Clinical trials: Pain, completed
Post Operative Pain
Quadratus Luborum Block Using Bupivacaine Versus Bupivacaine-Dexamethasone in Laparoscopic Cholecystectomy
The aim of the present study was to compare the effectiveness of transmuscular Quadratus Lumborum block using Bupivacaine versus Bupivacaine- Dexamethasone in providing analgesia in patients undergoing laparoscopic…
- Trial name
- NCT03956966
- Testing
- TQL block with saline, TQL block with Bupivacaine, TQL block with Bupivacaine and dexamethasone
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Minia University
Arthroscopic Shoulder Surgery
Pain Management in Arthtroscopic Shoulder Surgery
It is compared that combined suprascapular and infraclavicular nerve blocks to interscalene nerve block for clinical outcomes after shoulder surgery
- Trial name
- PMSS (NCT04101266)
- Testing
- Interscalene block, suprascapular and infraclavicular nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Pain
Neural Correlates of Acute Pain Dynamics
This work aims to study the neural correlates and determinants of pain dynamics related to changes in a noxious stimulus.
- Trial name
- NCT05669924
- Testing
- Methylphenidate
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Chronic Pain
Chronic Pain Self-management Support With Pain Education and Exercise
The purpose of this study is to determine whether the combination of self-management support, pain science education, and individualized, goal-oriented exercises helps people with chronic pain to increase their function.
- Trial name
- COMMENCE (NCT02422459)
- Testing
- COMMENCE
- Where
- Canada
- Volunteers
- 102 people
- Sponsor
- McMaster University
Pain, Neuropathic Pain
Radicle Relief 2: A Study of Health and Wellness Products on Pain and Health Outcomes
A randomized, blinded, placebo-controlled study assessing the impact of health and wellness products on pain and other health outcomes
- Conditions
- Pain, Neuropathic Pain, Nociceptive Pain
- Trial name
- NCT05837923
- Testing
- Relief Active Study Product 1.1 Usage, Relief Active Study Product 1.2 Usage, Relief Active Study Product 2.1 Usage
- Where
- United States
- Volunteers
- 2,016 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Postoperative Pain
Pediatric Tonsillectomy Pain Reduction Study
Tonsillectomy is associated with a significant decrease quality of life in children secondary to pain, which is worsened with swallowing.
- Trial name
- NCT00678379
- Testing
- lidocaine (1%) + bupivacaine (0.5%), Normal saline, Lidocaine (1%) + Bupivacaine (0.5%) + Clonidine (25mcg)
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Vanderbilt University Medical Center
Hypogonadism, Opioid-Related Disorders
Clomiphene Citrate for the Treatment of Low Testosterone Associated With Chronic Opioid Pain Medication Administration
The purpose of this randomized controlled clinical trial is to evaluate the effects of clomiphene citrate compared to placebo (substance without active medication) in men who are taking pain medication (opioids) for chronic pain…
- Conditions
- Hypogonadism, Opioid-Related Disorders, Male Infertility
- Trial name
- NCT01880086
- Testing
- Clomiphene citrate
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Weill Medical College of Cornell University
Pain
Sucrose Practices for Pain in Neonates
Recent studies show that babies in hospital undergo an average of 4 to 5 painful procedures, such as heel lances, every day. Sucrose (sugar water) has been shown to be effective for reducing pain during invasive procedures and is…
- Trial name
- SPiN (NCT02134873)
- Testing
- sucrose
- Where
- Canada
- Volunteers
- 291 people
- Sponsor
- The Hospital for Sick Children
Children, Adult
Pilates Exercises on Pain, Functional Disability and ROM Among Children With Text Neck Syndrome
Text Neck' is a term used to describe a posture that is caused by leaning forward for long period of time such as reading or texting on smartphone.
- Trial name
- NCT06893705
- Testing
- Conventional Therapy, Pilates+Conventional Therapy
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Rheumatoid Arthritis
Progressive Resistance Exercise in Rheumatoid Arthritis
A randomized controlled trial with rheumatoid arthritis patients will be realized. Patients will be randomized into two groups. Experimental group will do a 12 weeks training of progressive resistance exercise for global muscles…
- Trial name
- NCT02219022
- Testing
- Control group, Experimental group
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Federal University of São Paulo
Lumbar Disc Herniation
Clinical Research on the Efficacy of Thread-embedding Acupuncture on Herniated Intervertebral Disc of Lumbar Spine
This clinical trial is designed to evaluate the efficacy and safety of thread-embedding acupuncture for treatment of lumbar herniated intervertebral disc (L-HIVD) by assessing pain, function, and quality of life.
- Trial name
- NCT03236753
- Testing
- Thread-embedding Acupuncture (TEA)
- Where
- 4 sites in South Korea
- Volunteers
- 70 people
- Sponsor
- Kyunghee University Medical Center
Knee Arthritis Osteoarthritis, Chronic Knee Pain
The Predictive Value of Ultrasonographic Quadriceps Muscle Parameters for Genicular Nerve Block Outcomes in Knee Osteoarthritis
The goal of this observational study is to learn whether thigh muscle structure can help predict pain relief after a genicular nerve block in people with knee osteoarthritis.
- Trial name
- NCT07781059
- Testing
- genicular nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 41 people
- Sponsor
- Marmara University
Cervical Radiculopathy
Conservative Therapy Versus Epidural Steroids for Cervical Radiculopathy
The main objective of this study is to determine whether interventional treatment (i.e. epidural steroids), conservative therapy, or the combination, is superior for cervical radiculopathy.
- Trial name
- NCT01144923
- Testing
- Gabapentin and/or Nortriptyline, Physical therapy, Epidural Steroid Injections (ESI), Combination treatment
- Where
- 2 sites in United States
- Volunteers
- 169 people
- Sponsor
- Johns Hopkins University
Osteoarthritis, Knee
Residual Pain After Successful Implant of Metaphyseal Sleeves in Total Knee Arthroplasty
: Total knee revision arthroplasty is increasing in daily practice and will become more relevant in the years to come. Bone loss is a significant challenge in total knee arthroplasty (TKA) especially in revision procedures.
- Trial name
- NCT04995679
- Testing
- Implant of metaphyseal sleeves in Total knee arthroplasty
- Where
- Italy
- Volunteers
- 85 people
- Sponsor
- University of Milan
Cervical Pain, Postural Balance
Balance Performance in Dual Task in Patients With Cervical Disc Herniation Related Chronic Neck Pain:a Comparative Study
Intense pain and moderate disability are seen most patients with symptomatic cervical disc herniation (CDH). Since neck motion and motor control are associated with changes in neck pain and disability, it is highly likely that…
- Trial name
- NCT05338788
- Testing
- neck pain and dual task
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Child Behavior
The Effect of Distraction Technique on Children's Pain, Anxiety and Fear of Medical Procedure in Invasive Interventions
This study was conducted on the effects of visual and/or auditory distraction techniques applied to children aged 7-12 years who applied to Çanakkale Mehmet Akif Ersoy State Hospital Gynecology and Pediatric Emergency Service…
- Trial name
- NCT05533827
- Testing
- Kaleidoscope, Music, Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 144 people
- Sponsor
- Bandırma Onyedi Eylül University
Osteoarthritis, Knee, Knee Osteoarthritis
AP-003-C Study to Confirm the Efficacy of Ampion™ in Adults With Pain Due to Severe Osteoarthritis of the Knee
This is a phase 3 randomized study to confirm the efficacy of an intra-articular injection of Ampion™ in adults with pain due to severe osteoarthritis of the knee.
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Knee Arthritis, Knee Pain Chronic
- Trial name
- NCT03182686
- Testing
- 4 mL injection of Ampion
- Where
- 13 sites in United States
- Volunteers
- 168 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Acute Toothache Patients Above Moderate Pain After Teeth Extraction Surgery
Phase 3 Study of Tramadol Hydrochloride/Acetaminophen SR Tab. & Tramadol Hydrochloride/Acetaminophen Tab. in Acute Toothache Patients After Teeth Extraction Surgery
A randomized, double-blind, active-controlled, parallel, multicenter Phase 3 study of Tramadol hydrochloride/Acetaminophen SR Tab. \& Tramadol hydrochloride/Acetaminophen Tab.
- Trial name
- NCT01920386
- Testing
- Tramadol hydrochloride/Acetaminophen Tab., Tramadol hydrochloride/Acetaminophen SR Tab.
- Volunteers
- 240 people
- Sponsor
- Daewon Pharmaceutical Co., Ltd.
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Neuralgia, Pudendal Nerve
Comparison of Ultrasound-guided Transgluteal and Finger-guided Transvaginal Pudendal Nerve Block Techniques
Pudendal neuralgia (PN) is a painful and disabling condition, which reduces the quality of life as well. Pudendal nerve injections are essential for the diagnosis and the management of PN.
- Conditions
- Neuralgia, Pudendal Nerve, Pudendal Nerve Block
- Trial name
- NCT03973983
- Testing
- Ultrasound-guided transgluteal pudendal nerve injection (TG-PNI), Finger-guided transvaginal pudendal nerve injection (TV-PNI)
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Derince Training and Research Hospital
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