Clinical trials: Pain, completed
Degenerative Disc Disease
Safety and Preliminary Efficacy Study of Mesenchymal Precursor Cells (MPCs) in Subjects With Lumbar Back Pain
The purpose of this study is to compare two doses of immunoselected, culture-expanded, nucleated, allogeneic adult MPCs when combined with hyaluronic acid to two control intradiscal injections in subjects with chronic low back…
- Trial name
- NCT01290367
- Testing
- Single Dose MPCs Injection, Single injection of saline solution, Single injection of hyaluronic acid
- Where
- 14 sites in United States, Australia
- Volunteers
- 100 people
- Sponsor
- Mesoblast, Ltd.
Breast Cancer, Pain, Postoperative
Comparative Sensory Mapping of Regional Anesthesia Techniques in Breast Cancer Surgery
Various regional anesthesia techniques, either individually or in combination, can be utilized for analgesia in breast cancer surgery.
- Trial name
- NCT06911892
- Testing
- Group Serratus Anterior Plane Block, Group Parasternal Block, Group Interpectoral+Pectoserratus Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Samsun University
Postoperative Pain
Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia
Morphine is usually used for pain relief after cesarean delivery. However, sometimes it is not available, the patient might be allergic to morphine or intolerant to its side effects.
- Trial name
- NCT03592992
- Testing
- Spinal Hydromorphone, Spinal Morphine
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Dermatologic Complications, Pain
Scrambler Therapy in Treating Chronic Pain in Patients With Rash From Varicella Zoster Virus Infection
This pilot clinical trial studies how well scrambler therapy works treating chronic pain in patients with rash from varicella zoster virus infection.
- Conditions
- Dermatologic Complications, Pain, Viral Infection
- Trial name
- NCT01347736
- Testing
- scrambler therapy, questionnaire administration, dermatologic complications management/prevention
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Mayo Clinic
Pain
Diclofenac Potassium Alone Versus Diclofenac Potassium With Hyoscine-N-butyl Bromide (HBB in Endoscopy
Diclofenac is a proven, commonly prescribed nonsteroidal anti-inflammatory drug (NSAID) that has analgesic, anti-inflammatory, and antipyretic properties, and has been shown to be effective in treating a variety of acute and…
- Trial name
- NCT04125771
- Testing
- Diclofenac + HBB with hysteroscopy
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Primary Dysmenorrhea
The Effect of Connective Tissue Manipulation on General Health and Emotional Status in Women With Primary Dysmenorrhea
The purpose of this study was to reveal the effects of connective tissue manipulation (CTM) on pain severity, fatigue, sleep quality, general health status, systemic symptoms, anxiety and depression in women with primary…
- Trial name
- NCT04509934
- Testing
- Connective Tissue Manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Istanbul University - Cerrahpasa
Back Pain Lower Back Chronic
Caudal Epidural Injection of Dextrose For Low Back Pain
Objective: The purposes of the study are to 1. Explore the immediate and short term (to 48 hour) analgesic potential of epidural D5W in comparison to normal saline. 2.
- Trial name
- NCT01547364
- Testing
- Saline, Dextrose
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Smigel, Liza, M.D.
Visceral Pain
Paragastric Neural Blockade and Laparoscopic Assisted Transversus Abdominis Plane Block on Visceral Pain After Surgery
after laparoscopic bariatric surgery, visceral pain (VP) remains a significant issue. VP causes autonomic symptoms, such as nausea and vomiting, and does not respond to conventional pain management methods that target incisional…
- Trial name
- NCT06973122
- Testing
- combined paragastric autonomic neural blockade and laparoscopic assisted transversus abdominis plane block, laparoscopic assisted transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 127 people
- Sponsor
- Alexandria University
Fibromyalgia
Effectiveness of Pain Neuroscience Education and Strength Training in Fibromyalgia
The main goal of this study is to get to know if applying both, pain neuroscience education (PNE) plus strength training (ST) will reduce the pain of fibromyalgia (FM).
- Trial name
- PNE-ST-FM (NCT04855851)
- Testing
- PAIN NEUROSCIENCE EDUCATION AND STRENGTH TRAINING, USUAL CARE
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Manuel Rebollo Salas
Neck Pain, Pain
Effects of Music Therapy in Chronic Neck Pain
This study aims to investigate the effects of music therapy on pain, cervical position sense, and balance in individuals with chronic neck pain.
- Conditions
- Neck Pain, Pain, Music Therapy
- Trial name
- NCT07658729
- Testing
- Music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Phythoterapy, Venipuncture Site Numbness
Antiseptic and Analgesic Action Acmella Oleracea Skin: Randomized Clinical Trial
Context: Research on natural products with therapeutic, analgesic or antimicrobial purpose should be encouraged to create new drugs.
- Conditions
- Phythoterapy, Venipuncture Site Numbness, Antimicrobial, Analgesic
- Trial name
- NCT02792972
- Testing
- A. oleracea, 70% alcohol
- Volunteers
- 60 people
- Sponsor
- Ana Beatriz Alkimim Teixeira Loyola
Neck Pain, Low Back Pain
Effects of Percutaneous Peripheral Nerve Stimulation on Neck and Low Back Pain
Percutaneous Peripheral Nerve Stimulation (pPNS) is a physical therapy technique, whose main objective is to treat neuro-musculo-skeletal signs and symptoms by applying a current to a peripheric nerve with a blunt dry needle.
- Trial name
- NCT06153875
- Testing
- Sensory Thresold, Burst High Frecuency, Theta-Burst Stimulation, Transcutaneous Electrical Nerve Stimulation
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Clinica Francisco Ortega Rehabilitacion Avanzada SL
Pain, Hypogonadism
Effects of Testosterone Replacement on Pain Sensitivity and Pain Perception
Naturally occurring opiates (endorphins) decrease testosterone levels by inhibiting the synthesis of gonadotropin releasing hormone (GnRH) and also inhibiting testosterone synthesis by the testes.
- Trial name
- TAP (NCT00351819)
- Testing
- AndroGel
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Boston University
Angina, Chronic Coronary Occlusion
XIENCE V/PROMUS Everolimus-Eluting Stent System Post-marketing Surveillance Protocol for Japan
The objectives of this post-marketing surveillance, conducted in Japan, is to know the frequency, type and degree of device malfunction, to assure the safety of the medical device, and to collect information on evaluation of the…
- Conditions
- Angina, Chronic Coronary Occlusion, Stent Thrombosis, Vascular Disease
- Trial name
- NCT01086228
- Testing
- XIENCE V / PROMUS stent
- Where
- 47 sites in Japan
- Volunteers
- 2,010 people
- Sponsor
- Abbott Medical Devices
Postoperative Pain
Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy
The aim of this study is to Investigate the analgesic efficacy of adding ketamine compared to neostigmine to local anesthetic in Ultrasound guided Serratus anterior plane block for patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT04544228
- Testing
- Serratus Anterior Plane Block Technique, General anesthesia, bupivacaine +ketamine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Plantar Fasciitis
Phase 2 DaxibotulinumtoxinA for Injection for the Management of Plantar Fasciitis
The specific aim of the study is to compare the safety and efficacy of a single administration of DaxibotulinumtoxinA for Injection versus placebo for managing plantar fasciitis.
- Trial name
- NCT03137407
- Testing
- Botulinum Toxins, Type A
- Where
- 5 sites in United States
- Volunteers
- 59 people
- Sponsor
- Revance Therapeutics, Inc.
Joint Dislocation, Perianal Abscess
Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in Adults
The purpose of this study is to describe the safety and efficacy of nitrous oxide administration for pain and anxiety before propofol in patients requiring any procedure under sedation in the Emergency Department.
- Conditions
- Joint Dislocation, Perianal Abscess, Abscess
- Trial name
- NCT02410707
- Testing
- Nitrous Oxide arm, Propofol, Oxygen
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Albert Einstein Healthcare Network
Pain
Implementing Genomics in Practice (IGNITE) Proof of Concept Study: Genotyping in Family Medicine Clinics
This study will examine the effect of having genotype information on pain management and pain control for patients treated in family medicine clinics.
- Trial name
- IGNITE (NCT02335307)
- Testing
- CYP2D6 genotyping, Pain assessment questionnaire, Physician assessment
- Where
- 11 sites in United States
- Volunteers
- 505 people
- Sponsor
- University of Florida
Liposuction, Bruising
Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction
The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction.
- Conditions
- Liposuction, Bruising, Inflammation, Pain, Postoperative
- Trial name
- CO2L001 (NCT06791577)
- Testing
- Carboxytherapy
- Where
- 3 sites in Brazil, Colombia and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Migraine in Children
A Survey Study to Assess the Accessibility of the Nerivio Device At School
This is a retrospective survey-study to assess the accessibility, preference, and frequency of adolescents using Nerivio by itself, in combination with pharmacological medications, or not at all, in the school setting.
- Trial name
- NCT06180577
- Testing
- Nerivio
- Where
- United States
- Volunteers
- 332 people
- Sponsor
- Theranica
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