Clinical trials: Pain Relief
Osteoarthritis, Knee
Radiofrequency Ablation on Pain Relief of Knee Osteoarthritis
Introduction Osteoarthritis (OA) is a chronic, progressive disease with high disability and teratogenicity in the joints. Deterioration of the articular cartilage is the main problem associated with osteoarthritis, which…
- Trial name
- NCT05050396
- Testing
- Cooled versus thermocoagulant Radiofrequency Ablation in pain relief of knee osteoarthritis
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Assiut University
Pain Relief to the Patient Following Abdominal Surgeries
Comparative Evaluation of Quadratus Lumborum and Transverses Abdominis Plane Block for Postoperative Pain Relief in Lower Abdominal Surgeries
Two ultrasound guided techniques to give postoperative pain relief to the patients following abdominal surgeries would be compared using scoring systems for pain relief and scientific methods.
- Trial name
- NCT02910947
- Testing
- ultrasound guided quadratus lumborum or Transversus Abdominis plane block
- Where
- India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pain, Postoperative
Pain Relief After PrimaryTKA
While a majority of people who undergo TKA have significant long-term improvement in functional ability, many patients may experience significant pain in the early postoperative period, which may adversely impact postoperative…
- Trial name
- NCT05751421
- Testing
- Zynrelef (Bupivacaine 60 MG / Meloxicam 1.8 MG) Per 2.3 ML Extended Release Solution, Bupivacaine HCl 0.5% Injectable Solution, primary total knee replacement
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Pain, Acute
Low Dose Methoxyflurane for Pain Relief During Minor Out-patient Urologic Procedures
The participant will be trained to self administer the drug and will be supplied with a PENTHROX commercial inhaler kit .The study nurse will train the participant and supervise its use during the procedure.Immediately following…
- Trial name
- NCT04412642
- Testing
- Methoxyflurane, MEOF
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Pain
Paracetamol / Ibuprofen for Postpartum Pain in the Early Postpartum Period
The investigators will examine the effectiveness of non-opioid analgesia (Paracetamol versus Ibuprofen) in the early postpartum period
- Trial name
- NCT04653506
- Testing
- Paracetamol 1000 mg, Ibuprofen 400 mg
- Where
- Israel
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Pain Relief at First Stage
Pain Relief by Applying TENS on Acupuncture Points During the First Stage of Labour
We aimed to establish the reduction of labor pain by applying TENS at acupuncture points during the first stage of labour, to assess their efficacy, and to ascertain their acceptability.
- Trial name
- NCT00148577
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Pain Control
Gabapentin for Perioperative Pain Relief in Surgical Abortion
Gabapentin preoperative use for evaluation of benefit to reduce pain during and after surgical office-based abortion.
- Trial name
- NCT04292171
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Cryptorchidism
Comparing Oxygen Saturation in Post Anesthesia Care Unit After Different Methods of Pain Relief
To determine the which method of pain relief is better after current anesthesia care.
- Trial name
- NCT00435383
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Oral Pain, Oral Pungent Sensation
Efficacy of Oral HA35 for Rapid Relief of Oral Pain and Pungent Sensation
This prospective, open-label, controlled pilot study evaluates oral 10% 35 kDa hyaluronan (HA35) versus four control interventions (C60 grapeseed oil，normal saline) for relief of capsaicin/AITC-induced oral pain and pungent…
- Conditions
- Oral Pain, Oral Pungent Sensation, Capsaicin-Induced Pain, AITC-Induced Irritation
- Trial name
- NCT07630571
- Testing
- Capsaicin Oral Challenge, Allyl Isothiocyanate (AITC) Oral Challenge, 10% 35 kDa Hyaluronan (HA35) Oral Solution
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nakhia Impex LLC
Dentine Hypersensitivity
Clinical Efficacy of a Toothpaste in Providing Relief From the Pain of Dentinal Hypersensitivity
A study to compare the efficacy of a test dentifrice against a control dentifrice in reducing dentinal hypersensitivity over a two week treatment period.
- Trial name
- NCT01592851
- Testing
- Stannous Fluoride, Sodium Monofluorophosphate
- Where
- United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Auricular Acupressure, Episiotomy Pain
Effects of Auricular Acupressure on Relieving Pain in Postpartum Women With Episiotomy
This randomized, single-blind controlled trial examined the effects of auricular acupressure on postpartum women who underwent episiotomy.
- Trial name
- NCT07277478
- Testing
- auricular patch
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HSIAO AI WEN
Hysteroscopy
Effectiveness of Warm Saline Distension Media on Relieving Pain in Office Hysteroscopy
The aim of the study is to compare the effectiveness of warm saline distension media versus room temperature saline distension media on relieving pain in office hysteroscopy .
- Trial name
- NCT03111563
- Testing
- Warm saline distension media in office hysteroscopy
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief
Comparison of A-PRF vs Bone Wax in Hemostasis, Pain Relief and Healing Following Exodontia
The goal of this clinical trial is to compare the pain relief and healing effect of A-PRF and Bone-wax in patients having mandibular tooth-extractions.
- Conditions
- Post-Extraction Socket Hemostasis, Post-Extraction Socket Pain Relief, Post-Extraction Socket Healing
- Trial name
- NCT05744726
- Testing
- A-PRF, Bone-wax
- Where
- Pakistan
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Altamash Institute of Dental Medicine
Anesthesia, Opioid Use
Opioid-Free Anesthetic for Tonsillectomy
Prospective randomized controlled trial to determine if opioid-free anesthetic for tonsillectomy is non-inferior to standard opioid-containing anesthetic
- Conditions
- Anesthesia, Opioid Use, Tonsillitis, Sleep Disorder
- Trial name
- NCT04528173
- Testing
- Ketorolac, Dexmedetomidine, Morphine
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Labor Pain, Analgesia
Optimal Bupivacaine Dose for Initiation of Labor Epidural Techniques
To estimate the dose of bupivacaine required to achieve initial effective comfort in 90% of patients (ED90) via the epidural (DPE or EPL) technique in women undergoing labor.
- Trial name
- NCT04814537
- Testing
- Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Postoperative Pain
Hydromorphone and C-section
This study will investigate the dose of hydromorphone which will relieve the pain of women following a cesarean section when delivered directly in the area around the spinal cord (i.e., intrathecal injection).
- Trial name
- NCT01598545
- Testing
- Hydromorphone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Pain
An Exploratory Study to Assess the Effects of JNJ-39439335 on the Relief of Pain Using a Thermal-Grill Experimental Model
This exploratory study will use a thermal-grill experimental model to assess the effects of JNJ-39439335 (50 mg, single oral dose) on the relief of pain.
- Trial name
- NCT01006304
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Pain
Clinical Study to Evaluate Efficacy of New Paracetamol Formulation Compared to Ibuprofen in Headache
The purpose of this multi-center study is to assess the efficacy of headache relief of new paracetamol/caffeine formulation compared to placebo and ibuprofen in episodic tension-type headache (ETTH).
- Trial name
- NCT01842633
- Testing
- Paracetamol and Caffeine, Ibuprofen
- Where
- United States
- Volunteers
- 365 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Analgesia
Shoulder Anterior Capsular Block and Intraarticular Steroid Injection Versus Intraarticular Steroid Injection for Enhancing Pain Relief in Adhesive Capsulitis
Improving pain in the patients with adhesive capsulitis by comparing the effect of combined shoulder anterior capsular block and intraarticular steroid injection versus intraarticular steroid injection.
- Trial name
- NCT07235982
- Testing
- Group Group Shoulder anterior capsular block (SHAC), Group intraarticular steroid injection (IASI)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Hematuria, Bladder Ca
Efficacy of the Act of Urination to Relief the Pain During Flexible Cystoscopy Procedure.
This research is about modification during routine cystoscopy (scope in the bladder) procedure [ experimental research ]. The goal of the study is to evaluate patient experience with cystoscopy by using procedural modification to…
- Conditions
- Hematuria, Bladder Ca, Bladder Stone, Urologic Diseases
- Trial name
- NCT05207969
- Testing
- Instruction to urinate
- Where
- Malaysia
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia