Clinical trials: Pain, open to volunteers
Percutaneous Internal Ring Suturing, Pain Management
Comparison of the Postoperative Analgesic Effects of RSB and CEB in Pediatric Patients Scheduled for Percutaneous Internal Ring Suturing
Inguinal hernia is one of the most common surgical pathologies in children, and the minimally invasive percutaneous internal ring suturing (PIRS) technique is widely preferred.
- Trial name
- NCT07147062
- Testing
- Rectus Sheath Block, Caudal Epidural Block
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Diskapi Yildirim Beyazit Education and Research Hospital
Postoperative Pain
Postoperative Analgesic Effectiveness of Fascial Plane Blocks in Breast Surgery
This prospective, single-center observational study will compare postoperative pain control in adults undergoing elective breast surgery.
- Trial name
- NCT07830446
- Testing
- Rhomboid intercostal plane block, Serratus posterior superior intercostal plane block, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Headache, Migraine
Headache and Hormone Use Among Transgender Population in Thailand: A Cross-Sectional Online Study
The goal of this observational study is to learn how common headache and migraine are and to describe headache patterns among transgender adults in Thailand.
- Trial name
- H-TRANS (NCT07817446)
- Testing
- gender-affirming hormone therapy, Gender-Affirming Surgery, HIV Pre-Exposure Prophylaxis
- Where
- Thailand
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Forward Head Posture, Neck Pain
Forward Head Posture Correction on Cerebral Oxygenation During Dual-task in Symptomatic Subjects
This study aims to investigate the effects of forward head posture correction on neck pain, brain activity, and cognitive-motor performance.
- Trial name
- FHP (NCT07565688)
- Testing
- Forward Head Posture Correction
- Where
- United Arab Emirates
- Volunteers
- 45 people
- Sponsor
- University of Sharjah
Patellofemoral Pain Syndrome
Core Stability Exercises Versus Proprioceptive Training on Pain and Function in Patients With Patellofemoral Pain Syndrome
This study will be conducted to investigate the effect of core stability exercises versus proprioceptive training in patients with patellofemoral pain syndrome.
- Trial name
- PFPS (NCT07664566)
- Testing
- Core Stability Exercises, Proprioceptive Training, traditional therapy
- Volunteers
- 63 people
- Sponsor
- Cairo University
Chronic Pain
Assessing the Efficacy of an Acceptance-Based Digital Intervention for Veterans With Chronic Pain
Pain has been identified as among the most frequent presenting medical complaints, in particular within primary care for Veterans.
- Trial name
- VACT-CP (NCT06058624)
- Testing
- Veteran ACT for Chronic Pain (VACT-CP), Online Pain School
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS)
Regenerative Medicine for Joint Hypermobility and Instability
This clinical trial is designed to evaluate whether a stepwise injection-based treatment approach can reduce pain and improve function in adults with joint hypermobility, connective tissue laxity, and joint instability.
- Conditions
- Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint Instability
- Trial name
- NCT07688096
- Testing
- Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational)
- Volunteers
- 100 people
- Sponsor
- Manhattan Pain Medicine, PLLC
Chronic Low Back Pain
The Effect of ESWT Added to Conservative Treatment on Pain, Disability, and Ultrasonographic Outcomes in Chronic Low Back Pain
Chronic low back pain (CLBP) is a major public health concern worldwide, leading to reduced quality of life and significant work loss.
- Trial name
- ESWT (NCT07132762)
- Testing
- Radial Extracorporeal Shock Wave Therapy, Conventional rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Pamukkale University
Piriformis Syndrome, Exercise Training
Telerehabilitation vs. Home Exercise in Piriformis Syndrome: A Comparative Study
The aim of this study is to compare the effects of asynchronous telerehabilitation and home exercise programs on pain, fear of pain, functionality, and performance in individuals with piriformis syndrome.
- Conditions
- Piriformis Syndrome, Exercise Training, Telerehabilitation
- Trial name
- PIRI-REHAB (NCT07502573)
- Testing
- Home exercise programme, telerehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hacettepe University
Postoperative Pain
US Guided EOI Block Versus ESPB for Postoperative Analgesia in Laparoscopic Cholecystectomy
To compare the efficacy of USG-guided bilateral External oblique intercostal (EOI) block with Erector spinae plane block (ESPB) for post-operative analgesia after laparoscopic cholecystectomy with a hypothesis that both External…
- Trial name
- NCT05272280
- Testing
- External oblique intercostal (EOI) block, Erector spinae plane block (ESPB)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Postoperative Pain
The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery
This study aimed to assess the effectiveness of Coenzyme Q10 in preventing both acute and chronic pain following thoracoscopic surgery, with a focus on its potential benefits in reducing the incidence and severity of pain.
- Trial name
- NCT06743802
- Testing
- Coenzyme Q10
- Where
- China
- Volunteers
- 264 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Surgical Stress Response, Stress Physiological
Feasibility of Breathwork Intervention With Older Adults After Knee Surgery
Postoperative complications after surgical procedures, including following total knee arthroplasty (TKA), have a negative impact on the health and well-being of surgical patients.
- Conditions
- Surgical Stress Response, Stress Physiological, Stress Physiology, Stress Psychological
- Trial name
- NCT07464860
- Testing
- A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Alzheimer Disease, Dementia
Music for Pain and Dementia
This study aims to provide mechanistic insights into how group drumming as a music-based intervention (MBI) affects pain responses and nociceptive function in individuals with Alzheimer's Disease (AD), mild dementia or mild…
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment, Peer-bonded Caregiver
- Trial name
- Music4Pain (NCT07602283)
- Testing
- Drumming session, Music-listening session
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Yale University
Myofascial Pain Syndrome
COMPARISON OF THREE TREATMENT MODALITIES IN MYOFASCIAL PAIN SYNDROME
This study aims to compare the effectiveness of dry needling, extracorporeal shock wave therapy (ESWT), and pulsed radiofrequency (PRF) in patients with chronic musculoskeletal pain.
- Trial name
- MPS-TREAT (NCT07511751)
- Testing
- Dry Needling, Extracorporeal Shock Wave Therapy, Pulsed radiofrequency(PRF)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- ALİEMAN
Persistent Spinal Pain Syndrome Type 2 (PSPS-T2), Lower Spine, Spinal Cord Sensitivity to Neurostimulation
Neurophysiological Effects of Medication Tapering During Treatment With Spinal Cord Stimulation
This study is being conducted in patients who will receive a spinal cord stimulator. This device helps manage chronic neuropathic pain in the trunk and/or limbs.
- Conditions
- Persistent Spinal Pain Syndrome Type 2 (PSPS-T2), Lower Spine, Spinal Cord Sensitivity to Neurostimulation, Neurophysiological Sensitivity to Spinal Cord Stimulation
- Trial name
- NCT07413731
- Testing
- Spinal Cord Stimulation with Evoke Closed-Loop System
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Brai²n
Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis
Does a Virtual Program for Pelvic Pain Improve Pain and Sexual Outcomes in Individuals With Provoked Vestibulodynia?
The goal of this clinical trial is to learn if a 3-month online pelvic health program works to improve pain and sexual wellbeing in adult women with chronic genital pain.
- Conditions
- Vulvodynia (Chronic Vulvar Pain), Vulvar Vestibulitis, Vestibulodynia, Provoked Vestibulodynia
- Trial name
- PVD (NCT06999395)
- Testing
- Virtual online pelvic health program
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Queen's University
Neck Pain Chronic
Exercise and Chronic Mechanical Neck Pain
This Randomized Clinical Trial will be conducted at Riphah Rehabilitation and Research Center and spans 4 weeks. Non-probability Convenient sampling will be used to collect the data.
- Trial name
- NCT07026019
- Testing
- Bruegger's relief exercise, Multimodal exercise program
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
Postoperative Pain
RADA16 for Adult Tonsillectomy
The purpose of the research is to determine if RADA16 (also known as PuraStat®, PuraGel®, or PuraSinus®) improves patient outcomes following tonsillectomy procedures.
- Trial name
- NCT07060495
- Testing
- RADA16 hydrogel
- Where
- 2 sites in United States
- Volunteers
- 134 people
- Sponsor
- Rutgers, The State University of New Jersey
Cutaneous Melanoma, Merkel Cell Carcinoma
EMLA Topical Cream for Treatment of Pain in Patients Receiving Intra-Dermal Technetium 99 Injections for Lymphoscintigraphy for Skin Cancers
This phase II trial tests how well EMLA topical cream works in treating pain in patients with skin cancers receiving Technetium 99 injections for a lymphoscintigraphy mapping procedure.
- Conditions
- Cutaneous Melanoma, Merkel Cell Carcinoma, Skin Squamous Cell Carcinoma
- Trial name
- NCT06223659
- Testing
- Eutectic Mixture of Local Anesthetics, Questionnaire Administration
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Pain, Itch
Topographical Distribution of Itch and Pain Receptors
The experiment consists of three experimental sessions conducted on three consecutive days. In all experimental sessions, the participant will fill in a series of questionnaires about how you perceive itch and pain, and about…
- Trial name
- NCT07122973
- Testing
- Histamine, Cowhage, Capsaicin 8% Patch
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aalborg University
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