Clinical trials: Pain, completed
Intestinal Diseases
Efficacy of Buscopan® in Comparison With 654-II (Anisodamine) in Acute Gastric or Intestinal Pain
The aim of the study is to assess the efficacy of Buscopan® (hyoscine butylbromide) in comparison to 654-II (anisodamine)in acute gastric or intestinal spasm-like pain.
- Trial name
- NCT01929044
- Testing
- 654-II (anisodamine), Buscopan® (hyoscine butylbromide)
- Where
- 20 sites in China
- Volunteers
- 299 people
- Sponsor
- Boehringer Ingelheim
Anesthesia, General, Pupil
Pupillometer as a Pain Index During General Anesthesia
This study evaluates the validity of pupil diameter as an indicator of pain during surgery under general anesthesia.
- Conditions
- Anesthesia, General, Pupil, Pain
- Trial name
- NCT04062864
- Testing
- Pupil size
- Where
- South Korea
- Volunteers
- 35 people
- Sponsor
- Seoul National University Hospital
Irritable Bowel Syndrome
Fructose and Fructans in Irritabla Bowel Syndrome
The purpose of the study is to investigate if patients with Irritable Bowel Syndrome (IBS) who also report bloating are more likely to report clinically important gastrointestinal symptoms after consuming fructose or fructans…
- Trial name
- FABS (NCT01776853)
- Testing
- Glucose, Fructose, Fructans
- Where
- United Kingdom
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Myocardial Injury After Non-cardiac Surgery, Abdomen, Acute
Troponin I Level and Mortality in Acute Abdominal Surgery
The goal of this prospective cohort study is to estimate the incidence of myocardial injury after non-cardiac surgery (MINS) in patients undergoing acute high-risk abdominal surgery.
- Trial name
- NCT05933837
- Testing
- Troponin I
- Where
- Denmark
- Volunteers
- 341 people
- Sponsor
- Nordsjaellands Hospital
Angina Pectoris, Unstable Angina
Pilot Study of Hemoglobin Based Oxygen Therapeutics in Elective Coronary Revascularization
The purpose of this study is to assess the safety and feasibility of a novel oxygen carrying solution, HBOC-201, in the setting of PCI for Acute Coronary Syndromes from randomization til hospital discharge.
- Conditions
- Angina Pectoris, Unstable Angina, Myocardial Infarction
- Trial name
- NCT00317512
- Testing
- Percutaneous Coronary Revascularization, Hemoglobin-Based Oxygen Carrier-201 (HBOC-201), Voluven
- Where
- 6 sites in Belgium, Germany and 1 more
- Volunteers
- 45 people
- Sponsor
- Biopure Corporation
Pain, Stress
Efficacy of Audio-Visual-Perception-Enhancement (AVWF®) Method in Chronic Pain Patients
It is anticipated that Audio-Visual-Perception-Enhancement (AVWF®) method leads to pain reduction and a decrease of inflammatory markers in chronic pain patients.
- Trial name
- NCT03776019
- Testing
- AVWF device
- Where
- Austria
- Volunteers
- 57 people
- Sponsor
- Klinikum Klagenfurt am Wörthersee
Cerebral Palsy, Hip Dysplasia
Peri-operative Use of a Pain Injection in Pediatric Patients With Cerebral Palsy
Pain management in pediatric patients presents a difficult challenge. Unlike adults, pediatric patients often cannot communicate their pain management needs clearly.
- Conditions
- Cerebral Palsy, Hip Dysplasia, Pain, Postoperative
- Trial name
- NCT04074265
- Testing
- Ropivacaine injection, normal saline
- Where
- 4 sites in United States
- Volunteers
- 34 people
- Sponsor
- University of California, Los Angeles
Interstitial Cystitis
Intravesicular Onabotulinumtoxin A in Interstitial Cystitis
The purpose of this research study is to identify the optimal usage of Onabotulinumtoxin A in interstitial cystitis. Onabotulinumtoxin A, more commonly known by the trade name Botox®, is a medication that comes from the bacteria…
- Trial name
- NCT02297100
- Testing
- Onabotulinumtoxin A, injections upper aspect of trigone of urinary bladder, injections on posterior bladder wall excluding the trigone
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Wake Forest University Health Sciences
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Acute Pain
A Clinical Study in Healthy Subjects Which Aims to Investigate the Safety, the Tolerability and the Effects of GRT0151Y and How the Compound is Taken up and Excreted From the Body
The aim of this clinical study in healthy participants is to investigate the safety and tolerability of GRT0151Y after multiple oral intake of different increasing doses and to evaluate the pharmacological effects (action of the…
- Trial name
- NCT03761407
- Testing
- 100 mg GRT0151Y, 125 mg GRT0151Y, 150 mg GRT0151Y
- Where
- France
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Pilonidal Sinus of Natal Cleft
Long-term Outcome After Pit-pick for Simple Pilonidal Sinus Disease
Single-center cohort study of long-term results after pit-pcik for pilonidal sinus disease.
- Trial name
- NCT05027607
- Testing
- Bascom's pit-pick
- Where
- Denmark
- Volunteers
- 158 people
- Sponsor
- Nordsjaellands Hospital
Virtual Reality, Immersive Virtual Reality
Immersive Versus Passive Virtual Reality on Upper Limb Pain and Range of Motion in Pediatric Burn
The purpose of the present study was to declare the difference between using immersive virtual reality vs passive virtual reality on pain management and improvement of ROM post physiotherapy exercise and mobilization sessions in…
- Conditions
- Virtual Reality, Immersive Virtual Reality, Pediatric Burn, Passive Virtual Reality
- Trial name
- NCT06612892
- Testing
- Virtual reality games in immersive VR modality, Virtual reality show in passive VR modality:, traditional physiotherapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pain
Effects of a Peripheral Nerve Block on Biomarkers of Pain and Inflammation
The purpose of this study is to determine the effect of a local anesthetic nerve block on markers of inflammation and pain after a sunburn.
- Trial name
- NCT00780936
- Testing
- femoral nerve block
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Achilles Tendinopathy, Pain
Effectiveness of Dry Needling of the Gastrocnemius Muscle VS Electrolysis in Subjects With Achilles Tendinopathy
Achilles tendinopathy is the injury that primarily occurs in athletes and people who engage in repetitive activities that involve the calf muscles, such as running, jumping, and sudden acceleration and deceleration movements.
- Trial name
- NCT06080334
- Testing
- Dry needling, Electrolysis
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Universidad Católica de Ávila
Rotator Cuff Injury, Pain
Pre-emptive Opioid Treatment to Prevent Rebound Pain After Arthroscopic Rotator Cuff Repair and/or Acromioplasty Under General Anesthesia and Interscalene Block
Arthroscopic shoulder rotator cuff repair and acromioplasty are associated with severe postoperative pain. The interscalene block (ISB) is commonly used for this type of surgery, providing analgesia by anesthetizing the nerves…
- Trial name
- NCT02939209
- Testing
- Hydromorphone Hcl 2Mg Tab
- Where
- 2 sites in Canada
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Vishal Uppal
Pain
Duration of Skin Numbing Effect Created by the S-Caine™ Peel
S-Caine™ Peel (lidocaine 7% and tetracaine 7% cream) is a new skin numbing cream made of lidocaine and tetracaine. The purpose of this study is to evaluate and measure the length of time the S-Caine Peel numbs the skin, when…
- Trial name
- NCT00110253
- Testing
- S-Caine™ Peel (lidocaine and tetracaine cream 7%/7%)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- ZARS Pharma Inc.
Acute Pain Due to Trauma, Analgesia
Timecost of Intranasal Versus Intravenous Analgesia in Traumatic Pain
Prehospital treatment of acute traumatic pain is common in military practice. Analgesics are usually administered intravenously (IV).
- Trial name
- NCT06351137
- Testing
- Intravenous administration, Intranasal administration
- Where
- Netherlands
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Patellofemoral Pain Syndrome
Trigger Point Dry Needling In Patient With Patellofemoral Pain Syndrome
This study intends to determine the effects of trigger point dry needling in patients with Patellofemoral pain Syndrome.
- Trial name
- NCT03966937
- Testing
- Dry needling, Control
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Shoulder Arthroscopy, Pain
Intravenous Dexamethasone on Supraclavicular Brachial Plexus Block for Shoulder Arthroscopy
Previous studies have confirmed that IV dexamethasone prolongs brachial plexus blocks. However, these studies only used fixed doses of IV dexamethasone at relatively high doses, which could potentially lead to increased glucose…
- Trial name
- SCB & IV Dex (NCT02688530)
- Testing
- IV Saline, IV Dexamethasone 4mg, IV Dexamethasone 6mg
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Osteo Arthritis Shoulders
MONOVISC for Shoulder Joint Pain Relief Due to Osteoarthritis
Obtain real world, post market data to confirm the clinical improvement and safety in patients treated with a single injection of MONOVISC for the symptomatic relief of osteoarthritis in the shoulder joint.
- Trial name
- NCT04204265
- Testing
- Monovisc
- Where
- 4 sites in Czechia, Poland
- Volunteers
- 25 people
- Sponsor
- Anika Therapeutics, Inc.
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