Clinical trials: Pain Reduction
Pain
Does Montelukast Decrease Post Adenotonsillectomy Pain in Children
Objective: The purpose of the present study is to evaluate the effectiveness of preoperative Montelukast as an analgesic for adenotonsillectomy Study Design: Randomized controlled double blinded clinical trial.
- Trial name
- Montelukast (NCT02793375)
- Testing
- Montelukast
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Procedural Anxiety, Procedural Pain
Stress Ball and Empathic Verbal-Tactile Interventions for Reducing Anxiety and Pain in Mammography and Breast Ultrasonography: A Randomized Trial
This prospective, randomized controlled trial aims to determine the effects of stress ball use and empathic verbal communication with therapeutic touch on anxiety and pain perception in women undergoing mammography and breast…
- Conditions
- Procedural Anxiety, Procedural Pain, Breast Imaging
- Trial name
- NCT07562828
- Testing
- Stress Ball, Empathic Verbal-Tactile Intervention
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Intramuscular Injection, Pain
The Effect of Helfer Skin Tap Technique During Tetanus Injection in Pregnant Women
Intramuscular (IM) vaccination administered using the right injection technique is known to cause less pain and injury. Nurses employ different approaches like applying pressure, tapping the skin, cold and hot applications for…
- Trial name
- NCT05761340
- Testing
- Helfer skin tap injection technique, Standard Injection technique
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Manisa Celal Bayar University
Inflammation, Pain
Efficacy of Tart Cherry Juice in Reducing Muscle Injury and Biomarkers of Muscle Damage Among Healthy Adults
The purpose of this study is to assess the effects of tart cherry juice to reduce serum biomarkers of inflammation and reduce muscle soreness in healthy adults who undergo a bout of controlled eccentric exercise.
- Trial name
- NCT01547949
- Testing
- tart cultivar Montmorency cherry juice
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis
Effect of Ultrasonic and Diode Laser Activated Irrigation on Postoperative Pain Following Root Canal Treatment
The study is designed to determine whether activation of the irrigant using ultrasonic or diode laser technology can reduce postoperative pain and influence Substance P levels compared with conventional needle irrigation.
- Trial name
- NCT07906808
- Testing
- diode laser activation irrigation, Ultrasonic irrigation activation
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- October 6 University
Pain, Postoperative, Ketamine Adverse Reaction
Efficacy of Ketamine in Post Anesthesia Recovery Room
Observational study to assess efficacy of IV ketamine bolus when used in the post anesthesia recovery unit for uncontrolled pain despite use of opioids.
- Conditions
- Pain, Postoperative, Ketamine Adverse Reaction, Pain, Refractory, Pain, Intractable
- Trial name
- NCT04701008
- Testing
- Ketamine
- Where
- Canada
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Headache
Will the Use of Osteopathic Manipulative Treatments Help Alleviate Headache Pain
PURPOSE The purpose of this research is to determine whether osteopathic manipulative therapy (OMT) is a useful adjunct in evaluation and treatment of headaches.
- Trial name
- NCT01704625
- Testing
- Osteopathic Manipulative Treatment
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Good Samaritan Hospital Medical Center, New York
Tibial Stress Syndrome
Pain Reduction in Tibial Stress Syndrome
This study is intended to determine if compression garments effectively reduce pain in the treatment of tibial stress syndrome (TSS) in the military population.
- Trial name
- NCT03676530
- Testing
- Pro-Tec Shin Splint Compression Wrap
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Brooke Army Medical Center
Necrotic Pulp, Apical Periodontitis
Effect of Diclofenac Sodium Versus Calcium Hydroxide as Intracanal Medication on the Intensity of Postoperative Pain, Bacterial Load Reduction and MMP-9 Levels in Patients With Necrotic Pulp.
the aim of this study is to compare the effect of using Diclofenac Sodium Versus Calcium Hydroxide as Intracanal medication on intensity of postoperative pain, bacterial load reduction after root canal preparation and periapical…
- Trial name
- NCT05582421
- Testing
- Diclofenac Sodium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
Methods That Reduce Pain During Debonding Fixed Orthodontic Appliance
The goal of this clinical trial is to evaluate the effectiveness of four different methods (including the control group) in reducing pain during debonding of fixed orthodontic appliances in participants requiring the removal of…
- Trial name
- NCT05904587
- Testing
- SureSmile® VPro™, ortho technology, sports advantage, thermal forming soft EVA 3mm, cotton roll
- Where
- Iraq
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Post Operative Pain
Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management
This is a randomized controlled trial involving 170 opioid naive women ages 19-40 undergoing scheduled C-sections at Carilion Roanoke Memorial Hospital.
- Trial name
- NCT05360433
- Testing
- Oxycodone oral capsule
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Chronic Post Operative Pain
Prevalence and Risk Factors for Postsurgical Pain After the Open Reduction and Internal Fixation of Lower Limbs.
The objective of this study is to specify the demographic and medical factors that most likely constitute a risk of developing CPSP in the patients with lower limb.
- Trial name
- NCT06136663
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Xuzhou Central Hospital
Opioid-use Disorder, Pain, Acute
Effect of Buprenorphine/Naloxone Continuation on Pain Control and Opioid Use
The aim of this study is to determine the effect of continuation of buprenorphine/naloxone in patients with history of Opioid Use Disorder (OUD) scheduled for surgery compared to reduced dose buprenorphine/naloxone prior to…
- Conditions
- Opioid-use Disorder, Pain, Acute, Surgery
- Trial name
- NCT03266445
- Testing
- buprenorphine/naloxone
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Necrotic Pulp
Effect of Commiphora Myrrh Solution as a Root Canal Irrigant on Post Operative Pain and Bacterial Load Reduction in Necrotic Tooth
Clinically compare the post-operative pain , incidences post-operative swelling , post-operative number of analgesic tablets taken by patient and amount of bacterial load reduction after using 50% Commiphora Myrrh Chemomechanical…
- Trial name
- NCT06310044
- Testing
- Root canal irrigant Commiphora Myrrh 50%
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain
The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
the porpose of study to assess The Effectiveness of Sweet Solution Versus Cryotherapy in Reducing Pain During Administration of Local Anesthesia Among Children
- Trial name
- NCT07002528
- Testing
- sucrose solution, Cryotherapy, topical anesthesia
- Where
- Egypt
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Uterine Bleeding, Uterine Fibroid
Pain Reduction and Ovarian Perfusion Following Uterine Fibroid Embolization
The goal of this study is to assess of Pressure-Enabled Drug Delivery on fibroid treatment in patients undergoing UFE.
- Trial name
- PEDD-UFE (NCT06106633)
- Testing
- TriNaV
- Where
- 2 sites in United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Retinal Disease
Safety and Tolerability of IRX-101 in Patients Receiving Intravitreal Injections
This is a randomized, double-masked study to evaluate the tolerability and safety of IRX-101 versus 5% povidone-iodine (PI) in subjects receiving intravitreal anti-VEGF injections.
- Trial name
- COMFORT (NCT05750589)
- Testing
- IRX-101, Providone-Iodine
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- iRenix Medical, Inc.
Pain
Reducing Brief Thermal and Electrical Pain (Four Study Days)
Ultimately, the purpose of the present study is to help improve pain control in burn patients during wound care and physical therapy, where pain levels with opioids alone are often excessively high.
- Trial name
- 4DO (NCT00682682)
- Testing
- Virtual Reality video distraction, Virtual Reality video game
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
Muscle Soreness, Stiffness of Elbow, Not Elsewhere Classified
The Role of Manual Twirling Acupuncture in Reducing Muscle Pain and Stiffness After Biceps Curling in Healthy Untrained Individuals
Regular physical activity can help to prevent and control non-communicable disease. WHO recommends at least in adults to do moderate-vigorous physical activity includes muscle strengthening.
- Trial name
- NCT06366555
- Testing
- Manual Acupuncture Twirling,
- Where
- Indonesia
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Contracture of Muscle, Thigh
The Effect of Reducing Soreness in Marathon Runners
Delayed onset muscle soreness is defined as the sensition of pain and discomfort in skeletal muscles that occurs after eccentric muscle actions or strenuous exercise like a marathon.
- Trial name
- NCT01512082
- Testing
- Pulsed electromagnetic field devices
- Where
- Denmark
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Northern Orthopaedic Division, Denmark