Clinical trials: Pain Intensity Assessment
Herpes Zoster
A Study to Assess the Burden of Herpes Zoster and Postherpetic Neuralgia in Japanese Adults Aged Sixty Years and Above
The study aims to estimate the incidence of herpes zoster (HZ), proportion of postherpetic neuralgia (PHN) and the economic burden and impact on quality of life, in Japanese adults greater than or equal to sixty years of age.
- Trial name
- NCT01873365
- Testing
- Data collection
- Where
- 14 sites in Japan
- Volunteers
- 448 people
- Sponsor
- GlaxoSmithKline
Pain, Osteoarthritis, Hip
Placebo-controlled Trial With OROS Hydromorphone Hydrochloride to Treat Patients With Moderate to Severe Pain Induced by Osteoarthritis of the Hip or the Knee
This clinical trial tests the pain relieving effectiveness of OROS hydromorphone, a once-daily formulation of a strong opioid against placebo in patients, who are suffering from pain due to osteoarthritis of the hip or the knee…
- Conditions
- Pain, Osteoarthritis, Hip, Osteoarthritis, Knee
- Trial name
- NCT00980798
- Testing
- OROS hydromorphone HCl
- Where
- 12 sites in Czechia, Romania and 2 more
- Volunteers
- 288 people
- Sponsor
- Janssen-Cilag International NV
Anterior Cruciate Ligament Reconstruction
Iovera° to Treat Pain Associated With ACL Reconstruction and Rehabilitation
To evaluate the outcomes of patients undergoing iovera° treatment of the ISN and AFCN on postoperative knee pain and function following anterior cruciate ligament reconstruction
- Trial name
- NCT03688477
- Testing
- iovera°
- Where
- United States
- Sponsor
- Pacira Pharmaceuticals, Inc
Nausea Post Chemotherapy, Vomiting
Pharmacokinetic and Pharmacodynamic Evaluation of Formulations of Δ9-THC
Study based on the pharmacokinetic, pharmacodynamic, safety and stability evaluation of 3 standardized formulations of THC, to be used in healthy volunteers and post-chemotherapy patients as an adjuvant in the symptomatic…
- Conditions
- Nausea Post Chemotherapy, Vomiting, Cancer Pain, Cancer Related Pain
- Trial name
- NCT05272865
- Testing
- Pharmacokinetic and pharmacodynamic profile of THC oral formulations with Dronabinol as comparator
- Where
- Colombia
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- LaSanta S A S
Acute Appendicitis
Efficacy of Transversus Abdominis Plane Block in Alleviating Acute Appendicitis
This study aims to evaluate the efficacy of Transversus Abdominis Plane (TAP) block in preoperative pain management for patients diagnosed with acute appendicitis who are scheduled for emergency surgery in the emergency…
- Trial name
- NCT06808737
- Testing
- Transversus Abdominis Plane Blockage
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Ankara City Hospital Bilkent
Primary Dysmenorrhea
Evaluation of the Effect of a Structured Yoga Exercise in Young Women With Primary Dysmenorrhea
Abstract Primary dysmenorrhea is a common gynecological condition affecting women of reproductive age and negatively impacting quality of life.
- Trial name
- NCT07520136
- Testing
- Yoga Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ankara University
Cardiac Arrest, Post-Anoxic Coma
Evaluation of the "Pupillary Pain Index" in Neurological Prognosis After Cardiac Arrest
Two-thirds of patients admitted to the Intensive Care Unit after a cardiac arrest die in the context of treatment withdrawal after a multimodal evaluation that determines an unfavorable neurological outcome.
- Conditions
- Cardiac Arrest, Post-Anoxic Coma, Anoxic Brain Injury
- Trial name
- CAPPI (NCT04336930)
- Testing
- Pupillary pain index (PPI)
- Volunteers
- 60 people
- Sponsor
- Central Hospital, Nancy, France
Low Back Pain, Chronic Low-back Pain
Physical Exam, Static & Dynamic Ultrasound Assessment, & Treatment of Thoracolumbar Fascia (TLF) Mediated Low Back Pain
This Study is for our continued study of the Thoracolumbar Fascia (TFL) in patients with and without low back pain by our experienced multidisciplinary team: Vincent Wang PhD, VT Biomedical Engineering \& Mechanics (BEAM).
- Conditions
- Low Back Pain, Chronic Low-back Pain, Acute Low Back Pain
- Trial name
- NCT06818175
- Testing
- Ultrsound Guided Hydrodissection of the Thoracolumbar Fascia, Osteopathic Manipulative Treatment (OMT)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Low Back Pain, Type of Leg Pain (Radicular, Non-radicular)
The Course of Low Back Pain
This study aims to research the possible associations of education level, sedentary lifestyle, and type of low back pain (radicular vs non-radicular) with the course of low back pain and recovery rate.
- Conditions
- Low Back Pain, Type of Leg Pain (Radicular, Non-radicular), Lifestyle (Sedentary Behavior and Physical Activity), Start Back Screening Tool
- Trial name
- NCT04419675
- Testing
- Observational Cohort, usual care = physical therapy
- Where
- 6 sites in Netherlands
- Volunteers
- 347 people
- Sponsor
- Radboud University Medical Center
Rotator Cuff Injuries
Turkish Validity and Reliability of Short-Western Ontario Rotator Cuff Disability Index
The aim of this study is to adapt the Short-Western Ontario Rotator Cuff Disability Index (SHORTWORC) to Turkish society and to make its validity and reliability in Turkish.
- Trial name
- NCT06630039
- Testing
- Scale validity and reliability
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul Medeniyet University
Anesthesia, Cancer
Evaluation of Pain and Postoperative Nausea Vomiting Incidence in Outpatient Surgery at IUCT-Oncopole Hospital
The effectiveness of the analgesic and anti-nausea prevention techniques of the investigators justifies being evaluated regularly in order to adapt the management strategy to the specificities of each surgical act.
- Conditions
- Anesthesia, Cancer, Surgery
- Trial name
- NCT03669328
- Testing
- locoregional anesthesia
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Institut Claudius Regaud
Pulpitis - Irreversible, Resorption, Root
The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars
The aim of the study is to perform a clinical and radiographic evaluation of 70% Ethanol Alcohol versus Normal Saline as root canal irrigating solutions in partial pulpectomy of primary molars with Metapex.
- Conditions
- Pulpitis - Irreversible, Resorption, Root, Abscess Bone, Mobility, Tooth
- Trial name
- NCT04669392
- Testing
- 70% Ethanol Alcohol
- Volunteers
- 20 people
- Sponsor
- Cairo University
Neuropathic Pain
Spinal Cord Stimulation and Physiotherapy for Treatment of Neuropathic Pain
The study evaluates the combined effect of optimized pharmacological treatment, spinal cord stimulation and physiotherapy on pain relief, health-related quality of life and physical function in patients with neuropathic pain.
- Trial name
- SCS-PHYSIO (NCT03740763)
- Testing
- Spinal Cord Stimulation (SCS), Physiotherapy
- Where
- Sweden
- Volunteers
- 48 people
- Sponsor
- Göteborg University
Diabete Type 2
Normast3 for Adults With Diabetic Polyneuropathy
The goal of this clinical trial is to find out if a new supplement called Normast® 3 can help reduce nerve pain and improve nerve function in adults with diabetic polyneuropathy (DPN).
- Trial name
- NCT07689214
- Testing
- Normast® 3 - a food for special medical purposes (FSMP) containing co-micronized palmitoylethanolamide (PEA) with rutin and hydroxytyrosol. It is designed to support the management of diabetic polyneu
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Chest Pain, Gastroesophageal Reflux
Chest Pain Pilot Study
The purpose of this study is to compare the efficacy of Nexium® with placebo in relief of acid related pain or discomfort in the chest.
- Trial name
- NCT00251901
- Testing
- Esomeprazole
- Where
- 80 sites in Canada, Denmark and 4 more
- Volunteers
- 600 people
- Sponsor
- AstraZeneca
Pain, Postoperative, Opioid Use Disorder
Patient Engagement in Perioperative Pain Management Project
Previously, the study team evaluated the implementation and effectiveness of the Johns Hopkins Perioperative Pain Program (PPP), which coordinates continuum of care for surgical patients on chronic opioid therapy throughout the…
- Trial name
- NCT05252767
- Testing
- Patient Engagement Tools, Educational Guide
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- Johns Hopkins University
Spondylitis, Ankylosing
Extension in AS: Sustainability of Benefits, Safety and Tolerability
This 3-year extension study aims at making available the treatment with secukinumab in prefilled syringes (PFS) to patients with ankylosing spondylitis who took part in phase III study CAIN457F2305, defined as "core study", as…
- Trial name
- MEASURE 1 ext (NCT01863732)
- Testing
- Secukinumab
- Where
- 56 sites in United States, Belgium and 12 more
- Volunteers
- 274 people
- Sponsor
- Novartis Pharmaceuticals
Postherpetic Neuralgia
Efficacy and Safety of LX9211 in Participants With Postherpetic Neuralgia
Evaluation of the efficacy of LX9211 compared to placebo in reducing pain related to postherpetic neuralgia over an 11 week assessment period.
- Trial name
- RELIEF-PHN1 (NCT04662281)
- Testing
- LX9211
- Where
- 32 sites in United States, Czechia and 1 more
- Volunteers
- 79 people
- Sponsor
- Lexicon Pharmaceuticals
Interstitial Cystitis, Bladder Pain Syndrome
The CBD-IC Randomized Controlled Trial: Evaluation of Hemp Cannabidiol SuppositoRies for Pain and Urinary SymptOms in INterstitial Cystitis (CHRONIC)
This study seeks to exploit bladder cannabidiol receptors as a therapeutic drug target by conducting a double-masked, placebo-controlled randomized trial evaluating the effects of vaginal hemp cannabidiol (CBD) suppositories on…
- Trial name
- CHRONIC (NCT04349930)
- Testing
- Cannabidiol vaginal suppository
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
TMD
Masticatory Muscle Activity in Patients With Pain-related Temporomandibular Disorders
The aim of this study was to evaluate masticatory muscle electrical activity in patients with pain-related and pain-free temporomandibular disorders (TMD) as well as in subjects with no TMD.
- Trial name
- NCT04409067
- Testing
- electromyography
- Where
- Poland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin