Clinical trials: Pain, Post Surgical
Total Hip Arthroplasty (THA), Kinesiophobia
Preoperative Video-Based Education in Total Hip Arthroplasty
This single-center, prospective, randomized controlled trial aims to evaluate the effect of preoperative video-based mobilization education on postoperative fear of movement (kinesiophobia), pain during first mobilization, and…
- Conditions
- Total Hip Arthroplasty (THA), Kinesiophobia, Postoperative Pain, Early Mobilization
- Trial name
- NCT07279974
- Testing
- Video-Based Mobilization Education, Standard Verbal Education
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Acibadem University
Unequal Length of Limbs; Congenital, Lower Extremity Deformities, Congenital
Botox Injection for Lower Extremity Lengthening and Deformity Correction Surgery
The purpose of this six site multi-center study is to determine if BTX-A can alleviate the post-operative pain and improve the functional and quality of life outcomes of children with limb length discrepancy or angular deformity…
- Trial name
- BOLLD (NCT00412035)
- Testing
- Botulinum toxin A injection, saline injection
- Where
- 6 sites in United States, Canada
- Volunteers
- 125 people
- Sponsor
- Shriners Hospitals for Children
Urologic Surgical Procedure
Minimizing Post-surgical Pain and Narcotic Administration Through Cryotherapy
Postoperative pain is an unavoidable consequence of open abdominal surgery. Although cryotherapy, the application of ice to a surgical wound site, has been shown to be effective in reducing postoperative pain in orthopedic…
- Trial name
- Ice (NCT01974882)
- Testing
- Ice pack
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Viraj Master
Non-restorable Teeth, Intraoral Surgical Incisions
Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions
This clinical study aims to compare the efficacy of knotless barbed sutures versus N-butyl cyanoacrylate glue tissue adhesive for the closure of intra-oral surgical incisions, with traditional PGA vicryl sutures as a control…
- Conditions
- Non-restorable Teeth, Intraoral Surgical Incisions, Wound Closure, Surgical Tooth Extraction
- Trial name
- KBA vs CA (NCT07491276)
- Testing
- PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Future University in Egypt
Post Operative Pain
Methadone in TKA for Post-op Pain and Opioid Reduction
This randomized, double-blind controlled trial investigates whether intraoperative IV methadone (0.15 mg/kg based on ideal body weight) reduces acute postoperative pain and opioid consumption in patients undergoing elective total…
- Trial name
- NCT07226076
- Testing
- Methadone Hydrochloride
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Medical University of South Carolina
Trigger Point Pain, Myofascial
Trigger Point Incidence After Lumbar Disc Herniation Surgery
Our purpose is to determine the incidence of trigger points in patients who remain in a fixed position for a long time during lumbar disc herniation surgery.
- Trial name
- NCT04136197
- Testing
- Manual palpation for incidence determination
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul University - Cerrahpasa
Pain, Postoperative, Spinal Disease
Comparison of Ultrasound-guided Bilateral ESP Block and Wound Infiltration for Spinal Surgical Analgesia
The aim of our study is to determine the superior procedure in analgesia management by comparing the traditional wound infiltration technique with the ultrasound-guided bilateral erector spina plan block technique in spinal…
- Conditions
- Pain, Postoperative, Spinal Disease, Anesthesia, Local, Anesthesia, Regional
- Trial name
- NCT04642625
- Testing
- Visual Analog Score, patient satisfaction
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Trakya University
Pain, Postoperative, Thoracic Surgery, Video-Assisted
Single Nucleotide Polymorphisms (SNPs) Associated With Postoperative Analgesic Failure
Postoperative pain remains relatively high within 48h for Chinese patients who receive video-assisted thoracoscopic surgery. Different patients experience different pain intensity.
- Conditions
- Pain, Postoperative, Thoracic Surgery, Video-Assisted, Polymorphism, Single Nucleotide
- Trial name
- NCT03916120
- Testing
- Genetic analysis
- Where
- China
- Volunteers
- 198 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain, Postoperative
Acetaminophen vs Placebo for Postoperative Analgesia After Abdominal Surgery
This study investigates whether oral acetaminophen, when added to standard pain management, reduces opioid use and pain after major abdominal surgery, compared to a placebo (inactive pill).
- Trial name
- NCT07720791
- Testing
- Acetaminophen
- Volunteers
- 1,504 people
- Sponsor
- Konya City Hospital
Arthralgia
Study of Viscosupplementation for the Treatment of Knee Pain After Menisectomy
The investigators' objective is to analyze a group of patients who have had a partial meniscectomy but continue to have knee pain after surgery with a double-blind, randomized prospective study comparing the use of Hylan G-F…
- Trial name
- NCT00971074
- Testing
- Hylan G-F 20
- Where
- United States
- Sponsor
- Grant Jones
Other Acute Postoperative Pain
Study of Indomethacin Capsules to Treat Pain Following Bunionectomy
The purpose of this study is to determine whether Indomethacin [Test] Capsules are safe and effective for the treatment of postoperative bunionectomy pain.
- Trial name
- NCT01626118
- Testing
- Indomethacin
- Where
- 4 sites in United States
- Volunteers
- 373 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Cataract
"A Prospective Study of the Efficacy of Intracameral Dexamethasone (Dexycu™) Compared to Standard of Care Treatment for Post-Cataract Surgical Pain and Anterior Chamber Inflammation"
Cataract surgery is the most common surgical procedure performed on humans today. The postoperative regimen includes a combination of steroids, NSAIDs (non-steroidal anti-inflammatory drugs) and antibiotics.
- Trial name
- NCT04781335
- Testing
- Dexycu, Standard of Care post operative eye drops (steroid, antibiotic, NSAID)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- The Eye Institute of West Florida
Postoperative Pain
Study to Evaluate Analgesic Effect of IV Administration of Kappa Agonist CR845 For Hysterectomy Surgery
The primary purpose of this study is to determine if CR845 is effective in treating the pain associated with a laparoscopic hysterectomy.
- Trial name
- NCT01361568
- Testing
- CR845
- Where
- 18 sites in United States
- Volunteers
- 203 people
- Sponsor
- Cara Therapeutics, Inc.
Lumbar Pain Syndrome
Evaluation and Timing in an ERAS-like Structured Rehabilitation Program After Lumbar Spine Surgery
The goal of this clinical trial is to investigate the safety of early inpatient rehabilitation after lumbar spine surgery. Participants are assigned to therapy groups C (low) - A (high) intensity and receive standardized…
- Trial name
- NCT05937997
- Testing
- high intensity physiotherapy, moderate intensity physiotherapy, low intensity physiotherapy
- Where
- Germany
- Volunteers
- 245 people
- Sponsor
- Median
Postoperative Pain, Chronic Pain
Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE).
To assess the effects of prolonged preoperative gabapentin treatment (10 days) on chronic pain after thoracotomy.
- Trial name
- GABATHOMIE (NCT03158376)
- Testing
- Gabapentin
- Where
- France
- Volunteers
- 201 people
- Sponsor
- University Hospital, Lille
Postoperative Pain, Laparoscopic Hysterectomy for Benign Conditions
Randomized Clinical Trial: Effect of an Exercise Routine on Postoperative Shoulder Pain in Laparoscopic Hysterectomy
This is a clinical trial aimed at understanding the impact of a shoulder exercise routine on postoperative shoulder pain in patients who have undergone laparoscopic hysterectomy. Main Questions: 1.
- Trial name
- ERPOSP (NCT06195176)
- Testing
- Shoulder exercises, Hand exercises
- Where
- Mexico
- Volunteers
- 66 people
- Sponsor
- Instituto Nacional de Perinatologia Isidro Espinosa de los Reyes
Neuropathic Pain, Phantom Limb Pain
Mindful SensoriMotor Therapy With Brain Modulation in Highly Impaired Extremities
Brief summary: This single-arm, pilot clinical investigation aims to evaluate Mindful SensoriMotor Therapy (MSMT) enhanced with brain modulation as a treatment of pain due to sensorimotor impairment, such as Phantom Limb Pain…
- Trial name
- NCT04897425
- Testing
- Mindful SensoriMotor Therapy Enhanced with Brain Modulation
- Where
- Sweden
- Volunteers
- 8 people
- Sponsor
- Chalmers University of Technology
Pain, Neuropathic, Amputation Neuroma
Surgical Treatments for Neuroma Pain in Amputees
Amputees often suffer from relentless pain and disability resulting from symptomatic neuromas within the amputation stumps. When conservative measures fail to address these symptoms, two contemporary surgical approaches to treat…
- Conditions
- Pain, Neuropathic, Amputation Neuroma, Phantom Limb Pain
- Trial name
- STOCAP (NCT04204668)
- Testing
- TMR, RPNI, VDMT
- Where
- 2 sites in United States
- Sponsor
- Johns Hopkins University
Postoperative Pain, Intraoperative and Postoperative Opioid Requirements
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of the Relationship Between Intraoperative Intravenous Acetaminophen and Postoperative Opioid Avoidance for Ambulatory Surgical Procedures
This is a research study to determine if giving acetaminophen intravenously in hte operating room will decrease the number of patients who require additional pain medicine, such as morphine, after surgery in the recovery room.
- Trial name
- Cadence (NCT01231191)
- Testing
- Intravenous acetaminophen
- Where
- United States
- Sponsor
- University of California, San Diego
Pain, Postoperative
Post-Caesarean Section Incisional Infiltration With Lidocaine Versus Lidocaine and Epinephrine
Study to compare between efficacy of post-caesarean section infiltration with lidocaine and epinephrine versus lidocaine only to reduce post-incisional pain.
- Trial name
- NCT02274974
- Testing
- Lidocaine, lidocaine and Epinephrine
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
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