Clinical trials: Pain Control, open to volunteers
Complex Obstetric Surgery, Perioperative Pain Management
COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block
To assess the effect of intraoperative transversus abdominis plane (TAP) blocks on the amount of opioid pain medications expressed as morphine milliequivalents (MME) used postoperatively in patients who have undergone cesarean…
- Conditions
- Complex Obstetric Surgery, Perioperative Pain Management, Cesarean Delivery, Postoperative Pain Control
- Trial name
- COMFORT (NCT06925152)
- Testing
- Bupivicaine intervention arm
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Tennessee
Postoperative Pain Control, Coronary Artery Disease
Serratus Anterior Plane Block for Recovery After Minimally Invasive CABG
Coronary artery bypass surgery is an important treatment method for severe coronary heart disease. Among them, minimally invasive bypass surgery, although having less trauma, requires a small incision on the left chest.
- Trial name
- NCT07877532
- Testing
- Ultrasound-guided Serratus Anterior Plane Block with Ropivacaine, Ultrasound-guided Serratus Anterior Plane Block with Normal Saline
- Volunteers
- 168 people
- Sponsor
- Chinese PLA General Hospital
Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty
Perioperative Colchicine for TKA
This study is a prospective, randomized, double-blinded, placebo-controlled study of the drug colchicine in the acute postoperative period for patients who are undergoing a total knee arthroplasty (TKA).
- Conditions
- Osteoarthritis of Knee, Recovery Following Primary Total Knee Arthroplasty, Perioperative Pain Control
- Trial name
- NCT06936709
- Testing
- Colchicine 1.8 mg + 0.6 mg
- Volunteers
- 75 people
- Sponsor
- Geisinger Clinic
Ischemic Heart Disease (IHD), Off-pump Coronary Artery Bypass
Efficacy of Multiple Nerve Blocks on the Recovery of Patients Undergoing Off Pump CABG Surgeries
In cardiac surgery patients , effective pain control is crucial to support early extubation, mobilization, and cognitive recovery, yet systemic opioids carry substantial risks such as respiratory depression, delirium, and delayed…
- Conditions
- Ischemic Heart Disease (IHD), Off-pump Coronary Artery Bypass, Regional Block for Pain Control
- Trial name
- NCT07794527
- Testing
- regional nerve block with local anesthesia
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Chronic Neck Pain, Healthy (Controls)
Accessory Inspiratory Muscles in Chronic Neck Pain
This cross-sectional case-control study aims to investigate the ultrasonographic structural and functional characteristics of accessory inspiratory muscles in individuals with chronic non-specific neck pain and compare them with…
- Trial name
- AIM-CNP (NCT07782099)
- Testing
- Diaphragm Ultrasonography, Anterior Scalene Muscle Ultrasonography, Upper Trapezius Muscle Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kocaeli Sağlık ve Teknoloji Üniversitesi
Pulmonary Function, Post Operative Pain Control
Comparison of M-TAPA and ESPB for Postoperative Pulmonary Function After Laparoscopic Cholecystectomy
This prospective, randomized, controlled clinical trial aims to compare the effects of two ultrasound-guided fascial plane blocks, the Erector Spinae Plane Block (ESPB) and the Modified Thoracoabdominal Nerve Block through…
- Trial name
- NCT07666646
- Testing
- Modified thoracoabdominal nerve block through the perichondrial approach (M-TAPA), Erector spinae plane block (ESPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kayseri City Hospital
Fear is a Common Psychological Response Undergoing Medical Procedures,Act From Uncertainty, Anticipation of Pain, Loss of Control, Previous Negative Experiences
(Effect of Toy Nebulizer Versus Distraction Cards on Children's Fear and Parental Satisfaction During Nebulization Therapy: A Comparative Study
Goal To compare the effectiveness of a toy nebulizer versus distraction cards in reducing fear among children during nebulization therapy while improving parental satisfaction.
- Trial name
- NCT07417839
- Testing
- distraction card, Nebuliser toy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
Upper Limb Amputation, Postural Control
The Relationship Between Lost Extremity Percentage and Postural Control, Neck and Low Back Pain, Daily Living Activities, and Reaction Time in Individuals With Unilateral Upper Limb Amputation
This observational study aims to examine the relationship between the percentage of limb loss and functional outcomes in individuals with unilateral upper limb amputation.
- Conditions
- Upper Limb Amputation, Postural Control, Neck Pain, Low Back Pain
- Trial name
- NCT07677969
- Testing
- This is an observational study. No interventional procedures are performed. All assessments are non-invasive measurements.
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Hacettepe University
Labor, Second Stage, Vaginal Delivery
USE OF PERINEAL MIRROR DURING THE SECOND STAGE OF LABOR
Objective: This study was designed to evaluate the effect of perineal mirror use during the second stage of labor on the duration of the second stage, postpartum recovery, and perceived pain, support, and control levels during…
- Conditions
- Labor, Second Stage, Vaginal Delivery, Primiparity, Perineal Mirror Use
- Trial name
- NCT07659249
- Testing
- Perineal Mirror
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Opioid Use Disorder, Healthy Controls Group - Age and Sex-matched
Opioid Use Disorder and Pain
The goal of this observational study is to characterize the brain processes of pain avoidance learning dysfunctions in individuals with opioid use disorder (OUD).
- Trial name
- NCT06800703
- Testing
- follow up interviews for 12 months to determine opioid use
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Coronary Artery Bypass Graft (CABG), Chest Tubes
Chest Tube-Delivered Bupivacaine to Decrease Postoperative Pain After Cardiac Surgery
Background: After heart surgery, patients require temporary chest tubes - plastic drains placed inside the chest to prevent fluid building up around the heart and lungs.
- Conditions
- Coronary Artery Bypass Graft (CABG), Chest Tubes, Post Operative Pain Control
- Trial name
- FREEZE-B (NCT07643506)
- Testing
- 0.5% Bupivacaine without epinephrine, 10cc injection of normal saline (0.9%)
- Volunteers
- 60 people
- Sponsor
- University of Calgary
ADHD, PTSD
Trauma-adapted Yoga in Child & Adolescent Psychiatry.
The goal of this randomized clinical trial is to evaluate the efficacy of trauma-adapted yoga as a complementary intervention to care as usual in child and adolescents psychiatry clinics, in the population of adolescents with the…
- Conditions
- ADHD, PTSD, Quality of Life, Self-Control
- Trial name
- TAY-CAP (NCT06330779)
- Testing
- Trauma-adapted yoga
- Where
- Sweden
- Volunteers
- 180 people
- Sponsor
- University West, Sweden
Duration of Labor, Labor Pain
Effects of Midwife-guided biırth Affirmation Cards on Labor Process and Experience ın Primigravidas
The aim of this study is to evaluate the effects of midwife-guided birth affirmation cards on labor duration, pain level, fear of childbirth, perceived control, and perceived support in primigravidas.
- Conditions
- Duration of Labor, Labor Pain, Fear of Childbirth, Control (Internet Only)
- Trial name
- NCT07542392
- Testing
- Midwife-Guided Birth Affirmation Cards
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Musculoskeletal Pain, Fibromyalgia
Neural Mechanisms of Light Driven Analgesia
The goal of this study will be to understand the biological mechanisms that are responsible to light-driven analgesia. Light presented to the retina has been shown to have pain relieving properties in pre-clinical and clinical…
- Conditions
- Musculoskeletal Pain, Fibromyalgia, Healthy Controls Group - Age and Sex-matched
- Trial name
- NCT07245303
- Testing
- S-cone modulating visual stimulus, Equal Energy White Visual Stimulus, Green light visual stimulus (S-OFF)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Post Operative Pain Control, PONV
Effectiveness of Unilateral Transversus Abdominis Plane (TAP) Block vs Bilateral TAP Block in Patients Undergoing Laparoscopic Cholecystectomy.
In this study, patients undergoing laparoscopic cholecystectomy will be randomly divided into 2 groups after consent. Group A patients will be administered a one-sided (right unilateral) regional TAP block and group B patients…
- Trial name
- NCT07513012
- Testing
- Unilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine, Bilateral Transversus abdominis plane (TAP) block with 0.25 % bupivacaine
- Where
- Pakistan
- Volunteers
- 82 people
- Sponsor
- King Edward Medical University
Low Back Pain, Postural Control
Effectiveness of Pilates on Postural Correction, Core Strength and Flexibility in Younger Individuals With Non-specific Low Backache
The aim of this clinical trial is to study the effects of Pilates intervention versus conventional therapy on postural correction, core strength and flexibility in young individuals with complaint of non-specific low backache.
- Conditions
- Low Back Pain, Postural Control, Core Strength, Flexibility
- Trial name
- NCT07467070
- Testing
- Pilates, conventional therapy
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Health Sciences Lahore
Postoperative Pain, Sternotomy
Preoperative Deep Parasternal Intercostal Plane Block and Intraoperative Opioid Use in Cardiac Surgery
Median sternotomy is commonly used in cardiac surgery and is associated with significant intraoperative and postoperative pain, often requiring substantial opioid administration.
- Conditions
- Postoperative Pain, Sternotomy, Opioid Consumption, Intraoperative Pain Control
- Trial name
- NCT07315308
- Testing
- Deep Parasternal Intercostal Plane Block, Standard Multimodal Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Gaziantep City Hospital
Sedentary Behavior, Motor Control Impairment
Lumbar Stabilization Exercises in Sedentary Adults
This pilot randomized controlled trial will examine the effects of a four-week lumbar spine stabilization exercise program on motor control, dynamic balance, and quality of life in healthy sedentary adults.
- Conditions
- Sedentary Behavior, Motor Control Impairment, Quality of Life
- Trial name
- NCT07447167
- Testing
- Ergonomic and Stretching Instructions, Lumbar Stabilization Exercise Program
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of West Attica
Post Operative Pain Control
Efficacy of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Plane Block for Postoperative Pain Control Following Video-assisted Thoracoscopic Surgeries (VATS): Randomized Control Trial
The aim of the study is to compare the analgesic efficacy of Erector spinae plane block versus Serratus anterior plane block in patients undergoing video-assisted thoracoscopic surgeries.
- Trial name
- NCT07360028
- Testing
- Erector Spinae (ESP) Block with Bupivacaine (Marcaine®), Serratus anterior plane block (SAP)
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Oocyte Retrieival and Post Operative Pain Control, Acupuncture
ACU-TENS on Pain and Stress Reduction Before and During TUGOR
Objectives: To demonstrate the use of acupuncture-type transcutaneous electrical nerve stimulation (acu-TENS) during transvaginal ultrasound-guided oocyte retrieval (TUGOR) will reduce 50% of the intensity of pain experienced by…
- Trial name
- NCT06910540
- Testing
- Acu-TENS
- Where
- China
- Volunteers
- 144 people
- Sponsor
- Chinese University of Hong Kong