Clinical trials: Pain Assessment
Hypertrophic Cardiomyopathy
Ranolazine for the Treatment of Chest Pain in HCM Patients
The purpose of RHYME is to evaluate the safety and efficacy of ranolazine in Hypertrophic Cardiomypathy patients with chest pain or dyspnea despite treatment with standard medical therapy.
- Trial name
- RHYME (NCT01721967)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Duke University
Surgical View, Shoulder Tip Pain
Evaluation of Low Pressure Pneumoperitoneum in Bariatric Surgery (ELOPES Study)
This is a prospective study whereby it involves patients who are planned for bariatric surgery. In the bariatric surgery procedure, pneumoperitoneum pressure will be the experimental aspect in this study.
- Conditions
- Surgical View, Shoulder Tip Pain, Abdominal Pain
- Trial name
- NCT03179111
- Testing
- Pneumoperitoneum Pressure
- Where
- Malaysia
- Volunteers
- 94 people
- Sponsor
- Universiti Putra Malaysia
Postoperative Pain
A Pharmacokinetic (PK) Study of Extended-Release Epidural Morphine in Upper Abdominal Surgery
The primary purpose of this study is to evaluate the effects of lidocaine/epinephrine test dose administration on the PK profile of a single epidural dose of DepoDur (extended-release epidural morphine) in patients undergoing…
- Trial name
- NCT00728832
- Testing
- DepoDur (extended-release epidural morphine)
- Volunteers
- 39 people
- Sponsor
- EKR Therapeutics, Inc
Root Canal Treatment, Post Operative Pain
A First in Human Study to Compare Feasibility of Inertial Cavitation Irrigation to SNI in Root Canal Treatment.
The study design is a single-center 2-arm randomized controlled clinical trial. 10 subjects (teeth) requiring a root canal treatment will be enrolled in 2 groups (5 in each group).
- Trial name
- NCT05374434
- Testing
- Conventional irrigation, Inertial cavitation
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Lumendo AG
Burn
VRH Pain Reduction During Burn Wound Care and Physical Therapy
Using Virtual Reality Hypnosis to relief pain and anxiety for burn patients.
- Trial name
- VRH (NCT00260221)
- Testing
- using VR hypnosis/distraction and audio hypnosis
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Oral Mucositis
Ozone Therapy for Cancer Therapy-Related Oral Mucositis
This retrospective observational study will evaluate clinical data already available from adult cancer patients who developed cancer therapy-related oral mucositis during radiotherapy and/or chemotherapy and who were managed in…
- Trial name
- OMUC-O3 (NCT07638904)
- Testing
- Combined Ozone-Based Oral Care Protocol
- Where
- Italy
- Volunteers
- 58 people
- Sponsor
- University of Pavia
Chronic Pain
Feasibility Study of an Online Self-management Program for Chronic Non-cancer Pain
Based on a mixed-methods design, the objective of this trial is to assess the feasibility and acceptability of the "Agir pour moi" program, an 8-week online self-management program for chronic non-cancer pain (CNCP).
- Trial name
- NCT05319652
- Testing
- Pain self-management program
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- CHU de Quebec-Universite Laval
Acute Low Back Pain
Efficacy and Safety of NVP-1203 in Patients With Acute Low Back Pain
The purpose of this study is to evaluate the efficacy and safety NVP-1203 in patients with Acute low back pain
- Trial name
- NCT03341832
- Testing
- NVP-1203, NVP-1203-R
- Where
- South Korea
- Volunteers
- 91 people
- Sponsor
- NVP Healthcare
Premature, Retinopaty of Prematurity
Pain and Comfort in the Examination of Retinopathy of Prematurity
This study is planned to be conducted in the Neonatal Intensive Care Unit using a double-blind, parallel-group, randomised controlled design to determine the effect of a pacifier dipped in breast milk on pain and comfort during…
- Trial name
- NCT07334652
- Testing
- Pacifier group
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Ataturk University
Chikungunya Fever
Effects of Auriculotherapy on Pain and Functional Capacity of Individuals With Chikungunya Fever
Chikungunya fever is an acute viral disease, transmitted by the mosquito (Aedes aegypti), that triggers pain and disabling rheumatic manifestations.
- Trial name
- NCT03090685
- Testing
- True auriculotherapy with seeds
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Universidade Federal do Ceara
Breast Cancer, Anesthesia
Pain Control in Breast Surgery: Analgesia, Opioid Consumption and Inflammatory Response Evaluation
The serratus anterior muscle plane (SAM) block associated with pectoral nerve block type I (PEC I) may be a safe and effective alternative for the intraoperative of breast surgery, since there is evidence of pain reduction.
- Trial name
- NCT02647385
- Testing
- Block with lidocaine for SAM and PEC I block
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital Sirio-Libanes
Exercise Induced Muscle Damage, Physical Activity
Walk It Off! the Influence of Physical Activity Level on the Recovery from Damaging Resistance Exercise
After completing novel activity or exercise we may experience exercise-induced muscle damage (EIMD), resulting in a period of reduced muscle function and delayed onset muscle soreness (DOMS).
- Conditions
- Exercise Induced Muscle Damage, Physical Activity, Inflammation, Exercise Recovery
- Trial name
- WIO (NCT06810271)
- Testing
- Eccentric resistance exercise
- Where
- Canada
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Chronic Low Back Pain, Self-Management
Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
This pilot project will provide an understanding of the contextual variables responsible for chronic low back pain. These variables include, genetic variation, pain sensitivity, reactivity, pain catastrophizing, perceived stress…
- Trial name
- PROPEL (NCT03637998)
- Testing
- Problem-solving Pain to Enhance Living Well (PROPEL)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Healthy Volunteers
Civamide Patch Safety, Tolerability and PK Study
To evaluate the tolerability of two different strengths of a Civamide Patch (0.0075% and 0.0150%) compared to the placebo patch and each other in healthy adult volunteers.
- Trial name
- NCT00758433
- Testing
- Zucapsaicin
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Winston Laboratories
Pomegranate (P. Granatum) Peel Compress
The Effect of Pomegranate (Punica Granatum L.) Peel Compress Application on Pain and Physical Function Status
Osteoarthritis is the most common type of arthritis among rheumatologic diseases. Complementary therapies are one of the effective methods for pain control. This study was planned as a randomized controlled experimental study.
- Trial name
- Pomegranate (NCT06034106)
- Testing
- Pomegranate (Punica granatum) peel compress, Hot compress
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Liver Cancer, Pancreas Cancer
A Clinical Trial to Evaluate Safety and Efficacy of Endovascualr Denervation in Treatment of Cancer Pain
A prospective, multicenter, self-control clinical trial aim to enroll 110 patients suffered from upper abdominal (liver, pancreas, stomach, etc.) cancers .
- Conditions
- Liver Cancer, Pancreas Cancer, Stomach Cancer, Bile Duct Cancer
- Trial name
- NCT04014478
- Testing
- Endovascular Denervation
- Volunteers
- 110 people
- Sponsor
- Shanghai Golden Leaf MedTec Co. Ltd
Pain Syndrome
Cervical Manual Therapy and Vagus Nerve Stimulation in Patients With Nonspecific Neck Pain
People with chronic neck pain are becoming more and more common in society every day.
- Trial name
- NCT06435364
- Testing
- Vagus nerve stimilation, Manual therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medipol University Hospital
Sickle Cell Disease
A Safety Study of Eptifibatide in Patients With Sickle Cell Disease
This study will evaluate the safety of eptifibatide in sickle cell patients and how well it works during the course of painful crises.
- Trial name
- NCT00834899
- Testing
- Eptifibatide
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of North Carolina, Chapel Hill
Acute, Post-operative Pain
Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ST-2427
This randomized, double-blind, placebo controlled, study will be conducted to evaluate the safety, tolerability, and pharmacokinetics of ST-2427.
- Trial name
- NCT04475198
- Testing
- ST-2427
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- SiteOne Therapeutics, Inc.