Clinical trials: Pain, Radiating
Low Back Pain, Nerve Entrapment Syndrome
The Frequency of Superior Cluneal Nerve Entrapment Diagnosed With Ultrasound Guided Nerve Block
Cluneal nerves are a group of pure sensory nerves that provide direct cutaneous innervation to the buttocks. Superior cluneal nerve(SCN) originates from the T11-L5 nerve roots and has at least 3 branches from medial to lateral…
- Conditions
- Low Back Pain, Nerve Entrapment Syndrome, Radiating Pain
- Trial name
- NCT05303597
- Testing
- ultrasound-guided diagnostic nerve block with lidocaine
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Istanbul University - Cerrahpasa
Intervertebral Disc Displacement, Sciatica
The Effectiveness of Doin (Conduction Exercise) of the Pelvic Joint for HLD With Radiating Leg Pain
A prospective pilot study will be conducted to investigate the effectiveness and safety in herniated lumbar disc (HLD) patients receiving integrative Korean medicine treatment including Doin (conduction exercise) at a Korean…
- Conditions
- Intervertebral Disc Displacement, Sciatica, Sciatic Radiculopathy
- Trial name
- NCT03571503
- Testing
- Doin (conduction exercise), Herbal medicine, Chuna manual therapy
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Jaseng Medical Foundation
Pain, Radiating
Surgery Prevention by Transforaminal Injection of Epidural Steroids for Cervical Radicular Pain
Cervical radicular pain is a common cause of disability and pain in the upper extremity and neck with an annual incidence of 83.2/100,000 (1).
- Trial name
- SPIES (NCT02226159)
- Testing
- Lidocaine, Lidocaine with Dexamethasone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- OrthoCarolina Research Institute, Inc.
Sub Acute Low Back Pain With Radiating Symptoms
Algo K Specific Manual Therapy for Sub Acute Low Back Pain With Radicular Symptoms
This study evaluates the effectiveness of a specific manual therapy approach based on the Algo-K decision algorithm in patients with subacute low back pain radiating to the lower limb.
- Trial name
- ALGO-K (NCT07118033)
- Testing
- Specific Manual Therapy, Non specific Manual Therapy
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Pain, Pain, Radiating
Neck-specific Training or Prescribed Physical Activity for Patients With Cervical Radiculopathy
The overall objective is to evaluate if treatment with a neck-specific exercise program and cognitive behavioural approach improves the outcome compared with prescribed, self-mediated and progressive physical activity in patients…
- Trial name
- NCT01831271
- Testing
- Prescribed physical activity, Neck specific training
- Where
- Sweden
- Volunteers
- 144 people
- Sponsor
- Karolinska University Hospital
Low Back Pain, Radiating Pain
Effect of Nitrous Oxide in Treating Neuropathic Pain: A Study in Chronic Low Back Pain Patients
Epidural injection will be completed under fluoroscopy and all patients will receive 1-4 mg of Midazolam for relaxation before procedure and, if needed, 50-100 mcg of Fentanyl intravenous (IV).
- Trial name
- NCT01172600
- Testing
- Entonox, Oxygen
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- The Cleveland Clinic
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Pain, Chronic, Pain, Radiating
Change in Pain and Quality of Life Following SCS for Chronic Pain
Study Title Subject-reported treatment efficacy and procedure satisfaction (steps) study.BURST study- a prospective observational clinical study examining the changes in quality of life and pain following spinal cord stimulation…
- Conditions
- Pain, Chronic, Pain, Radiating, Pain, Back, Pain Syndrome
- Trial name
- BURST (NCT03421951)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- KM Clinical Research Group
Radiating Pain, Myelopathy
Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
This study randomizes neck and arm pain patients being treated with discectomy and anterior interbody fusion into two groups: one to receive a new ceramic implant and a control group with a more traditional plastic implant.
- Conditions
- Radiating Pain, Myelopathy, Cervicobrachial Syndrome
- Trial name
- CASCADE (NCT01511445)
- Testing
- Anterior cervical discectomy and fusion (ACDF) with PEEK Cage, Anterior cervical discectomy and fusion (ACDF) with a Valeo CSC Cage
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Amedica Corporation
Radiating Pain in the Upper Extremity
The Efficacy and Safety of Early MSAT on Radiating Pain in the Upper Extremity
This study is a open-label, randomized controlled trail. condition/disease: radiating pain in the upper extremity. treatment/intervention: motion style acupuncture treatment
- Trial name
- NCT06086899
- Testing
- Cervical motion style acupuncture treatment(Trapezius, Rhomboid, Scalene), Korean medical treatment
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Radiculopathy
Mckenzie Technique vs Conventional Therapy in Correcting Lateral Shift in Chronic Lumber Radiculapthy Patient
Radiculopathy or nerve root pain arises from disc herniation, spinal stenosis/post-operative scarring, radiating down the leg in a dermatomal pattern.
- Trial name
- NCT07080047
- Testing
- Mackenzie exercise for lateral shift, Traditional physical therapy
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Oral Mucositis, Quality of Life
Retrospective Observational Study of Oral Complications and Quality of Life in Head and Neck Cancer Patients Treated With Radiotherapy or Chemoradiotherapy.
Head and Neck cancer patients receiving radiation therapy (with or without chemotherapy) suffer several oral complications, such as oral mucositis, which impairs quality of life of patients during radiotherapy and in the…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- NCT07739771
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Mucosa Innovations, S.L.
Radiating Leg Pain, Disc Protrusion
A Randomized, Controlled Trial of Treatment for Disc Herniation With Radiating Leg Pain
Hypothesis - This study is designed to evaluate the results of using the Orthotrac Pneumatic Vest versus an EZ form brace in patients with radiating leg pain from disc bulge / protrusion / herniation.
- Trial name
- NCT00220935
- Testing
- Orthotrac Pneumatic Vest
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Texas Back Institute
Pain, Neck, Cervical Radiculopathy
Are Stabilization Exercises Effective After Epidural Steroid Injection in Patients With Cervical Radiculopathy?
Cervical radiculopathy was first described in 1943 by researchers named Semmes and Murphy, years later than lumbosacral radiculopathy.
- Conditions
- Pain, Neck, Cervical Radiculopathy, Pain, Radiating
- Trial name
- NCT05307211
- Testing
- Cervical Interlaminar Epidural Steroid Injection, Neck Stabilization Exercises, Neck and Scapular Stabilization Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Marmara University
Pain, Burning, Pain, Crushing
A Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Cancer-related Pain
The purpose of this study is to compare the safety and effectiveness of JNJ-42160443 with placebo in the treatment of chronic, moderate to severe cancer-related pain in terminally ill patients with a diagnosis of active cancer.
- Conditions
- Pain, Burning, Pain, Crushing, Pain, Migratory, Pain, Radiating
- Trial name
- NCT00929188
- Testing
- JNJ-42160443
- Where
- 40 sites in United States, France and 3 more
- Volunteers
- 100 people
- Sponsor
- Janssen Research & Development, LLC
Cervical Pain, Neuropathic Pain
PROs in Chronic Cervical Pain Patients With Accompanying Upper Limb Radiating Pain Treated With Pregabalin
The purpose of this study is to evaluate the effect of pregabalin on patient reported outcomes compared with conventional analgesic care in chronic cervical pain patients with accompanying upper limb radiating pain (neuropathic…
- Conditions
- Cervical Pain, Neuropathic Pain, Radiating Pain
- Trial name
- NCT02868359
- Testing
- No Intervention
- Where
- 33 sites in Japan
- Volunteers
- 369 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Carpal Tunnel Syndrome, Central Sensitisation
Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome
This study aims to compare central sensitization parameters between carpal tunnel syndrome (CTS) patients with extra median symptom distribution and those with typical, median nerve-related symptoms.
- Conditions
- Carpal Tunnel Syndrome, Central Sensitisation, Pain, Radiating
- Trial name
- NCT07114913
- Testing
- Nerve ultrasound, Nerve conduction studies, Pressure pain threshold
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Oral Mucositis, Quality of Life
Effect of a Novel Topical Composition on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.
The use of a novel topical mucosa composition (XCM-OM118) comprising 2-(trimethylazaniumyl) acetate; (2R,3R,4S)-pentane-1,2,3,4,5-pentol; Hexadecanoic acid; (9Z, 12Z)-octadeca-9,12-dienoic acid; octadecanoic acid…
- Conditions
- Oral Mucositis, Quality of Life, Mucositis, Pain
- Trial name
- STOPOMP (NCT05635929)
- Testing
- XCM-OM118 Composition comprising olive oil, betaine and xylitol
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Mucosa Innovations, S.L.
Pain, Chronic, Pain, Back
Ultra-high Frequency (500 KHz) Spinal Cord Stimulation for Treatment of Chronic Back Pain or Lower Limb Pain
This study is a prospective, single-arm, open label, single center to confirm the effectiveness and safety of an ultra-high frequency (500 KHz) spinal cord stimulation in patients with chronic back pain or lower limb pain.
- Conditions
- Pain, Chronic, Pain, Back, Pain, Radiating
- Trial name
- NCT03543085
- Testing
- GiMer Medical MN 1000 External Stimulator
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- GiMer Medical
Low Back Pain, Leg Pain and/or Back Pain
Sciatic Neural Mobilization in Lumbar-Related Leg Pain
Low back pain is one of the most prevalent musculoskeletal disorders worldwide and significantly reduces individuals' quality of life, functional capacity, and productivity.
- Trial name
- NCT07588919
- Testing
- Sciatic neural mobilization
- Volunteers
- 52 people
- Sponsor
- Istinye University