Clinical trials: Pain After Surgery
Post Operative Pain Management
Efficacy of Erector Spinae Plane Block Versus Subcostal Transversus Abdominis Plane Block in Laparoscopic Nephrectomy
The investigators hypothesize that erector spinae plane block is better than subcostal transversus abdominis plane block regarding postoperative pain management.
- Trial name
- NCT06670508
- Testing
- Subcostal Transversus Abdominis Plane block, Erector Spinae Plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Cairo University
Esketamine, Pregabalin
Esketamine Combined With Pregabalin on Acute Postoperative Pain in Patients Undergoing Resection of Spinal Neoplasms.
Postsurgical pain is now known to be one of the most common and difficult-to-treat complications of surgery. severe postoperative pain can significantly impair patients' quality of life, social functioning and contribute to…
- Conditions
- Esketamine, Pregabalin, Acute Postoperative Pain, Neurosurgical Procedures
- Trial name
- NCT05096468
- Testing
- S-ketamine and pregabalin
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Beijing Tiantan Hospital
Pain
Post-surgical Pain Assessment in Children: Roles of Skin Conductance and Genomics
Pain assessment in infants and toddlers is quite challenging since children in these populations are nonverbal or preverbal and cannot describe the presence and severity of pain that they perceive.
- Trial name
- NCT02534168
- Testing
- Skin conductance monitor for measuring skin conductance
- Where
- United States
- Volunteers
- 162 people
- Sponsor
- Milton S. Hershey Medical Center
Postoperative Pain
Flurbiprofen Axetil for Uterine Contraction Pain
Uterine contraction pain is a common problem after abortion. Optimal analgesic for such suffering is still needed to be guaranteed.
- Trial name
- FAUCOP (NCT00725218)
- Testing
- Saline, Flurbiprofen Axetil
- Where
- China
- Volunteers
- 97 people
- Sponsor
- Nanjing Medical University
Thoracic, Pain, Postoperative
Intercostal Nerve Block for Pain Management After Uniportal Video-assisted Thoracoscopic Surgeries
The goal of this clinical trial is to compare the safety and effectiveness of the three intercostal nerve blocks used in pain management in uniportal (one port) thoracoscopic surgeries: internal intercostal nerve blocks (ICNB)…
- Conditions
- Thoracic, Pain, Postoperative, Analgesia, Satisfaction, Patient
- Trial name
- VATS (NCT06838026)
- Testing
- External Intercostal Nerve Block, Internal Intercostal Nerve Block, Intercostal Catheter
- Where
- 2 sites in Palestinian Territories
- Volunteers
- 90 people
- Sponsor
- Al-Quds University
Postoperative Pain
Comparison of Genicular Nerve Block and Intraarticular Injection for Postoperative Pain in Knee Arthroscopy
This prospective double-blinded randomized study will be conducted to compare ultrasound-guided intra-articular injection and ultrasound-guided genicular nerve block for postoperative analgesia after knee arthroscopy.
- Trial name
- NCT04656743
- Testing
- intra-articular injection, genicular nerve block
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Tanta University
Arthroplasty, Replacement, Hip
Multimodal Analgesic Regimen for Total Hip Arthroplasty: An Initiative to Minimize Postoperative Opioid Use
This study examines whether patients undergoing total hip replacement surgery can manage their pain effectively while using fewer opioid pain medications. Participants will be randomly assigned to one of two groups.
- Trial name
- NCT07672808
- Testing
- Standard Multimodal Analgesic Regimen with Opioid Prescription, Opioid-Reduced Multimodal Analgesic Regimen with Printed Prescription
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Henry Ford Health System
Facial Pain, Pain, Postoperative
Effectiveness of Alveogyl and Cutanplast Dressing on Postoperative Pain Following Tooth Extraction: A Clinical Trial
This study aims to assess the post-dental extraction pain following the application of two different dressing materials. Alvogyl® and Absorbable gelatin sponges
- Conditions
- Facial Pain, Pain, Postoperative, Pain, Orofacial
- Trial name
- NCT04779476
- Testing
- Socket Dressing
- Where
- Saudi Arabia
- Volunteers
- 50 people
- Sponsor
- Riyadh Elm University
Spine Surgery, Pain After Surgery
Impact of NOL - Nociception Level Index Intraoperative Monitoring on Perioperative Outcomes in Spine Surgery - a Quality Improvement Pilot
The objective of this study is to evaluate the clinical impact of the NOL nociception level index monitoring on intraoperative and post operative patient outcomes and institutional metrics when used to guide intraoperative…
- Conditions
- Spine Surgery, Pain After Surgery, Anesthesia , Analgesia
- Trial name
- NCT07608276
- Testing
- NOL guided intraoperative analgesia
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Medasense Biometrics Ltd
Post-operative Pain
Reduction of Post-endodontic Pain After 3 Irrigation Regime
The goal of this research was to relate the occurrence of post-endodontic pain after single-visit RCT using there irrigating regime.
- Trial name
- RPEP (NCT03559140)
- Testing
- Applied saline solution at 2.5 oC (Cryotherapy group), Applied saline solution at 8oC (Cryotherapy ), Applied saline solution at room temperature (No cryotherapy)
- Where
- Mexico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Surgery
Lidocaine and Prevention of Chronic Pain
The study seeks to investigate a safe and inexpensive strategy to reduce persistent post-surgical pain that can affect up to 60% of patients undergoing surgical procedures.
- Trial name
- NCT01619852
- Testing
- Group L (lidocaine)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Northwestern University
Pharmacogenetics, Anesthesia
Perioperative Pharmacogenomic Testing
This is a single centre, prospective feasibility study and pilot randomised controlled trial of patients scheduled for elective intermediate or major non-cardiac surgery.
- Trial name
- PPGx (NCT05063838)
- Testing
- Pharmacogenomic optimisation of anaesthetic medications
- Where
- Australia
- Volunteers
- 200 people
- Sponsor
- Peter MacCallum Cancer Centre, Australia
Multimodal Analgesia, Nonsteroidal Anti-inflammatory Drugs
NSAID vs. Narcotics
This will be a single-center, prospective observational study. The study will compare post-operative pain scores and narcotic consumption between two groups of patients - one cohort will receive ibuprofen (Motrin) and Percocet…
- Trial name
- NCT02915055
- Testing
- Ibuprofen 600 mg, standard oxycodone/acetaminophen
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block
Analgesic Efficiency of SIPSPB vs ICNB in VATS Surgery
This study aims to evaluate the effectiveness of Serratus Posterior Superior Intercostal Plane (SPSIP) block compared to Intercostal Nerve (ICN) block in terms of postoperative pain control, reduction of opioid analgesic…
- Conditions
- Intercostal Nerve Block, Serratus Posterior Superior Intercostal Plane Block, Post-operative Pain Management, VATS
- Trial name
- NCT07577908
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kocaeli City Hospital
Ibuprofen, Ketorolac
IV Ibuprofen vs Ketorolac in Post Operative Pain in Colorectal Cancer Surgeries in Obese Patient
The aim of this study is to assess the Efficacy of IV Ibuprofen and Ketorolac in the Management of Postoperative Pain in obese patients Following abdominal cancer surgery.
- Conditions
- Ibuprofen, Ketorolac, Colorectal Cancer
- Trial name
- NCT05782608
- Testing
- IV ibuprofen, IV ketorolac
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Postoperative Pain
Efficacy of Ropivacaine Continuous Wound Instillation Versus Single Shot After Spine Fusion Surgery
Because local anesthetic infiltration has not been comparated to continuous infusion after spine fusion surgery, the investigators designed this study to determine whether this technique could enhance analgesia and improve…
- Trial name
- NCT00823576
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Inguinal Hernia, Laparoscopic Surgery
Functional Outcome After Groin Hernia Mesh Repair: Open Versus Laparoscopy
Background: Large acceptance of mesh reinforcement techniques in groin hernia repair lowered recurrence rates for all techniques. Recurrence rate alone is not the main quality criterion for hernia repair anymore.
- Conditions
- Inguinal Hernia, Laparoscopic Surgery, Pain, Sexual Dysfunction, Physiological
- Trial name
- GENINGHERNIA (NCT00625534)
- Testing
- Laparoscopic totally extraperitoneal inguinal hernia repair, Open tension free inguinal hernia mesh repair
- Where
- Switzerland
- Volunteers
- 260 people
- Sponsor
- University Hospital, Geneva
Post Operative Pain, Opioid Use
Optimizing Research Data Acquisition With Smart Pill Bottles
The goal of this clinical trial is to learn if smart pill bottles can be used as a tool to optimize data collection in clinical trials by increasing the quality of data collected and limiting the associated cost.
- Trial name
- SPB (NCT06522698)
- Testing
- Smart Pill Bottle
- Where
- Canada
- Volunteers
- 155 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Pelvic Organ Prolapse, Post Operative Pain
Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy
In the effort to reduce postoperative opioid use, there has been increasing interest in developing multimodal pain regimens to better manage postoperative pain while minimizing opioid use and their subsequent side effects that…
- Trial name
- NCT06309693
- Testing
- Quadratus Lumborum (QL) Block, Enhanced Recovery After Surgical (ERAS) Protocol
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Alabama at Birmingham
Chronic Postsurgical Pain
The Effect of Esketamine Combined With Pregabalin on Chronic Postsurgical Pain in Patients After Craniotomy.
Chronic postsurgical pain (CPSP), which is one of the most common and serious long term complication of surgery，occurs in approximately 10% of patients after a surgical procedure.
- Trial name
- NCT05160493
- Testing
- S-ketamine and pregabalin
- Where
- China
- Volunteers
- 246 people
- Sponsor
- Beijing Tiantan Hospital