Clinical trials: Pain, completed
Reduced Corneal Sensation
Effect of Superficial Keratotomy on Reducing Postoperative Pain Fallowing Conjuctival Flap
During conjunctival flap surgery the corneal epithelium is removed and a conjunctival flap is placed on the cornea and after a few weeks the conjunctiva covers the surface of the eye.
- Trial name
- NCT05494931
- Testing
- corneal neurotomy
- Where
- Iran
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Iran University of Medical Sciences
Pain
Safety, Tolerability, Analgesic Effect, and Feasibility of Intranasal CT001 in Pediatric Patients
The proposed study aims to investigate the safety, tolerability, analgesic efficacy, and feasibility of intranasal sufentanil/ketamine (CT001) in pediatric participants attending an acute care (i.e. emergency) setting.
- Trial name
- NCT06364072
- Testing
- CT001
- Where
- 7 sites in Spain, United Kingdom
- Volunteers
- 155 people
- Sponsor
- Cessatech A/S
Compartment Syndrome of Leg
Chronic Exertional Compartment Syndrome (CECS) Treated With Abobotulinumtoxin A
Chronic Exertional Compartment Syndrome (CECS) is a painful condition affecting runners and it is caused by a reversible increase in pressure within a closed compartment in the leg.
- Trial name
- CECS (NCT05466539)
- Testing
- AbobotulinumtoxinA
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Emory University
Interstitial Cystitis, Painful Bladder Syndrome
Physiotherapeutic Interventions Applied to the Bladder Pain Syndrome
Related to urological and gynecological systems, patients with Bladdeer Pain Syndrome (BPS) often present pain, pressure and chronic discomfort in suprapubic and perineal area associated with low urinary tract symptoms.
- Conditions
- Interstitial Cystitis, Painful Bladder Syndrome, Bladder Pain Syndrome
- Trial name
- NCT03755375
- Testing
- TENS, Postural exercises, Biofeedback
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo General Hospital
Telenursing
Telephone Counseling in the Education of the Patient With Gastritis
It is planned to investigate the effect of telephone counseling on pain and sleep quality in patients with gastritis who have received gastritis management training.
- Trial name
- NCT04669275
- Testing
- Telephone Counselıng
- Where
- Turkey (Türkiye)
- Volunteers
- 112 people
- Sponsor
- Eskisehir Osmangazi University
Pain, Postoperative
The PENG Block in Elective Hip Surgery and Its Effect on Postoperative Pain and Length of Stay.
Effective postoperative pain management in elective hip surgery is crucial for the patients well-being, rapid mobilisation and potential reduction of length of stay.
- Trial name
- NCT05056675
- Testing
- PENG block
- Where
- Switzerland
- Volunteers
- 151 people
- Sponsor
- Hôpital Fribourgeois
Pain, Postoperative, Anxiety
Effect of VR on Anxiety and Pain in Gynecological Surgery
Rationale: Lack of postoperative acute pain management is associated with increased morbidity, longer recovery time, more opioid use and subsequently increased health care costs.
- Conditions
- Pain, Postoperative, Anxiety, Pain Catastrophizing, State Anxiety
- Trial name
- VRAP-G (NCT04687501)
- Testing
- Virtual Reality
- Where
- Netherlands
- Volunteers
- 60 people
- Sponsor
- Zuyderland Medisch Centrum
Chronic Shoulder Pain
Comparison of the Effectiveness of 5% and 10% Dextrose Treatments in Patients With Chronic Shoulder Pain: Ultrasound-Guided Perineural Injection
Chronic shoulder pain is a condition that typically lasts longer than three months and affects daily life. Among musculoskeletal system pathologies, shoulder pain ranks third after spine and knee pathologies.
- Trial name
- NCT07428512
- Testing
- dextrose
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara City Hospital Bilkent
Uterine Fibroids, Polyps
HOME Study: Hysteroscopic Office Myomectomy Evaluation
The purpose of this study is to demonstrate safety and effectiveness of the MyoSure Tissue Removal System when used by community gynecologists in an office setting for the treatment of patients with symptomatic intrauterine…
- Trial name
- HOME (NCT01152112)
- Testing
- Myomectomy
- Where
- 9 sites in United States
- Volunteers
- 74 people
- Sponsor
- Hologic, Inc.
Back Pain, Pain
Evaluation of Clinical Outcomes of Pulse Widths in Spinal Cord Stimulation
The purpose of this study is to evaluate the effect of pulse widths <500 μsec and >1000 μsec on clinical outcomes during a temporary SCS trial.
- Trial name
- NCT03756012
- Testing
- Algovita Spinal Cord Stimulation System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Kettering Health Network
Back Pain Lower Back Chronic
A Study of Duloxetine (LY248686) in Participants With Chronic Low Back Pain
The purpose of the study is to assess the efficacy and safety of duloxetine in participants with Chronic Low Back Pain (CLBP).
- Trial name
- NCT01855919
- Testing
- Duloxetine
- Where
- Japan
- Volunteers
- 458 people
- Sponsor
- Eli Lilly and Company
Postoperative Pain
Adductor Canal Block With Continuous Infusion Versus Intermittent Boluses and Morphine Consumption
The investigators believe sufficient spread to all nerves within the adductor canal-and thereby sufficient analgesia-can only be obtained by bolus injections and not by continuous infusions via a catheter.
- Trial name
- NCT02539628
- Testing
- ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Pia Jaeger
Plantar Fasciitis, Chronic, Calcaneal Spur
Inferior Calcaneal Nerve Radiofrequency Ablation for Chronic Heel Pain
This prospective single-arm pilot interventional study aims to evaluate the effectiveness of ultrasound-guided radiofrequency ablation of the inferior calcaneal nerve in patients with chronic heel pain refractory to conservative…
- Conditions
- Plantar Fasciitis, Chronic, Calcaneal Spur, Chronic Heel Pain
- Trial name
- ICN-RF (NCT07537907)
- Testing
- Ultrasound-Guided Radiofrequency Ablation of the Inferior Calcaneal (Baxter) Nerve
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Şahide Eda Artuç
Dermatologic Complications, Pain
Scrambler Therapy in Treating Chronic Pain in Patients With Rash From Varicella Zoster Virus Infection
This pilot clinical trial studies how well scrambler therapy works treating chronic pain in patients with rash from varicella zoster virus infection.
- Conditions
- Dermatologic Complications, Pain, Viral Infection
- Trial name
- NCT01347736
- Testing
- scrambler therapy, questionnaire administration, dermatologic complications management/prevention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Tracheal Intubation Morbidity, Pain
Prediction of Hemodynamic Response to Intubation by ANI Variation During Standardized Stimulation
The objective : to investigate a correlation between ANI following a standardized nociceptive stimulus and hemodynamic or somatic reactions during orotracheal intubation. Piloted study.
- Trial name
- ANI_LARYNGO (NCT04354311)
- Testing
- ANI
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Lille
Brain Concussion
LED Therapy for the Treatment of Concussive Brain Injury
A double blind randomized trial of light-emitting diode (LED) therapy for patients suffering from mild traumatic brain injury (mTBI).
- Trial name
- NCT02383472
- Testing
- MedX Health Console model 1100
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Ambulatory Hand Surgery
Patient Education and Use of Post Operative Pain Medication in Ambulatory Hand Surgery: a Randomized Controlled Trial
There is a current opioid epidemic in the United States partially fueled by excess prescribing practices after surgery. The objective of this study is to decrease the amount of opioids needed after ambulatory hand surgery.
- Trial name
- NCT03219177
- Testing
- Patient education regarding indications for opioid use and side effects of opioid use after hand surgery, Standard of care post-operative counseling
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Postoperative Pain Management, Open-heart Surgery
Erector Spinae Plane Block and Postoperative Recovery After Open-Heart Surgery
This prospective randomized controlled clinical trial evaluated the effects of bilateral erector spinae plane block (ESPB) on postoperative systemic functions in adult patients undergoing elective open-heart surgery via median…
- Conditions
- Postoperative Pain Management, Open-heart Surgery, Median Sternotomy, Erector Spinae Plane Block
- Trial name
- ESPB-SYSHEART (NCT07259057)
- Testing
- Erector spinae plane block (ESPB), Intravenous Opioid Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Low Back Pain
Active Break Intervention on Low Back Pain and Musculoskeletal Discomfort During Prolonged Sitting Among Young People
The most recent evidence showed that the COVID-19 (coronavirus disease 2019, National Institutes of Health) pandemic caused an increase in low back pain (LBP) prevalence and intensity among young people.
- Trial name
- NCT05810519
- Testing
- Active break with the proposed lumbar and hip extension exercises, Self-care recommendations
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Józef Piłsudski University of Physical Education
Post Endodontic Pain
Comparative Evaluation of Transdermal and Oral Drugs for Management of Post-Endodontic Pain
This clinical trial evaluated whether two drugs delivered through transdermal drug delivery systems reduced post-endodontic pain as effectively as two orally administered medications in adult patients undergoing root canal…
- Trial name
- PATCH-PAIN (NCT07610265)
- Testing
- Ketoprofen transdermal patch, Fentanyl transdermal patch, Diclofenac sodium tablet
- Where
- India
- Volunteers
- 80 people
- Sponsor
- Nims University Rajasthan
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