Clinical trials: Pain Management and Care
Pain, Chronic, Opioid Use Disorder
Pain and Opioid Management in Older Adults
The extent and depth of the ongoing opioid crisis are well known and many interventions are under way in the United States and other countries to alleviate its devastating impact on individuals and the society.
- Trial name
- RISE-OK (NCT05037682)
- Testing
- Dissemination and Implementation Research
- Where
- United States
- Volunteers
- 1,035 people
- Sponsor
- University of Oklahoma
Stress Related Disorder, Pain
Analgesia Nociception Index for Pain Monitoring in Intensive Care Units
The aim of this study is to examine the usability of ANI in patients who will be treated in intensive care unit.
- Conditions
- Stress Related Disorder, Pain, Intensive Care Unit Syndrome
- Trial name
- NCT05313789
- Testing
- Analgesia Nociception Index (ANI)
- Volunteers
- 180 people
- Sponsor
- İstanbul Yeni Yüzyıl Üniversitesi
FISTULA IN ANO
Comparison Between Laser and Open Fistula Surgeries in the Management of Fistula - In - Ano
This prospective randomized controlled trial compared the outcomes of laser versus open surgical techniques in the management of fistula-in-ano among 100 patients at a tertiary care center.
- Trial name
- NCT07083778
- Testing
- Laser Fistula Surgery (FiLaC - Fistula-tract Laser Closure), Open Fistula Surgery (Fistulotomy, Fistulectomy, or LIFT Procedure)
- Where
- India
- Volunteers
- 100 people
- Sponsor
- GSVM Medical College
Critical Illness, Post Intensive Care Unit Syndrome
pEEG Monitoring Effect on Delirium, Ventilator Days, and PICS
The goal of this multi-site observational study is to compare delirium rates, days on mechanical ventilation, and Post Intensive Care Syndrome (PICS) rates in adult Intensive Care Unit (ICU) patients.
- Conditions
- Critical Illness, Post Intensive Care Unit Syndrome, Post Intensive Care Syndrome, Mechanical Ventilation Complication
- Trial name
- NCT06019078
- Testing
- SedLine
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Fraser Health
Pain, Chronic Disease
Improving Chronic Pain Treatment in Primary Care
The primary objective of this study is to determine to what extent a collaborative intervention improves chronic pain-related outcomes in a VA primary care setting.
- Conditions
- Pain, Chronic Disease, Depression
- Trial name
- SEACAP (NCT00129480)
- Testing
- Assistance with Pain treatment
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- VA Office of Research and Development
Chronic Pain
Group-based Integrative Pain Management in Primary Care Safety Net Clinics
Socioeconomically disadvantaged populations have a high prevalence of chronic pain, exacerbated by social isolation, intersectional stigma, and disparities in pain assessment and treatment options.
- Trial name
- IPMP+ (NCT06327542)
- Testing
- Group Acupuncture, Integrative Group Medical Visits
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- University of California, San Francisco
Laparoscopic Cholecystectomy
ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
This clinical study aims to evaluate the effects of multimodal analgesia management administered within an ERAS (Enhanced Recovery After Surgery) protocol on postoperative pain, length of hospital stay, early complications, and…
- Trial name
- ERAS (NCT06885086)
- Testing
- Control group - 1, Observation group -2
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postoperative Pain, Anesthesia, Local
Additional Effect of Wound Infiltration After Cesarean Section With Optimal Standard Analgesia
The purpose of this study is to determine wether wound infiltration brings additional analgesia effect after cesarean section with optimal standard postoperative analgesia
- Conditions
- Postoperative Pain, Anesthesia, Local, Breast Feeding
- Trial name
- KTcesar (NCT01751256)
- Testing
- Continuous wound infiltration
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Poissy-Saint Germain Hospital
Subacute Nonspecific Low Back Pain, Chronic Nonspecific Low Back Pain
Effectiveness of Group GDS and Individual GDS for Treatment of Low Back Pain in Primary Care
A cluster, randomized, controlled clinical trial, where the hypothesis is that Group GDS and Individual GDS are effective in the treatment of nonspecific low back pain.
- Trial name
- NCT01060280
- Testing
- Education on active management, Group GDS physiotherapy, Individual GDS physiotherapy
- Where
- Spain
- Volunteers
- 461 people
- Sponsor
- Kovacs Foundation
Post Operative Pain, Osteoarthritis, Knee
ZYNRELEF for Pain Management in Total Knee Arthroplasty
The goal of this randomized controlled trial is to compare opioid medication consumption after surgery for patients who have a total knee replacement.
- Trial name
- NCT05644496
- Testing
- Bupivacaine-Meloxicam 400 Mg-12 Mg/14 mL Injectable Solution, Extended Release
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Baptist Health South Florida
Spinal Fusion, Hyperglycemia
Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery
This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes…
- Conditions
- Spinal Fusion, Hyperglycemia, Postoperative Pain Management, Postoperative Care
- Trial name
- TAPIS (NCT07218133)
- Testing
- Auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Alexander T. Yahanda
Burn
Virtual Reality Pain Control During Burn Wound Care
Using Virtual Reality as a form of Distraction during Burn Care.
- Trial name
- VRPT/H2O/RT (NCT00261690)
- Testing
- Virtual Reality Distraction
- Where
- United States
- Volunteers
- 184 people
- Sponsor
- National Institute of General Medical Sciences (NIGMS)
Hemorrhoid, Anal Fistulas
Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery
The study, "Effect of Listening to Standardized Music Sequences on Preventing Postoperative Pain in Proctologic Surgery," aims to evaluate the impact of preoperative listening to standardized music sequences on postoperative pain…
- Conditions
- Hemorrhoid, Anal Fistulas, MUSICAL THERAPY, Anal Fissure and Fistula
- Trial name
- MUSICOPROCTO (NCT06798155)
- Testing
- Standardized Music Listening Therapy
- Where
- 2 sites in Reunion
- Volunteers
- 550 people
- Sponsor
- Clinique Saint-Vincent
Pain
Reduction of Pain in Childhood Vaccination in the Primary Care Nurse Vaccination Consultation
Non-randomized study with control group (CG) with the objective of analyzing the non-pharmacological analgesic efficacy of the "Painless Vaccine" protocol for the reduction of pain during vaccination in the population aged 2…
- Trial name
- NoVacPain (NCT06004258)
- Testing
- Painless Vaccination
- Where
- Spain
- Volunteers
- 495 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario Virgen Macarena
Persistent Pain, Pain Management
Self-monitoring and Remote Monitoring of Chronic Pain in Primary Care - Using a Digital Tool to Improve Quality of Life
Chronic pain impacts individuals, their families, and society significantly, yet specialist care resources are limited, with most patients managed in primary care.
- Conditions
- Persistent Pain, Pain Management, Remote Monitoring
- Trial name
- NCT07141108
- Testing
- Paindrainer Care system
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Lund University
Persistent Post-surgical Pain, Neuropathic Pain
Development of a Personalised Care Plan Designed to Reduce Chronic Post-Operative Pain Following Breast Surgery
Numerous surveys have shown that following breast surgery, longterm pain affects around half of patients. Given that 1 in 9 women will get breast cancer and that surgery is the cornerstone of treatment, persistent pain represents…
- Conditions
- Persistent Post-surgical Pain, Neuropathic Pain, Cancer Pain
- Trial name
- NCT02170415
- Testing
- Protective analgesia, Pain education, Psychological support
- Where
- United Kingdom
- Volunteers
- 154 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Post-craniotomy Pain Management, Post-craniotomy
Comparison of Pain Using CPOT Score With Ketamine vs. Dexmedetomidine in Post-Craniotomy ICU Patients
Study Overview: This study is designed to compare two different medications used to manage pain after craniotomy surgery in the ICU.
- Conditions
- Post-craniotomy Pain Management, Post-craniotomy, Pain Control in ICU, Ketamine vs Dexmedetomidine for Pain Relief
- Trial name
- CPOT-KD (NCT07254936)
- Testing
- ketamine, Dexmedetomidine
- Where
- Indonesia
- Volunteers
- 38 people
- Sponsor
- Universitas Sumatera Utara
Chronic Neck Pain
Diaphragmatic Breathing and Electroacupuncture for Chronic Neck Pain
Chronic non specific neck pain is a prevalent musculoskeletal disorder with significant impact on pain, forward head posture, and neck disability.
- Trial name
- NCT07684092
- Testing
- physiotherapy care, diaphragmatic breathing, and electroacupuncture, physiotherapy care, simple focused breathing exercises, and electroacupuncture
- Where
- Pakistan
- Volunteers
- 72 people
- Sponsor
- University of Lahore
Cesarean Section, Cesarean Delivery
Pain Management After Cesarean Section - A Before-and-After Cohort Study
Inadequate pain relief remains a challenge after Cesarean section (CS) and may significantly impair postoperative recovery. A recent Danish single-center study (n=100) revealed that 66% of elective CS patients experienced severe…
- Conditions
- Cesarean Section, Cesarean Delivery, Pain Management, Pain Management in Postoperative Care
- Trial name
- NCT06813638
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Nordsjaellands Hospital
Cancer, Heart Failure
Virtual Reality as an Adjunct to Management of Pain and Anxiety in Palliative Care
Virtual reality has been shown to be an effective way to treat pain and anxiety in various different settings. Palliative care is an area of medicine that often deals with patients suffering from pain and anxiety.
- Conditions
- Cancer, Heart Failure, Copd, ALS
- Trial name
- NCT04138095
- Testing
- Virtual Reality
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Riverview Health Centre