Clinical trials: Pain, Post Surgical
Postsurgical Pain
Multiprofen-CC™ to Reduce Pain After Total Knee Arthroplasty
Total knee arthroplasty is a surgical treatment which involves replacing the damaged articular cartilage of the knee joint with an artificial prosthetic in end-stage knee osteoarthritis.
- Trial name
- MP-TKA (NCT06202989)
- Testing
- Multiprofen-CC™ plus standard treatment
- Where
- Canada
- Volunteers
- 306 people
- Sponsor
- KAZM Pharmaceuticals Inc.
Risk Factors for Post ACL Reconstruction Pain
Risk Factors for Post ACL Reconstruction Pain
In 2006, approximately 130,000 arthroscopic anterior cruciate ligament reconstructions were performed in the United States, and the number is increasing each year.
- Trial name
- NCT05533489
- Testing
- No intervention
- Volunteers
- 924 people
- Sponsor
- Prince of Songkla University
Emergence Delirium, Postoperative Pain
Effect Study of Parecoxib to Treat Emergence Delirium and Postoperative Pain
This prospective, double blind, placebo-controlled, parallel group study will be conducted in three study centers in Guangzhou, China.
- Trial name
- NCT01221025
- Testing
- Parecoxib
- Where
- China
- Volunteers
- 900 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Other Chronic Postoperative Pain
High Pain Intervention in Cesarean Sections
In previous studies the investigators have seen that the severity of pain one day after cesarean delivery can predict the presence of pain and depression 2 months later.
- Trial name
- NCT01298778
- Testing
- Duramorph 150, Acetaminophen, Duramorph 300
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- Wake Forest University Health Sciences
Pain, Postoperative
Toradol v. Celecoxib for Postoperative Pain
Randomized control trial between ketorolac versus celecoxib for postoperative pain following hysterectomy.
- Trial name
- POP (NCT03331315)
- Testing
- Celecoxib, Ketorolac
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Michael Ulm, MD
Postoperative Pain
Effect of Caudal Nalbuphine on Postoperative Analgesia in Children
Nalbuphine as an adjuvant to bupivacaine caudal anesthesia for postoperative analgesia in children undergoing Hypospadias repair. 2 groups, 30 patients each
- Trial name
- NCT02618876
- Testing
- Nalbuphine plus Bupivacaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post Operative Pain, Knee Osteoarthritis
Cryoneurolysis Prior to Total Knee Arthroplasty
Knee osteoarthritis is a major issue worldwide with limited treatment options. Many patients receive knee joint replacement surgery which is considered effective and safe.
- Conditions
- Post Operative Pain, Knee Osteoarthritis, Opioid-Related Disorders
- Trial name
- NCT05840276
- Testing
- Cryoneurolysis
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Hemorrhoidectomy, Hemorrhoids Third Degree
Minimally Invasive Open Excisional Hemorrhoidectomy Compared to Conventional Open Excisional Hemorrhoidectomy: a Clinical Trial
This study aims to demonstrate that open excisional hemorrhoidectomy (OEH), when performed using a minimally invasive approach, results in less postoperative pain and comparable outcomes to conventional OEH.
- Conditions
- Hemorrhoidectomy, Hemorrhoids Third Degree, Hemorrhoidal Disease, Postoperative Pain
- Trial name
- NCT06764849
- Testing
- CONVENTIONAL OPEN EXCISIONAL HEMORRHOIDECTOMY, MINIMALLY INVASIVE OPEN EXCISIONAL HEMORRHOIDECTOMY
- Sponsor
- Hospital Son Llatzer
Postoperative Pain
Surgical Nurses' Pain Management Self-Efficacy and Patients' Postoperative Pain Outcomes
This study examines whether surgical nurses' confidence in managing patients' pain (pain management self-efficacy) is related to how well their patients' pain is managed after surgery.
- Trial name
- NCT07830498
- Testing
- Pain Management Self-Efficacy and Postoperative Pain Outcome Assessment
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 340 people, healthy volunteers welcome
- Sponsor
- Volkan Gokmen
Post-operative Pain, Quality of Life
Post-operative Pain and QoL After RCT
This study is a prospective clinical study, which evaluates pain following the completion of non-surgical root canal treatment and re-treatment cases.
- Trial name
- NCT06412263
- Testing
- Routine root canal treatment/ retreatment
- Where
- United Kingdom
- Volunteers
- 162 people
- Sponsor
- University of Edinburgh
Phantom Limb Pain
Controlled Study of Farabloc for Chronic Phantom Limb Pain Among Veteran Amputees
The primary purpose of this study is to determine if the group using Farabloc shows a greater reduction in pain levels than the group not using Farabloc at 6-week, 12-week and 1-month post treatment follow-ups.
- Trial name
- NCT00797849
- Testing
- Farabloc Limb Cover
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Southern California Institute for Research and Education
Ankle Fracture
Exparel and Ankle Surgery
This study involves a drug called Exparel that has been approved by the US Food and Drug Administration (FDA), for application directly to wound sites. EXPAREL® is a long acting pain reliever.
- Trial name
- NCT02072135
- Testing
- Exparel
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Rutgers, The State University of New Jersey
Kidney Cancer, Prostate Cancer
Effect of Perioperative Intravenous Lidocaine Infusion in Robotic-Assisted Urologic Surgery
Controlling pain is fundamental during and after surgical procedures. This study examines pain associated with robotic assisted surgery on prostate cancer or a kidney mass.
- Trial name
- NCT03824808
- Testing
- Lidocaine Hydrochloride 0.8% in Dextrose 5% Solution, 0.9% Sodium Chloride Injection
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Missouri-Columbia
Pain Management
A Non-invasive Intervention (BreEStim) for Management of Phantom Limb Pain (PLP) After Limb Amputation (Experiment 1)
The purpose of this study is to compare the effectiveness of innovative intervention of breathing controlled electrical stimulation (BreEStim) and conventional electrical stimulation (EStim) in management of neuropathic phantom…
- Trial name
- NCT04750525
- Testing
- BreEStim, EStim
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Periapical Periodontitis, Asymptomatic Irreversible Pulpitis
Effect of Intracanal Cryotherapy on Postoperative Endodontic Pain
This study aimed to evaluate the effects of cooled and room-temperature NaOCl irrigation on postoperative endodontic pain in single-rooted teeth diagnosed with asymptomatic irreversible pulpitis (AIP) or asymptomatic apical…
- Conditions
- Periapical Periodontitis, Asymptomatic Irreversible Pulpitis, Cryotherapy
- Trial name
- NCT07710833
- Testing
- root canal treatment and cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people
- Sponsor
- Recep Tayyip Erdogan University
Postoperative Pain, Thoracic Neoplasms
Erector Spinae Block for Thoracoscopic Surgery
This randomized clinical trial compares the effects of the erector spinae plane block with levobupivacaine and 0,9% saline on postoperative pain intensity, and opioid consumptions following thoracoscopic pulmonary surgery.
- Trial name
- NCT04751552
- Testing
- Erector Spinae Plane Block (for postoperative pain relief)
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- St. Antonius Hospital
Transversus Abdominis Plane Block (TAP Block), Laparoscopic Inguinal Hernia Repair
Spinal Anesthesia Versus General Anesthesia Plus TAP Block for Laparoscopic Inguinal Hernia Repair
This prospective, randomized, double-blind clinical trial compares spinal anesthesia with general anesthesia combined with ultrasound-guided transversus abdominis plane (TAP) block in adult patients undergoing laparoscopic total…
- Trial name
- NCT07866885
- Testing
- General Anesthesia Plus Transversus Abdominis Plane Block, Spinal Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Fatma Cigdem Ozakin
Postoperative Pain
An International Trial to Evaluate the Efficacy and Safety of SABER®-Bupivacaine for Postoperative Pain Control in Patients Following Arthroscopic Shoulder Surgery
The objective is to identify the optimal dose of SABER-Bupivacaine for postoperative pain control in patients undergoing elective arthroscopic shoulder surgery on the basis of pharmacokinetics, efficacy and safety evaluations.
- Trial name
- NCT00993798
- Testing
- SABER-Bupivacaine Treatment 1a, Bupivacaine HCl Treatment 1c, SABER-Bupivacaine Treatment 2a
- Where
- 10 sites in Austria, Germany and 3 more
- Volunteers
- 107 people
- Sponsor
- Durect
Surgery, Pain, Postoperative
Virtual Reality for Postoperative Pain Management
This trial studies an active virtual reality (VR) experience as a means for non-pharmacologic postoperative pain management among patients after head and neck surgery.
- Conditions
- Surgery, Pain, Postoperative, Incision, Otolaryngological Disease
- Trial name
- NCT04464304
- Testing
- Smartphone, Virtual Reality (Oculus Quest)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Pain, Postoperative, Cesarean Section Complications
Satisfaction Following Cesarean Section
Presently, the standard of care at the investigators' practice is that the discharging physician decides the type and amount of opioid medication to prescribe a patient following a cesarean section.
- Conditions
- Pain, Postoperative, Cesarean Section Complications, Postpartum Disorder, Opioid Use
- Trial name
- NCT03355248
- Testing
- Oxycodone Acetaminophen
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ProMedica Health System
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