Clinical trials: Pain Intensity
Pain Relief, Analgesia
Benzocaine Versus Placebo Spray for Pain Relief at Hysterosalpingogram
The objective of this study is to assess the utility of benzocaine spray versus a placebo spray in alleviating pain during and after hysterosalpingogram (HSG).
- Trial name
- NCT01925469
- Testing
- Benzocaine, Saline spray
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Diabetic Neuropathic Pain
Genetics of Diabetes Audit and Research in Tayside Scotland (DOLORisk Dundee)
In 1997, the global prevalence of diabetes was estimated to be 125 million and this has risen to around 400 million in 2015. In addition diabetes has a number of complications including heart disease, blindness, kidney failure…
- Trial name
- GoDARTS (NCT02783469)
- Testing
- Identification of genetic causes of diabetic neuropathic pain
- Where
- United Kingdom
- Volunteers
- 1,915 people
- Sponsor
- University of Dundee
Endometriosis-related Pain
Randomized Trial Assessing Quinagolide Vaginal Ring for Endometriosis-related Pain
To evaluate the efficacy of three doses of quinagolide administered as an extended-release vaginal ring compared to placebo on reduction of moderate to severe endometriosis-related pain
- Trial name
- RAQUEL (NCT03692403)
- Testing
- Quinagolide 360 µg, Quinagolide 720 µg, Quinagolide 1080 µg
- Where
- 43 sites in United States
- Volunteers
- 22 people
- Sponsor
- Ferring Pharmaceuticals
Chronic Pain
An Interventional Study to Compare the Efficacy and Tolerability With Targin® in Non-malignant Chronic Pain (GLORY)
Objectives: 1. Objective of main interest To assess the drop-out rate caused by adverse event* after 6 weeks treatment 2. Further objectives To assess the drop-out rate caused by adverse event* after 1 week treatment To assess…
- Trial name
- NCT01811186
- Testing
- Oxycodone/naloxone
- Where
- South Korea
- Volunteers
- 261 people
- Sponsor
- Mundipharma Korea Ltd
Fear Pain
Human Behaviors Related to the Expectation of Pain
The conditioned expectation of pain is an important aspect of pain-related disability produced by environments and stimuli associated with a painful injury on the job, although the neuroscience of this expectation is unclear.
- Trial name
- NCT03739645
- Testing
- Skin conductance levels and slopes over time in conditioned fear as metrics.as metrics for anxiety
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Postoperative Pain
Hydromorphone and C-section
This study will investigate the dose of hydromorphone which will relieve the pain of women following a cesarean section when delivered directly in the area around the spinal cord (i.e., intrathecal injection).
- Trial name
- NCT01598545
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Fibromyalgia, Neck Pain
Kinesiophobia in Patients With Fibromyalgia Syndrome and Chronic Neck Pain
Kinesiophobia which is described as fear of movement reduces physical activity levels and increases the risk of chronic pain. The investigators consider that kinesiophobia levels are higher in patients with fibromyalgia syndrome…
- Conditions
- Fibromyalgia, Neck Pain, Healthy
- Trial name
- NCT03778801
- Testing
- kinesiophobia
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Aksaray University Training and Research Hospital
Chronic Pain
PainTracker Self-Manager: a Web-based Platform to Promote and Track Chronic Pain Self-management
To develop and test a web-based patient empowerment platform, PainTracker Self-Manager (PTSM), that can support integrated multimodal care in a variety of specialty and primary care settings.
- Trial name
- PTSM (NCT03045081)
- Testing
- PainTracker Self-Manager
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- University of Washington
Acute Pain
Tramadol Hydrochloride and Dexketoprofen Trometamol for the Oral Treatment of Moderate to Severe Acute Pain Following Removal of Impacted Lower Third Molar
The study is aimed to evaluate the analgesic efficacy of TRAM.HCl/DKP.TRIS 75mg/25mg oral fixed drug combination in comparison with TRAM.HCl /paracetamol 75mg/650mg in the treatment of moderate to severe acute pain.
- Trial name
- DAVID (NCT02777970)
- Testing
- Tramadol Hydrochloride/Dexketoprofen Trometamol, Tramadol Hydrochloride/Paracetamol
- Where
- 18 sites in Hungary, Italy and 3 more
- Volunteers
- 654 people
- Sponsor
- Menarini Group
Postoperative Pain, Obstetric Pain
Lidocaine Patches After Cesarean Section
The aim of this study is to investigate the impact of using lidocaine patches after cesarean section on pain control and opioid use in the immediate post-operative period.
- Conditions
- Postoperative Pain, Obstetric Pain, Opioid Use
- Trial name
- LPACS (NCT04443569)
- Testing
- Lidocaine patch
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Yale University
Coronary Artery Disease, Angina Pectoris
An Evaluation of Rigid Sternal Fixation in Supporting Bone Healing and Improving Postoperative Recovery
The primary objective of this study is to evaluate sternal bone healing following a full median sternotomy versus standard of care for sternal closure with wire cerclage.
- Conditions
- Coronary Artery Disease, Angina Pectoris, Cardiac Valve Disease
- Trial name
- SB (NCT01783483)
- Testing
- SternaLock Blue closure system, Suture Wire
- Where
- 12 sites in United States
- Volunteers
- 236 people
- Sponsor
- Zimmer Biomet
Acute Pain
Evaluation of Efficacy and Safety of VX-548 for Acute Pain After a Bunionectomy
The purpose of this study is to evaluate the efficacy and safety of suzetrigine for acute pain after a bunionectomy.
- Trial name
- NCT05553366
- Testing
- SUZ, HB/APAP
- Where
- 21 sites in United States
- Volunteers
- 1,075 people
- Sponsor
- Vertex Pharmaceuticals Incorporated
Neuropathic Pain
Study To Assess The Reproducibility And Sensitivity Of Quantitative Sensory Testing In Patients With Neuropathic Pain
Conventional pain efficacy measures such as Visual Analogue Scores (VAS) are often unable to detect treatment efficacy in small-scale clinical trials.
- Trial name
- NCT01117766
- Testing
- Pregabalin
- Where
- 5 sites in Austria, Belgium and 2 more
- Volunteers
- 31 people
- Sponsor
- Pfizer
Cervical Radiculopathy
Soft Tissue Mobilization Versus Therapeutic Ultrasound for Subjects With Neck and Arm Pain
The purpose of this study is to investigate effects of soft tissue mobilization versus therapeutic ultrasound in subjects with neck and arm pain who demonstrate neural mechanical sensitivity.
- Trial name
- NCT02081456
- Testing
- Soft Tissue Mobilization, Therapeutic Ultrasound
- Volunteers
- 23 people
- Sponsor
- Emilio J Puentedura, PT, DPT, PhD
Postoperative Pain
Transversus Abdominis Plane (TAP) Block Laparoscopic Hysterectomy
The transversus abdominis plane (TAP) block involves the sensory nerve supply of the anterior -lateral abdominal wall where the T7-12 intercostal nerves, ilioinguinal, iliohypogastric and the lateral cutaneous branches of the…
- Trial name
- TAP HYS (NCT01074229)
- Testing
- Drug .5% Ropivacaine, 20 cc of 0.25% ropivacaine
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Northwestern University
Neuropathy, Pain
Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer
This randomized phase III trial studies calcium and magnesium to see how well they work in preventing peripheral neuropathy caused by ixabepilone in patients with breast cancer.
- Conditions
- Neuropathy, Pain, Recurrent Breast Carcinoma, Stage IV Breast Cancer
- Trial name
- NCT00998738
- Testing
- Calcium Gluconate, Magnesium Sulfate, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Back Pain
The Effect of PTH(1-84) or Alendronate on Reduction of Back Pain in Postmenopausal Women With an Osteoporosis Related Vertebral Fracture(s) (FP-005-IM)
The primary objective of this trial is to show that PTH(1-84) is superior to alendronate in reducing back pain intensity over a 24-week treatment period in postmenopausal women with an osteoporosis related vertebral fracture(s).
- Trial name
- NCT00713258
- Testing
- Parathyroid hormone (PTH) (1-84), Alendronate
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Nycomed
Postoperative Pain
Prolonged Popliteal Fossa Nerve Blockade (Prolonged Pop)
This study looks at addition of medications to the local anesthetic for the nerve blockade.
- Trial name
- NCT02198235
- Testing
- Dexamethasone, Buprenorphine
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Hospital for Special Surgery, New York
Pain Due to Certain Specified Procedures
Pilot Study of Sucrose to Reduce Pain in Sick Babies
Small amounts of sweet tasting sugar water reduces pain in babies during painful blood tests and injections. The investigators do not know if sugar also reduces pain in babies already receiving a continuous infusion of opioid…
- Trial name
- NCT01438008
- Testing
- 24% sucrose po solution
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Eastern Ontario
Diabetic Peripheral Neuropathic Pain
DS-5565 Phase III Study for Diabetic Peripheral Neuropathic Pain
Investigate the efficacy and safety of DS-5565 in subjects with Diabetic Peripheral Neuropathic Pain (DPNP) in comparison to placebo
- Trial name
- NCT02318706
- Testing
- DS-5565
- Where
- Japan
- Volunteers
- 854 people
- Sponsor
- Daiichi Sankyo Co., Ltd.