Clinical trials: Pain Palliation
Bone Metastases
Effectiveness and Safety of ArcBlate Palliative Treatment for Patients With Painful Bone Metastases: A Pivotal Study
A Pivotal Study to Evaluate the Effectiveness and Safety of ArcBlate Palliative Treatment for Patients With Painful Bone Metastases
- Trial name
- NCT06487013
- Testing
- ArcBlate Focused Ultrasound Ablation System
- Where
- 4 sites in Taiwan
- Volunteers
- 100 people
- Sponsor
- EpiSonica
Neurological Impairment
Music Therapy for Pain Modification in Pediatric Palliative Care
The purpose of this within-subjects randomized controlled trial is to determine whether two music therapy interventions are efficacious in reducing pain symptoms, in order to improve the quality of care for children in pediatric…
- Trial name
- NCT01456884
- Testing
- Live guitar and vocal music therapy, Vibroacoustic Music Therapy
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- University of British Columbia
Pain, Phlebotomy
Synera Venipuncture Pain
Synera, which is a heated topical patch containing both lidocaine and tetracaine, is intended to reduce the pain associated with venipuncture and superficial dermatologic procedures by numbing the skin.
- Conditions
- Pain, Phlebotomy, Palliative Care
- Trial name
- NCT01744197
- Testing
- Synera (lidocaine 70mg/tetracaine 70mg)
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- US Oncology Research
Cancer Pain, Refractory Pain
Radiosurgery for Severe Refractory Cancer Pain: A Sham-Controlled Pilot Trial
This pilot randomized trial assessed whether a sham-controlled comparison of triple-target stereotactic radiosurgery is feasible in adults with advanced (stage IV) cancer and severe mixed pain refractory to optimized…
- Trial name
- NCT07871123
- Testing
- Triple-target stereotactic radiosurgery
- Where
- El Salvador
- Volunteers
- 10 people
- Sponsor
- Centro Internacional del Cáncer
Traumatic Brain Injury, Post-traumatic Stress Disorder
Improving Sleep in Veterans With the Polytrauma Clinical Triad
The "polytrauma clinical triad" (PCT), a highly disabling constellation of factors, is defined by the coexistence of traumatic brain injury, post-traumatic stress disorder, and chronic pain.
- Conditions
- Traumatic Brain Injury, Post-traumatic Stress Disorder, Chronic Pain
- Trial name
- LIONv2 (NCT06477796)
- Testing
- Morning Bright Light Therapy, Negative Ion Generator
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- VA Office of Research and Development
Cancer, Cancer Pain
Effect of Music on Pain and Anxiety in Palliative Cancer Patients
Background: Cancer patients receiving palliative care often endure a variety of distressing symptoms, most notably pain and anxiety.
- Conditions
- Cancer, Cancer Pain, Palliative Care, Anxiety
- Trial name
- NCT07262151
- Testing
- Music Application, Procedures for the Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Karamanoğlu Mehmetbey University
Bone Lesion, Bone Metastases
Ablation and Cementoplasty for Painful Bone Lesions
The aim of this research study is to assess the effectiveness of combined ablation and cementoplasty in the treatment of spinal, pelvic, and extraspinal lesions causing pain resistant to conventional treatment at our centre.
- Conditions
- Bone Lesion, Bone Metastases, Spine Metastases
- Trial name
- NCT04635137
- Testing
- Ablation and Cementoplasty
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Calgary
Gastric Cancer
Palliative Radiotherapy for Symptomatic Locally Advanced Gastric Cancer: A Phase II Trial
The hypothesis of this study is that a radiotherapy dose of 36Gy in 12 fractions, which equates to a BED of 48.6Gy, increases the response rates of symptom relief compared to historical controls.
- Trial name
- NCT01341756
- Testing
- Palliative Radiotherapy
- Where
- Singapore
- Volunteers
- 63 people
- Sponsor
- National University Hospital, Singapore
Myofascial Pain Syndromes, Cancer
Efficacy of Myofascial Pain Syndrome Treatment in Patients With Cancer in Palliative Care
Palliative Care is active holistic care offered to people who are in intense suffering related to their health, resulting from a serious life-threatening illness, with a focus on improving the quality of life.
- Trial name
- NCT04703803
- Testing
- 1% lidocaine injection in trigger points
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Renal Cell Carcinoma
Study of Sorafenib and Palliative Radiotherapy in Kidney Cancer That Spreads to the Bone
The purpose of this study is to investigate the use of a new anti-angiogenic drug called sorafenib, in combination with radiotherapy, for renal cell cancer that has spread to the bone and is causing significant pain.
- Trial name
- NCT00609934
- Testing
- Sorafenib, external beam radiotherapy
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University Health Network, Toronto
Chronic Low-back Pain, Nociceptive Pain
PET/CT Guided Robotic Arm-assisted Pain Palliation in Chronic Nociceptive Low Backache
A study to investigate the role of F-18 sodium fluoride in localizing the pain generator in participants with chronic nociceptive musculoskeletal low back ache and to study the use of PET/CT guided robotic arm assisted injection…
- Trial name
- NCT05560165
- Testing
- F-18 sodium fluoride PET/CT guided robotic arm assisted injection of combination of local anesthetic and steroids
- Where
- India
- Volunteers
- 85 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hypnosis, Perioperative Care
Hypnosis for Symptom Management in Elective Orthopedic Surgery
The purpose of the study is to determine if teaching self-hypnosis techniques to patients prior to knee replacement surgery will decrease their pain medication requirements, pain medication side-effects, length of stay in the…
- Conditions
- Hypnosis, Perioperative Care, Knee Arthroplasty, Total, Postoperative Pain
- Trial name
- NCT03308071
- Testing
- Hypnosis
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Stanford University
Malignancy-induced Pelvic Pain
CT-guided Pudendal Nerve Cryoneurolysis for Palliation of Malignancy-induced Pelvic Pain
We want to study if a new treatment called "CT-guided bilateral pudendal nerve cryoneurolysis" can help people with severe and long-lasting pain in the pelvic area caused by cancer.
- Trial name
- NCT06110065
- Testing
- CT-guided Pudendal Nerve Cryoneurolysis, Percutaneous image-guided cryoneurolysis
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Arizona
End-Stage Renal Disease Requiring Haemodialysis, Mobile Application
Evaluation of the Effectiveness of a Mobile Application Developed for Hemodialysis Patients.
This study aims to evaluate the effectiveness of a mobile health application developed for adult patients undergoing hemodialysis treatment.
- Trial name
- NCT07211100
- Testing
- Mobile Health Application
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Saglik Bilimleri Universitesi
Pain, Pancreatic Cancer
Safety and Efficacy of Cryoablation for Abdominal Pain Associated With Pancreatic Cancer
CUC10-PAN09 will evaluate the safety and efficacy of cryoablation therapy on the relief of epigastric/abdominal pain associated with pancreatic cancer.
- Trial name
- NCT01335945
- Testing
- Cryoablation
- Where
- 3 sites in United States
- Volunteers
- 14 people
- Sponsor
- Boston Scientific Corporation
Tracheostomy, Care
The Effects of Listening to Fairy Tales, Listening to Fairy Tales in Their Mothers' Voices, and Watching Cartoons on Pain, Comfort Levels, and Physiological Parameters During Tracheostomy Care in a Palliative Care Clinic
This study aimed to determine the effects of listening to fairy tales, listening to fairy tales from the mother's voice, and watching cartoons on pain, comfort, and physiological parameters during tracheostomy care of children…
- Trial name
- NCT07210346
- Testing
- fairy tales, mother's voice, Cartoons
- Where
- Turkey (Türkiye)
- Volunteers
- 17 people
- Sponsor
- Ataturk University
Unconscious State, Pressure Ulcer
Nociception Monitoring in Intensive Care
Precisely, pain in the ICU is a multidimensional problem with a multivariate of reasons. Still, it would be simpler to manage it in unconscious palliative patients with less source of pain, but only if we can detect it…
- Trial name
- NCT06270264
- Testing
- the Nociception level index monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Haseki Training and Research Hospital
HIV Infections, Cancer
A Multicenter Phase II/III, Placebo-Controlled Study of SNX-111 Administered Intrathecally to Cancer and AIDS Patients With Chronic Pain
To determine the safety and efficacy of SNX-111 in controlling severe, chronic pain in cancer and AIDS patients.
- Conditions
- HIV Infections, Cancer, Pain
- Trial name
- NCT00002160
- Testing
- Ziconotide
- Where
- 44 sites in United States
- Volunteers
- 100 people
- Sponsor
- Neurex
Bone Metastases, Bone Neoplasm
Focused Ultrasound and RadioTHERapy for Noninvasive Palliative Pain Treatment in Patients With Bone Metastases
The FURTHER study aims to evaluate the effectiveness and cost-effectiveness of MR-HIFU (alone or in combination with EBRT) compared to EBRT alone, the standard-of-care, as a palliative treatment option to relieve CIBP.
- Conditions
- Bone Metastases, Bone Neoplasm, Bone Lesion, Bone Cancer
- Trial name
- FURTHER (NCT04307914)
- Testing
- External beam radiotherapy, MR-HIFU
- Where
- 6 sites in Finland, Germany and 2 more
- Volunteers
- 216 people
- Sponsor
- UMC Utrecht
Cancer, Terminal Disease
Occupational Therapy Modulates the Pain in Cancer Patient Under Palliative Care
Pain is one of the most incapacitating symptoms because it is a complex experience that includes sensory and emotional perceptions, in which sensory, affective, cognitive, behavioral, cultural and social characteristics interact.
- Conditions
- Cancer, Terminal Disease, Pain
- Trial name
- NCT02102178
- Testing
- Tapestry, Regular occupation therapy, Weaving a scarf on a nail frame
- Volunteers
- 58 people
- Sponsor
- Barretos Cancer Hospital