Clinical trials: Pain, Post Surgical
Postoperative Pain
Preemptive and Preventive Acetaminophen/Ibuprofen Fixed-dose Combination After Robot-assisted Radical Prostatectomy
This prospective, randomized, double-blinded study is designed to compare opioid-sparing effect of preemptive and preventive intravenous acetaminophen/ibuprofen fixed-dose combination in patients undergoing robot-assisted radical…
- Trial name
- NCT05685342
- Testing
- Acetaminophen/Ibuprofen fixed-dose combination
- Where
- South Korea
- Volunteers
- 154 people
- Sponsor
- Seoul National University Hospital
Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary
Peritoneal Cavity Conditioning Decreases Pain, Inflammation and Adhesions
Full conditioning of the peritoneal cavity during laparoscopic surgery will decrease post-operative pain, inflammation and adhesion formation.
- Conditions
- Endometriosis of the Cul-de-sac, Chocolate Cyst of Ovary, Fibroid/Myoma (Uterus/Cervix)
- Trial name
- NCT01344486
- Testing
- full conditioning, standard pneumoperitoneum
- Where
- Belgium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Rotator Cuff Tears
Punch vs. Drill Tunnel Use for Anchor Tunnel Creation and Correlation With Post-operative Pain
To determine if different techniques used in the creation of suture anchor socket creation can influence post-op pain following rotator cuff repair.
- Trial name
- Punch/Drill (NCT04288570)
- Testing
- suture anchor socket creation with punch, suture anchor socket creation with drill
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Matt Smith
Postoperative Pain, Shoulder Arthritis
Liposomal Bupivacaine Infiltration vs Continuous Perineural Ropivacaine Infusion for Post-operative Pain After Total Shoulder Arthroplasty
Total shoulder replacement is associated with considerable postoperative pain. A common method to treat and prevent this post operative pain is to place a catheter in the neck and leave it in place for up to 48 hours.
- Trial name
- NCT02787226
- Testing
- Liposomal Bupivacaine Infiltration, Continuous Perineural Ropivicaine Infusion
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Eric Shepard
Cerebral Tumor
The Effects of Gabapentin Premedication on Neurosurgery
The study is to observe the effects of gabapentin premedication on postoperative pain,vomiting and nausea in patients undergoing neurosurgery. 100 neurosurgical patients are randomized into groups gabapentin(GG) or placebo(GP).
- Trial name
- NCT02306278
- Testing
- gabapentin, vitamin capsules
- Where
- China
- Volunteers
- 122 people
- Sponsor
- Capital Medical University
Multimodal Analgesia, Tramadol
Tramadol Versus Morphine for Postoperative Pain Relief Following Laparoscopic Abdominal Surgery
Tramadol is commonly used postoperatively due to its ease of administration, but it carries several risks, including interindividual variability, drug interactions, neuropsychiatric risks in elderly patients, and long-term…
- Conditions
- Multimodal Analgesia, Tramadol, Enhanced Recovery After Surgery, Opioid and Postoperative Pain
- Trial name
- TRAMORNOT (NCT07914335)
- Testing
- Anesthesia induction, Anesthesia maintenance, Multimodal analgesia
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Non-restorable Teeth, Intraoral Surgical Incisions
Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions
This clinical study aims to compare the efficacy of knotless barbed sutures versus N-butyl cyanoacrylate glue tissue adhesive for the closure of intra-oral surgical incisions, with traditional PGA vicryl sutures as a control…
- Conditions
- Non-restorable Teeth, Intraoral Surgical Incisions, Wound Closure, Surgical Tooth Extraction
- Trial name
- KBA vs CA (NCT07491276)
- Testing
- PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Future University in Egypt
Total Knee Arthroplasty, Anterior Cruciate Ligament Reconstruction
Impact of Crutch Type on Gait and Functional Outcomes Post-knee Surgery
Study withdrawn
- Trial name
- NCT04258917
- Testing
- Study withdrawn
- Sponsor
- University of Calgary
Pain, Postoperative, Analgesia
Ultrasound-Guided Bilateral Transversalis Fascia Plane Block With vs Without Dexamethasone for Cesarean Delivery
Cesarean delivery is one of the most frequently performed surgical procedures worldwide, and effective postoperative pain management is essential to facilitate early mobilization, maternal-infant bonding, breastfeeding, and…
- Trial name
- NCT07736989
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Bahçeşehir University
Pain, Postoperative
Comparison of Post-operative Pain Frequency
The objective of this study is: To compare the post-operative pain frequency after single visit root canal versus multiple visit root canal treatment in patients with non-vital teeth Post-operative pain is less frequent after…
- Trial name
- NCT04944589
- Testing
- ROOT CANAL TREATMENT
- Where
- Pakistan
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Fatima Memorial Hospital
Pain, Postoperative
Thoracic Paravertebral Block Using Ropivacaine and Dexmedetomidine
The hypothesis of the study is whether dexmedetomidine plus local anesthetic ropivacaine could extend the pain relieve time compared with only ropivacaine when thoracic paravertebral block is performed at the end of…
- Trial name
- NCT02814890
- Testing
- Video-assisted Pneumonectomy, Thoracic paravertebral block
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Jianghui Xu
Pain, Postoperative
Reducing Opioid Use and Misuse After Wisdom Molar Extractions
Reducing opioid prescription related use and misuse is a major focus for countering the national epidemic of opioid overdose and death.
- Trial name
- NCT04414917
- Testing
- Twin block, iPill dispenser
- Where
- United States
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Cholecystectomy
This prospective, blinded, randomized clinical trial investigates the effect on postoperative pain and nausea, when performing a ventilator-piloted PRM at the end of a laparoscopic cholecystectomy.
- Trial name
- NCT03026543
- Testing
- Pulmonary Recruitment Maneuver, Laparoscopic cholecystectomy, Ventilator
- Where
- Sweden
- Volunteers
- 260 people
- Sponsor
- Region Östergötland
Laparoscopic Cholecystectomy
Venlafaxine for Postoperative Pain of Laparoscopic Cholecystectomy
Recent studies on the impact of perioperative venlafaxine for treatment of acute postoperative pain have yielded positive outcomes .
- Trial name
- NCT05884268
- Testing
- Venlafaxine
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Postoperative Pain, Pediatric Open Heart Surgery
A Combination of Intrathecal Fentanyl and Pecto-Intercostal Fascial Block in Paediatric Cardiac Surgery.
Cardiac surgery is commonly performed via median sternotomy. Patients undergoing cardiac surgical procedures frequently experience intense acute pain in the post-sternotomy wound, which can potentially transition into persistent…
- Trial name
- NCT06882655
- Testing
- PIFB group, Intrathecal fentanyl(IT fentanyl), IT + PIFB
- Where
- 2 sites in Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Postoperative Pain
Effects of Regional Anesthesia Following Mastectomy
Patients of breast surgery dated between April 2016 and March 2021 will be scanned in three groups; solely induced general anesthesia, general anesthesia induced with Erector Spinae Plane Block, and general anesthesia induced…
- Trial name
- NCT05276440
- Volunteers
- 182 people
- Sponsor
- Koc University Hospital
Total Knee Arthroplasty
Dexamethasone in Total Knee Arthroplasty
The purpose of this study is to determine the most efficacious and safest dexamethasone dose given intraoperatively during total knee arthroplasty that reduces postoperative opioid consumption and pain, improves postoperative…
- Trial name
- NCT05018091
- Testing
- Dexamethasone 4mg, Dexamethasone 8 Mg/mL Injectable Suspension, Dexamethasone 16mg
- Where
- 10 sites in United States
- Volunteers
- 438 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Postoperative Pain Management
Assessment of Healthcare Professionals' Knowledge and Attitudes Toward Patient-Controlled Analgesia
Patient-controlled analgesia (PCA) is a widely used method for postoperative pain management that allows patients to self-administer analgesics according to their pain needs.
- Trial name
- NCT07359118
- Testing
- Patient-Controlled Analgesia Educational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Asymptomatic Necrotic Teeth
Effect of Triple Antibiotic Paste as an Intracanal Medication With an Anti-Inflammatory Drug on Post-operative Pain.
The purpose of this study is to determine whether the use of triple antibiotic paste as intracanal medication with an anti-inflammatory drug, compared to a calcium hydroxide will reduce postoperative pain and intracanal bacteria…
- Trial name
- NCT02907489
- Testing
- triple antibiotic paste with an anti-inflammatory drug
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Postoperative
Efficacy of Bupivacain Local Infiltration for the Management of Pain During Cesarean Section
This study aims to evaluate the effect of local administration of bupivacain in the cesarean section incision for postoperative pain control, using the visual analogue pain scale (VAS) and assessing the need for rescue analgesia…
- Trial name
- NCT05404490
- Testing
- Bupivacain
- Where
- Panama
- Volunteers
- 202 people
- Sponsor
- Saint Thomas Hospital, Panama
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