Clinical trials: Pain, Postsurgical
Emergence Agitation, Postoperative Pain
Caudal Versus Intravenous Magnesium Sulfate on Emergence Agitation After Sevoflurane In Children.
Sevoflurane is the agent of choice for induction and maintenance of day care anesthesia in children and has a wide acceptance among pediatric anesthesiologists.
- Trial name
- NCT03846284
- Testing
- Bupivacaine, Magnesium sulfate 50mg, Magnesium sulfate 30 mg
- Where
- Egypt
- Volunteers
- 93 people
- Sponsor
- Mansoura University
Postoperative Pain
Intravenous Dexmedetomidin on Postoperative Pain After Hypospadias Repair in Children
This study aimed to evaluate the efficacy of intravenous ketorolac versus dexmedetomidine as analgesia after Hypospadias repair surgery to determine the optimal procedure for pain control and postoperative reduction of analgesic…
- Trial name
- NCT05194904
- Testing
- Dexmedetomidine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain, Postoperative
Outcomes Of Perioperative Pregabalin On Total Knee Arthroplasty
This study aims to provide high quality evidence from a double-blinded, randomized controlled trial on the efficacy of perioperative pregabalin in reducing morphine requirements, improving pain scores and reducing chronic…
- Trial name
- NCT02954484
- Testing
- pregabalin, Etoricoxib, paracetamol
- Volunteers
- 116 people
- Sponsor
- National University Hospital, Singapore
Postoperative Pain
The Effect of Serum Calcium Levels on Postoperative Pain: A Prospective Observational Study
This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk…
- Trial name
- NCT06957158
- Testing
- Peripheral venous blood, Arterial blood
- Where
- China
- Volunteers
- 350 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Intertransverse Process Block, Mtapa Block
Intertransverse Process Block Versus M-TAPA Block After Laparoscopic Hysterectomy
This randomized clinical trial aims to evaluate and compare the analgesicefficacy of the Intertransverse Process Block (ITPB) and the Modified Thoracoabdominal Nerve Block through Perichondrial Approach (M-TAPA) in patients…
- Conditions
- Intertransverse Process Block, Mtapa Block, Laparoscopic Hysterectomy, Postoperative Pain
- Trial name
- NCT07599787
- Testing
- Intertransverse Process Block, M-TAPA Block
- Volunteers
- 60 people
- Sponsor
- Antalya City Hospital
Thoracic Surgery
Comparison of Different Methods for Intra- and Postoperative Pain Therapy in Thoracic Surgery
The aim of the study is to determine which regional anaesthesiological technique (thoracic epidural analgesia or paravertebral block) is more suitable for thoracic surgery
- Trial name
- VERITAS (NCT05208619)
- Testing
- Regional anaesthesia
- Where
- 2 sites in Germany
- Volunteers
- 118 people
- Sponsor
- University Hospital, Bonn
Quality of Recovery After Mastectomy, Serratus Anterior Plane Block
Timing of Serratus Anterior Plane Block in Mastectomy Surgery
Postoperative pain following mastectomy may adversely affect early mobilization, patient comfort, and overall quality of recovery.
- Conditions
- Quality of Recovery After Mastectomy, Serratus Anterior Plane Block, Postoperative Pain, Mastectomy
- Trial name
- NCT07661212
- Testing
- Ultrasound-Guided Serratus Anterior Plane Block, Bupivacaine
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Postoperative Pain
Peripheral Nerve Block Anaesthesia for Ankle Fracture Surgery - an Exploratory Study: Is Rebound Pain a Problem?
The purpose of this exploratory study is to characterize the postoperative pain profile of patients undergoing operation with internal fixation of an ankle fracture under nerve block anaesthesia.
- Trial name
- NCT02100098
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Herlev Hospital
Lumbar Disc Herniation
QLB vs ESPB for Lumbar Spinal Surgery
Ultrasound-guided quadratus lumborum block (QLB) is a fascial plane block where local anesthetic is injected adjacent to the quadratus lumborum muscle to anesthetize the thoracolumbar nerves.
- Trial name
- NCT06477198
- Testing
- QLB, ESPB, Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Hypothermia, Postoperative Pain
Optimal Temperature Control in Body Contouring Procedures
The goal of this clinical trial is to compare different strategies for normothermia prevention in patients undergoing body contouring and other Aesthetic Plastic Surgery procedures.
- Conditions
- Hypothermia, Postoperative Pain, Postoperative Nausea, Postoperative Complications
- Trial name
- NCT06238739
- Testing
- Control - Standard Strategies for hypothermia prevention, Fluid warming before infusion and infiltration, Thermal convection blanket by water flow (Blanketrol)
- Where
- Colombia
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Pain, Postoperative
Intrathecal Paracetamol Before Spinal Anaesthesia With Chloroprocaine HCl 1% for Short Knee Procedures
This is a phase II, single centre, randomised, parallel-group, double-blind, three doses, placebo-controlled, exploratory efficacy and safety study.
- Trial name
- NCT03428230
- Testing
- 30 mg Paracetamol 3% (1 mL), 60 mg Paracetamol 3% (2 mL), 90 mg Paracetamol 3% (3 mL)
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- Sintetica SA
Nausea, Postoperative, Vomiting, Postoperative
Palonosetron vs. Ondansetron for Postoperative Nausea and Vomiting in Bariatric Surgery
Evaluate the safety and efficacy of palonosetron versus ondansetron to reduce and control post-operative nausea in bariatric surgery.
- Conditions
- Nausea, Postoperative, Vomiting, Postoperative, Patient Reported Outcomes, Pain, Postoperative
- Trial name
- NCT04533867
- Testing
- Laparoscopic sleeve gastrectomy, Palonosetron 1mcg/kg, Ondansetron 1 mg/kg, max dose 8 mg
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Bagcilar Training and Research Hospital
Pain, Postoperative
Erector Spinae Plane Block vs Quadro-Iliac Plane Block After Lumbar Instrumentation Surgery
Lumbar instrumentation surgery is associated with significant postoperative pain. This study compares the postoperative analgesic effectiveness of ultrasound-guided Erector Spinae Plane Block and Quadro-Iliac Plane Block in…
- Trial name
- NCT07354581
- Testing
- Erector Spinae Plane Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Bursa City Hospital
Post Operative Pain
Evaluation of Post-operative Pain During Retreatment in Different Visits
Endodontic retreatment is performed to alleviate symptoms of recurring infection, post-treatment disease after primary endodontic therapy. Retreatment can be performed in either single or multiple visits.
- Trial name
- NCT07014228
- Testing
- single visit re-endo, multi visit re-endo
- Where
- Pakistan
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Dentistry, Pakistan
Postoperative Pain Management, Postoperative Pain
Comparative Efficacy of Sciatic and Femoral Blocks in Ankle Surgery
Comparison of Anesthetic and Postoperative Analgesic Efficacy of Femoral and Popliteal Sciatic Block vs Femoral and Anterior Sciatic Block in Ankle Surgery
- Conditions
- Postoperative Pain Management, Postoperative Pain, Analgesia, Nerve Blocks
- Trial name
- NCT06758245
- Testing
- femoral and anterior sciatic nerve block, femoral and popliteal sciatic nerve block
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Anterior Cruciate Ligament Rupture, Pain, Postoperative
Effect of LIA on Postoperative Pain Following ACL Reconstruction
An anterior cruciate ligament (ACL) rupture is one of the most common sport injuries, which typically develops after a sudden knee torsion.
- Trial name
- NCT03873077
- Testing
- local infiltration analgesia
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Pelvic Organ Prolapse
Healing Statements and Their Effect on Post Operative Pain
This is a randomized clinical trial comparing the severity of post-operative pain and use of pain medication in women who are and are not exposed to healing statements before undergoing vaginal hysterectomy with minimally…
- Trial name
- PHSPOPC (NCT02502357)
- Testing
- Healing Statements
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Medstar Health Research Institute
Postoperative Pain, Pediatric ALL
Pediatric Pain Management - an Intervention Study
This study will explore nurses' pediatric postoperative pain management knowledge and clinical practices. The aim is to evaluate if a tailored educational intervention will improve nurses' knowledge and attitudes of pain…
- Trial name
- NCT03385681
- Testing
- Tailored Educational Intervention
- Where
- 6 sites in Norway
- Volunteers
- 876 people
- Sponsor
- Oslo University Hospital
Pain, Postoperative, Postoperative Nausea and Vomiting
Effect of Pulmonary Recruitment Maneuver (PRM) on Pain and Nausea After Laparoscopic Bariatric Surgery
The purpose of this prospective, blinded, randomized clinical trial is to investigate whether a ventilator-piloted PRM at the end of laparoscopic bariatric surgery could reduce overall postoperative pain and nausea.
- Trial name
- NCT03026530
- Testing
- Pulmonary recruitment maneuver, Laparoscopic bariatric surgery, Ventilator
- Volunteers
- 200 people
- Sponsor
- Region Östergötland