Clinical trials: Pain After Abdominal Surgery
Opioid Use, Auriculotherapy
Auriculo-Nerve Stimulation on Post-Operative Opioid Requirement
The NSS-2 BRIDGE® device (NSS stands for Neuro-Stimulation System) is a disposable device that stimulates the branches of cranial nerves and of the superficial cervical plexus innervating the ear.
- Conditions
- Opioid Use, Auriculotherapy, Pain, Abdominal, Cancer Pain
- Trial name
- NCT05506878
- Testing
- NSS-2 BRIDGE
- Where
- 4 sites in United States
- Volunteers
- 286 people
- Sponsor
- Jacques E. Chelly
Inguinal Hernia, Primary
The Outcome After Lichtenstein Operation vs. ProGrip Patch Repair of Inguinal Hernia
For the present study, 400 consecutive men with unilateral primary inguinal hernia are randomized to Lichtenstein repair using either light weight polypropylene mesh (38g/m2) or light weight ProGrip mesh.
- Conditions
- Inguinal Hernia, Primary, Unilateral
- Trial name
- NCT01026935
- Testing
- Open inguinal hernia repair
- Where
- 2 sites in Finland
- Volunteers
- 398 people
- Sponsor
- Helsinki University Central Hospital
Acute Pain Following a Total Abdominal Hysterectomy
A Study of MK0663/Etoricoxib for Post-Abdominal Hysterectomy Surgery Pain (0663-097)(COMPLETED)
The purpose of this study is to evaluate the efficacy and safety of etoricoxib compared to placebo in the treatment of postoperative pain associated with total abdominal hysterectomy.
- Trial name
- NCT00788710
- Testing
- etoricoxib (MK0663) 120 mg, etoricoxib (MK0663) 90 mg
- Volunteers
- 430 people
- Sponsor
- Organon and Co
Kidney Transplantation
Does an Abdominal Wall Nerve Block During Surgery Help Reduce Pain From Kidney Transplantation?
This is a randomized, placebo controlled, double blind study to determine the effectiveness of a Transversus Abdominis Plane (TAP) block for reducing postoperative pain and opioid use in kidney transplant recipients.
- Trial name
- NCT05280197
- Testing
- TAP block, liposomal bupivacaine plus free bupivacaine, normal saline
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- The Cleveland Clinic
Abdominal Surgery
Therapeutic Effects of Pranayama Breathing Technique and Deep Breathing Exercises on Pain and Anxiety After Abdominal Surgery
This study will be conducted to evaluate the therapeutic effects of pranayama breathing technique and deep breathing exercises on pain and anxiety after abdominal surgery.
- Trial name
- NCT07164118
- Testing
- Pranayama Breathing Exercise, Deep Breathing Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Cukurova University
Inguinal Hernia
M-Tapa vs OSTAP for Laparoscopic Inguinal Hernia Repair Surgery
Inguinal hernia repair is the most common of abdominal surgical procedures and is usually performed laparoscopically. Many factors play a role in the pain that develops after surgery and is generally considered to be visceral…
- Trial name
- NCT05476510
- Testing
- Postoperative management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Pain, Postoperative
Efficacy and Safety of IV Diclofenac (DIC075V) for Pain After Abdominal or Pelvic Surgery
This study will compare repeated intermittent IV dosing of diclofenac in patients with moderate to severe post-surgical pain from abdominal or pelvic surgery.
- Trial name
- NCT00448110
- Testing
- Intravenous Diclofenac (DIC075V), Intravenous Ketorolac
- Where
- 14 sites in United States
- Volunteers
- 331 people
- Sponsor
- Javelin Pharmaceuticals
Postoperative Pain, Acute, Ventral Hernia
Study Exploring the Effect of Music on Pain After Ventral Hernia Surgery
The purpose of this study is to assess whether listening to music during surgery has an effect on pain or anxiety after surgery.
- Conditions
- Postoperative Pain, Acute, Ventral Hernia, Hernia Abdominal Wall, Surgery
- Trial name
- NCT05374096
- Testing
- Patient-Chosen Music
- Where
- United States
- Volunteers
- 321 people
- Sponsor
- The Cleveland Clinic
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Post-Dural Puncture Headache
Trans-nasal Sphenopalatine Ganglion Block Versus Ultrasound-guided Bilateral Greater and Lesser Occipital Nerve Block for Management of Post-Dural Puncture Headache.
Post-Dural Puncture Headache (PDPH) is a complication associated with spinal anesthesia. While conventional treatments are available, the Epidural Blood Patch (EBP) is considered the gold standard.
- Trial name
- TNSPGB /GALONB (NCT06705244)
- Testing
- Trans-nasal sphenopalatine nerve block, Greater and lesser occipital nerve block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Urologic Surgical Procedure
Minimizing Post-surgical Pain and Narcotic Administration Through Cryotherapy
Postoperative pain is an unavoidable consequence of open abdominal surgery. Although cryotherapy, the application of ice to a surgical wound site, has been shown to be effective in reducing postoperative pain in orthopedic…
- Trial name
- Ice (NCT01974882)
- Testing
- Ice pack
- Where
- 2 sites in United States
- Volunteers
- 55 people
- Sponsor
- Viraj Master
Pain, Postoperative
Acetaminophen vs Placebo for Postoperative Analgesia After Abdominal Surgery
This study investigates whether oral acetaminophen, when added to standard pain management, reduces opioid use and pain after major abdominal surgery, compared to a placebo (inactive pill).
- Trial name
- NCT07720791
- Testing
- Acetaminophen
- Volunteers
- 1,504 people
- Sponsor
- Konya City Hospital
Post Abdominal Surgery Pain
A Study Evaluating the Overall Pain Relief and Safety of Intravenous (IV) CR845 in Patients Undergoing Abdominal Surgery
The study schedule is comprised of a 14-day Screening Period, a treatment period and an observation period. All eligible subjects will be randomized into one of 3 treatment groups (1 of 2 dose levels or matched placebo).
- Trial name
- NCT02542384
- Testing
- CR845 IV 1 mcg/kg, CR845 IV 0.5 mcg/kg
- Where
- 23 sites in United States
- Volunteers
- 451 people
- Sponsor
- Cara Therapeutics, Inc.
Post Operative Pain, Hemodynamic Instability
Intra-abdominal Pressure and Insufflator Effects in Robotic Surgery
The main aim of this study is to compare the perioperative effects of different intra-abdominal pressures and different insufflators in patients undergoing robotic surgery at a 30-45 degree trendelenburg position.
- Conditions
- Post Operative Pain, Hemodynamic Instability, Hypercapnia, Complication,Postoperative
- Trial name
- NCT06132490
- Testing
- Valveless Insufflator with 12 mmHg intra-abdominal pressure, Valveless Insufflator with 8 mmHg intra-abdominal pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Koç University
Abdominal Neoplasms
Continuous Pre-peritoneal Wound Infiltration Versus Epidural Analgesia in Cancer Surgery
the investigators aim is to investigate the effect of continuous preperitoneal bupivacaine wound infiltration versus epidural analgesia on the inflammatory cytokines response following radical cytectomy
- Trial name
- NCT03002909
- Testing
- epidural catheter, preperitoneal catheter
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Chronic Postoperative Pain
Persistent Postoperative Pain After Major Emergency Abdominal Surgery
Perioperative pain is one of the most significant complaints and problems for patients undergoing major open surgery. Pain after surgery carry an abundance of consequences such as reduced mobilization, reduced nutrition intake…
- Trial name
- NCT04508465
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- Zealand University Hospital
Abdominal Massage, Enteral Nutrition
Effect of Abdominal Massage on Gastrointestinal Symptoms After Head and Neck Cancer Surgery
This study aimed to evaluate whether abdominal massage could reduce abdominal pain, constipation, and gas/bloating in patients receiving enteral nutrition through a nasogastric tube after surgery for head and neck cancer.
- Conditions
- Abdominal Massage, Enteral Nutrition, Nasogastric Feeding, Head and Neck Surgery
- Trial name
- HNC-AM (NCT07889011)
- Testing
- Abdominal Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Maltepe University
Pain After Surgery
RISS Versus Lower Thoracic ESP Block for Analgesia After Laparoscopic Abdominal Surgery: A Randomized Trial
The goal of this clinical trial is to investigate the analgesic efficacy of ultrasound-guided Romboid Intercostal and Subserratus (RISS) block versus lower thoracic Erector Spinae Plane (ESP) block after laparoscopic abdominal…
- Trial name
- NCT07593300
- Testing
- Group A (n=35): Ultrasound-guided RISS block (RISS):, Group B (n=35): Ultrasound-guided lower thoracic ESP block
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Postoperative Pain
Safety and Efficacy of Multiple Doses of Intranasal Ketorolac in Postoperative Pain Following Major Abdominal Surgery
Ketorolac has been marketed for several years in other forms (tablet and injectable) for the short-term relief of pain. This study will test whether a new dosage form (nasal spray) containing ketorolac is effective at relieving…
- Trial name
- NCT00266786
- Testing
- Intranasal Ketorolac Tromethamine
- Where
- 6 sites in United States, New Zealand
- Volunteers
- 321 people
- Sponsor
- Egalet Ltd
Post-Operative Pain
A Trial Evaluating the Efficacy and Safety of the Sublingual Sufentanil Tablet 30 mcg for Post-Operative Pain After Abdominal Surgery
The purpose of this study is to compare the efficacy and safety of the sublingual Sufentanil Tablet (ST) 30 mcg to the sublingual Placebo Tablet (PT) for the short-term management of moderate-to-severe acute post-operative pain…
- Trial name
- NCT02356588
- Testing
- Sufentanil Tablet 30 mcg
- Where
- 4 sites in United States
- Volunteers
- 161 people
- Sponsor
- Talphera, Inc