Clinical trials: Pain Intervention
Postoperative Pain Management, Anxiety
The Effect of Preoperative Hugging With Family Members on Preoperative Anxiety Levels and Postoperative Pain
The aim of this randomized prospective study is to examine the effect of preoperative family hugging (for at least 20 seconds) on preoperative anxiety levels and postoperative pain.
- Conditions
- Postoperative Pain Management, Anxiety, Non-Pharmacological Interventions
- Trial name
- NCT07369544
- Testing
- Patients will be given the opportunity to hug family members for at least 20 seconds before the surgery., The standard anesthesia protocol will be followed
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Health Sciences Balikesir Hospital Eduation and Research
Injection Techniques, Nursing Interventions
Traction, Pressure, and Rapid Muscle Release (TPR) Technique During Intramuscular Injection: Effects on Pain and Patient Satisfaction
This study will be conducted to evaluate the effect of the Traction, Pressure, and Rapid Muscle Release (TPR) technique, an innovative method used during intramuscular vitamin B12 (cyanocobalamin) injections, on patients' pain…
- Conditions
- Injection Techniques, Nursing Interventions, Injection Pain Prevention, Patient Satisfaction
- Trial name
- TPRTDIMI (NCT07499687)
- Testing
- TPR Injection Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety
Effects of Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety for Patients Undergoing Elective Surgery
This study is a pilot randomized controlled trial (RCT) conducted at Tin Shui Wai Hospital to evaluate the effectiveness of a mobile-based mindfulness intervention in reducing preoperative anxiety among patients scheduled for…
- Conditions
- Mobile-based Mindfulness Intervention to Reduce Preoperative Anxiety, Pre-operative Anxiety, Postoperative Pain, Postoperative Use of Analgesics
- Trial name
- NCT07005973
- Testing
- mobile-based mindfulness intervention
- Where
- Hong Kong
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Hospital Authority, Hong Kong
Intervention Effectiveness
The Effect of Nada Yoga Music and Stress Ball Use on Anxiety and Pain Levels
This parallel-group randomized controlled trial was conducted between Aprıl 2025 and December 2025 at a Training and Research Hospital in Türkiye among women who applied for Pap smear testing.
- Trial name
- NCT07276607
- Testing
- Nada Yoga Music, Stress Ball group:, Nada Yoga Music + Stress Ball group
- Where
- Turkey (Türkiye)
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Agri Ibrahim Cecen University
Pain, Pain Intervention
Impact on Patients With Neuromuscular and Musculoskeletal Conditions Associated With Benign Chronic Pain Using Atlas Profilapxis
AtlasPROfilax®is a method performed in 2 authorized centers in Colombia focused on patients with chronic non-malignant pain. The study seeks to see the effectiveness of the method in different pathologies through a randomized…
- Trial name
- Atlasprofilax (NCT07745088)
- Testing
- Atlasprofilax Therapy
- Where
- Colombia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fundacion Nacional Somos
The Lumbar Spine Surgical Intervention, Arthrodesis
Evaluation of the Effect of Reiki on Pain After Lumbar Surgery
The goal of this clinical trial (prospective, comparative, and randomized double-blind study) is to learn if Reiki (a non-pharmacological intervention), when used alongside standard care, can treat and reduce postoperative pain…
- Conditions
- The Lumbar Spine Surgical Intervention, Arthrodesis, Severe Herniated Disc, Scoliosis
- Trial name
- REDAL (NCT07722117)
- Testing
- Reiki treatment and chirurgy
- Where
- 2 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Clinique Bizet
Emotion Management Skills, Lifestyle, Healthy
The Impact of Enhanced Music & Natural Visuals on Emotional Health
The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress.
- Conditions
- Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
- Trial name
- NCT07676110
- Testing
- soundBrilliance software application - Emotional Health
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- soundBrilliance LLC
Anxiety, Pain Management
Virtual Reality-Assisted Nursing Intervention During Intrauterine Device Insertion
Effect of Virtual Reality-Assisted Nursing Intervention on Pain and Anxiety During Intrauterine Device Insertion: A Randomized Controlled Trial April 30, 2026 The aim of this study was to evaluate the effect of a virtual…
- Conditions
- Anxiety, Pain Management, Virtual Reality, Nursing Interventions
- Trial name
- VR-IUD (NCT07580885)
- Testing
- via virtual reality goggles
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Mersin University
Non-Pharmacological Interventions, Breathing Exercise
Effect Of Game-Based Breathing Exercise On Pain, Fear, And Anxiety In Children During Venipuncture
Venipuncture is one of the most common invasive procedures in children and is often associated with significant pain, fear, and anxiety.This randomized controlled study will aim to evaluate the effects of a video game-based…
- Conditions
- Non-Pharmacological Interventions, Breathing Exercise, Venipuncture Pain, Pain Management
- Trial name
- NCT07550062
- Testing
- Intervention Group (Video Game-Based Breathing Exercise During Venipuncture), Video Game-Based Breathing Exercise Device
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University
Educational Intervention for Primary Care Professionals on Chronic Musculoskeletal Pain
PainTrain-AI Implementation Trial in Primary Care (Competency Gaps and Gender Bias)
Cluster trial to assess the effect of a digital clinical simulation (PainTrain AI) on clinical adequacy (0-100 rubric) across T0-T1-T2 in Primary Care.
- Trial name
- PT-AI-IMP (NCT07507019)
- Testing
- PainTrain-AI Educational Training, Usual Training / Standard Practice
- Where
- 2 sites in Spain
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Francesc Valenzuela Pascual
Massage Intervention
The Effect of Slow Stroke Back Massage on Pain and Fatigue in Women With Fibromyalgia
Fibromyalgia syndrome (FM) is defined as a non-inflammatory chronic pain syndrome with widespread pain in the musculoskeletal system, tender points (PINs) on physical examination and no specific laboratory findings.
- Trial name
- NCT06277375
- Testing
- Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Smoking Cessation Intervention, Pain
Oklahoma Study of Native American Pain Risk IV: Smoking Cessation and Pain
The goal of this pilot study is to assess whether 4-weeks of verified smoking abstinence following financial incentive treatment for smoking cessation improves physiological markers of chronic pain risk in adult Native American…
- Conditions
- Smoking Cessation Intervention, Pain, Smoking (Tobacco) Addiction
- Trial name
- OK-SNAPIV (NCT07080788)
- Testing
- Smoking Cessation
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Nursing Care, Pain
Effect of Music on Pain, Embarrassment, and Urodynamic Outcomes
Urodynamic testing (UDT) is a diagnostic procedure frequently used to evaluate lower urinary tract dysfunction, including urinary incontinence and voiding difficulties.
- Conditions
- Nursing Care, Pain, Music Intervention
- Trial name
- NCT07207746
- Testing
- Behavioral: Music Listening
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Pain, Pain Management
Replication Study: Reducing Pain With Focused Music Listening
The goal of this clinical trial is to confirm previous findings that actively tapping along to music can reduce pain more than just listening to music.
- Conditions
- Pain, Pain Management, Pain Threshold, Painful
- Trial name
- PainMusic2 (NCT06960226)
- Testing
- Music Listening, Silence Control, Active Sensorimotor Synchronization
- Where
- Norway
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Arm Pain, Arm Aesthetics
Cold Versus Warm Tumescent Solution in Arm Liposculpture
The goal of this clinical trial is to evaluate whether the temperature of tumescent solution (cold vs. warm) affects postoperative outcomes in adults undergoing arm liposculpture.
- Conditions
- Arm Pain, Arm Aesthetics, Liposuction, Safety of Intervention
- Trial name
- NCT06865911
- Testing
- Cold crystalloid infusions, 0.9%NaCl or Ringer's, Warm saline, Liposuction of the arms
- Where
- Colombia
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Eternal Beauty SAS
Intervention, Cervical
Cervical Epidural Versus Cevical Facet Injection for Patients With Chronic Cervical Pain
After approval of the institutional review board and the Ethics Committee of Al Fayoum University number (D228) , and written informed consent from all patientṣ Pilot study will be done to confirm this sample size .The patients…
- Conditions
- Intervention, Cervical, Epidural, Injection
- Trial name
- D228 (NCT04594876)
- Testing
- Flouroscopic guidance cervical epidural versus cervical facet injection
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Fayoum University Hospital
Music Intervention, Gingival Graft
Effect of a Personalized Sound Intervention During Autogenous Gingival Grafts in Adults
Anxiety feeds the avoidance of dental treatments, leading to the neglect of general oral health. This avoidance is often amplified by the fear of potential pain and dissatisfaction after a dental appointment.
- Conditions
- Music Intervention, Gingival Graft, Anxiety, Pain
- Trial name
- NCT05632679
- Testing
- personalized music intervention, selected audio book
- Where
- 3 sites in Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Université de Montréal
Interventions Pain
The Effects on Pain of Acupressure and Foot Reflexology Before Heel Lancing in Newborns
This study aimed to determine the effects of foot reflexology and acupressure on the KI3 and St36 points on pain during interventions when these procedures were administered before heel lancing in term newborns.
- Trial name
- NCT04643730
- Testing
- Acupressure methods, Foot Reflexology Methods, Control Grup
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Percutaneous Coronary Intervention
Effect of Ice Bag Application to Femoral Region on Pain in Patients Undergoing Percutaneous Coronary Intervention
Background: Removal of femoral arterial catheter causes pain, and current interventions used for reducing this pain are not sufficiently effective.
- Trial name
- NCT03131271
- Testing
- cold application
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Pain Detection, Pain Intervention
Pain Detection and Interception in Neonates
Hypothesis: 1. May the introduction of NIDCAP during blood sample reduced pain in neonates during blood sample 2. Compare the effect of venous and capillary blood sample method
- Trial name
- NCT00447824
- Testing
- Introduction of better conditions during blood sampling
- Where
- Norway
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF