
- 48 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Heart Valvular Disease, Minimally Invasive Cardiac Surgery
SPSIP Block and Opioid Use After MICS
This prospective, randomized, controlled, single-center clinical study aims to evaluate the effectiveness of the Serratus Posterior Superior Intercostal Plane Block (SPSIPB) in perioperative pain management among patients…
- Conditions
- Heart Valvular Disease, Minimally Invasive Cardiac Surgery, Postoperative Pain Management, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIPB-MICS (NCT07259824)
- Testing
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara City Hospital Bilkent
Proctological Surgery
Interest in Clonidine in Association With Levobupivacaine Performing a Pudendal Block in Proctological Surgery.
Proctological surgery represents a short duration surgery performed in ambulatory, which causes significant post-operative pain.
- Trial name
- NCT04530903
- Testing
- Clonidine, Levobupivacaine, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Total Hip Arthroplasty (THA)
Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty
The Erector Spinae Plane (ESP) block or spinal erector block was first described in September 2016 by a Canadian team. It's a block that was initially used for the treatment of chronic thoracic neuropathic pain.
- Trial name
- NCT07240961
- Testing
- Lumbal Erector Spinae Plane Block, intravenous pain killers
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- University Tunis El Manar
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