Clinical trials: Pain Management Improvement
Stroke, Shoulder Pain
Hemiplegic Shoulder Pain Management Using Shoulder pRF and Corticosteroid Injection
Introduction: hemiplegic shoulder pain (HSP) in a common post-stroke condition, that can lead to poor motor and functional recovery and lower quality of life.
- Trial name
- NCT05563571
- Testing
- Methylprednisolon, Lidocaine, Pulsed radiofrequency, Lidocaine
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- Satasairaala
Pain Management, Critical Care
Evaluation of the Effectiveness of an Audit and Feedback Intervention With Quality Improvement Toolbox in Intensive Care
This study evaluates the addition of a quality improvement toolbox to an online audit and feedback intervention in Dutch intensive care units.
- Conditions
- Pain Management, Critical Care, Quality Improvement
- Trial name
- NCT02922101
- Testing
- Audit and Feedback, Toolbox
- Where
- Netherlands
- Volunteers
- 21 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Non-specific Low Back Pain (NSLBP)
Web-Based Exercise Program for Non-Specific Low Back Pain
This study evaluates the effectiveness of a web application-based exercise program (delivered via Physitrack) for managing non-specific low back pain (NSLBP) compared to traditional home exercise programs.
- Trial name
- WEBEX-LBP (NCT07208435)
- Testing
- Web-Based Therapeutic Exercise Program, Traditional Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Medipol University
Acute Post Operative Pain
Improvement in Postoperative Pain Outcomes
This is an observational study project aims at improving postoperative pain outcomes by evaluating the current status of postoperative pain managements in the institution.
- Trial name
- NCT05624502
- Where
- Saudi Arabia
- Volunteers
- 1,000 people
- Sponsor
- King Saud University
Pain, Postoperative
Nefopam for Post Video-Assisted Thoracoscopic Lobectomy
Video-assisted thoracoscopic (VATs) lobectomy is mild to moderately pain procedure. For conventional thoracotomy, there are many invasive pain control such as epidural analgesia, paravertebral block.
- Trial name
- NCT04241640
- Testing
- Nefopam 20 MG/ML
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Idiopathic Scoliosis, Post-operative Pain
Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis
This study hypothesizes that the addition of a low-dose ketamine infusion to usual post-operative pain management will improve pain control as evidenced by an improvement in post-operative pain scores for patients undergoing…
- Trial name
- NCT02651324
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Albany Medical College
Pain, Chronic, Opioid Use Disorder
Pain and Opioid Management in Older Adults
The extent and depth of the ongoing opioid crisis are well known and many interventions are under way in the United States and other countries to alleviate its devastating impact on individuals and the society.
- Trial name
- RISE-OK (NCT05037682)
- Testing
- Dissemination and Implementation Research
- Where
- United States
- Volunteers
- 1,035 people
- Sponsor
- University of Oklahoma
Malignant Female Reproductive System Neoplasm
Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies
This phase IV trial studies how well liposomal bupivacaine with or without hydromorphone works in improving pain control during the first 24 hours after surgery in patients with gynecological malignancies undergoing laparotomy.
- Trial name
- NCT04258631
- Testing
- Hydromorphone, Laparotomy, Liposomal Bupivacaine
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Mayo Clinic
Arthroscopic Surgery
Effectiveness of Per-Operative Bupivicaine in Reducing Postoperative Pain at Port Site and Improving Mobility in Knee Arthoscopic Procedures
The investigator's aim is to evaluate the effectiveness of per-operative bupivacaine infiltration at arthroscopic port sites in reducing post-operative pain compared to placebo in patients undergoing knee arthroscopic procedures.
- Trial name
- NCT07090928
- Testing
- 5 ml of 0.5% bupivacaine infiltrated at each port site
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Khyber Teaching Hospital
Pancreatic Cancer
Endoscopic Radiofrequency Ablation of Celiac Ganglion for Pain Management and Improvement of Quality of Life in Patients With Unresectable Pancreatic Cancer
This study aims to evaluate the EUS-RFA in terms of efficacy for pain management and improvement in quality-of-life parameters for patients with advanced inoperable pancreatic cancer.
- Trial name
- NCT05535894
- Testing
- Ablation of Celiac Ganglion
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- West Virginia University
Chronic Pain
Intrathecal Morphine Compared to Conventional Medical Management for Pain Control and Opioid-related Side Effects
This study compares two different ways to treat pain. The two ways are: 1. continuing to take current pain medication(s) or 2. receiving morphine, a pain medication from a drug pump (a system to deliver drug to your body) that is…
- Trial name
- CONVERT-TDD (NCT01924182)
- Testing
- SynchroMed Infusion System and Intrathecal Morphine Sulfate, Conventional Medicine
- Where
- 6 sites in United States
- Volunteers
- 7 people
- Sponsor
- MedtronicNeuro
Burn
Study in the Use of Virtual Reality as an Adjunct to Pain Control in Burn Patients
The purpose of this study is to evaluate the use of Virtual Reality (VR) technology during Physical Therapy (PT) and/or Occupational Therapy (OT) for patients with burns.
- Trial name
- NCT00591448
- Testing
- Virtual Reality (VR)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Alcoholic Patient, Carcinological Surgery ORL
Systemic Ketamine for the Improvement of Post-Operative Analgesia at the Alcohol-Dependent Patient
The principal objective is to evaluate the analgesic effectiveness of the systemic ketamine on the control of the pain (average consumption of morphine at 48 hours) at the alcool-dependent patient, in carcinological surgery ORL.
- Trial name
- NCT00329394
- Testing
- ketamine
- Where
- France
- Volunteers
- 56 people
- Sponsor
- University Hospital, Clermont-Ferrand
Gender Dysphoria
Development of Effective, Opioid Sparing Techniques for Peri-operative Pain Management of Transgender Patients Undergoing Gender Affirming Surgeries
This study will compare the current standard-of-care pain treatment regimen options that are available to patients who undergo gender-affirming surgery.
- Trial name
- NCT04979338
- Testing
- Ultrasound guided Continuous Infraclavicular Brachial Plexus Block, Ultrasound guided Continuous Femoral Nerve Block, Ultrasound guided Pudendal Nerve Block
- Where
- United States
- Volunteers
- 640 people
- Sponsor
- Cedars-Sinai Medical Center
Chronic Pain
The Application of Performance Improvement Principles to the Patient Throughput Process in an Adult Outpatient Pain Treatment Clinic
This study is undertaken to assess and improve the existing patient flow, or so-called throughput process, in an adult outpatient pain treatment clinic.
- Trial name
- NCT00888420
- Testing
- Performance Improvement Measures
- Where
- United States
- Volunteers
- 1,221 people
- Sponsor
- University of Alabama at Birmingham
Spinal Cord Injuries (SCI), Paralysis, Lower Limbs
Epidural Electrical Stimulation to Restore Standing and Walking in Patients With Chronic Paralysis Due to Spinal Cord Injury: A Study on Motor Recovery, Spasticity Reduction, and Quality of Life Improvement Through Neuromodulation and Intensive Rehabilitation
Spinal cord injury (SCI) is a major cause of morbidity and disability worldwide, significantly impacting patients' quality of life and functional independence.
- Trial name
- EPISTIM-SCI (NCT06847295)
- Testing
- Epidural Electrical Stimulation (EES) using an implanted paddle lead and pulse generator combined with a 12-month intensive rehabilitation program.
- Where
- Brazil
- Volunteers
- 10 people
- Sponsor
- University of Sao Paulo General Hospital
Cancer
Improving Pain Management in Hospitalized Cancer Patients. A Before-after Cluster Phase II Trial
The objective of the study is to evaluate the efficacy of the Pac-IFicO programme in improving the quality of pain management in hospitalised cancer patients.
- Trial name
- NCT02035098
- Testing
- the Pac-IFicO programme
- Volunteers
- 504 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Pain, Cancer
Improvement of Self Management for Oncologic Patients With Pain
This study will test the SCION (Self care improvement through oncology nursing)-PAIN program, a multi-modular structured intervention to improve self management in oncologic patients with pain compared to care as usual (standard…
- Trial name
- NCT00779597
- Testing
- SCION (Self care improvement through oncology nursing)-PAIN program
- Where
- 3 sites in Germany
- Volunteers
- 208 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Chronic Pain
Veterans' Pain Care Organizational Improvement Comparative Effectiveness Study
Background and significance: Treatment with opioid pain medications (like hydrocodone and morphine) is common for severe pain, but studies show these medications may not always help and can cause serious problems.
- Trial name
- VOICE (NCT03026790)
- Testing
- Medication management, Non-pharmacological pain management, Buprenorphine-Naloxone
- Where
- United States
- Volunteers
- 820 people
- Sponsor
- University of Minnesota
Postoperative Analgesia
Magnesium and Ketamine in Postoperative Analgesia
90 female patients scheduled for cancer breast surgeries will be assigned to 2 groups, each of 45. Group (K) will receive a bolus of 0.5 mg/kg ketamine with induction of anaesthesia, followed by ketamine infusion 0.12 mg/kg/hour…
- Trial name
- NCT04111848
- Testing
- Ketamine, ketamine and magnesium
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- National Cancer Institute, Egypt