Clinical trials: Pain Control for Intrauterine Device Insertions
Contraception
Oral Ketorolac for Pain Relief During IUD Insertion
Ketorolac is a non-steroidal anti-inflammatory drug (NSAID), similar to ibuprofen but it is used to treat more severe pain. Ketorolac (Trade name: Toradol) is typically used after surgical procedures.
- Trial name
- NCT03031795
- Testing
- Ketorolac
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- OhioHealth
Contraception
Nitrous Oxide for Pain Management of Intrauterine Device (IUD) Insertion
The purpose of this study is to determine whether Nitrous Oxide is effective in achieving pain control and satisfaction among nulliparous women getting the intrauterine device (IUD).
- Trial name
- NIUD (NCT02391714)
- Testing
- IUD insertion, Povidone-Iodine, Chlorhexidine
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Pain Control With IUD Insertion
Pain Control for Intrauterine Device Placement: A Trial of Ketorolac Prior to Intrauterine Device Placement
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT01664559
- Testing
- Ketorolac, Normal Saline
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Lynn Ngo
Pain
Intracervical Lidocaine Gel for IUD Insertional Pain
The intrauterine device (IUD) is a form of birth control that is extremely effective and safe, even in women who have not yet had children.
- Trial name
- NCT01214161
- Testing
- 2% lidocaine gel
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Columbia University
IUD Insertion Pain, IUD Insertion
Intrauterine Device Insertion Pain Management
The goal of this clinical trial is to learn if use of topical benzocaine prior to the injection of lidocaine is effective in decreasing pain experienced during IUD insertion in patients 18 or older.
- Trial name
- NCT06951191
- Testing
- Benzocaine 20%, Lidocaine 2%, Saline 0.9%
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Pain
EMLA Cream as Analgesic for Outpatient Gynecological Procedures
The goal of this clinical trial is to compare pain perception in the study participant population undergoing the following gynecological procedures: Intra Uterine Device (IUD) insertion, hysteroscopy, and endometrial biopsy and…
- Trial name
- NCT05970354
- Testing
- EMLA Cream, VersaPro Cream Base for Compounding
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- CAMC Health System
IUD Insertion Pain
Oral Ketorolac for IUD Pain Reduction
To determine if oral ketorolac given at different timepoints prior to intrauterine device (IUD) insertion influences pain experienced during this procedure.
- Trial name
- NCT06853327
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
IUD, Endometrial Biopsy
2.5% Lidocaine/2.5% Prilocaine Cream for IUD Insertion and Endometrial Biopsy
The aim of this study is to determine if 5g of self-administered topical 2.5% lidocaine/2.5% prilocaine cream, reduces pain during IUD insertion and/or endometrial biopsy.
- Trial name
- NCT07768059
- Testing
- 2.5% lidocaine/2.5% prilocaine topical cream, VersaPro Cream Base for Compounding
- Where
- Canada
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
IUD Insertion Pain
Efficacy of Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Reduction During Intrauterine Device (IUD) Insertion in Outpatient Gynecology
Pain with intrauterine device (IUD) insertion is very common and there are few options for patients to help reduce this pain. Transcutaneous electric nerve stimulators (TENS) are a non-invasive procedure that may help reduce the…
- Trial name
- NCT06335823
- Testing
- Transcutaneous electrical nerve stimulation (TENS)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
IUD Insertion Complication, Acute Pain
LI4 Acupuncture for Analgesia in Intrauterine Device Insertion
Pain during IUD insertion is substantially psychologic in origin, responds extremely well to non-pharmacologic interventions. Considering the fact that acupuncture is a modality exerting both psychologic and physiologic effects…
- Trial name
- NCT04963582
- Testing
- Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Pain Control for Intrauterine Device Insertions
Paracervical Block Before Intrauterine Device (IUD) Insertion
The purpose of this study is to evaluate if a paracervical block containing 1% lidocaine administered prior to IUD insertion reduces insertion pain.
- Trial name
- NCT01207401
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Contraception, Intrauterine Device
10% Lidocaine Spray for Intrauterine Device Insertion
Intrauterine device (IUD) insertion is a procedure that can cause pain. Fear of pain during IUD insertion is a barrier to use of this method.
- Trial name
- LidocaineIUD (NCT03870711)
- Testing
- lidocaine spray
- Where
- Thailand
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Pain
Misoprostol Prior to Intrauterine Device (IUD) Insertion in Nulliparous Women
The purpose of this study is to see if using misoprostol makes the intrauterine device insertion easier and less painful in women who have never had a baby.
- Trial name
- NCT01307111
- Testing
- Misoprostol
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Contraception
Patient-Applied Pretreatment Analgesia for Intrauterine Device Placement
The goal of this clinical trial is to perform a pilot study looking at the benefit of topical anesthetic application to the cervix by tampon prior to intra-uterine device insertion.
- Trial name
- PAP-AID (NCT05890495)
- Testing
- Lidocaine topical, Tampon
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Pain
Photobiomodulation on Pain Perception During the Insertion of the T 380 Copper Intrauterine Device (IUD)
Unplanned pregnancy affects up to 65% of women in some regions of Brazil, contributing to unsafe abortions and maternal mortality.
- Trial name
- NCT06984796
- Testing
- Photobiomodulation, Simulation of Photobiomodulation
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Pain
Cervical Lidocaine for Intrauterine Device Insertion Pain
The aim of this study is to evaluate intracervical lidocaine gel as a means to decrease pain associated with intrauterine device (IUD) insertion.
- Trial name
- CLIIP (NCT01411995)
- Testing
- 2% lidocaine gel, Water based lubricant
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Pain
A Trial of 2% Lidocaine Gel for Intrauterine Device (IUD) Insertion
The intrauterine device (IUD) is a long-acting, highly effective, reversible contraceptive that may be underutilized due to fear of pain during insertion.
- Trial name
- NCT01292447
- Testing
- 2% lidocaine gel
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Pain Due to Intrauterine Contraceptive Device
Pain Control for Intrauterine Device Placement Using Paracervical Block
Intrauterine device (IUD) placement can be painful for patients during and after the procedure. Fear of pain from IUD insertion can be a barrier to obtaining this highly effective long acting reversible contraception.
- Trial name
- NCT02219308
- Testing
- Paracervical Block (PCB)
- Where
- 2 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Pain Associated With Intrauterine Device Insertion
LI4 Acupuncture for Pain During Intrauterine Device Insertion
This study will evaluate whether acupuncture can reduce pain during intrauterine device (IUD) insertion. Women undergoing IUD insertion will be randomly assigned to receive either real acupuncture at the LI4 point on both hands…
- Trial name
- NCT07854015
- Testing
- LI4 Acupuncture
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
IUD Insertion Complication
Lidocaine for Pain Control During Intrauterine Device Insertion
Despite being the most common method of contraception, the use of intrauterine devices (IUDs) is limited by the associated pain during insertion.
- Trial name
- NCT03362905
- Testing
- Lidocaine topical
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Ain Shams University