Clinical trials: Pain, Procedural, open to volunteers
Analgesia Assessment
Bupivacaine Liposome Suspension Administration to Decreasre Peri-procedural Pain in Interventional Radiology (IR) Procedures
This study evaluates the use of liposomal bupivacaine (Exparel), a long-acting local anesthetic, for peri-procedural pain control in patients undergoing interventional radiology (IR) procedures.
- Trial name
- NCT07535411
- Testing
- Liposomal Bupivacaine (EXPAREL®)/Bupivacaine
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anxiety, Pain
Investigating Pre-Procedural Anxiety and Effect of Analgesia on Intrauterine Device Placement and Endometrial Biopsy
The purpose of this study is to evaluate pre-procedural anxiety and patient pain perception with IUD insertion/ EMB procedure when using analgesia versus no analgesia by the end of the study and to evaluate the effect of age…
- Trial name
- NCT07031206
- Testing
- Paracervical block- Lidocaine without epinephrine, Benzocaine Gel applied to the cervix, Hydroxyzine Hydrochloride
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- The University of Texas Health Science Center, Houston
Watching a Comedy Video
Effect of Watching a Comedy Video on Anxiety, Pain, Procedural Readiness, and Uroflowmetric Parameters in Patients Undergoing Urodynamic Testing
This study aims to determine the effects of watching a comedy video on anxiety, pain, procedural readiness, and uroflowmetric parameters in patients undergoing urodynamic testing.
- Trial name
- NCT07728903
- Testing
- Watching a comedy video
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Procedural Pain in Newborns
Leg and Foot Massage for Pain in Newborns Receiving Heel Stick
This study aims to evaluate the effect of a leg and foot massage program on pain in newborns receiving heel stick for monitoring serum bilirubin levels.
- Trial name
- NCT07893028
- Testing
- Leg and Foot Massage
- Where
- Thailand
- Volunteers
- 42 people
- Sponsor
- Chulalongkorn University
Burn Injury, Procedural Anxiety
Effect of Short-Video Distraction During Burn Dressing on Anxiety, Pain, and Fear in Children
Burn dressing procedures can cause pain, anxiety, and fear in children. Distraction techniques may help children cope with these procedures and improve their comfort.
- Trial name
- BURN-VIDEO (NCT07906834)
- Testing
- Short-Video Distraction
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Samsun University
Procedural Pain, Pain Catastrophizing
Self-Adjusted Nitrous Oxide: A Feasibility Study in the Setting of Vasectomy
This study is being done to see if nitrous oxide during vasectomy decreases pain and anxiety, and also assess whether patients have better satisfaction when they control their own level of nitrous oxide during the procedure.
- Conditions
- Procedural Pain, Pain Catastrophizing, Procedural Anxiety
- Trial name
- SANO-VAS (NCT05895383)
- Testing
- Nitrous oxide
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Procedural Pain, Vaccination Pain
Cold Spray and Helfer Skin Tap for Pain During Infant Vaccination
This randomized controlled experimental study aims to evaluate the effects of cold spray and the Helfer Skin Tap technique on pain levels during intramuscular pneumococcal conjugate vaccine administration in 12-month-old infants.
- Conditions
- Procedural Pain, Vaccination Pain, Injection Pain
- Trial name
- NCT07779681
- Testing
- Cold spray, Helfer Skin Tap Technique
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hitit University
Acute Pain, Procedural Anxiety
VR for Steroid Joint Injections - Feasibility
The goal of the project is to implement virtual reality for pain and anxiety management for patients undergoing intra-articular glucocorticoid injections in the outpatient pediatric rheumatology clinic.
- Conditions
- Acute Pain, Procedural Anxiety, Juvenile Idiopahtic Arthritis
- Trial name
- NCT07778069
- Testing
- VR-PAT
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Nationwide Children's Hospital
Arthritis, Juvenile, Arthritis, Juvenile Idiopathic
Hypnotherapy for Needle-related Procedural Pain and Anxiety Management in a Pediatric Setting
The proposed study aims to evaluate the effectiveness of hypnotherapy as a non-pharmacological intervention for managing pain and anxiety during needle-related medical procedures in children aged 5 to 17 years.
- Conditions
- Arthritis, Juvenile, Arthritis, Juvenile Idiopathic, Lupus Erythematosus, Systemic, Dermatomyositis, Juvenile
- Trial name
- NCT07349667
- Testing
- Hypnotherapy
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Aarhus University Hospital
Procedural Pain
Intranasal Versus Intravenous Fentanyl For Procedural Analgesia in Preterm Neonates
Pain in neonatal life has profound long-term developmental impacts, so pain control is crucial. The intranasal (IN) route is a minimally invasive method for rapidly delivering fentanyl to provide short-term analgesia and sedation…
- Trial name
- NCT07190625
- Testing
- fentanyl intravenous, Fentanyl intranasal using atomizer, fentanyl intranasal direct
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Radiculopathy
Interest of the Virtual Reality as an Analgesic Support and in the Management the Pre-procedural Anxiety in Rheumatology
As a part of the current rheumatological practice skills, epidural injections through the sacrococcygeal hiatus take part in the strategy for managing radicular diseases.
- Trial name
- REAVIR (NCT05289999)
- Testing
- Virtual reality headset for first injection, Virtual reality headset for second injection
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Centre Hospitalier le Mans
Procedural Pain
To Explore the Optimal Dose of Dexmedetomidine for Skull Pin Fixation in Intracranial Surgery
Skull pin fixation is commonly used in intracranial surgery, which can increase the surgical field of view. Because skull pin fixation is a very irritating and painful medical treatment, it often results in tachycardia (>150-160…
- Trial name
- NCT06837818
- Testing
- Dexmedetomidine
- Volunteers
- 40 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Anxiety, Pain
A Study of the Impact of a Virtual Reality Medical Device (HypnoVR® Headset) on Anxiety and Pain in Interventional Radiology.
Patients undergoing interventional radiology procedures frequently experience significant anxiety and procedural pain despite standard care.
- Conditions
- Anxiety, Pain, Radiology, Interventional
- Trial name
- HYPNO-VR (NCT07668050)
- Testing
- Immersive Virtual Reality
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Clermont-Ferrand
Critical Illness, Pain
Soap-and-Water Bed Bath Versus Disposable Wipe Bath in the Same ICU Patients
Bed bathing is a routine nursing procedure in the intensive care unit (ICU). In the study units, every patient routinely receives both a traditional bed bath with warm water and soap (every 10 days) and a bath with pre-packaged…
- Conditions
- Critical Illness, Pain, Procedural Anxiety
- Trial name
- YBU-BANYO (NCT07919912)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Sinop Atatürk State Hospital
Burns, Acute Pain
VR-PAT During Home Burn Dressings - Multisite
This study will evaluate the effectiveness of smartphone Virtual Reality Pain Alleviation Therapy (VR-PAT) as a pain distraction tool during repeated at-home burn dressing changes among 100 children (age 6-17 years) with a burn…
- Conditions
- Burns, Acute Pain, Procedural Pain, Injuries
- Trial name
- NCT05673551
- Testing
- VR-PAT
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Nationwide Children's Hospital
Burns, Pain, Procedural
Virtual Reality for Pain and Fear in Children With Burns
Burn injuries are very painful for children, especially during dressing changes when the wound is cleaned and re-bandaged. This procedure, while necessary, can cause pain, fear, and distress that may make children afraid of…
- Conditions
- Burns, Pain, Procedural, Pain, Acute, Fear
- Trial name
- VR-PFB (NCT07740980)
- Testing
- Virtual Reality (VR) Distraction, Standard Burn Dressing Care
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Children, Adolescent
How Digital Media Affects Kids' Healthcare Experiences and Outcomes
The goal of this clinical trial is to learn whether different forms of media (2D, 360, or 360 in virtual reality) have different impacts on pre-procedural anxiety and post-procedural pain in children.
- Conditions
- Children, Adolescent, Anxiety, Pain
- Trial name
- NCT07073027
- Testing
- 2D video on smartphone, 360 video on smartphone, 360 video on smartphone inserted into VR cardboard headset
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- British Columbia Children's Hospital
Procedural Pain
Comparison of Virtual Reality, EMLA Cream, and Standard Care for Pain During Blood Draws in Children
This randomized controlled trial evaluates methods to reduce pain during venipuncture in children aged 3 to 15 years. The study compares three approaches: virtual reality distraction using a VR headset, topical anesthesia with…
- Trial name
- NCT07763132
- Testing
- Virtual Reality Distraction, Lidocaine-Prilocaine Cream
- Where
- Czechia
- Volunteers
- 450 people
- Sponsor
- Marie Lulková
Total Knee Arthroplasty, Total Knee Arthroplasty Recovery
Effects of Stress Ball Use and Breathing Exercises on Pain and Vital Signs During Drain Removal After Total Knee Arthroplasty
This randomized controlled trial aims to evaluate the effects of stress ball use and breathing exercises on procedural pain and vital signs during drain removal in patients undergoing total knee arthroplasty.
- Conditions
- Total Knee Arthroplasty, Total Knee Arthroplasty Recovery, Pain After Knee Arthroscop
- Trial name
- TDP (NCT07586436)
- Testing
- 3. Control Group Description, 1. Stress Ball Intervention Description, 2. Breathing Exercise Intervention Description
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Prostate Cancer (Diagnosis), Prostate Biopsy
TENS During Transperineal Prostate Biopsy
Transperineal prostate biopsy is a safe and effective method of diagnosing prostate cancer. When performed under local anaesthesia in an outpatient setting, it can cause significant pain, particularly during the periprostatic…
- Conditions
- Prostate Cancer (Diagnosis), Prostate Biopsy, Pain, Procedural
- Trial name
- TENS 2 (NCT07578324)
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS)
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Gdansk