Clinical trials: Pain, Postsurgical
Endodontic Inflammation
Evaluation of the Effect of Different Irrigation Activation Methods During Endodontic Retreatment
The persistent and secondary intraradicular infections are the primary causes of post-treatment disease following endodontic treatment of any tooth.
- Trial name
- NCT07779148
- Testing
- Xp Finisher R file
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Minia University
Pain, Chronic Post-Surgical
PERIoperative Holistic RIsk Factor SCreening in the Prevention of Persistent Pain
Assessment and management for improved wellbeing after elective surgery (PERISCOP³E-Care) Diagnostic assessment tool evaluation and cut-off determination for participation in a transmural perioperative care program
- Trial name
- PERISCOPEcare (NCT05526976)
- Testing
- PERISCOPE-care
- Where
- 2 sites in Belgium
- Volunteers
- 660 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Post Operative Pain
Efficacy of Desensitizing Agent,Propolis After an In-office Vital Tooth Bleaching.
This study was conducted to evaluate the efficacy of desensitizing agent Propolis, after an in -office vital tooth bleaching and to compare its desensitizing effect to traditionally used desensitizing agent fluoride varnish.
- Trial name
- NCT05569590
- Testing
- Propolis, hydrogen peroxide 35%, fluoride varnish
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Pain, Postoperative
Regional Anesthesia for Head and Neck Reconstruction
By utilizing regional anesthesia blocks at the surgery tissue donor sites, it can potentially reduce post-operative pain while also reducing the use of opioids.
- Trial name
- NCT04304716
- Testing
- Regional Anesthesia
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Perioperative Inflammatory Response, Postoperative Pain
Suprazygomatic Maxillary Nerve Block Effect on Systemic Inflammatory Response in Cleft Palate Surgeries
the aim is to determine the value of adding bilateral supra zygomatic maxillary nerve block to general anesthesia in attenuating the systemic inflammatory response in paediatrics.
- Trial name
- NCT05495750
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Alaa Mohamed Abdel Salam Ibrahim Soliman
Pain, Postoperative
Effect of Preincisional Bupivakain Infiltration on Postoperative Narcotic Medication Requirement
Postoperative pain and use of narcotic analgesics after laparoscopic bariatric surgeries are problems that need to be solved in terms of patient comfort.
- Trial name
- NCT03071991
- Testing
- study group, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Anxiety, Pain, Postoperative
Postoperative Effects of Preoperative Anxiety
INTRODUCTION Patients who will have obesity surgery have about %48 psychiatric illnesses like anxiety disorder. Studies which analyze the relationship between preoperative anxiety level and postoperative pain had reported…
- Trial name
- NCT04432558
- Testing
- Spielberger's State-Trait Anxiety Inventory, Visual analog scale, Ramsay's sedation scale, Tramadol, paracetamol, diclofenac sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Baskent University
Postoperative Pain, Postoperative Edema
Patient Satisfaction and Recovery Outcomes Associated With Perioperative ELIXIR MD Use
The goal of this observational registry study is to characterize postoperative recovery outcomes in adult patients receiving standard-of-care perioperative light therapy using an FDA-cleared photobiomodulation device as part of…
- Conditions
- Postoperative Pain, Postoperative Edema, Postoperative Ecchymosis, Surgical Wound Healing
- Trial name
- NCT07311889
- Testing
- Perioperative photobiomodulation light therapy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Elixir MD Inc
Pain, Postoperative
Erector Spinae Plane Block vs Erector Spinae Plane Block With Serratus Anterior Plane Block in Thoracic Surgery
This pilot study will prospectively compare continuous Erector Spinae Plane block (ESP) versus combination of continuous Erector Spinae Plane block and single shot Serratus Anterior Plane block for post-operative pain management…
- Trial name
- NCT04349774
- Testing
- Control Group - ESP block with SAP block, Treatment Group - ESP block with SAP normal saline
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anna Uskova
Pain Postoperative
Foraminal Enlargement and Postoperative Pain.
The purpose of this study is to determine whether enlarging the apical foramen causes postoperative pain in teeth with necrotic pulp and apical periodontitis.
- Trial name
- NCT02770053
- Testing
- Foraminal enlargement
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Isparta Military Hospital
Knee Replacement, Postoperative Pain
Opioid-Sparing Protocol Comparing With Opioid-based Protocol After Bilateral Total Knee Arthroplasty
The concern for the opioid use in the total knee arthroplasty continues to rise in recent decades. Historically, the total knee arthroplasty consumed high doses opioids in the postoperative periods.
- Conditions
- Knee Replacement, Postoperative Pain, Opioid Use
- Trial name
- NCT04314505
- Testing
- Opioid-Sparing Protocol, Opioid-Based Patient Controlled Analgesia
- Where
- Taiwan
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Pain, Postoperative
Dexmedetomidine Reduce Postoperative Pain of C-section
The purpose of this study was to make sure whether the infiltration of dexmedetomidine around the uterus can reduce the pain of cesarean section surgery.Studies have shown that the use of local anesthetic infiltration around the…
- Trial name
- NCT05622656
- Testing
- Dexmedetomidine
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Apical Periodontitis
Effect of Passive Ultrasonic Irrigation Versus Needle Irrigation on Postoperative Pain and Periapical Healing
The aim of this study is to compare the effect of passive ultrasonic irrigation versus needle irrigation on post-operative pain and healing in patients with permanent posterior teeth with apical periodontitis treated in a single…
- Trial name
- NCT02913937
- Testing
- Passive ultrasonic irrigation, Endodontic needle
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain
Zynrelef vs Exparel: The Battle of Postoperative Pain Control After Robotic Sleeve Gastrectomy
The purpose of this study is to evaluate the use of an injectable combination of bupivacaine and meloxicam (Zynrelef) vs injectable liposomal bupivacaine (Exparel), two extended local anesthesia strategies currently approved by…
- Trial name
- NCT06349772
- Testing
- Zynrelef, Exparel
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Pain, Postoperative
Bupivacaine Hydrochloride for Pain Control in Cutaneous Surgery
The purpose of this study is to determine if the addition of bupivacaine HCl injections will improve pain control after skin surgery. This is a randomized clinical trial.
- Trial name
- NCT04260854
- Testing
- Bupivacaine Hydrochloride, Saline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Osteoarthritis, Pain
A SAD Study to Evaluate the Safety, Tolerability and PK/PD of iN1011-N17 in Healthy Volunteers
A First-in-Human, Double-blind, Randomized, Placebo-controlled, Single Ascending Dose Study to Evaluate Safety, Tolerability, Pharmacokinetics/Pharmacodynamics of iN1011-N17 after Oral Administration in Healthy Volunteers.
- Conditions
- Osteoarthritis, Pain, Post Herpetic Neuralgia, Neuropathic Pain
- Trial name
- NCT05496205
- Testing
- iN1011-N17
- Where
- Australia
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- iN Therapeutics Co., Ltd.
Caffeine, Pain, Joint
Pain Management After Shoulder Arthroplasty
Pain control is a critical after many surgical procedures. It is well known that orthopaedic surgeries are among the most painful procedures, with total joint arthroplasty being a clear example of this situation.
- Trial name
- NCT04872270
- Testing
- Total Shoulder Arthroplasty, Caffeine Pill, Percocet 10Mg-325Mg Tablet
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Total Abdominal Hysterectomy ,Pain , Acute Postoperative,Gabapentin , Celecoxib
Preoperative Analgesia in Non-gynecological Cancerous Women Who Underwent Elective Total Abdominal Hysterectomy
Comparison of effectiveness of preoperative Gabapentin with Celecoxib in reducing acute postoperative pain in abdominal hysterectomy, A randomized double blind controlled trial
- Trial name
- NCT03672162
- Testing
- Total abdominal hysterectomy
- Where
- Thailand
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Department of Medical Services Ministry of Public Health of Thailand
Neuromuscular Block, Residual, Pain
Methylprednisolone vs Dexamethasone: Effects on Sugammadex Reversal, Pain, and Nausea in Adults
This randomized controlled trial aims to compare the effects of intravenous methylprednisolone and dexamethasone on the reversal time of rocuronium by sugammadex in adult patients undergoing elective septoplasty or rhinoplasty.
- Conditions
- Neuromuscular Block, Residual, Pain, Postoperative Nausea
- Trial name
- NCT07187037
- Testing
- Methylprednisolone (MP), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Konya City Hospital
Postoperative Pain
Efficacy of Erector Spinae Plane Block in Caridac Surgery
Introduction: Opioid-based pharmacological treatment is frequently used in the treatment of pain after coronary artery bypass graft (CABG) surgery.
- Trial name
- NCT05312957
- Testing
- erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
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